Publications for All Faculty
Small-molecule probe for IBD risk variant GPR65 I231L alters cytokine signaling networks through positive allosteric modulation.
Caenorhabditis elegans SynMuv B gene activity is down-regulated during a viral infection to enhance RNA interference.
Mutations in nucleotide metabolism genes bypass proteasome defects in png-1/NGLY1-deficient Caenorhabditis elegans.
The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells.
3-Hydroxykynurenine targets kainate receptors to promote defense against infection.
Discovery of disease-adapted bacterial lineages in inflammatory bowel diseases.
CMTR-1 RNA methyltransferase mutations activate widespread expression of a dopaminergic neuron-specific mitochondrial complex I gene.
Perturbation-Specific Transcriptional Mapping facilitates unbiased target elucidation of antibiotics.
An esophagus cell atlas reveals dynamic rewiring during active eosinophilic esophagitis and remission.
Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
Gut microbiome and metabolome profiling in Framingham heart study reveals cholesterol-metabolizing bacteria.
"Multiplexed screen identifies a Pseudomonas aeruginosa -specific small molecule targeting the outer membrane protein OprH and its interaction with LPS".
Translational genetics identifies a phosphorylation switch in CARD9 required for innate inflammatory responses.
Structure-guided aminoacylation and assembly of chimeric RNAs.
Absence of a pancreatic microbiome in intraductal papillary mucinous neoplasm.
Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans
Transient states during the annealing of mismatched and bulged oligonucleotides.
A dual-plasmid CRISPR/Cas9-based method for rapid and efficient genetic disruption in Mycobacterium abscessus.
Results from a Phase 1 Study Assessing the Pharmacokinetics of the Aldosterone Synthase Inhibitor Baxdrostat in Participants with Varying Degrees of Renal Function.
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying.
Genetic factors affecting storage and utilization of lipids during dormancy in Mycobacterium tuberculosis.
Preliminary evidence for chaotic signatures in host-microbe interactions.
The new horizon of plant auxin signaling via cell-surface co-receptors.
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism.
Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course.
