Publications for All Faculty
Epinecidin-1 has immunomodulatory effects, facilitating its therapeutic use in a mouse model of Pseudomonas aeruginosa sepsis.
Benchmarking outcomes in the critically injured burn patient.
Targeted mutagenesis of zebrafish antithrombin III triggers disseminated intravascular coagulation and thrombosis, revealing insight into function.
Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing.
In vivo high-resolution magic angle spinning proton NMR spectroscopy of Drosophila melanogaster flies as a model system to investigate mitochondrial dysfunction in Drosophila GST2 mutants.
Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.
Caenorhabditis elegans pathways that surveil and defend mitochondria.
Epitope-tagged protein-based artificial miRNA screens for optimized gene silencing in plants.
MUT-14 and SMUT-1 DEAD Box RNA Helicases Have Overlapping Roles in Germline RNAi and Endogenous siRNA Formation.
Survival From Burns in the New Millennium: 70 Years' Experience From a Single Institution.
Genetic Polymorphisms in Metabolizing Enzymes Modifying the Association Between Smoking and Inflammatory Bowel Diseases.
High-Throughput Screening for Novel Anti-Infectives Using a C. elegans Pathogenesis Model.
Progress Toward Synthetic Cells.
CRISPR-Cas systems for editing, regulating and targeting genomes.
Long-term posttraumatic stress symptoms vary inversely with early opiate dosing in children recovering from serious burns: Effects durable at 4 years.
Enterococcus infection biology: Lessons from invertebrate host models.
The treatment-naive microbiome in new-onset Crohn's disease.
Rapid RNA Exchange in Aqueous Two-Phase System and Coacervate Droplets.
Human Genome-Wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response.
Identification of Host-Targeted Small Molecules That Restrict Intracellular Mycobacterium tuberculosis Growth.
Whole Animal Automated Platform for Drug Discovery against Multi-Drug Resistant Staphylococcus aureus.
IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans.
The Microbiome in Inflammatory Bowel Diseases: Current Status and the Future Ahead.
HDL redox activity is increased in HIV-infected men in association with macrophage activation and noncalcified coronary atherosclerotic plaque.
Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity.