• Efron PA, Darden DB, Wang Z, Nacionales DC, Lopez MC, Hawkins RB, Cox MC, Rincon JC, Ungaro R, Dirain ML, Ghita GL, Chen T, Billiar TR, Delano MJ, Leeuwenburgh C, Bihorac A, Brakenridge SC, Moore FA, Mohr AM, Tompkins RG, Brumback BA, Baker HV, Upchurch GR, Moldawer LL Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis. FASEB J. 2021;35(2):e21156 - PMID: 33140449 - PMCID: PMC7855423 - DOI: 10.1096/fj.202002150R

  • Tsurumi A, Flaherty PJ, Que YA, Ryan CM, Mendoza AE, Almpani M, Bandyopadhaya A, Ogura A, Dhole YV, Goodfield LF, Tompkins RG, Rahme LG Multi-biomarker Prediction Models for Multiple Infection Episodes Following Blunt Trauma. iScience. 2020;23(11):101659 - PMID: 33047099 - PMCID: PMC7539926 - DOI: 10.1016/j.isci.2020.101659

  • Frydman GH, Tessier SN, Wong KHK, Vanderburg CR, Fox JG, Toner M, Tompkins RG, Irimia D Megakaryocytes contain extranuclear histones and may be a source of platelet-associated histones during sepsis. Sci Rep. 2020;10(1):4621 - PMID: 32165642 - PMCID: PMC7067782 - DOI: 10.1038/s41598-020-61309-3

  • Brady KJS, Ni P, Grant GG, Thorpe CR, Nadler D, Lee A, Shapiro G, Kogosov A, Palmieri TL, Tompkins RG, Schneider JC, Kazis LE, Ryan CM Translation and Cross-Cultural Validation of the English Young Adult Burn Outcome Questionnaire (YABOQ) in Spanish. J Burn Care Res. 2020;41(3):640-646 - PMID: 31930334 - DOI: 10.1093/jbcr/iraa011

  • Dreckmann SC, Amini-Nik S, Tompkins RG, Vojvodic M, Jeschke MG Genome-wide comparisons of gene expression in adult versus elderly burn patients. PLoS One. 2019;14(12):e0226425 - PMID: 31834907 - PMCID: PMC6910697 - DOI: 10.1371/journal.pone.0226425

  • Ogura A, Tsurumi A, Que YA, Almpani M, Zheng H, Tompkins RG, Ryan CM, Rahme LG Associations between clinical characteristics and the development of multiple organ failure after severe burns in adult patients. Burns. 2019;45(8):1775-1782 - PMID: 31690472 - DOI: 10.1016/j.burns.2019.02.014

  • Elmaleh DR, Farlow MR, Conti PS, Tompkins RG, Kundakovic L, Tanzi RE Developing Effective Alzheimer's Disease Therapies: Clinical Experience and Future Directions. J Alzheimers Dis. 2019;71(3):715-732 - PMID: 31476157 - PMCID: PMC6839593 - DOI: 10.3233/JAD-190507

  • Nakazawa H, Ikeda K, Shinozaki S, Yasuhara S, Yu YM, Martyn JAJ, Tompkins RG, Yorozu T, Inoue S, Kaneki M Coenzyme Q10 protects against burn-induced mitochondrial dysfunction and impaired insulin signaling in mouse skeletal muscle. FEBS Open Bio. 2019;9(2):348-363 - PMID: 30761259 - PMCID: PMC6356165 - DOI: 10.1002/2211-5463.12580

  • Nakazawa H, Ikeda K, Shinozaki S, Kobayashi M, Ikegami Y, Fu M, Nakamura T, Yasuhara S, Yu YM, Martyn JAJ, Tompkins RG, Shimokado K, Yorozu T, Ito H, Inoue S, Kaneki M Burn-induced muscle metabolic derangements and mitochondrial dysfunction are associated with activation of HIF-1α and mTORC1: Role of protein farnesylation. Sci Rep. 2017;7(1):6618 - PMID: 28747716 - PMCID: PMC5529411 - DOI: 10.1038/s41598-017-07011-3

  • Frydman GH, Metcalf Pate KA, Marini RP, de Laforcade AM, Bosch I, Bakthavatchalu V, Muthupalani S, Swennes AG, Lyons CE, Tompkins RG, Fox JG Adult-onset, chronic, cyclic thrombocytopenia in a Rhesus macaque (Macaca mulatta) after dengue virus vaccination and viral challenge. Vet Clin Pathol. 2017;46(2):238-247 - PMID: 28518476 - PMCID: PMC5977396 - DOI: 10.1111/vcp.12497

  • Khan MA, Khan MF, Kashiwagi S, Kem WR, Yasuhara S, Kaneki M, Tompkins RG, Martyn JA An Alpha7 Nicotinic Acetylcholine Receptor Agonist (GTS-21) Promotes C2C12 Myonuclear Accretion in Association with Release of Interleukin-6 (IL-6) and Improves Survival in Burned Mice. Shock. 2017;48(2):227-235 - PMID: 28282360 - PMCID: PMC5511057 - DOI: 10.1097/SHK.0000000000000849

  • Frydman GH, Marini RP, Bakthavatchalu V, Biddle KE, Muthupalani S, Vanderburg CR, Lai B, Bendapudi PK, Tompkins RG, Fox JG Local and Systemic Changes Associated with Long-term, Percutaneous, Static Implantation of Titanium Alloys in Rhesus Macaques (Macaca mulatta). Comp Med. 2017;67(2):165-175 - PMID: 28381317 - PMCID: PMC5402736

  • Nakazawa H, Chang K, Shinozaki S, Yasukawa T, Ishimaru K, Yasuhara S, Yu YM, Martyn JA, Tompkins RG, Shimokado K, Kaneki M iNOS as a Driver of Inflammation and Apoptosis in Mouse Skeletal Muscle after Burn Injury: Possible Involvement of Sirt1 S-Nitrosylation-Mediated Acetylation of p65 NF-?B and p53. PLoS One. 2017;12(1):e0170391 - PMID: 28099528 - PMCID: PMC5242494 - DOI: 10.1371/journal.pone.0170391

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  • Li P, Tompkins RG, Xiao W, KERIS: kaleidoscope of gene responses to inflammation between species. Nucleic Acids Res. 2017;45(D1):D908-D914 - PMID: 27789704 - PMCID: PMC5210651 - DOI: 10.1093/nar/gkw974

  • Tsurumi A, Que YA, Ryan CM, Tompkins RG, Rahme LG TNF-?/IL-10 Ratio Correlates with Burn Severity and May Serve as a Risk Predictor of Increased Susceptibility to Infections. Front Public Health. 2016;4:216 - PMID: 27761434 - PMCID: PMC5050217 - DOI: 10.3389/fpubh.2016.00216

  • Porter C, Tompkins RG, Finnerty CC, Sidossis LS, Suman OE, Herndon DN The metabolic stress response to burn trauma: current understanding and therapies. Lancet. 2016;388(10052):1417-1426 - PMID: 27707498 - PMCID: PMC5753602 - DOI: 10.1016/S0140-6736(16)31469-6

  • Frydman GH, Le A, Ellett F, Jorgensen J, Fox JG, Tompkins RG, Irimia D Changes in neutrophil migration patterns upon contact with platelets in a microfluidic assay. J Leukoc Biol. 2017;101(3):797-806 - PMID: 27630219 - PMCID: PMC5295852 - DOI: 10.1189/jlb.1TA1115-517RR

  • Kashiwagi S, Khan MA, Yasuhara S, Goto T, Tompkins RG, Kaneki M, Martyn JA Prevention of Burn-Induced Inflammatory Responses and Muscle Wasting By GTS-21, A Specific Agonist for ?7 Nicotinic Acetylcholine Receptors. Shock. 2017;47(1):61-69 - PMID: 27529131 - PMCID: PMC5167674 - DOI: 10.1097/SHK.0000000000000729

  • Syrkina O, Hales CH, Bonab AA, Hamrahi V, Paul K, Jung WJ, Tompkins RG, Fischman AJ, Carter EA Molecular Imaging of Smoke-Induced Changes in Nuclear Factor-Kappa B Expression in Murine Tissues Including the Lung. J Burn Care Res. 2016;37(6):335-342 - PMID: 27437954 - DOI: 10.1097/BCR.0000000000000394

  • Frydman GH, Bendapudi PK, Marini RP, Vanderburg CR, Tompkins RG, Fox JG Coagulation Biomarkers in Healthy Chinese-Origin Rhesus Macaques (Macaca mulatta). J Am Assoc Lab Anim Sci. 2016;55(3):252-9 - PMID: 27177557 - PMCID: PMC4865685

  • Ueki R, Liu L, Kashiwagi S, Kaneki M, Khan M, Hirose M, Tompkins RG, Martyn JA, Yasuhara S Role of Elevated Fibrinogen in Burn-Induced Mitochondrial Dysfunction: Protective Effects of Glycyrrhizin. Shock. 2016;46(4):382-9 - PMID: 27172157 - PMCID: PMC5026541 - DOI: 10.1097/SHK.0000000000000602

  • Kazis LE, Lee AF, Rose M, Liang MH, Li NC, Ren XS, Sheridan R, Gilroy-Lewis J, Stoddard F, Hinson M, Warden G, Stubbs K, Blakeney P, Meyer W, McCauley R, Herndon D, Palmieri T, Mooney K, Wood D, Pidcock F, Reilly D, Cullen M, Calvert C, Ryan CM, Schneider JC, Soley-Bori M, Tompkins RG Recovery Curves for Pediatric Burn Survivors: Advances in Patient-Oriented Outcomes. JAMA Pediatr. 2016;170(6):534-42 - PMID: 26953515 - DOI: 10.1001/jamapediatrics.2015.4722

  • Ryan CM, Cartwright S, Schneider JC, Tompkins RG, Kazis LE The burn outcome questionnaires: Patient and family reported outcome metrics for children of all ages. Burns. 2016;42(5):1144-1145 - PMID: 26803370 - DOI: 10.1016/j.burns.2015.10.033

  • Mason SA, Nathens AB, Finnerty CC, Gamelli RL, Gibran NS, Arnoldo BD, Tompkins RG, Herndon DN, Jeschke MG, Hold the Pendulum: Rates of Acute Kidney Injury are Increased in Patients Who Receive Resuscitation Volumes Less than Predicted by the Parkland Equation. Ann Surg. 2016;:ePub - PMID: 26764868

  • Constantinou C, Apidianakis Y, Psychogios N, Righi V, Mindrinos MN, Khan N, Swartz HM, Szeto HH, Tompkins RG, Rahme LG, Tzika AA In vivo high-resolution magic angle spinning magnetic and electron paramagnetic resonance spectroscopic analysis of mitochondria-targeted peptide in Drosophila melanogaster with trauma-induced thoracic injury. Int J Mol Med. 2016;37(2):299-308 - PMID: 26648055 - PMCID: PMC4716799 - DOI: 10.3892/ijmm.2015.2426

  • Lee AF, Ryan CM, Schneider JC, Kazis LE, Li NC, Rose M, Liang MH, Wang C, Palmieri T, Meyer WJ, Pidcock FS, Reilly D, Sheridan RL, Tompkins RG, Quantifying Risk Factors for Long-Term Sleep Problems After Burn Injury in Young Adults. J Burn Care Res. 2015;38(2):e510-e520 - PMID: 27003738 - DOI: 10.1097/BCR.0000000000000315

