Publications for All Faculty

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Jayamani E, Rajamuthiah R, Larkins-Ford J, Fuchs BB, Conery AL, Vilcinskas A, Ausubel FM, Mylonakis E

Insect-derived Cecropins Display Activity Against Acinetobacter baumannii in a Whole-Animal High-Throughput Caenorhabditis elegans Model.
Antimicrob Agents Chemother. 2015;59(3):1728-37 - PMID: 25583713 - PMCID: PMC4325797 - DOI: 10.1128/AAC.04198-14

Palsson-McDermott EM, Curtis AM, Goel G, Lauterbach MA, Sheedy FJ, Gleeson LE, van den Bosch MW, Quinn SR, Domingo-Fernandez R, Johnson DG, Jiang J, Israelsen WJ, Keane J, Thomas C, Clish C, Vanden Heiden M, Xavier RJ, O'Neill LA

Pyruvate Kinase M2 Regulates Hif-1? Activity and IL-1? Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages.
Cell Metab. 2015;21(1):65-80 - PMID: 25565206 - PMCID: PMC5198835 - DOI: 10.1016/j.cmet.2014.12.005

Jeschke MG, Pinto R, Kraft R, Nathens AB, Finnerty CC, Gamelli RL, Gibran NS, Klein MB, Arnoldo BD, Tompkins RG, Herndon DN,

Morbidity and Survival Probability in Burn Patients in Modern Burn Care.
Crit Care Med. 2015;43(4):808-15 - PMID: 25559438 - PMCID: PMC4359665 - DOI: 10.1097/CCM.0000000000000790

Osborn MJ, Gabriel R, Webber BR, DeFeo AP, McElroy AN, Jarjour J, Starker CG, Wagner JE, Joung JK, Voytas DF, von Kalle C, Schmidt M, Blazar BR, Tolar J

Fanconi Anemia Gene Editing by the CRISPR/Cas9 System.
Hum Gene Ther. 2015;26(2):114-26 - PMID: 25545896 - PMCID: PMC4326027 - DOI: 10.1089/hum.2014.111

Warren HS, Tompkins RG, Moldawer LL, Seok J, Xu W, Mindrinos MN, Maier RV, Xiao W, Davis RW

Mice are not men.
Proc Natl Acad Sci U S A. 2015;112(4):E345 - PMID: 25540422 - PMCID: PMC4313842 - DOI: 10.1073/pnas.1414857111

Adamala K, Engelhart AE, Szostak JW

Generation of functional RNAs from inactive oligonucleotide complexes by non-enzymatic primer extension.
J Am Chem Soc. 2015;137(1):483-9 - PMID: 25521912 - PMCID: PMC4984999 - DOI: 10.1021/ja511564d

Guo AY, Stevens BW, Wilson RG, Russell CN, Cohen MA, Sturgeon HC, Thornton A, Giallourakis C, Khalili H, Nguyen DD, Sauk J, Yajnik V, Xavier RJ, Ananthakrishnan AN

Early life environment and natural history of inflammatory bowel diseases.
BMC Gastroenterol. 2014;14(1):216 - PMID: 25510175 - PMCID: PMC4300207 - DOI: 10.1186/s12876-014-0216-8

Tsai SQ, Zheng Z, Nguyen NT, Liebers M, Topkar VV, Thapar V, Wyvekens N, Khayter C, Iafrate AJ, Le LP, Aryee MJ, Joung JK

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.
Nat Biotechnol. 2015;33(2):187-197 - PMID: 25513782 - PMCID: PMC4320685 - DOI: 10.1038/nbt.3117

Lo J, Rosenberg ES, Fitzgerald ML, Bazner SB, Ihenachor EJ, Hawxhurst V, Borkowska AH, Wei J, Zimmerman CO, Burdo TH, Williams KC, Freeman MW, Grinspoon SK

High-density lipoprotein-mediated cholesterol efflux capacity is improved by treatment with antiretroviral therapy in acute human immunodeficiency virus infection.
Open Forum Infect Dis. 2014;1(3):ofu108 - PMID: 25734176 - PMCID: PMC4324225 - DOI: 10.1093/ofid/ofu108

Gjini E, Mansour MR, Sander JD, Moritz N, Nguyen AT, Kesarsing M, Gans E, He S, Chen S, Ko M, Kuang YY, Yang S, Zhou Y, Rodig S, Zon LI, Joung JK, Rao A, Look AT

A Zebrafish Model of Myelodysplastic Syndrome Produced Through tet2 Genomic Editing.
Mol Cell Biol. 2015;35(5):789-804 - PMID: 25512612 - PMCID: PMC4323485 - DOI: 10.1128/MCB.00971-14

Ryan CM, Lee A, Kazis LE, Schneider JC, Shapiro GD, Sheridan RL, Meyer WJ, Palmieri T, Pidcock FS, Reilly D, Tompkins RG,

Recovery Trajectories After Burn Injury in Young Adults: Does Burn Size Matter?
J Burn Care Res. 2014;36(1):118-29 - PMID: 25501787 - DOI: 10.1097/BCR.0000000000000214

