The Center for Computational and Integrative Biology is an affiliation of faculty drawn together by a common interest in the study of biology through methods engaging a broader scale of inquiry than the existing standard of the era. The faculty collectively has highly diverse interests, ranging from inquiries into the origins of life, the mechanisms of host-pathogen interactions in plants and model organisms, the relationship between atherosclerosis and inflammatory responses in vertebrates, and the collection and analysis of comprehensive measures of physiology in an attempt to understand the harbingers of adverse outcomes (principally sepsis and its sequelae) in individuals treated for trauma.
The Center for Computational and Integrative Biology provides support for investigators at the hospital and across Boston through a variety of autonomous cores that provide services in DNA sequencing, oligonucleotide synthesis and research laboratory automation.
CCIB in the News
CCIB Awards & Honors
Fred Ausubel: William Silen Lifetime Achievement Excellence in Mentoring Award
Fred Ausubel has been named the recipient of the 2014-2015 William Silen Lifetime Achievement Award at HMS. This award was established to recognize the value of quality mentoring relationships and the impact they have on professional development and career advancement in basic/clinical medicine, research, teaching, and administration. Additional information is available here
Dr. Ausubel is a Professor of Genetics at Harvard Medical School and the Ernst Winnacker Distinguished Investigator in the Department of Molecular Biology at Massachusetts General Hospital. He was elected to the National Academy of Sciences in 1994, the American Academy of Microbiology in 2002, and the American Academy of Arts and Sciences in 2003. In addition to serving on a variety of editorial boards, Dr. Ausubel is founding editor of the widely-read Current Protocols in Molecular Biology.
Ramnik Xavier: Center for Microbiome Informatics and Therapeutics
MGH and MIT have announced a new strategic partnership in microbiome research to be led by Ramnik Xavier, Chief of the Division of Gastroenterology at MGH and a founding member of CCIB, and Eric Alm, an associate professor of biological engineering at MIT. Named the Center for Microbiome Informatics and Therapeutics , the center is designed to advance the science of the human microbiome, and the treatment of conditions and diseases associated with an altered microbiome. The center’s main functions are to fund cross-disciplinary and innovative research proposals, to provide shared services for researchers studying the microbiome, and to build an interactive academic community of clinicians and academic researchers interested in tackling microbiome-related disease. Initial projects will focus on the role of the microbiome in inflammatory bowel disease, with future plans to explore the role of the microbiome in other systemic autoimmune diseases, including autism, MS, arthritis, diabetes, and allergies.
Gary Ruvkun: 2015 Breakthrough Prize in Life Sciences
Gary Ruvkun was awarded the 2015 Breakthrough Prize for his role in the discovery of micro-RNA molecules, along with Victor Ambros of the University of Massachusetts Medical School.
Gary is a Professor of Genetics at Harvard Medical School, Molecular Biologist at Massachusetts General Hospital and member of the National Academy of Sciences, the Institute of Medicine and the American Academy of Arts and Sciences. Previous honors and awards include the Rosenstiel Award from Brandeis University (with Victor Ambros, Andy Fire, and Craig Mello), the Warren Triennial Prize from Massachusetts General Hospital (with Victor Ambros), the Benjamin Franklin Medal from the Franklin Institute (with Victor Ambros and David Baulcombe), the Gairdner International Award from the Gairdner Foundation of Canada (with Victor Ambros), the Albert Lasker Award for Basic Medical Research (with Victor Ambros and David Baulcombe), the Louisa Horwitz Prize from Columbia University (with Victor Ambros), the Shaul and Meira Massry Prize (with Victor Ambros), the Dan David Prize for Aging research (with Cynthia Kenyon), the Ipsen Foundation Longevity Prize, the 2014 Wolf Prize (with Victor Ambros) and the 2014 Gruber Genetics Prize (with Victor Ambros).
Additional information is found here