  • Sood RF, Gibran NS, Arnoldo BD, Gamelli RL, Herndon DN, Tompkins RG, Inflammation T, Investigators TH Early Leukocyte Gene Expression Associated with Age, Burn Size, and Inhalation Injury in Severely Burned Adults. J Trauma Acute Care Surg. 2016;80(2):250-7 - PMID: 26517785 - PMCID: PMC4731271 - DOI: 10.1097/TA.0000000000000905

  • Inoue Y, Yu YM, Kurihara T, Vasilyev A, Ibrahim A, Oklu R, Zhao G, Nair AV, Brown D, Fischman AJ, Tompkins RG, Irimia D Kidney and Liver Injuries After Major Burns in Rats Are Prevented by Resolvin D2. Crit Care Med. 2016;44(5):e241-52 - PMID: 26509319 - PMCID: PMC4833510 - DOI: 10.1097/CCM.0000000000001397

  • Orr SK, Butler KL, Hayden D, Tompkins RG, Serhan CN, Irimia D Gene Expression of Proresolving Lipid Mediator Pathways Is Associated With Clinical Outcomes in Trauma Patients. Crit Care Med. 2015;43(12):2642-2650 - PMID: 26488221 - PMCID: PMC4651815 - DOI: 10.1097/CCM.0000000000001312

  • Ryan CM, Lee AF, Kazis LE, Shapiro GD, Schneider JC, Goverman J, Fagan SP, Wang C, Kim J, Sheridan RL, Tompkins RG Is Real-Time Feedback of Burn-Specific Patient-Reported Outcome Measures in Clinical Settings Practical and Useful? A Pilot Study Implementing the Young Adult Burn Outcome Questionnaire. J Burn Care Res. 2015;37(1):64-74 - PMID: 26284638 - DOI: 10.1097/BCR.0000000000000287

  • Tsurumi A, Que YA, Yan S, Tompkins RG, Rahme LG, Ryan CM Do standard burn mortality formulae work on a population of severely burned children and adults?. Burns. 2015;41(5):935-45 - PMID: 25922299 - DOI: 10.1016/j.burns.2015.03.017

  • Tompkins RG Genomics of injury: The Glue Grant experience. J Trauma Acute Care Surg. 2015;78(4):671-686 - PMID: 25742245 - PMCID: PMC4389222 - DOI: 10.1097/TA.0000000000000568

  • Nakazawa H, Yamada M, Tanaka T, Kramer J, Yu YM, Fischman AJ, Martyn JA, Tompkins RG, Kaneki M Role of Protein Farnesylation in Burn-Induced Metabolic Derangements and Insulin Resistance in Mouse Skeletal Muscle. PLoS One. 2015;10(1):e0116633 - PMID: 25594415 - PMCID: PMC4296934 - DOI: 10.1371/journal.pone.0116633

  • Jeschke MG, Pinto R, Kraft R, Nathens AB, Finnerty CC, Gamelli RL, Gibran NS, Klein MB, Arnoldo BD, Tompkins RG, Herndon DN, Morbidity and Survival Probability in Burn Patients in Modern Burn Care. Crit Care Med. 2015;43(4):808-15 - PMID: 25559438 - PMCID: PMC4359665 - DOI: 10.1097/CCM.0000000000000790

  • Warren HS, Tompkins RG, Moldawer LL, Seok J, Xu W, Mindrinos MN, Maier RV, Xiao W, Davis RW Mice are not men. Proc Natl Acad Sci U S A. 2015;112(4):E345 - PMID: 25540422 - PMCID: PMC4313842 - DOI: 10.1073/pnas.1414857111

  • Ryan CM, Lee A, Kazis LE, Schneider JC, Shapiro GD, Sheridan RL, Meyer WJ, Palmieri T, Pidcock FS, Reilly D, Tompkins RG, Recovery Trajectories After Burn Injury in Young Adults: Does Burn Size Matter?. J Burn Care Res. 2014;36(1):118-29 - PMID: 25501787 - DOI: 10.1097/BCR.0000000000000214

  • Jones CN, Moore M, Dimisko L, Alexander A, Ibrahim A, Hassell BA, Warren HS, Tompkins RG, Fagan SP, Irimia D Spontaneous Neutrophil Migration Patterns during Sepsis after Major Burns. PLoS One. 2014;9(12):e114509 - PMID: 25489947 - PMCID: PMC4260850 - DOI: 10.1371/journal.pone.0114509

  • Carter EA, Paul K, Bonab AA, Tompkins RG, Fischman AJ Effect of exercise on burn-induced changes in tissue-specific glucose metabolism. J Burn Care Res. 2014;35(6):470-3 - PMID: 24476988 - PMCID: PMC4113562 - DOI: 10.1097/BCR.0000000000000036

  • Kotz KT, Petrofsky AC, Haghgooie R, Granier R, Toner M, Tompkins RG Inertial focusing cytometer with integrated optics for particle characterization. Technology (Singap World Sci). 2014;1(1):27-36 - PMID: 25346940 - PMCID: PMC4206911 - DOI: 10.1142/S233954781350009X

  • Peterson JR, De La Rosa S, Eboda O, Cilwa KE, Agarwal S, Buchman SR, Cederna PS, Xi C, Morris MD, Herndon DN, Xiao W, Tompkins RG, Krebsbach PH, Wang SC, Levi B Treatment of heterotopic ossification through remote ATP hydrolysis. Sci Transl Med. 2014;6(255):255ra132 - PMID: 25253675 - PMCID: PMC4353731 - DOI: 10.1126/scitranslmed.3008810

  • Carter EA, Hamrahi V, Paul K, Bonab AA, Jung W, Tompkins RG, Fischman AJ Single Hind Limb Burn Injury to Mice Alters Nuclear Factor-?B Expression and [18F] 2-Fluoro-2-Deoxy-D-Glucose Uptake. J Burn Care Res. 2014;35(6):e373-e378 - PMID: 25100541 - PMCID: PMC4229441 - DOI: 10.1097/BCR.0000000000000035

  • Zhao G, Yu YM, Kaneki M, Bonab AA, Tompkins RG, Fischman AJ Simvastatin Reduces Burn Injury-Induced Splenic Apoptosis via Downregulation of the TNF-?/NF-?B Pathway. Ann Surg. 2015;261(5):1006-12 - PMID: 24950285 - PMCID: PMC4272342 - DOI: 10.1097/SLA.0000000000000764

  • Yan S, Tsurumi A, Que YA, Ryan CM, Bandyopadhaya A, Morgan AA, Flaherty PJ, Tompkins RG, Rahme LG Prediction of Multiple Infections After Severe Burn Trauma: A Prospective Cohort Study. Ann Surg. 2015;261(4):781-792 - PMID: 24950278 - PMCID: PMC4284150 - DOI: 10.1097/SLA.0000000000000759

  • Wolf SE, Tompkins RG, Herndon DN On the Horizon: Research Priorities in Burns for the Next Decade. Surg Clin North Am. 2014;94(4):917-30 - PMID: 25085097 - DOI: 10.1016/j.suc.2014.05.012

  • Ryu SY, Qian WJ, Camp DG, Smith RD, Tompkins RG, Davis RW, Xiao W Detecting differential protein expression in large-scale population proteomics. Bioinformatics. 2014;30(19):2741-6 - PMID: 24928210 - PMCID: PMC4173009 - DOI: 10.1093/bioinformatics/btu341

  • Klein MB, Goverman J, Hayden DL, Fagan SP, McDonald-Smith GP, Alexander AK, Gamelli RL, Gibran NS, Finnerty CC, Jeschke MG, Arnoldo B, Wispelwey B, Mindrinos MN, Xiao W, Honari SE, Mason PH, Schoenfeld DA, Herndon DN, Tompkins RG, Benchmarking outcomes in the critically injured burn patient. Ann Surg. 2014;259(5):833-41 - PMID: 24722222 - PMCID: PMC4283803 - DOI: 10.1097/SLA.0000000000000438

  • Righi V, Apidianakis Y, Psychogios N, Rahme LG, Tompkins RG, Tzika AA In vivo high-resolution magic angle spinning proton NMR spectroscopy of Drosophila melanogaster flies as a model system to investigate mitochondrial dysfunction in Drosophila GST2 mutants. Int J Mol Med. 2014;34(1):327-33 - PMID: 24789699 - DOI: 10.3892/ijmm.2014.1757

  • Tompkins RG Survival From Burns in the New Millennium: 70 Years' Experience From a Single Institution. Ann Surg. 2015;261(2):263-268 - PMID: 24670865 - PMCID: PMC4372065 - DOI: 10.1097/SLA.0000000000000623

  • Sheridan RL, Stoddard FJ, Kazis LE, Lee A, Li NC, Kagan RJ, Palmieri TL, Meyer WJ, Nicolai M, Stubbs TK, Chan G, Hinson MI, Herndon DN, Tompkins RG, Long-term posttraumatic stress symptoms vary inversely with early opiate dosing in children recovering from serious burns: Effects durable at 4 years. J Trauma Acute Care Surg. 2014;76(3):828-32 - PMID: 24553556 - DOI: 10.1097/TA.0b013e3182ab111c

  • Zhao G, Yu YM, Shoup TM, Elmaleh DR, Bonab AA, Tompkins RG, Fischman AJ Membrane potential-dependent uptake of (18)F-triphenylphosphonium-a new voltage sensor as an imaging agent for detecting burn-induced apoptosis. J Surg Res. 2014;188(2):473-9 - PMID: 24582214 - PMCID: PMC3988254 - DOI: 10.1016/j.jss.2014.01.011

  • Tzika AA, Constantinou C, Bandyopadhaya A, Psychogios N, Lee S, Mindrinos M, Martyn JA, Tompkins RG, Rahme LG A Small Volatile Bacterial Molecule Triggers Mitochondrial Dysfunction in Murine Skeletal Muscle. PLoS One. 2013;8(9):e74528 - PMID: 24098655 - PMCID: PMC3787027 - DOI: 10.1371/journal.pone.0074528

  • Tompkins RG, Warren HS, Mindrinos MN, Xiao W, Davis RW Reply to Osterburg et al.: To study human inflammatory diseases in humans. Proc Natl Acad Sci U S A. 2013;110(36):E3371 - PMID: 24137798 - PMCID: PMC3767510 - DOI: 10.1073/pnas.1307452110

  • Rae L, Pham TN, Carrougher G, Honari S, Gibran NS, Arnoldo BD, Gamelli RL, Tompkins RG, Herndon DN Differences in Resuscitation in Morbidly Obese Burn Patients May Contribute to High Mortality. J Burn Care Res. 2013;34(5):507-14 - PMID: 23966116 - PMCID: PMC3800202 - DOI: 10.1097/BCR.0b013e3182a2a771

  • Warren HS, Tompkins RG, Mindrinos MN, Xiao W, Davis RW Reply to Cauwels et al.: Of men, not mice, and inflammation. Proc Natl Acad Sci U S A. 2013;110(34):E3151 - PMID: 24137663 - PMCID: PMC3752239 - DOI: 10.1073/pnas.1308943110