Jones CN, Moore M, Dimisko L, Alexander A, Ibrahim A, Hassell BA, Warren HS, Tompkins RG, Fagan SP, Irimia D

Spontaneous Neutrophil Migration Patterns during Sepsis after Major Burns.
PLoS One. 2014;9(12):e114509 - PMID: 25489947 - PMCID: PMC4260850 - DOI: 10.1371/journal.pone.0114509

Wang MC, Oakley HD, Carr CE, Sowa JN, Ruvkun G

Gene Pathways That Delay Caenorhabditis elegans Reproductive Senescence.
PLoS Genet. 2014;10(12):e1004752 - PMID: 25474471 - PMCID: PMC4256158 - DOI: 10.1371/journal.pgen.1004752

Knights D, Silverberg MS, Weersma RK, Gevers D, Dijkstra G, Huang H, Tyler AD, van Sommeren S, Imhann F, Stempak JM, Huang H, Vangay P, Al-Ghalith GA, Russell C, Sauk J, Knight J, Daly MJ, Huttenhower C, Xavier RJ

Complex host genetics influence the microbiome in inflammatory bowel disease.
Genome Med. 2014;6(12):107 - PMID: 25587358 - PMCID: PMC4292994 - DOI: 10.1186/s13073-014-0107-1

O'Rourke EJ, Ruvkun G

Corrigendum: MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability.
Nat Cell Biol. 2014;17(1):104 - PMID: 25534088

Hentrich C, Szostak JW

Controlled growth of filamentous fatty acid vesicles under flow.
Langmuir. 2014;30(49):14916-25 - PMID: 25402759 - PMCID: PMC4985002 - DOI: 10.1021/la503933x

Li JF, Zhang D, Sheen J

Cas9-Based Genome Editing in Arabidopsis and Tobacco.
Methods Enzymol. 2014;546:459-72 - PMID: 25398353 - DOI: 10.1016/B978-0-12-801185-0.00022-2

Fu Y, Reyon D, Joung JK

Targeted genome editing in human cells using CRISPR/Cas nucleases and truncated guide RNAs.
Methods Enzymol. 2014;546:21-45 - PMID: 25398334 - DOI: 10.1016/B978-0-12-801185-0.00002-7

Carter EA, Paul K, Bonab AA, Tompkins RG, Fischman AJ

Effect of exercise on burn-induced changes in tissue-specific glucose metabolism.
J Burn Care Res. 2014;35(6):470-3 - PMID: 24476988 - PMCID: PMC4113562 - DOI: 10.1097/BCR.0000000000000036

Paulus GL, Xavier RJ

Autophagy and checkpoints for intracellular pathogen defense.
Curr Opin Gastroenterol. 2015;31(1):14-23 - PMID: 25394238 - PMCID: PMC4330559 - DOI: 10.1097/MOG.0000000000000134

Buffen K, Oosting M, Quintin J, Ng A, Kleinnijenhuis J, Kumar V, van de Vosse E, Wijmenga C, van Crevel R, Oosterwijk E, Grotenhuis AJ, Vermeulen SH, Kiemeney LA, van de Veerdonk FL, Chamilos G, Xavier RJ, van der Meer JW, Netea MG, Joosten LA

Autophagy Controls BCG-Induced Trained Immunity and the Response to Intravesical BCG Therapy for Bladder Cancer.
PLoS Pathog. 2014;10(10):e1004485 - PMID: 25356988 - PMCID: PMC4214925 - DOI: 10.1371/journal.ppat.1004485

Zuris JA, Thompson DB, Shu Y, Guilinger JP, Bessen JL, Hu JH, Maeder ML, Joung JK, Chen ZY, Liu DR

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo.
Nat Biotechnol. 2015;33(1):73-80 - PMID: 25357182 - PMCID: PMC4289409 - DOI: 10.1038/nbt.3081

Kotz KT, Petrofsky AC, Haghgooie R, Granier R, Toner M, Tompkins RG

Inertial focusing cytometer with integrated optics for particle characterization.
Technology (Singap World Sci). 2014;1(1):27-36 - PMID: 25346940 - PMCID: PMC4206911 - DOI: 10.1142/S233954781350009X

Kleinnijenhuis J, Quintin J, Preijers F, Joosten LA, Jacobs C, Xavier RJ, van der Meer JW, van Crevel R, Netea MG

BCG-induced trained immunity in NK cells: Role for non-specific protection to infection.
Clin Immunol. 2014;155(2):213-219 - PMID: 25451159 - PMCID: PMC5084088 - DOI: 10.1016/j.clim.2014.10.005

Kumar V, Wijmenga C, Xavier RJ

Genetics of immune-mediated disorders: from genome-wide association to molecular mechanism.
Curr Opin Immunol. 2014;31C:51-57 - PMID: 25458995 - PMCID: PMC5080657 - DOI: 10.1016/j.coi.2014.09.007
Total: 2489