Publications for All Faculty

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Gjini E, Mansour MR, Sander JD, Moritz N, Nguyen AT, Kesarsing M, Gans E, He S, Chen S, Ko M, Kuang YY, Yang S, Zhou Y, Rodig S, Zon LI, Joung JK, Rao A, Look AT

A Zebrafish Model of Myelodysplastic Syndrome Produced Through tet2 Genomic Editing.
Mol Cell Biol. 2015;35(5):789-804 - PMID: 25512612 - PMCID: PMC4323485 - DOI: 10.1128/MCB.00971-14

Ryan CM, Lee A, Kazis LE, Schneider JC, Shapiro GD, Sheridan RL, Meyer WJ, Palmieri T, Pidcock FS, Reilly D, Tompkins RG,

Recovery Trajectories After Burn Injury in Young Adults: Does Burn Size Matter?
J Burn Care Res. 2014;36(1):118-29 - PMID: 25501787 - DOI: 10.1097/BCR.0000000000000214

Jones CN, Moore M, Dimisko L, Alexander A, Ibrahim A, Hassell BA, Warren HS, Tompkins RG, Fagan SP, Irimia D

Spontaneous Neutrophil Migration Patterns during Sepsis after Major Burns.
PLoS One. 2014;9(12):e114509 - PMID: 25489947 - PMCID: PMC4260850 - DOI: 10.1371/journal.pone.0114509

Wang MC, Oakley HD, Carr CE, Sowa JN, Ruvkun G

Gene Pathways That Delay Caenorhabditis elegans Reproductive Senescence.
PLoS Genet. 2014;10(12):e1004752 - PMID: 25474471 - PMCID: PMC4256158 - DOI: 10.1371/journal.pgen.1004752

Knights D, Silverberg MS, Weersma RK, Gevers D, Dijkstra G, Huang H, Tyler AD, van Sommeren S, Imhann F, Stempak JM, Huang H, Vangay P, Al-Ghalith GA, Russell C, Sauk J, Knight J, Daly MJ, Huttenhower C, Xavier RJ

Complex host genetics influence the microbiome in inflammatory bowel disease.
Genome Med. 2014;6(12):107 - PMID: 25587358 - PMCID: PMC4292994 - DOI: 10.1186/s13073-014-0107-1

O'Rourke EJ, Ruvkun G

Corrigendum: MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability.
Nat Cell Biol. 2014;17(1):104 - PMID: 25534088

Hentrich C, Szostak JW

Controlled growth of filamentous fatty acid vesicles under flow.
Langmuir. 2014;30(49):14916-25 - PMID: 25402759 - PMCID: PMC4985002 - DOI: 10.1021/la503933x

Li JF, Zhang D, Sheen J

Cas9-Based Genome Editing in Arabidopsis and Tobacco.
Methods Enzymol. 2014;546:459-72 - PMID: 25398353 - DOI: 10.1016/B978-0-12-801185-0.00022-2

Fu Y, Reyon D, Joung JK

Targeted genome editing in human cells using CRISPR/Cas nucleases and truncated guide RNAs.
Methods Enzymol. 2014;546:21-45 - PMID: 25398334 - DOI: 10.1016/B978-0-12-801185-0.00002-7

Carter EA, Paul K, Bonab AA, Tompkins RG, Fischman AJ

Effect of exercise on burn-induced changes in tissue-specific glucose metabolism.
J Burn Care Res. 2014;35(6):470-3 - PMID: 24476988 - PMCID: PMC4113562 - DOI: 10.1097/BCR.0000000000000036

Paulus GL, Xavier RJ

Autophagy and checkpoints for intracellular pathogen defense.
Curr Opin Gastroenterol. 2015;31(1):14-23 - PMID: 25394238 - PMCID: PMC4330559 - DOI: 10.1097/MOG.0000000000000134

Buffen K, Oosting M, Quintin J, Ng A, Kleinnijenhuis J, Kumar V, van de Vosse E, Wijmenga C, van Crevel R, Oosterwijk E, Grotenhuis AJ, Vermeulen SH, Kiemeney LA, van de Veerdonk FL, Chamilos G, Xavier RJ, van der Meer JW, Netea MG, Joosten LA

Autophagy Controls BCG-Induced Trained Immunity and the Response to Intravesical BCG Therapy for Bladder Cancer.
PLoS Pathog. 2014;10(10):e1004485 - PMID: 25356988 - PMCID: PMC4214925 - DOI: 10.1371/journal.ppat.1004485