  • Jeschke MG, Finnerty CC, Emdad F, Rivero HG, Kraft R, Williams FN, Gamelli RL, Gibran NS, Klein MB, Arnoldo BD, Tompkins RG, Herndon DN Mild Obesity Is Protective After Severe Burn Injury. Ann Surg. 2013;258(6):1119-29 - PMID: 23877367 - PMCID: PMC3963145 - DOI: 10.1097/SLA.0b013e3182984d19

  • Ryan CM, Schneider JC, Kazis LE, Lee A, Li NC, Hinson M, Bauk H, Peck M, Meyer WJ, Palmieri T, Pidcock FS, Reilly D, Tompkins RG, Benchmarks for Multidimensional Recovery After Burn Injury in Young Adults: The Development, Validation, and Testing of the American Burn Association/Shriners Hospitals for Children Young Adult Burn Outcome Questionnaire. J Burn Care Res. 2013;34(3):e121-42 - PMID: 23511284 - DOI: 10.1097/BCR.0b013e31827e7ecf

  • Zhou JY, Krovvidi RK, Gao Y, Gao H, Petritis BO, De A, Miller-Graziano C, Bankey PE, Petyuk VA, Nicora CD, Clauss TR, Moore RJ, Shi T, Brown JN, Kaushal A, Xiao W, Davis RW, Maier RV, Tompkins RG, Qian WJ, Camp DG, Smith RD, Trauma-associated Human Neutrophil Alterations Revealed by Comparative Proteomics Profiling. Proteomics Clin Appl. 2013;7(7-8):571-83 - PMID: 23589343 - PMCID: PMC3737403 - DOI: 10.1002/prca.201200109

  • Righi V, Constantinou C, Mintzopoulos D, Khan N, Mupparaju SP, Rahme LG, Swartz HM, Szeto HH, Tompkins RG, Tzika AA Mitochondria-targeted antioxidant promotes recovery of skeletal muscle mitochondrial function after burn trauma assessed by in vivo 31P nuclear magnetic resonance and electron paramagnetic resonance spectroscopy. FASEB J. 2013;27(6):2521-30 - PMID: 23482635 - PMCID: PMC3659352 - DOI: 10.1096/fj.12-220764

  • Hosokawa S, Nagashima M, Maeyama Y, Koseki H, Yomogida K, Mehr C, Rutledge M, Greenfeld H, Kaneki M, Tompkins RG, Martyn JJ, Yasuhara SE Efficacy of Phosphodiesterase 5 inhibitor on distant burn-induced muscle autophagy, microcirculation and survival rate. Am J Physiol Endocrinol Metab. 2013;304(9):E922-33 - PMID: 23512808 - DOI: 10.1152/ajpendo.00078.2013

  • Watada S, Yu YM, Fischman AJ, Kurihara T, Shen CA, Tompkins RG, Fagan S Evaluation of Intragastric Vs Intraperitoneal Glucose Tolerance Tests in the Evaluation of Insulin Resistance in a Rodent Model of Burn Injury and Glucagon-Like Polypeptide-1 Treatment. J Burn Care Res. 2013;35(1):e66-72 - PMID: 23511296 - PMCID: PMC4053788 - DOI: 10.1097/BCR.0b013e31828a8ede

  • Finnerty CC, Jeschke MG, Qian WJ, Kaushal A, Xiao W, Liu T, Gritsenko MA, Moore RJ, Camp DG, Moldawer LL, Elson C, Schoenfeld D, Gamelli R, Gibran N, Klein M, Arnoldo B, Remick D, Smith RD, Davis R, Tompkins RG, Herndon DN, Determination of Burn Patient Outcome by Large-Scale Quantitative Discovery Proteomics. Crit Care Med. 2013;41(6):1421-1434 - PMID: 23507713 - PMCID: PMC3660437 - DOI: 10.1097/CCM.0b013e31827c072e

  • Kurihara T, Jones CN, Yu YM, Fischman AJ, Watada S, Tompkins RG, Fagan SP, Irimia D Resolvin D2 restores neutrophil directionality and improves survival after burns. FASEB J. 2013;27(6):2270-81 - PMID: 23430978 - PMCID: PMC3659356 - DOI: 10.1096/fj.12-219519

  • Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Jeschke MG, Klein MB, Gamelli RL, Gibran NS, Brownstein BH, Miller-Graziano C, Calvano SE, Mason PH, Cobb JP, Rahme LG, Lowry SF, Maier RV, Moldawer LL, Herndon DN, Davis RW, Xiao W, Tompkins RG, Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A. 2013;110(9):3507-12 - PMID: 23401516 - PMCID: PMC3587220 - DOI: 10.1073/pnas.1222878110

  • Cuenca AG, Gentile LF, Lopez MC, Ungaro R, Liu H, Xiao W, Seok J, Mindrinos MN, Ang D, Ozrazgat Baslanti T, Bihorac A, Efron PA, Cuschieri J, Warren HS, Tompkins RG, Maier RV, Baker HV, Moldawer LL, Development of a Genomic Metric That Can Be Rapidly Used to Predict Clinical Outcome in Severely Injured Trauma Patients. Crit Care Med. 2013;41(5):1175-1185 - PMID: 23388514 - PMCID: PMC3652285 - DOI: 10.1097/CCM.0b013e318277131c

  • Lu XM, Tompkins R, Fischman A Burn injury-induced IRS-1 degradation in mouse skeletal muscle. Int J Burns Trauma. 2013;3(1):37-48 - PMID: 23386984 - PMCID: PMC3560490

  • Lu XM, Tompkins RG, Fischman AJ Nitric oxide activates intradomain disulfide bond formation in the kinase loop of Akt1/PKB? after burn injury. Int J Mol Med. 2013;31(3):740-50 - PMID: 23314241 - PMCID: PMC3597556 - DOI: 10.3892/ijmm.2013.1241

  • Zhao G, Yu YM, Kaneki M, Tompkins RG, Fischman AJ Simvastatin Protects Hepatocytes From Apoptosis by Suppressing the TNF-?/Caspase-3 Signaling Pathway in Mice With Burn Injury. Ann Surg. 2013;257(6):1129-36 - PMID: 23275311 - PMCID: PMC4102342 - DOI: 10.1097/SLA.0b013e318273fdca

  • Yo K, Yu YM, Zhao G, Bonab AA, Aikawa N, Tompkins RG, Fischman AJ Brown Adipose Tissue and Its Modulation by a Mitochondria-targeted Peptide in Rat Burn Injury Induced Hypermetabolism. Am J Physiol Endocrinol Metab. 2013;304(4):E331-41 - PMID: 23169784 - PMCID: PMC3566510 - DOI: 10.1152/ajpendo.00098.2012

  • Carter EA, Winter D, Tolman C, Paul K, Hamrahi V, Tompkins RG, Fischman AJ Combination of Radiation and Burn Injury Alters [18F] 2-Fluoro-2-Deoxy-D-Glucose Uptake in Mice. J Burn Care Res. 2012;33(6):723-30 - PMID: 23143615 - PMCID: PMC3673011 - DOI: 10.1097/BCR.0b013e31825d678f

  • Papagiannaros A, Righi V, Day GG, Rahme LG, Liu PK, Fischman AJ, Tompkins RG, Tzika AA Imaging C-Fos Gene Expression in Burns Using Lipid Coated Spion Nanoparticles. Adv J Mol Imaging. 2012;2(4):31-37 - PMID: 24995147 - PMCID: PMC4076698 - DOI: 10.4236/ami.2012.24005

  • Carey K, Kazis LE, Lee AF, Liang MH, Li NC, Hinson MI, Lydon MK, Bauk H, Shapiro GD, Tompkins RG, Measuring the cost of care for children with acute burn injury. J Trauma Acute Care Surg. 2012;73(3 Suppl 2):S229-33 - PMID: 22929551 - DOI: 10.1097/TA.0b013e318265c88a

  • Palmieri TL, Nelson-Mooney K, Kagan RJ, Stubbs TK, Meyer WJ, Herndon DN, Hinson MI, Lee AF, Li NC, Kazis LE, Tompkins RG, Impact of hand burns on health-related quality of life in children younger than 5 years. J Trauma Acute Care Surg. 2012;73(3 Suppl 2):S197-204 - PMID: 22929547 - DOI: 10.1097/TA.0b013e318265c7ff

  • Tompkins RG, Liang MH, Lee AF, Kazis LE, The American Burn Association/Shriners Hospitals for Children Burn Outcomes Program: A progress report at 15 years. J Trauma Acute Care Surg. 2012;73(3 Suppl 2):S173-8 - PMID: 22929544 - DOI: 10.1097/TA.0b013e318265c53e

  • Carter EA, Paul KW, Barrow SA, Fischman AJ, Tompkins RG Previous burn injury predisposes mice to lipopolysaccharide-induced changes in glucose metabolism. J Burn Care Res. 2012;33(5):683-9 - PMID: 22961012 - PMCID: PMC3441057 - DOI: 10.1097/BCR.0b013e31825d6a86

  • Hamrahi V, Hamblin MR, Jung W, Benjamin JB, Paul KW, Fischman AJ, Tompkins RG, Carter EA Gram-Negative Bacterial Infection in Thigh Abscess Can Migrate to Distant Burn Depending on Burn Depth. Interdiscip Perspect Infect Dis. 2012;2012:567140 - PMID: 22899912 - PMCID: PMC3412104 - DOI: 10.1155/2012/567140

  • Hamrahi VF, Goverman J, Jung W, Wu JC, Fischman AJ, Tompkins RG, Yu YY, Fagan SP, Carter EA In vivo molecular imaging of murine embryonic stem cells delivered to a burn wound surface via Integra® scaffolding. J Burn Care Res. 2012;33(2):e49-54 - PMID: 22540138 - PMCID: PMC3311992 - DOI: 10.1097/BCR.0b013e3182331d1c

  • Minei JP, Cuschieri J, Sperry J, Moore EE, West MA, Harbrecht BG, O'Keefe GE, Cohen MJ, Moldawer LL, Tompkins RG, Maier RV The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock*. Crit Care Med. 2012;40(4):1129-1135 - PMID: 22020243 - PMCID: PMC3343366 - DOI: 10.1097/CCM.0b013e3182376e9f

  • Cuschieri J, Johnson JL, Sperry J, West MA, Moore EE, Minei JP, Bankey PE, Nathens AB, Cuenca AG, Efron PA, Hennessy L, Xiao W, Mindrinos MN, McDonald-Smith GP, Mason PH, Billiar TR, Schoenfeld DA, Warren HS, Cobb JP, Moldawer LL, Davis RW, Maier RV, Tompkins RG, Benchmarking Outcomes in the Critically Injured Trauma Patient and the Effect of Implementing Standard Operating Procedures. Ann Surg. 2012;255(5):993-9 - PMID: 22470077 - PMCID: PMC3327791 - DOI: 10.1097/SLA.0b013e31824f1ebc

  • Hipp J, Monaco J, Kunju LP, Cheng J, Yagi Y, Rodriguez-Canales J, Emmert-Buck MR, Hewitt S, Feldman MD, Tomaszewski JE, Toner M, Tompkins RG, Flotte T, Lucas D, Gilbertson JR, Madabhushi A, Balis U Integration of architectural and cytologic driven image algorithms for prostate adenocarcinoma identification. Anal Cell Pathol (Amst). 2012;35(4):251-65 - PMID: 22425661 - PMCID: PMC4605585 - DOI: 10.3233/ACP-2012-0054

