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Newman MA, Ji F, Fischer SEJ, Anselmo A, Sadreyev RI, Ruvkun G

The surveillance of pre-mRNA splicing is an early step in C. elegans RNAi of endogenous genes.
Genes Dev. 2018;32(9-10):670-681 - PMID: 29739806 - PMCID: PMC6004069 - DOI: 10.1101/gad.311514.118

Burke KE, Khalili H, Garber JJ, Haritunians T, McGovern DPB, Xavier RJ, Ananthakrishnan AN

Genetic Markers Predict Primary Nonresponse and Durable Response to Anti-Tumor Necrosis Factor Therapy in Ulcerative Colitis.
Inflamm Bowel Dis. 2018;24(8):1840-1848 - PMID: 29718226 - PMCID: PMC6128143 - DOI: 10.1093/ibd/izy083

Kasotakis G, Starr N, Nelson E, Sarkar B, Burke PA, Remick DG, Tompkins RG, Inflammation and Host Response to Injury Investigators

Platelet transfusion increases risk for acute respiratory distress syndrome in non-massively transfused blunt trauma patients.
Eur J Trauma Emerg Surg. 2019;45(4):671-679 - PMID: 29627883 - DOI: 10.1007/s00068-018-0953-4

O'Flaherty DK, Kamat NP, Mirza FN, Li L, Prywes N, Szostak JW

Copying of mixed sequence RNA templates inside model protocells.
J Am Chem Soc. 2018;140(15):5171-5178 - PMID: 29608310 - PMCID: PMC7547884 - DOI: 10.1021/jacs.8b00639

Brown EM, Xavier RJ

Without Adaptive Immunity, There's a Cost to Responding STAT.
Cell Metab. 2018;27(4):705-707 - PMID: 29617636 - DOI: 10.1016/j.cmet.2018.03.011

Canver MC, Joung JK, Pinello L

Impact of Genetic Variation on CRISPR-Cas Targeting.
CRISPR J. 2018;1:159-170 - PMID: 31021199 - PMCID: PMC6319324 - DOI: 10.1089/crispr.2017.0016

Lareau CA, Clement K, Hsu JY, Pattanayak V, Joung JK, Aryee MJ, Pinello L

Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo".
Nat Methods. 2018;15(4):238-239 - PMID: 29600992 - PMCID: PMC7784551 - DOI: 10.1038/nmeth.4541

Kim W, Zhu W, Hendricks GL, Van Tyne D, Steele AD, Keohane CE, Fricke N, Conery AL, Shen S, Pan W, Lee K, Rajamuthiah R, Fuchs BB, Vlahovska PM, Wuest WM, Gilmore MS, Gao H, Ausubel FM, Mylonakis E

A new class of synthetic retinoid antibiotics effective against bacterial persisters.
Nature. 2018;556(7699):103-107 - PMID: 29590091 - PMCID: PMC6462414 - DOI: 10.1038/nature26157

Verma MS, Fink MJ, Salmon GL, Fornelos N, Ohara TE, Ryu SH, Vlamakis H, Xavier RJ, Stappenbeck TS, Whitesides GM

A common mechanism links activities of butyrate in the colon.
ACS Chem Biol. 2018;13(5):1291-1298 - PMID: 29584955 - DOI: 10.1021/acschembio.8b00073

Mojarro A, Hachey J, Ruvkun G, Zuber MT, Carr CE

CarrierSeq: a sequence analysis workflow for low-input nanopore sequencing.
BMC Bioinformatics. 2018;19(1):108 - PMID: 29587645 - PMCID: PMC5872496 - DOI: 10.1186/s12859-018-2124-3

Clatworthy AE, Romano KP, Hung DT

Whole-organism phenotypic screening for anti-infectives promoting host health.
Nat Chem Biol. 2018;14(4):331-341 - PMID: 29556098 - PMCID: PMC9843822 - DOI: 10.1038/s41589-018-0018-3

Johns NI, Gomes ALC, Yim SS, Yang A, Blazejewski T, Smillie CS, Smith MB, Alm EJ, Kosuri S, Wang HH

Metagenomic mining of regulatory elements enables programmable species-selective gene expression.
Nat Methods. 2018;15(5):323-329 - PMID: 30052624 - PMCID: PMC6065261 - DOI: 10.1038/nmeth.4633

Haller S, Franchet A, Hakkim A, Chen J, Drenkard E, Yu S, Schirmeier S, Li Z, Martins N, Ausubel FM, Liégeois S, Ferrandon D

Quorum-sensing regulator RhlR but not its autoinducer RhlI enablesPseudomonasto evade opsonization.
EMBO Rep. 2018;19(5):ePub - PMID: 29523648 - PMCID: PMC5934776 - DOI: 10.15252/embr.201744880

