Publications for All Faculty
Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine.
Burn-induced muscle metabolic derangements and mitochondrial dysfunction are associated with activation of HIF-1α and mTORC1: Role of protein farnesylation.
Nucleic Acid Extraction from Synthetic Mars Analog Soils for in situ Life Detection.
UV-light-driven prebiotic synthesis of iron-sulfur clusters.
Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children.
A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Indoleacrylic Acid Produced by Commensal Peptostreptococcus Species Suppresses Inflammation.
Fine-mapping inflammatory bowel disease loci to single-variant resolution.
E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.
Characterization of a Francisella tularensis-Caenorhabditis elegans pathosystem for the evaluation of therapeutic compounds.
Common and Potentially Prebiotic Origin for Precursors of Nucleotide Synthesis and Activation.
Dissecting the human microbiome with single-cell genomics.
Genome editing of factor X in zebrafish reveals unexpected tolerance of severe defects in the common pathway.
Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota.
Divergent prebiotic synthesis of pyrimidine and 8-oxo-purine ribonucleotides.
Adult-onset, chronic, cyclic thrombocytopenia in a Rhesus macaque (Macaca mulatta) after dengue virus vaccination and viral challenge.
The Narrow Road to the Deep Past.
Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence.
Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies.
Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks.
CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR-Cas9 nuclease off-targets.
Gut Microbiome Function Predicts Response to Anti-integrin Biologic Therapy in Inflammatory Bowel Diseases.
Nucleic acid detection with CRISPR-Cas13a/C2c2.
Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease.
