Publications for All Faculty

Sort by:
Reset

Ryan CM, Lee AF, Kazis LE, Shapiro GD, Schneider JC, Goverman J, Fagan SP, Wang C, Kim J, Sheridan RL, Tompkins RG

Is Real-Time Feedback of Burn-Specific Patient-Reported Outcome Measures in Clinical Settings Practical and Useful? A Pilot Study Implementing the Young Adult Burn Outcome Questionnaire.
J Burn Care Res. 2015;37(1):64-74 - PMID: 26284638 - DOI: 10.1097/BCR.0000000000000287

Phillips CM, Brown KC, Montgomery BE, Ruvkun G, Montgomery TA

piRNAs and piRNA-Dependent siRNAs Protect Conserved and Essential C. elegans Genes from Misrouting into the RNAi Pathway.
Dev Cell. 2015;34(4):457-465 - PMID: 26279487 - PMCID: PMC4550515 - DOI: 10.1016/j.devcel.2015.07.009

Hubbard BP, Badran AH, Zuris JA, Guilinger JP, Davis KM, Chen L, Tsai SQ, Sander JD, Joung JK, Liu DR

Continuous directed evolution of DNA-binding proteins to improve TALEN specificity.
Nat Methods. 2015;12(10):939-942 - PMID: 26258293 - PMCID: PMC4589463 - DOI: 10.1038/nmeth.3515

Larsen AT, Fahrenbach AC, Sheng J, Pian J, Szostak JW

Thermodynamic insights into 2-thiouridine-enhanced RNA hybridization.
Nucleic Acids Res. 2015;43(16):7675-87 - PMID: 26240387 - PMCID: PMC4652770 - DOI: 10.1093/nar/gkv761

Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ

Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases.
Inflamm Bowel Dis. 2015;21(11):2507-2514 - PMID: 26241000 - PMCID: PMC4615315 - DOI: 10.1097/MIB.0000000000000524

Haney CH, Ausubel FM

MICROBIOME. Plant microbiome blueprints.
Science. 2015;349(6250):788-9 - PMID: 26293938 - DOI: 10.1126/science.aad0092

Korem T, Zeevi D, Suez J, Weinberger A, Avnit-Sagi T, Pompan-Lotan M, Matot E, Jona G, Harmelin A, Cohen N, Sirota-Madi A, Thaiss CA, Pevsner-Fischer M, Sorek R, Xavier R, Elinav E, Segal E

Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples.
Science. 2015;349(6252):1101-6 - PMID: 26229116 - PMCID: PMC5087275 - DOI: 10.1126/science.aac4812

Kamat NP, Tobé S, Hill IT, Szostak JW

Electrostatic Localization of RNA to Protocell Membranes by Cationic Hydrophobic Peptides.
Angew Chem Int Ed Engl. 2015;54(40):11735-11739 - PMID: 26223820 - PMCID: PMC4600236 - DOI: 10.1002/anie.201505742

Graham DB, Becker CE, Doan A, Goel G, Villablanca EJ, Knights D, Mok A, Ng AC, Doench JG, Root DE, Clish CB, Xavier RJ

Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst.
Nat Commun. 2015;6:7838 - PMID: 26194095 - PMCID: PMC4518307 - DOI: 10.1038/ncomms8838

Groen SC, Humphrey PT, Chevasco D, Ausubel FM, Pierce NE, Whiteman NK

Pseudomonas syringae enhances herbivory by suppressing the reactive oxygen burst in Arabidopsis.
J Insect Physiol. 2016;84:90-102 - PMID: 26205072 - PMCID: PMC4721946 - DOI: 10.1016/j.jinsphys.2015.07.011

Kuo SY, Castoreno AB, Aldrich LN, Lassen KG, Goel G, Dan?ík V, Kuballa P, Latorre I, Conway KL, Sarkar S, Maetzel D, Jaenisch R, Clemons PA, Schreiber SL, Shamji AF, Xavier RJ

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics.
Proc Natl Acad Sci U S A. 2015;112(31):E4281-7 - PMID: 26195741 - PMCID: PMC4534235 - DOI: 10.1073/pnas.1512289112

Pringle PL, Stewart KO, Peloquin JM, Sturgeon HC, Nguyen D, Sauk J, Garber JJ, Yajnik V, Ananthakrishnan AN, Chan AT, Xavier RJ, Khalili H

Body Mass Index, Genetic Susceptibility, and Risk of Complications Among Individuals with Crohn's Disease.
Inflamm Bowel Dis. 2015;21(10):2304-2310 - PMID: 26181430 - PMCID: PMC4567407 - DOI: 10.1097/MIB.0000000000000498

Baxt LA, Xavier RJ

Role of Autophagy in the Maintenance of Intestinal Homeostasis.
Gastroenterology. 2015;149(3):553-62 - PMID: 26170139 - PMCID: PMC4550567 - DOI: 10.1053/j.gastro.2015.06.046

Joung JK

Unwanted mutations: Standards needed for gene-editing errors.
Nature. 2015;523(7559):158 - PMID: 26156364 - DOI: 10.1038/523158a