Jin L, Kamat NP, Jena S, Szostak JW

Fatty Acid/Phospholipid Blended Membranes: A Potential Intermediate State in Protocellular Evolution.
Small. 2018;14(15):e1704077 - PMID: 29479815 - PMCID: PMC6278924 - DOI: 10.1002/smll.201704077

Yuen GJ, Ausubel FM

Both live and dead Enterococci activate Caenorhabditis elegans host defense via immune and stress pathways.
Virulence. 2018;9(1):0 - PMID: 29436902 - PMCID: PMC5955442 - DOI: 10.1080/21505594.2018.1438025

Jin L, Engelhart AE, Adamala KP, Szostak JW

Preparation, Purification, and Use of Fatty Acid-containing Liposomes.
J Vis Exp. 2018;(132):ePub - PMID: 29553563 - PMCID: PMC5912384 - DOI: 10.3791/57324

Wellington S, Hung DT

The expanding diversity of Mycobacterium tuberculosis drug targets.
ACS Infect Dis. 2018;4(5):696-714 - PMID: 29412643 - DOI: 10.1021/acsinfecdis.7b00255

Zhang W, Tam CP, Zhou L, Oh SS, Wang J, Szostak JW

A structural rationale for the enhanced catalysis of nonenzymatic RNA primer extension by a downstream oligonucleotide.
J Am Chem Soc. 2018;140(8):2829-2840 - PMID: 29411978 - PMCID: PMC6326529 - DOI: 10.1021/jacs.7b11750

Mohanan V, Nakata T, Desch AN, Lévesque C, Boroughs A, Guzman G, Cao Z, Creasey E, Yao J, Boucher G, Charron G, Bhan AK, Schenone M, Carr SA, Reinecker HC, Daly MJ, Rioux JD, Lassen KG, Xavier RJ

C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.
Science. 2018;359(6380):1161-1166 - PMID: 29420262 - PMCID: PMC6008784 - DOI: 10.1126/science.aan0814

Smillie CS, Sauk J, Gevers D, Friedman J, Sung J, Youngster I, Hohmann EL, Staley C, Khoruts A, Sadowsky MJ, Allegretti JR, Smith MB, Xavier RJ, Alm EJ

Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation.
Cell Host Microbe. 2018;23(2):229-240.e5 - PMID: 29447696 - PMCID: PMC8318347 - DOI: 10.1016/j.chom.2018.01.003

Smillie CS, Sauk J, Gevers D, Friedman J, Sung J, Youngster I, Hohmann EL, Staley C, Khoruts A, Sadowsky MJ, Allegretti JR, Smith MB, Xavier RJ, Alm EJ

Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation.
Cell Host Microbe. 2018;23(2):229-240.e5 - PMID: 29447696 - PMCID: PMC8318347 - DOI: 10.1016/j.chom.2018.01.003

Kolde R, Franzosa EA, Rahnavard G, Hall AB, Vlamakis H, Stevens C, Daly MJ, Xavier RJ, Huttenhower C

Host genetic variation and its microbiome interactions within the Human Microbiome Project.
Genome Med. 2018;10(1):6 - PMID: 29378630 - PMCID: PMC5789541 - DOI: 10.1186/s13073-018-0515-8

Luther J, Gala M, Patel SJ, Dave M, Borren N, Xavier RJ, Ananthakrishnan AN

Loss of Response to Anti-Tumor Necrosis Factor Alpha Therapy in Crohn's Disease Is Not Associated with Emergence of Novel Inflammatory Pathways.
Dig Dis Sci. 2018;63(3):738-745 - PMID: 29372477 - PMCID: PMC6152907 - DOI: 10.1007/s10620-018-4932-8

Datta S, Seed B

Influence of multiplicative stochastic variation on translational elongation rates.
PLoS One. 2018;13(1):e0191152 - PMID: 29351322 - PMCID: PMC5774726 - DOI: 10.1371/journal.pone.0191152

Visschedijk MC, Spekhorst LM, Cheng SC, van Loo ES, Jansen BHD, Blokzijl T, Kil H, de Jong DJ, Pierik M, Maljaars JPWJ, van der Woude CJ, van Bodegraven AA, Oldenburg B, Löwenberg M, Nieuwenhuijs VB, Imhann F, van Sommeren S, Alberts R, Xavier RJ, Dijkstra G, Faber KN, Aldaz CM, Weersma RK, Festen EAM

Genomic and expression analyses identify a disease modifying variant for fibrostenotic Crohn's disease.
J Crohns Colitis. 2018;12(5):582-588 - PMID: 29361163 - DOI: 10.1093/ecco-jcc/jjy001
Total: 2489