Publications for All Faculty
Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.
An Anti-Persister Strategy for the Treatment of Chronic Pseudomonas aeruginosa Infections.
Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9.
The Ubiquitin Ligase Smurf1 Functions in Selective Autophagy of Mycobacterium tuberculosis and Anti-tuberculous Host Defense.
Investment in secreted enzymes during nutrient-limited growth is utility dependent.
SHANK3 Regulates Intestinal Barrier Function Through Modulating ZO-1 Expression Through the PKCε-dependent Pathway.
Human genetic variation and the gut microbiome in disease.
Erratum: E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.
Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells.
NIH Centers for Accelerated Innovations Program: principles, practices, successes and challenges.
A sharp Pif1-dependent threshold separates DNA double-strand breaks from critically short telomeres.
Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine.
Burn-induced muscle metabolic derangements and mitochondrial dysfunction are associated with activation of HIF-1α and mTORC1: Role of protein farnesylation.
Nucleic Acid Extraction from Synthetic Mars Analog Soils for in situ Life Detection.
UV-light-driven prebiotic synthesis of iron-sulfur clusters.
Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children.
A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Indoleacrylic Acid Produced by Commensal Peptostreptococcus Species Suppresses Inflammation.
Fine-mapping inflammatory bowel disease loci to single-variant resolution.
E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.
Characterization of a Francisella tularensis-Caenorhabditis elegans pathosystem for the evaluation of therapeutic compounds.
Common and Potentially Prebiotic Origin for Precursors of Nucleotide Synthesis and Activation.
Dissecting the human microbiome with single-cell genomics.
Genome editing of factor X in zebrafish reveals unexpected tolerance of severe defects in the common pathway.