  • Hamrahi VF, Goverman J, Jung W, Wu JC, Fischman AJ, Tompkins RG, Yu YY, Fagan SP, Carter EA In Vivo Molecular Imaging of Murine Embryonic Stem Cells Delivered to a Burn Wound Surface via Integra® Scaffolding. J Burn Care Res. 2012;33(2):e49-54 - PMID: 22441149 - PMCID: PMC3311992

  • Jeschke MG, Finnerty CC, Herndon DN, Song J, Boehning D, Tompkins RG, Baker HV, Gauglitz GG Severe injury is associated with insulin resistance, endoplasmic reticulum stress response, and unfolded protein response. Ann Surg. 2012;255(2):370-8 - PMID: 22241293 - PMCID: PMC3395076 - DOI: 10.1097/SLA.0b013e31823e76e7

  • Tompkins RG Survival of children with burn injuries. Lancet. 2012;379(9820):983-4 - PMID: 22296811 - PMCID: PMC4019221 - DOI: 10.1016/S0140-6736(11)61626-7

  • Song J, Finnerty CC, Herndon DN, Kraft R, Boehning D, Brooks NC, Tompkins RG, Jeschke MG Thermal Injury Activates eEF2k-Dependent eEF2 Pathway in Pediatric Patients. JPEN J Parenter Enteral Nutr. 2012;36(5):596-602 - PMID: 22269896 - PMCID: PMC3580832 - DOI: 10.1177/0148607111422234

  • Weber JM, Sheridan RL, Fagan S, Ryan CM, Pasternack MS, Tompkins RG Incidence of Catheter-Associated Bloodstream Infection After Introduction of Minocycline and Rifampin Antimicrobial-Coated Catheters in a Pediatric Burn Population. J Burn Care Res. 2012;33(4):539-43 - PMID: 22210071 - DOI: 10.1097/BCR.0b013e31823c4cd5

  • Lee HY, Kaneki M, Andreas J, Tompkins RG, Martyn JA Novel mitochondria-targeted antioxidant peptide ameliorates burn-induced apoptosis and endoplasmic reticulum stress in the skeletal muscle of mice. Shock. 2011;36(6):580-5 - PMID: 21937949 - PMCID: PMC3230221 - DOI: 10.1097/SHK.0b013e3182366872

  • Xiao W, Mindrinos MN, Seok J, Cuschieri J, Cuenca AG, Gao H, Hayden DL, Hennessy L, Moore EE, Minei JP, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Brownstein BH, Mason PH, Baker HV, Finnerty CC, Jeschke MG, López MC, Klein MB, Gamelli RL, Gibran NS, Arnoldo B, Xu W, Zhang Y, Calvano SE, McDonald-Smith GP, Schoenfeld DA, Storey JD, Cobb JP, Warren HS, Moldawer LL, Herndon DN, Lowry SF, Maier RV, Davis RW, Tompkins RG, A genomic storm in critically injured humans. J Exp Med. 2011;208(13):2581-90 - PMID: 22110166 - PMCID: PMC3244029 - DOI: 10.1084/jem.20111354

  • Warner EA, Kotz KT, Ungaro RF, Abouhamze AS, Lopez MC, Cuenca AG, Kelly-Scumpia KM, Moreno C, O'Malley KA, Lanz JD, Baker HV, Martin LC, Toner M, Tompkins RG, Efron PA, Moldawer LL Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage. Lab Invest. 2011;91(12):1787-95 - PMID: 21931299 - PMCID: PMC3957199 - DOI: 10.1038/labinvest.2011.94

  • Desai KH, Tan CS, Leek JT, Maier RV, Tompkins RG, Storey JD, Dissecting inflammatory complications in critically injured patients by within-patient gene expression changes: a longitudinal clinical genomics study. PLoS Med. 2011;8(9):e1001093 - PMID: 21931541 - PMCID: PMC3172280 - DOI: 10.1371/journal.pmed.1001093

  • Carter EA, Bonab AA, Paul K, Yerxa J, Tompkins RG, Fischman AJ Association of heat production with 18F-FDG accumulation in murine brown adipose tissue after stress. J Nucl Med. 2011;52(10):1616-20 - PMID: 21914754 - PMCID: PMC4082963 - DOI: 10.2967/jnumed.111.090175

  • Stoddard FJ, White GW, Kazis LE, Murphy JM, Sorrentino EA, Hinson M, Kim Stubbs T, Chan G, Sheridan RL, Palmieri T, Kagan R, Herndon D, Tompkins RG Patterns of medication administration from 2001 to 2009 in the treatment of children with acute burn injuries: a multicenter study. J Burn Care Res. 2011;32(5):519-28 - PMID: 21811176 - DOI: 10.1097/BCR.0b013e31822bef92

  • Ryan CM, Antoon A, Fagan SP, Goverman J, Lawlor D, Sheridan RL, Tompkins RG Considerations for preparedness for a pediatric burn disaster. J Burn Care Res. 2011;32(5):e165-6 - PMID: 21772149 - DOI: 10.1097/BCR.0b013e31822ac9a4

  • Cuenca AG, Maier RV, Cuschieri J, Moore EE, Moldawer LL, Tompkins RG, The Glue Grant experience: characterizing the post injury genomic response. Eur J Trauma Emerg Surg. 2011;37(6):549-58 - PMID: 26815465 - PMCID: PMC6541206 - DOI: 10.1007/s00068-011-0148-8

  • Yang W, Yamada M, Tamura Y, Chang K, Mao J, Zou L, Feng Y, Kida K, Scherrer-Crosbie M, Chao W, Ichinose F, Yu YM, Fischman AJ, Tompkins RG, Yao S, Kaneki M Farnesyltransferase inhibitor FTI-277 reduces mortality of septic mice along with improved bacterial clearance. J Pharmacol Exp Ther. 2011;339(3):832-41 - PMID: 21873557 - PMCID: PMC3226365 - DOI: 10.1124/jpet.111.183558

  • Carter EA, Bonab AA, Goverman J, Paul K, Yerxa J, Tompkins RG, Fischman AJ Evaluation of the antioxidant peptide SS31 for treatment of burn-induced insulin resistance. Int J Mol Med. 2011;28(4):589-94 - PMID: 21805045 - PMCID: PMC4090514 - DOI: 10.3892/ijmm.2011.752

  • Hipp J, Flotte T, Monaco J, Cheng J, Madabhushi A, Yagi Y, Rodriguez-Canales J, Emmert-Buck M, Dugan MC, Hewitt S, Toner M, Tompkins RG, Lucas D, Gilbertson JR, Balis UJ Computer aided diagnostic tools aim to empower rather than replace pathologists: Lessons learned from computational chess. J Pathol Inform. 2011;2:25 - PMID: 21773056 - PMCID: PMC3132993 - DOI: 10.4103/2153-3539.82050

  • Carter EA, Bonab AA, Hamrahi V, Pitman J, Winter D, Macintosh LJ, Cyr EM, Paul K, Yerxa J, Jung W, Tompkins RG, Fischman AJ Effects of burn injury, cold stress and cutaneous wound injury on the morphology and energy metabolism of murine brown adipose tissue (BAT) in vivo. Life Sci. 2011;89(3-4):78-85 - PMID: 21565200 - PMCID: PMC4081480 - DOI: 10.1016/j.lfs.2011.04.014

  • Berthiaume F, Tompkins RG, Yarmush ML Isolation and long-term maintenance of adult rat hepatocytes in culture. Methods Mol Med. 2011;18:447-56 - PMID: 21370195 - DOI: 10.1385/0-89603-516-6:447

  • Hipp JD, Cheng JY, Toner M, Tompkins RG, Balis UJ Spatially Invariant Vector Quantization: A pattern matching algorithm for multiple classes of image subject matter including pathology. J Pathol Inform. 2011;2:13 - PMID: 21383936 - PMCID: PMC3049270 - DOI: 10.4103/2153-3539.77175

  • Xu W, Seok J, Mindrinos MN, Schweitzer AC, Jiang H, Wilhelmy J, Clark TA, Kapur K, Xing Y, Faham M, Storey JD, Moldawer LL, Maier RV, Tompkins RG, Wong WH, Davis RW, Xiao W, Human transcriptome array for high-throughput clinical studies. Proc Natl Acad Sci U S A. 2011;108(9):3707-12 - PMID: 21317363 - PMCID: PMC3048146 - DOI: 10.1073/pnas.1019753108

  • Shen CA, Fagan S, Fischman AJ, Carter EE, Chai JK, Lu XM, Yu YM, Tompkins RG Effects of glucagon-like peptide 1 on glycemia control and its metabolic consequence after severe thermal injury--studies in an animal model. Surgery. 2011;149(5):635-44 - PMID: 21295809 - PMCID: PMC3079016 - DOI: 10.1016/j.surg.2010.11.017

  • Rosenbach AE, Koria P, Goverman J, Kotz KT, Gupta A, Yu M, Fagan SP, Irimia D, Tompkins RG Microfluidics for T- lymphocyte cell separation and inflammation monitoring in burn patients. Clin Transl Sci. 2011;4(1):63-8 - PMID: 21348958 - PMCID: PMC3057059 - DOI: 10.1111/j.1752-8062.2010.00255.x

  • Mosier MJ, Pham TN, Klein MB, Gibran NS, Arnoldo BD, Gamelli RL, Tompkins RG, Herndon DN Early enteral nutrition in burns: compliance with guidelines and associated outcomes in a multicenter study. J Burn Care Res. 2011;32(1):104-9 - PMID: 21116188 - PMCID: PMC3850279 - DOI: 10.1097/BCR.0b013e318204b3be

  • Prelack K, Yu YM, Dylewski M, Lydon M, Sheridan RL, Tompkins RG The contribution of muscle to whole-body protein turnover throughout the course of burn injury in children. J Burn Care Res. 2010;31(6):942-8 - PMID: 21105320 - PMCID: PMC4084779 - DOI: 10.1097/BCR.0b013e3181f938e1

  • Butler KL, Goverman J, Ma H, Fischman A, Yu YM, Bilodeau M, Rad AM, Bonab AA, Tompkins RG, Fagan SP Stem cells and burns: review and therapeutic implications. J Burn Care Res. 2010;31(6):874-81 - PMID: 20859216 - DOI: 10.1097/BCR.0b013e3181f9353a

  • Qian WJ, Petritis BO, Kaushal A, Finnerty CC, Jeschke MG, Monroe ME, Moore RJ, Schepmoes AA, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, Smith RD, Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomics. J Proteome Res. 2010;9(9):4779-89 - PMID: 20698492 - PMCID: PMC2945297 - DOI: 10.1021/pr1005026

  • Bonab AA, Carter EA, Paul K, Kaneki M, Yu YM, Tompkins RG, Fischman AJ Effect of simvastatin on burn-induced alterations in tissue specific glucose metabolism: implications for burn associated insulin resistance. Int J Mol Med. 2010;26(3):311-6 - PMID: 20664945 - PMCID: PMC4090513