Bakris GL, Pitt B, Weir MR, Freeman MW, Mayo MR, Garza D, Stasiv Y, Zawadzki R, Berman L, Bushinsky DA,

Effect of Patiromer on Serum Potassium Level in Patients With Hyperkalemia and Diabetic Kidney Disease: The AMETHYST-DN Randomized Clinical Trial.
JAMA. 2015;314(2):151-61 - PMID: 26172895 - DOI: 10.1001/jama.2015.7446

Ramezani A, Dubrovsky L, Pushkarsky T, Sviridov D, Karandish S, Raj DS, Fitzgerald ML, Bukrinsky M

Stimulation of Liver X Receptor Has Potent Anti-HIV Effects in a Humanized Mouse Model.
J Pharmacol Exp Ther. 2015;354(3):376-83 - PMID: 26126533 - PMCID: PMC4538872 - DOI: 10.1124/jpet.115.224485

Kleinstiver BP, Prew MS, Tsai SQ, Topkar VV, Nguyen NT, Zheng Z, Gonzales AP, Li Z, Peterson RT, Yeh JJ, Aryee MJ, Joung JK

Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
Nature. 2015;523(7561):481-5 - PMID: 26098369 - PMCID: PMC4540238 - DOI: 10.1038/nature14592

Begun J, Lassen KG, Jijon HB, Baxt LA, Goel G, Heath RJ, Ng A, Tam JM, Kuo SY, Villablanca EJ, Fagbami L, Oosting M, Kumar V, Schenone M, Carr SA, Joosten LA, Vyas JM, Daly MJ, Netea MG, Brown GD, Wijmenga C, Xavier RJ

Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy.
Cell Rep. 2015;11(12):1905-1918 - PMID: 26095365 - PMCID: PMC4507440 - DOI: 10.1016/j.celrep.2015.05.045

Wyvekens N, Topkar VV, Khayter C, Joung JK, Tsai SQ

Dimeric CRISPR RNA-guided FokI-dCas9 nucleases (RFNs) directed by truncated gRNAs for highly specific genome editing.
Hum Gene Ther. 2015;26(7):425-431 - PMID: 26068112 - PMCID: PMC4509490 - DOI: 10.1089/hum.2015.084

Rajamuthiah R, Jayamani E, Conery AL, Fuchs BB, Kim W, Johnston T, Vilcinskas A, Ausubel FM, Mylonakis E

A Defensin from the Model Beetle Tribolium castaneum Acts Synergistically with Telavancin and Daptomycin against Multidrug Resistant Staphylococcus aureus.
PLoS One. 2015;10(6):e0128576 - PMID: 26062137 - PMCID: PMC4465704 - DOI: 10.1371/journal.pone.0128576

Quévrain E, Maubert MA, Michon C, Chain F, Marquant R, Tailhades J, Miquel S, Carlier L, Bermúdez-Humarán LG, Pigneur B, Lequin O, Kharrat P, Thomas G, Rainteau D, Aubry C, Breyner N, Afonso C, Lavielle S, Grill JP, Chassaing G, Chatel JM, Trugnan G, Xavier R, Langella P, Sokol H, Seksik P

Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn's disease.
Gut. 2016;65(3):415-25 - PMID: 26045134 - PMCID: PMC5136800 - DOI: 10.1136/gutjnl-2014-307649

Kim W, Conery AL, Rajamuthiah R, Fuchs BB, Ausubel FM, Mylonakis E

Identification of an Antimicrobial Agent Effective against Methicillin-Resistant Staphylococcus aureus Persisters Using a Fluorescence-Based Screening Strategy.
PLoS One. 2015;10(6):e0127640 - PMID: 26039584 - PMCID: PMC4454602 - DOI: 10.1371/journal.pone.0127640

Causton B, Ramadas RA, Cho JL, Jones K, Pardo-Saganta A, Rajagopal J, Xavier RJ, Medoff BD

CARMA3 Is Critical for the Initiation of Allergic Airway Inflammation.
J Immunol. 2015;195(2):683-94 - PMID: 26041536 - PMCID: PMC4489191 - DOI: 10.4049/jimmunol.1402983

Adamala K, Engelhart AE, Kamat NP, Jin L, Szostak JW

Construction of a liposome dialyzer for the preparation of high-value, small-volume liposome formulations.
Nat Protoc. 2015;10(6):927-938 - PMID: 26020615 - PMCID: PMC4982460 - DOI: 10.1038/nprot.2015.054

Rahman SH, Kuehle J, Reimann C, Mlambo T, Alzubi J, Maeder ML, Riedel H, Fisch P, Cantz T, Rudolph C, Mussolino C, Joung JK, Schambach A, Cathomen T

Rescue of DNA-PK Signaling and T-Cell Differentiation by Targeted Genome Editing in a prkdc Deficient iPSC Disease Model.
PLoS Genet. 2015;11(5):e1005239 - PMID: 26000857 - PMCID: PMC4441453 - DOI: 10.1371/journal.pgen.1005239
Total: 2498