Zuris JA, Thompson DB, Shu Y, Guilinger JP, Bessen JL, Hu JH, Maeder ML, Joung JK, Chen ZY, Liu DR

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo.
Nat Biotechnol. 2015;33(1):73-80 - PMID: 25357182 - PMCID: PMC4289409 - DOI: 10.1038/nbt.3081

Kotz KT, Petrofsky AC, Haghgooie R, Granier R, Toner M, Tompkins RG

Inertial focusing cytometer with integrated optics for particle characterization.
Technology (Singap World Sci). 2014;1(1):27-36 - PMID: 25346940 - PMCID: PMC4206911 - DOI: 10.1142/S233954781350009X

Kleinnijenhuis J, Quintin J, Preijers F, Joosten LA, Jacobs C, Xavier RJ, van der Meer JW, van Crevel R, Netea MG

BCG-induced trained immunity in NK cells: Role for non-specific protection to infection.
Clin Immunol. 2014;155(2):213-219 - PMID: 25451159 - PMCID: PMC5084088 - DOI: 10.1016/j.clim.2014.10.005

Kumar V, Wijmenga C, Xavier RJ

Genetics of immune-mediated disorders: from genome-wide association to molecular mechanism.
Curr Opin Immunol. 2014;31C:51-57 - PMID: 25458995 - PMCID: PMC5080657 - DOI: 10.1016/j.coi.2014.09.007

Govindan JA, Ruvkun G

Pathogens.
Virulence. 2014;5(7):ePub - PMID: 25290904 - PMCID: PMC4189874

Zhang XC, Millet Y, Ausubel FM, Borowsky M

Next-Gen Sequencing-Based Mapping and Identification of Ethyl Methanesulfonate-Induced Mutations in Arabidopsis thaliana.
Curr Protoc Mol Biol. 2014;108:7.18.1-7.18.16 - PMID: 25271717 - DOI: 10.1002/0471142727.mb0718s108

Budin I, Prwyes N, Zhang N, Szostak JW

Chain-Length Heterogeneity Allows for the Assembly of Fatty Acid Vesicles in Dilute Solutions.
Biophys J. 2014;107(7):1582-1590 - PMID: 25296310 - PMCID: PMC4190651 - DOI: 10.1016/j.bpj.2014.07.067

Ausubel FM

Twists and turns: my career path and concerns about the future.
Genetics. 2014;198(2):431-4 - PMID: 25316778 - PMCID: PMC4196596 - DOI: 10.1534/genetics.114.169102

Govindan JA, Ruvkun G

Pathogens.
Virulence. 2014;5(7):695-696 - PMID: 25513769 - PMCID: PMC4189874 - DOI: 10.4161/viru.36667

Tsai SQ, Iafrate AJ, Joung JK

Genome editing: a tool for research and therapy: towards a functional understanding of variants for molecular diagnostics using genome editing.
Nat Med. 2014;20(10):1103-4 - PMID: 25295940 - DOI: 10.1038/nm.3722

Liao J, Jijon HB, Kim IR, Goel G, Doan A, Sokol H, Bauer H, Herrmann BG, Lassen KG, Xavier RJ

An Image-Based Genetic Assay Identifies Genes in T1D Susceptibility Loci Controlling Cellular Antiviral Immunity in Mouse.
PLoS One. 2014;9(9):e108777 - PMID: 25268627 - PMCID: PMC4182575 - DOI: 10.1371/journal.pone.0108777

Platt RJ, Chen S, Zhou Y, Yim MJ, Swiech L, Kempton HR, Dahlman JE, Parnas O, Eisenhaure TM, Jovanovic M, Graham DB, Jhunjhunwala S, Heidenreich M, Xavier RJ, Langer R, Anderson DG, Hacohen N, Regev A, Feng G, Sharp PA, Zhang F

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling.
Cell. 2014;159(2):440-55 - PMID: 25263330 - PMCID: PMC4265475 - DOI: 10.1016/j.cell.2014.09.014

Draberova L, Bugajev V, Potuckova L, Halova I, Bambouskova M, Polakovicova I, Xavier RJ, Seed B, Draber P

Transmembrane adaptor protein PAG/CBP is involved in both positive and negative regulation of mast cell signaling.
Mol Cell Biol. 2014;34(23):4285-300 - PMID: 25246632 - PMCID: PMC4248753 - DOI: 10.1128/MCB.00983-14
Total: 2505