  • Kotz KT, Xiao W, Miller-Graziano C, Qian WJ, Russom A, Warner EA, Moldawer LL, De A, Bankey PE, Petritis BO, Camp DG, Rosenbach AE, Goverman J, Fagan SP, Brownstein BH, Irimia D, Xu W, Wilhelmy J, Mindrinos MN, Smith RD, Davis RW, Tompkins RG, Toner M, Clinical microfluidics for neutrophil genomics and proteomics. Nat Med. 2010;16(9):1042-7 - PMID: 20802500 - PMCID: PMC3136804 - DOI: 10.1038/nm.2205

  • Butler KL, Ambravaneswaran V, Agrawal N, Bilodeau M, Toner M, Tompkins RG, Fagan S, Irimia D Burn injury reduces neutrophil directional migration speed in microfluidic devices. PLoS One. 2010;5(7):e11921 - PMID: 20689600 - PMCID: PMC2912851 - DOI: 10.1371/journal.pone.0011921

  • Yagi H, Soto-Gutierrez A, Navarro-Alvarez N, Nahmias Y, Goldwasser Y, Kitagawa Y, Tilles AW, Tompkins RG, Parekkadan B, Yarmush ML Reactive bone marrow stromal cells attenuate systemic inflammation via sTNFR1. Mol Ther. 2010;18(10):1857-64 - PMID: 20664529 - PMCID: PMC2951565 - DOI: 10.1038/mt.2010.155

  • Yagi H, Soto-Gutierrez A, Kitagawa Y, Tilles AW, Tompkins RG, Yarmush ML Bone marrow mesenchymal stromal cells attenuate organ injury induced by LPS and burn. Cell Transplant. 2010;19(6):823-30 - PMID: 20573305 - PMCID: PMC2957544 - DOI: 10.3727/096368910X508942

  • Yagi H, Soto-Gutierrez A, Parekkadan B, Kitagawa Y, Tompkins RG, Kobayashi N, Yarmush ML Mesenchymal stem cells: Mechanisms of immunomodulation and homing. Cell Transplant. 2010;19(6):667-79 - PMID: 20525442 - PMCID: PMC2957533 - DOI: 10.3727/096368910X508762

  • Stott SL, Lee RJ, Nagrath S, Yu M, Miyamoto DT, Ulkus L, Inserra EJ, Ulman M, Springer S, Nakamura Z, Moore AL, Tsukrov DI, Kempner ME, Dahl DM, Wu CL, Iafrate AJ, Smith MR, Tompkins RG, Sequist LV, Toner M, Haber DA, Maheswaran S Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer. Sci Transl Med. 2010;2(25):25ra23 - PMID: 20424012 - PMCID: PMC3141292 - DOI: 10.1126/scitranslmed.3000403

  • Mosier MJ, Pham TN, Klein MB, Gibran NS, Arnoldo BD, Gamelli RL, Tompkins RG, Herndon DN Early acute kidney injury predicts progressive renal dysfunction and higher mortality in severely burned adults. J Burn Care Res. 2010;31(1):83-92 - PMID: 20061841 - PMCID: PMC3045668 - DOI: 10.1097/BCR.0b013e3181cb8c87

  • Yagi H, Parekkadan B, Suganuma K, Soto-Gutierrez A, Tompkins RG, Tilles AW, Yarmush ML Long-term superior performance of a stem cell/hepatocyte device for the treatment of acute liver failure. Tissue Eng Part A. 2009;15(11):3377-88 - PMID: 19397469 - PMCID: PMC2792056 - DOI: 10.1089/ten.TEA.2008.0681

  • Cobb JP, Moore EE, Hayden DL, Minei JP, Cuschieri J, Yang J, Li Q, Lin N, Brownstein BH, Hennessy L, Mason PH, Schierding WS, Dixon DJ, Tompkins RG, Warren HS, Schoenfeld DA, Maier RV Validation of the riboleukogram to detect ventilator-associated pneumonia after severe injury. Ann Surg. 2009;250(4):531-9 - PMID: 19730236 - PMCID: PMC3047595 - DOI: 10.1097/SLA.0b013e3181b8fbd5

  • Lu XM, Hamrahi VF, Tompkins RG, Fischman AJ Effect of insulin levels on the phosphorylation of specific amino acid residues in IRS-1: implications for burn-induced insulin resistance. Int J Mol Med. 2009;24(4):531-8 - PMID: 19724894 - PMCID: PMC4084762 - DOI: 10.3892/ijmm_00000262

  • Stoddard FJ, Sorrentino EA, Ceranoglu TA, Saxe G, Murphy JM, Drake JE, Ronfeldt H, White GW, Kagan J, Snidman N, Sheridan RL, Tompkins RG Preliminary evidence for the effects of morphine on posttraumatic stress disorder symptoms in one- to four-year-olds with burns. J Burn Care Res. 2009;30(5):836-43 - PMID: 19692914 - DOI: 10.1097/BCR.0b013e3181b48102

  • Tzika AA, Mintzopoulos D, Mindrinos M, Zhang J, Rahme LG, Tompkins RG Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle. Int J Mol Med. 2009;24(3):387-92 - PMID: 19639232 - PMCID: PMC3207251 - DOI: 10.3892/ijmm_00000244

  • Warren HS, Elson CM, Hayden DL, Schoenfeld DA, Cobb JP, Maier RV, Moldawer LL, Moore EE, Harbrecht BG, Pelak K, Cuschieri J, Herndon DN, Jeschke MG, Finnerty CC, Brownstein BH, Hennessy L, Mason PH, Tompkins RG, A genomic score prognostic of outcome in trauma patients. Mol Med. 2009;15(7-8):220-7 - PMID: 19593405 - PMCID: PMC2707513 - DOI: 10.2119/molmed.2009.00027

  • Yin HN, Chai JK, Yu YM, Shen CA, Wu YQ, Yao YM, Liu H, Liang LM, Tompkins RG, Sheng ZY Regulation of signaling pathways downstream of IGF-I/insulin by androgen in skeletal muscle of glucocorticoid-treated rats. J Trauma. 2009;66(4):1083-90 - PMID: 19359918 - PMCID: PMC4085982 - DOI: 10.1097/TA.0b013e31817e7420

  • Cheng X, Gupta A, Chen C, Tompkins RG, Rodriguez W, Toner M Enhancing the performance of a point-of-care CD4+ T-cell counting microchip through monocyte depletion for HIV/AIDS diagnostics. Lab Chip. 2009;9(10):1357-64 - PMID: 19417901 - PMCID: PMC4064257 - DOI: 10.1039/b818813k

  • Neely AN, Gardner J, Durkee P, Warden GD, Greenhalgh DG, Gallagher JJ, Herndon DN, Tompkins RG, Kagan RJ Are topical antimicrobials effective against bacteria that are highly resistant to systemic antibiotics?. J Burn Care Res. 2009;30(1):19-29 - PMID: 19060725 - DOI: 10.1097/BCR.0b013e3181921eed

  • Qian WJ, Liu T, Petyuk VA, Gritsenko MA, Petritis BO, Polpitiya AD, Kaushal A, Xiao W, Finnerty CC, Jeschke MG, Jaitly N, Monroe ME, Moore RJ, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, Smith RD, Large-scale multiplexed quantitative discovery proteomics enabled by the use of an (18)O-labeled "universal" reference sample. J Proteome Res. 2009;8(1):290-9 - PMID: 19053531 - PMCID: PMC2752204 - DOI: 10.1021/pr800467r

  • Pham TN, Klein MB, Gibran NS, Arnoldo BD, Gamelli RL, Silver GM, Jeschke MG, Finnerty CC, Tompkins RG, Herndon DN Impact of oxandrolone treatment on acute outcomes after severe burn injury. J Burn Care Res. 2008;29(6):902-6 - PMID: 18849836 - PMCID: PMC3958934 - DOI: 10.1097/BCR.0b013e31818ba14d

  • Huang R, Barber TA, Schmidt MA, Tompkins RG, Toner M, Bianchi DW, Kapur R, Flejter WL A microfluidics approach for the isolation of nucleated red blood cells (NRBCs) from the peripheral blood of pregnant women. Prenat Diagn. 2008;28(10):892-9 - PMID: 18821715 - PMCID: PMC4482103 - DOI: 10.1002/pd.2079

  • Finnerty CC, Jeschke MG, Herndon DN, Gamelli R, Gibran N, Klein M, Silver G, Arnoldo B, Remick D, Tompkins RG, Temporal cytokine profiles in severely burned patients: a comparison of adults and children. Mol Med. 2008;14(9-10):553-60 - PMID: 18548133 - PMCID: PMC2424320 - DOI: 10.2119/2007-00132.Finnerty

  • Maheswaran S, Sequist LV, Nagrath S, Ulkus L, Brannigan B, Collura CV, Inserra E, Diederichs S, Iafrate AJ, Bell DW, Digumarthy S, Muzikansky A, Irimia D, Settleman J, Tompkins RG, Lynch TJ, Toner M, Haber DA Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med. 2008;359(4):366-77 - PMID: 18596266 - PMCID: PMC3551471 - DOI: 10.1056/NEJMoa0800668

  • Sena MJ, Utter GH, Cuschieri J, Maier RV, Tompkins RG, Harbrecht BG, Moore EE, O'Keefe GE Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients. J Am Coll Surg. 2008;207(4):459-67 - PMID: 18926446 - PMCID: PMC4002002 - DOI: 10.1016/j.jamcollsurg.2008.04.028

  • Tzika AA, Astrakas LG, Cao H, Mintzopoulos D, Zhang Q, Padfield K, Yu H, Mindrinos MN, Rahme LG, Tompkins RG Murine intramyocellular lipids quantified by NMR act as metabolic biomarkers in burn trauma. Int J Mol Med. 2008;21(6):825-32 - PMID: 18506378

  • Cabral CB, Bullock KH, Bischoff DJ, Tompkins RG, Yu YM, Kelleher JK Estimating glutathione synthesis with deuterated water: a model for peptide biosynthesis. Anal Biochem. 2008;379(1):40-4 - PMID: 18486587 - PMCID: PMC4065382 - DOI: 10.1016/j.ab.2008.04.042

  • Zhang Q, Ma B, Fischman AJ, Tompkins RG, Carter EA Increased uncoupling protein 1 mRNA expression in mice brown adipose tissue after burn injury. J Burn Care Res. 2008;29(2):358-62 - PMID: 18354294 - DOI: 10.1097/BCR.0b013e318166739c

  • Zhang Q, Carter EA, Ma B, Fischman AJ, Tompkins RG Burn-related metabolic and signaling changes in rat brain. J Burn Care Res. 2008;29(2):346-52 - PMID: 18354292 - DOI: 10.1097/BCR.0b013e3181667387

  • Russom A, Sethu P, Irimia D, Mindrinos MN, Calvano SE, Garcia I, Finnerty C, Tannahill C, Abouhamze A, Wilhelmy J, López MC, Baker HV, Herndon DN, Lowry SF, Maier RV, Davis RW, Moldawer LL, Tompkins RG, Toner M, Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients. Clin Chem. 2008;54(5):891-900 - PMID: 18375483 - PMCID: PMC4011019 - DOI: 10.1373/clinchem.2007.099150

  • Di Carlo D, Edd JF, Irimia D, Tompkins RG, Toner M Equilibrium separation and filtration of particles using differential inertial focusing. Anal Chem. 2008;80(6):2204-11 - PMID: 18275222 - DOI: 10.1021/ac702283m

  • Toner M, Tompkins RG Invention, innovation, entrepreneurship in academic medical centers. Surgery. 2008;143(2):168-71 - PMID: 18242329 - PMCID: PMC2408552 - DOI: 10.1016/j.surg.2007.11.004

  • Tzika AA, Mintzopoulos D, Padfield K, Wilhelmy J, Mindrinos MN, Yu H, Cao H, Zhang Q, Astrakas LG, Zhang J, Yu YM, Rahme LG, Tompkins RG Reduced rate of adenosine triphosphate synthesis by in vivo 31P nuclear magnetic resonance spectroscopy and downregulation of PGC-1beta in distal skeletal muscle following burn. Int J Mol Med. 2008;21(2):201-8 - PMID: 18204786

  • Apidianakis Y, Mindrinos MN, Xiao W, Tegos GP, Papisov MI, Hamblin MR, Davis RW, Tompkins RG, Rahme LG Involvement of skeletal muscle gene regulatory network in susceptibility to wound infection following trauma. PLoS One. 2007;2(12):e1356 - PMID: 18159239 - PMCID: PMC2131783 - DOI: 10.1371/journal.pone.0001356

  • Greenhalgh DG, Saffle JR, Holmes JH, Gamelli RL, Palmieri TL, Horton JW, Tompkins RG, Traber DL, Mozingo DW, Deitch EA, Goodwin CW, Herndon DN, Gallagher JJ, Sanford AP, Jeng JC, Ahrenholz DH, Neely AN, O'Mara MS, Wolf SE, Purdue GF, Garner WL, Yowler CJ, Latenser BA, American Burn Association consensus conference to define sepsis and infection in burns. J Burn Care Res. 2007;28(6):776-90 - PMID: 17925660 - DOI: 10.1097/BCR.0b013e3181599bc9

  • Nagrath S, Sequist LV, Maheswaran S, Bell DW, Irimia D, Ulkus L, Smith MR, Kwak EL, Digumarthy S, Muzikansky A, Ryan P, Balis UJ, Tompkins RG, Haber DA, Toner M Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature. 2007;450(7173):1235-9 - PMID: 18097410 - PMCID: PMC3090667 - DOI: 10.1038/nature06385

  • Di Carlo D, Irimia D, Tompkins RG, Toner M Continuous inertial focusing, ordering, and separation of particles in microchannels. Proc Natl Acad Sci U S A. 2007;104(48):18892-7 - PMID: 18025477 - PMCID: PMC2141878 - DOI: 10.1073/pnas.0704958104

  • Murakami K, Enkhbaatar P, Yu YM, Traber LD, Cox RA, Hawkins HK, Tompkins RG, Herndon D, Traber DL L-arginine attenuates acute lung injury after smoke inhalation and burn injury in sheep. Shock. 2007;28(4):477-83 - PMID: 17558346 - DOI: 10.1097/shk.0b013e31804a59bd

  • Lesic B, Lépine F, Déziel E, Zhang J, Zhang Q, Padfield K, Castonguay MH, Milot S, Stachel S, Tzika AA, Tompkins RG, Rahme LG Inhibitors of pathogen intercellular signals as selective anti-infective compounds. PLoS Pathog. 2007;3(9):1229-39 - PMID: 17941706 - PMCID: PMC2323289 - DOI: 10.1371/journal.ppat.0030126

  • Cheng X, Irimia D, Dixon M, Ziperstein JC, Demirci U, Zamir L, Tompkins RG, Toner M, Rodriguez WR A microchip approach for practical label-free CD4+ T-cell counting of HIV-infected subjects in resource-poor settings. J Acquir Immune Defic Syndr. 2007;45(3):257-61 - PMID: 17414933 - DOI: 10.1097/QAI.0b013e3180500303

  • Klein MB, Hayden D, Elson C, Nathens AB, Gamelli RL, Gibran NS, Herndon DN, Arnoldo B, Silver G, Schoenfeld D, Tompkins RG The association between fluid administration and outcome following major burn: a multicenter study. Ann Surg. 2007;245(4):622-8 - PMID: 17414612 - PMCID: PMC1877030 - DOI: 10.1097/01.sla.0000252572.50684.49

  • Silver GM, Klein MB, Herndon DN, Gamelli RL, Gibran NS, Altstein L, McDonald-Smith GP, Tompkins RG, Hunt JL, Standard operating procedures for the clinical management of patients enrolled in a prospective study of Inflammation and the Host Response to Thermal Injury. J Burn Care Res. 2007;28(2):222-30 - PMID: 17351437 - DOI: 10.1097/BCR.0B013E318031AA44

  • Nathens AB, McMurray MK, Cuschieri J, Durr EA, Moore EE, Bankey PE, Freeman B, Harbrecht BG, Johnson JL, Minei JP, McKinley BA, Moore FA, Shapiro MB, West MA, Tompkins RG, Maier RV The practice of venous thromboembolism prophylaxis in the major trauma patient. J Trauma. 2007;62(3):557-62; discussion 562-3 - PMID: 17414328 - DOI: 10.1097/TA.0b013e318031b5f5

  • Zhang Q, Cao H, Astrakas LG, Mintzopoulos D, Mindrinos MN, Schulz J, Tompkins RG, Rahme LG, Tzika AA Uncoupling protein 3 expression and intramyocellular lipid accumulation by NMR following local burn trauma. Int J Mol Med. 2006;18(6):1223-9 - PMID: 17089030

  • Laudanski K, Miller-Graziano C, Xiao W, Mindrinos MN, Richards DR, De A, Moldawer LL, Maier RV, Bankey P, Baker HV, Brownstein BH, Cobb JP, Calvano SE, Davis RW, Tompkins RG Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways. Proc Natl Acad Sci U S A. 2006;103(42):15564-9 - PMID: 17032758 - PMCID: PMC1592643 - DOI: 10.1073/pnas.0607028103

  • Padfield KE, Zhang Q, Gopalan S, Tzika AA, Mindrinos MN, Tompkins RG, Rahme LG Local and distant burn injury alter immuno-inflammatory gene expression in skeletal muscle. J Trauma. 2006;61(2):280-92 - PMID: 16917440 - DOI: 10.1097/01.ta.0000230567.56797.6c

  • Sethu P, Moldawer LL, Mindrinos MN, Scumpia PO, Tannahill CL, Wilhelmy J, Efron PA, Brownstein BH, Tompkins RG, Toner M Microfluidic isolation of leukocytes from whole blood for phenotype and gene expression analysis. Anal Chem. 2006;78(15):5453-61 - PMID: 16878882 - DOI: 10.1021/ac060140c

  • Klein MB, Silver G, Gamelli RL, Gibran NS, Herndon DN, Hunt JL, Tompkins RG, Inflammation and the host response to injury: an overview of the multicenter study of the genomic and proteomic response to burn injury. J Burn Care Res. 2006;27(4):448-51 - PMID: 16819346 - DOI: 10.1097/01.BCR.0000227477.33877.E6

  • Sekine K, Revzin A, Tompkins RG, Toner M Panning of multiple subsets of leukocytes on antibody-decorated poly(ethylene) glycol-coated glass slides. J Immunol Methods. 2006;313(1-2):96-109 - PMID: 16822521 - DOI: 10.1016/j.jim.2006.03.017

  • Liu T, Qian WJ, Gritsenko MA, Xiao W, Moldawer LL, Kaushal A, Monroe ME, Varnum SM, Moore RJ, Purvine SO, Maier RV, Davis RW, Tompkins RG, Camp DG, Smith RD, High dynamic range characterization of the trauma patient plasma proteome. Mol Cell Proteomics. 2006;5(10):1899-913 - PMID: 16684767 - PMCID: PMC1783978 - DOI: 10.1074/mcp.M600068-MCP200

  • Yasuhara S, Kaneki M, Sugita H, Sugita M, Asai A, Sahani N, Chon JY, Tompkins RG, Martyn JA Adipocyte apoptosis after burn injury is associated with altered fat metabolism. J Burn Care Res. 2006;27(3):367-76 - PMID: 16679908 - DOI: 10.1097/01.BCR.0000216777.94365.47

  • Beffa DC, Carter EA, Lu XM, Yu YM, Prelack K, Sheridan RL, Young VR, Fischman AJ, Tompkins RG Negative chemical ionization gas chromatography/mass spectrometry to quantify urinary 3-methylhistidine: application to burn injury. Anal Biochem. 2006;355(1):95-101 - PMID: 16762308 - DOI: 10.1016/j.ab.2006.03.057

  • Shinoda M, Tilles AW, Wakabayashi G, Takayanagi A, Harada H, Obara H, Suganuma K, Berthiaume F, Shimazu M, Shimizu N, Kitajima M, Tompkins RG, Toner M, Yarmush ML Treatment of fulminant hepatic failure in rats using a bioartificial liver device containing porcine hepatocytes producing interleukin-1 receptor antagonist. Tissue Eng. 2006;12(5):1313-23 - PMID: 16771644 - PMCID: PMC3202215 - DOI: 10.1089/ten.2006.12.1313

  • Sugimachi K, Roach KL, Rhoads DB, Tompkins RG, Toner M Nonmetabolizable glucose compounds impart cryotolerance to primary rat hepatocytes. Tissue Eng. 2006;12(3):579-88 - PMID: 16579691 - DOI: 10.1089/ten.2006.12.579

  • De AK, Miller-Graziano CL, Calvano SE, Laudanski K, Lowry SF, Moldawer LL, Remick DG, Rajicic N, Schoenfeld D, Tompkins RG Selective activation of peripheral blood T cell subsets by endotoxin infusion in healthy human subjects corresponds to differential chemokine activation. J Immunol. 2005;175(9):6155-62 - PMID: 16237112 - DOI: 10.4049/jimmunol.175.9.6155

  • Storey JD, Xiao W, Leek JT, Tompkins RG, Davis RW Significance analysis of time course microarray experiments. Proc Natl Acad Sci U S A. 2005;102(36):12837-42 - PMID: 16141318 - PMCID: PMC1201697 - DOI: 10.1073/pnas.0504609102

  • Lu XM, Lu M, Tompkins RG, Fischman AJ Site-specific detection of S-nitrosylated PKB alpha/Akt1 from rat soleus muscle using CapLC-Q-TOF(micro) mass spectrometry. J Mass Spectrom. 2005;40(9):1140-8 - PMID: 16041729 - DOI: 10.1002/jms.885

  • Sin A, Murthy SK, Revzin A, Tompkins RG, Toner M Enrichment using antibody-coated microfluidic chambers in shear flow: model mixtures of human lymphocytes. Biotechnol Bioeng. 2005;91(7):816-26 - PMID: 16037988 - DOI: 10.1002/bit.20556

  • Astrakas LG, Goljer I, Yasuhara S, Padfield KE, Zhang Q, Gopalan S, Mindrinos MN, Dai G, Yu YM, Martyn JA, Tompkins RG, Rahme LG, Tzika AA Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma-induced apoptosis. FASEB J. 2005;19(11):1431-40 - PMID: 16126910 - DOI: 10.1096/fj.04-2005com

  • Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho RJ, Chen RO, Brownstein BH, Cobb JP, Tschoeke SK, Miller-Graziano C, Moldawer LL, Mindrinos MN, Davis RW, Tompkins RG, Lowry SF, A network-based analysis of systemic inflammation in humans. Nature. 2005;437(7061):1032-7 - PMID: 16136080 - DOI: 10.1038/nature03985

  • Zhang Q, Carter EA, Ma BY, White M, Fischman AJ, Tompkins RG Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation. Life Sci. 2005;77(24):3068-77 - PMID: 15982669 - DOI: 10.1016/j.lfs.2005.02.034

  • Lu XM, Lu MY, Fischman AJ, Tompkins RG A new approach for sequencing human IRS1 phosphotyrosine-containing peptides using CapLC-Q-TOF(micro). J Mass Spectrom. 2005;40(5):599-607 - PMID: 15739155 - DOI: 10.1002/jms.826

  • Padfield KE, Astrakas LG, Zhang Q, Gopalan S, Dai G, Mindrinos MN, Tompkins RG, Rahme LG, Tzika AA Burn injury causes mitochondrial dysfunction in skeletal muscle. Proc Natl Acad Sci U S A. 2005;102(15):5368-73 - PMID: 15809440 - PMCID: PMC556259 - DOI: 10.1073/pnas.0501211102

  • Cobb JP, Mindrinos MN, Miller-Graziano C, Calvano SE, Baker HV, Xiao W, Laudanski K, Brownstein BH, Elson CM, Hayden DL, Herndon DN, Lowry SF, Maier RV, Schoenfeld DA, Moldawer LL, Davis RW, Tompkins RG, Baker HV, Bankey P, Billiar T, Brownstein BH, Calvano SE, Camp D, Chaudry I, Cobb JP, Davis RW, Elson CM, Freeman B, Gamelli R, Gibran N, Harbrecht B, Hayden DL, Heagy W, Heimbach D, Herndon DN, Horton J, Hunt J, Laudanski K, Lederer J, Lowry SF, Maier RV, Mannick J, McKinley B, Miller-Graziano C, Mindrinos MN, Minei J, Moldawer LL, Moore E, Moore F, Munford R, Nathens A, O'keefe G, Purdue G, Rahme L, Remick D, Sailors M, Schoenfeld DA, Shapiro M, Silver G, Smith R, Stephanopoulos G, Stormo G, Tompkins RG, Toner M, Warren S, West M, Wolfe S, Xiao W, Young V, Application of genome-wide expression analysis to human health and disease. Proc Natl Acad Sci U S A. 2005;102(13):4801-6 - PMID: 15781863 - PMCID: PMC555033 - DOI: 10.1073/pnas.0409768102

  • Qian WJ, Monroe ME, Liu T, Jacobs JM, Anderson GA, Shen Y, Moore RJ, Anderson DJ, Zhang R, Calvano SE, Lowry SF, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Camp DG, Smith RD, Quantitative proteome analysis of human plasma following in vivo lipopolysaccharide administration using 16O/18O labeling and the accurate mass and time tag approach. Mol Cell Proteomics. 2005;4(5):700-9 - PMID: 15753121 - PMCID: PMC1829297 - DOI: 10.1074/mcp.M500045-MCP200

  • Yokoyama T, Banta S, Berthiaume F, Nagrath D, Tompkins RG, Yarmush ML Evolution of intrahepatic carbon, nitrogen, and energy metabolism in a D-galactosamine-induced rat liver failure model. Metab Eng. 2005;7(2):88-103 - PMID: 15781418 - DOI: 10.1016/j.ymben.2004.09.003

  • Qian WJ, Jacobs JM, Camp DG, Monroe ME, Moore RJ, Gritsenko MA, Calvano SE, Lowry SF, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Smith RD Comparative proteome analyses of human plasma following in vivo lipopolysaccharide administration using multidimensional separations coupled with tandem mass spectrometry. Proteomics. 2005;5(2):572-84 - PMID: 15627965 - PMCID: PMC1781926 - DOI: 10.1002/pmic.200400942

  • Sosef MN, Baust JM, Sugimachi K, Fowler A, Tompkins RG, Toner M Cryopreservation of isolated primary rat hepatocytes: enhanced survival and long-term hepatospecific function. Ann Surg. 2005;241(1):125-33 - PMID: 15622000 - PMCID: PMC1356855 - DOI: 10.1097/01.sla.0000149303.48692.0f

  • Murthy SK, Sin A, Tompkins RG, Toner M Effect of flow and surface conditions on human lymphocyte isolation using microfluidic chambers. Langmuir. 2004;20(26):11649-55 - PMID: 15595794 - DOI: 10.1021/la048047b

  • Sethu P, Anahtar M, Moldawer LL, Tompkins RG, Toner M Continuous flow microfluidic device for rapid erythrocyte lysis. Anal Chem. 2004;76(21):6247-53 - PMID: 15516115 - DOI: 10.1021/ac049429p

  • Feezor RJ, Baker HV, Mindrinos M, Hayden D, Tannahill CL, Brownstein BH, Fay A, MacMillan S, Laramie J, Xiao W, Moldawer LL, Cobb JP, Laudanski K, Miller-Graziano CL, Maier RV, Schoenfeld D, Davis RW, Tompkins RG, Whole blood and leukocyte RNA isolation for gene expression analyses. Physiol Genomics. 2004;19(3):247-54 - PMID: 15548831 - DOI: 10.1152/physiolgenomics.00020.2004

  • Irimia D, Tompkins RG, Toner M Single-cell chemical lysis in picoliter-scale closed volumes using a microfabricated device. Anal Chem. 2004;76(20):6137-43 - PMID: 15481964 - DOI: 10.1021/ac0497508

  • Carter EA, Burks D, Fischman AJ, White M, Tompkins RG Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue. Int J Mol Med. 2004;14(4):653-8 - PMID: 15375597

  • Herndon DN, Tompkins RG Support of the metabolic response to burn injury. Lancet. 2004;363(9424):1895-902 - PMID: 15183630 - DOI: 10.1016/S0140-6736(04)16360-5

  • Sheridan RL, Prelack K, Yu YM, Lydon M, Petras L, Young VR, Tompkins RG Short-term enteral glutamine does not enhance protein accretion in burned children: a stable isotope study. Surgery. 2004;135(6):671-8 - PMID: 15179374 - DOI: 10.1016/j.surg.2003.11.014

  • Sugimachi K, Sosef MN, Baust JM, Fowler A, Tompkins RG, Toner M Long-term function of cryopreserved rat hepatocytes in a coculture system. Cell Transplant. 2004;13(2):187-95 - PMID: 15129765 - DOI: 10.3727/000000004773301799

  • Shen Y, Jacobs JM, Camp DG, Fang R, Moore RJ, Smith RD, Xiao W, Davis RW, Tompkins RG Ultra-high-efficiency strong cation exchange LC/RPLC/MS/MS for high dynamic range characterization of the human plasma proteome. Anal Chem. 2004;76(4):1134-44 - PMID: 14961748 - DOI: 10.1021/ac034869m

  • Sheridan RL, Tompkins RG What's new in burns and metabolism. J Am Coll Surg. 2004;198(2):243-63 - PMID: 14759783 - DOI: 10.1016/j.jamcollsurg.2003.11.007

  • Mokuno Y, Berthiaume F, Tompkins RG, Balis UJ, Yarmush ML Technique for expanding the donor liver pool: heat shock preconditioning in a rat fatty liver model. Liver Transpl. 2004;10(2):264-72 - PMID: 14762865 - DOI: 10.1002/lt.20014

  • Déziel E, Lépine F, Milot S, He J, Mindrinos MN, Tompkins RG, Rahme LG Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication. Proc Natl Acad Sci U S A. 2004;101(5):1339-44 - PMID: 14739337 - PMCID: PMC337054 - DOI: 10.1073/pnas.0307694100

  • Chen CL, Fei Z, Carter EA, Lu XM, Hu RH, Young VR, Tompkins RG, Yu YM Metabolic fate of extrahepatic arginine in liver after burn injury. Metabolism. 2003;52(10):1232-9 - PMID: 14564672 - DOI: 10.1016/s0026-0495(03)00282-8

  • Pawlik TM, Carter EA, Bode BP, Fischman AJ, Tompkins RG Central role of interleukin-6 in burn induced stimulation of hepatic amino acid transport. Int J Mol Med. 2003;12(4):541-8 - PMID: 12964032

  • Lau GW, Goumnerov BC, Walendziewicz CL, Hewitson J, Xiao W, Mahajan-Miklos S, Tompkins RG, Perkins LA, Rahme LG The Drosophila melanogaster toll pathway participates in resistance to infection by the gram-negative human pathogen Pseudomonas aeruginosa. Infect Immun. 2003;71(7):4059-66 - PMID: 12819096 - PMCID: PMC162001 - DOI: 10.1128/iai.71.7.4059-4066.2003

  • Shito M, Tilles AW, Tompkins RG, Yarmush ML, Toner M Efficacy of an extracorporeal flat-plate bioartificial liver in treating fulminant hepatic failure. J Surg Res. 2003;111(1):53-62 - PMID: 12842448 - DOI: 10.1016/s0022-4804(03)00048-9

  • Tilles AW, Berthiaume F, Yarmush ML, Tompkins RG, Toner M Bioengineering of liver assist devices. J Hepatobiliary Pancreat Surg. 2003;9(6):686-96 - PMID: 12658402 - DOI: 10.1007/s005340200095

  • Ryan CM, Schoenfeld DA, Malloy M, Schulz JT, Sheridan RL, Tompkins RG Use of Integra artificial skin is associated with decreased length of stay for severely injured adult burn survivors. J Burn Care Rehabil. 2002;23(5):311-7 - PMID: 12352131 - DOI: 10.1097/00004630-200209000-00002

  • Weber JM, Sheridan RL, Schulz JT, Tompkins RG, Ryan CM Effectiveness of bacteria-controlled nursing units in preventing cross-colonization with resistant bacteria in severely burned children. Infect Control Hosp Epidemiol. 2002;23(9):549-51 - PMID: 12269456 - DOI: 10.1086/502106

  • Fischman AJ, Hsu H, Carter EA, Yu YM, Tompkins RG, Guerrero JL, Young VR, Alpert NM Regional measurement of canine skeletal muscle blood flow by positron emission tomography with H2(15)O. J Appl Physiol. 2002;92(4):1709-16 - PMID: 11896041 - DOI: 10.1152/japplphysiol.00445.2001

  • Alpert NM, Rabito CA, Correia DJ, Babich JW, Littman BH, Tompkins RG, Rubin NT, Rubin RH, Fischman AJ Mapping of local renal blood flow with PET and H(2)(15)O. J Nucl Med. 2002;43(4):470-5 - PMID: 11937589

  • Sugita H, Kaneki M, Tokunaga E, Sugita M, Koike C, Yasuhara S, Tompkins RG, Martyn JA Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance. Am J Physiol Endocrinol Metab. 2002;282(2):E386-94 - PMID: 11788371 - DOI: 10.1152/ajpendo.00087.2001

  • Yu YM, Ryan CM, Fei ZW, Lu XM, Castillo L, Schultz JT, Tompkins RG, Young VR Plasma L-5-oxoproline kinetics and whole blood glutathione synthesis rates in severely burned adult humans. Am J Physiol Endocrinol Metab. 2002;282(2):E247-58 - PMID: 11788355 - DOI: 10.1152/ajpendo.00206.2001

  • Sheridan RL, Schulz JT, Ryan CM, Schnitzer JJ, Lawlor D, Driscoll DN, Donelan MB, Tompkins RG Long-term consequences of toxic epidermal necrolysis in children. Pediatrics. 2002;109(1):74-8 - PMID: 11773544 - DOI: 10.1542/peds.109.1.74

  • Washizu J, Berthiaume F, Mokuno Y, Tompkins RG, Toner M, Yarmush ML Long-term maintenance of cytochrome P450 activities by rat hepatocyte/3T3 cell co-cultures in heparinized human plasma. Tissue Eng. 2001;7(6):691-703 - PMID: 11749727 - DOI: 10.1089/107632701753337654

  • Tompkins RG The American Burn Association in the New Millennium. J Burn Care Rehabil. 2001;22(6):369-374 - PMID: 11773770 - DOI: 10.1097/00004630-200111000-00004

  • Sheridan RL, Weber JM, Pasternack MS, Tompkins RG Antibiotic prophylaxis for group A streptococcal burn wound infection is not necessary. J Trauma. 2001;51(2):352-5 - PMID: 11493799 - DOI: 10.1097/00005373-200108000-00022

  • Arai K, Lee K, Berthiaume F, Tompkins RG, Yarmush ML Intrahepatic amino acid and glucose metabolism in a D-galactosamine-induced rat liver failure model. Hepatology. 2001;34(2):360-71 - PMID: 11481621 - DOI: 10.1053/jhep.2001.26515

  • Shito M, Balis UJ, Tompkins RG, Yarmush ML, Toner M A fulminant hepatic failure model in the rat: involvement of interleukin-1beta and tumor necrosis factor-alpha. Dig Dis Sci. 2001;46(8):1700-8 - PMID: 11508670 - DOI: 10.1023/a:1010653504568

  • Sheridan RL, Morgan JR, Cusick JL, Petras LM, Lydon MM, Tompkins RG Initial experience with a composite autologous skin substitute. Burns. 2001;27(5):421-4 - PMID: 11451592 - DOI: 10.1016/s0305-4179(00)00156-x

  • Sheridan RL, Weber JM, Schnitzer JJ, Schulz JT, Ryan CM, Tompkins RG Young age is not a predictor of mortality in burns. Pediatr Crit Care Med. 2001;2(3):223-224 - PMID: 12793945 - DOI: 10.1097/00130478-200107000-00006

  • Shito M, Kim NH, Baskaran H, Tilles AW, Tompkins RG, Yarmush ML, Toner M In vitro and in vivo evaluation of albumin synthesis rate of porcine hepatocytes in a flat-plate bioreactor. Artif Organs. 2001;25(7):571-8 - PMID: 11493279 - DOI: 10.1046/j.1525-1594.2001.025007571.x

  • Yu YM, Ryan CM, Castillo L, Lu XM, Beaumier L, Tompkins RG, Young VR Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal. Am J Physiol Endocrinol Metab. 2001;280(3):E509-17 - PMID: 11171607 - DOI: 10.1152/ajpendo.2001.280.3.E509

  • Sheridan RL, Schulz JT, Weber JM, Ryan CM, Pasternack MS, Tompkins RG Cutaneous herpetic infections complicating burns. Burns. 2000;26(7):621-4 - PMID: 10925184 - DOI: 10.1016/s0305-4179(00)00025-5

  • Schulz JT, Sheridan RL, Ryan CM, MacKool B, Tompkins RG A 10-year experience with toxic epidermal necrolysis. J Burn Care Rehabil. 2000;21(3):199-204 - PMID: 10850900 - DOI: 10.1097/00004630-200021030-00004

  • Washizu J, Berthiaume F, Chan C, Tompkins RG, Toner M, Yarmush ML Optimization of rat hepatocyte culture in citrated human plasma. J Surg Res. 2000;93(2):237-46 - PMID: 11027466 - DOI: 10.1006/jsre.2000.5986

  • Washizu J, Chan C, Berthiaume F, Tompkins RG, Toner M, Yarmush ML Amino acid supplementation improves cell-specific functions of the rat hepatocytes exposed to human plasma. Tissue Eng. 2000;6(5):497-504 - PMID: 11074936 - DOI: 10.1089/107632700750022143

  • Rahme LG, Ausubel FM, Cao H, Drenkard E, Goumnerov BC, Lau GW, Mahajan-Miklos S, Plotnikova J, Tan MW, Tsongalis J, Walendziewicz CL, Tompkins RG Plants and animals share functionally common bacterial virulence factors. Proc Natl Acad Sci U S A. 2000;97(16):8815-21 - PMID: 10922040 - PMCID: PMC34017 - DOI: 10.1073/pnas.97.16.8815

  • Schulz JT, Tompkins RG, Burke JF Artificial skin. Annu Rev Med. 2000;51:231-44 - PMID: 10774462 - DOI: 10.1146/annurev.med.51.1.231

  • Lyons J, Rauh-Pfeiffer A, Yu YM, Lu XM, Zurakowski D, Tompkins RG, Ajami AM, Young VR, Castillo L Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet. Proc Natl Acad Sci U S A. 2000;97(10):5071-6 - PMID: 10792033 - PMCID: PMC25783 - DOI: 10.1073/pnas.090083297

  • Sheridan RL, Remensnyder JP, Schnitzer JJ, Schulz JT, Ryan CM, Tompkins RG Current expectations for survival in pediatric burns. Arch Pediatr Adolesc Med. 2000;154(3):245-9 - PMID: 10710021 - DOI: 10.1001/archpedi.154.3.245

  • Sheridan RL, Weber JM, Schulz JT, Ryan CM, Low HM, Tompkins RG Management of severe toxic epidermal necrolysis in children. J Burn Care Rehabil. 2000;20(6):497-500 - PMID: 10613688 - DOI: 10.1097/00004630-199920060-00012

  • Sheridan RL, Hinson MI, Liang MH, Nackel AF, Schoenfeld DA, Ryan CM, Mulligan JL, Tompkins RG Long-term outcome of children surviving massive burns. JAMA. 2000;283(1):69-73 - PMID: 10632282 - DOI: 10.1001/jama.283.1.69

  • Sheridan RL, Zapol WM, Ritz RH, Tompkins RG Low-dose inhaled nitric oxide in acutely burned children with profound respiratory failure. Surgery. 1999;126(5):856-62 - PMID: 10568185

  • Yarmush DM, MacDonald AD, Foy BD, Berthiaume F, Tompkins RG, Yarmush ML Cutaneous burn injury alters relative tricarboxylic acid cycle fluxes in rat liver. J Burn Care Rehabil. 1999;20(4):292-302 - PMID: 10425591 - DOI: 10.1097/00004630-199907000-00004

  • Carter EA, Yu YM, Alpert NM, Bonab AA, Tompkins RG, Fischman AJ Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine: effects of transamination and transmethylation. J Trauma. 1999;47(2):341-5 - PMID: 10452471 - DOI: 10.1097/00005373-199908000-00021

  • Ikezu T, Yasuhara S, Granneman JG, Kraemer FB, Okamoto T, Tompkins RG, Martyn JA A unique mechanism of desensitization to lipolysis mediated by beta(3)-adrenoceptor in rats with thermal injury. Am J Physiol. 1999;277(2):E316-24 - PMID: 10444428 - DOI: 10.1152/ajpendo.1999.277.2.E316

  • Yu YM, Tompkins RG, Ryan CM, Young VR The metabolic basis of the increase of the increase in energy expenditure in severely burned patients. JPEN J Parenter Enteral Nutr. 1999;23(3):160-8 - PMID: 10338224 - DOI: 10.1177/0148607199023003160

  • Sheridan RL, Weber JM, Pasternak MM, Mulligan JM, Tompkins RG A 15-year experience with varicella infections in a pediatric burn unit. Burns. 1999;25(4):353-6 - PMID: 10431985 - DOI: 10.1016/s0305-4179(99)00003-0

  • Sheridan RL, Baryza MJ, Pessina MA, O'Neill KM, Cipullo HM, Donelan MB, Ryan CM, Schulz JT, Schnitzer JJ, Tompkins RG Acute hand burns in children: management and long-term outcome based on a 10-year experience with 698 injured hands. Ann Surg. 1999;229(4):558-64 - PMID: 10203090 - PMCID: PMC1191743 - DOI: 10.1097/00000658-199904000-00016

  • Tan MW, Rahme LG, Sternberg JA, Tompkins RG, Ausubel FM Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Proc Natl Acad Sci U S A. 1999;96(5):2408-13 - PMID: 10051655 - PMCID: PMC26797 - DOI: 10.1073/pnas.96.5.2408

  • Sheridan RL, Tompkins RG Skin substitutes in burns. Burns. 1999;25(2):97-103 - PMID: 10208382 - DOI: 10.1016/s0305-4179(98)00176-4

  • Sheridan RL, Lydon MM, Petras LM, Schomacker KT, Tompkins RG, Glatter RD, Parrish JA Laser ablation of burns: initial clinical trial. Surgery. 1999;125(1):92-5 - PMID: 9889803

  • Medalie DA, Tompkins RG, Morgan JR Characterization of a composite tissue model that supports clonal growth of human melanocytes in vitro and in vivo. J Invest Dermatol. 1998;111(5):810-6 - PMID: 9804343 - DOI: 10.1046/j.1523-1747.1998.00368.x

  • Fischman AJ, Yu YM, Livni E, Babich JW, Young VR, Alpert NM, Tompkins RG Muscle protein synthesis by positron-emission tomography with L-[methyl-11C]methionine in adult humans. Proc Natl Acad Sci U S A. 1998;95(22):12793-8 - PMID: 9788993 - PMCID: PMC23595 - DOI: 10.1073/pnas.95.22.12793

  • Sheridan RL, Yu YM, Prelack K, Young VR, Burke JF, Tompkins RG Maximal parenteral glucose oxidation in hypermetabolic young children: a stable isotope study. JPEN J Parenter Enteral Nutr. 1998;22(4):212-6 - PMID: 9661121 - DOI: 10.1177/0148607198022004212

  • Takabayashi T, Vannier E, Burke JF, Tompkins RG, Gelfand JA, Clark BD Both C3a and C3a(desArg) regulate interleukin-6 synthesis in human peripheral blood mononuclear cells. J Infect Dis. 1998;177(6):1622-8 - PMID: 9607842 - DOI: 10.1086/515316

  • Sheridan RL, Ryan CM, Yin LM, Hurley J, Tompkins RG Death in the burn unit: sterile multiple organ failure. Burns. 1998;24(4):307-11 - PMID: 9688194 - DOI: 10.1016/s0305-4179(97)00062-4

  • Hu RH, Yu YM, Costa D, Young VR, Ryan CM, Burke JF, Tompkins RG A rabbit model for metabolic studies after burn injury. J Surg Res. 1998;75(2):153-60 - PMID: 9655088 - DOI: 10.1006/jsre.1998.5274

  • Eming SA, Medalie DA, Tompkins RG, Yarmush ML, Morgan JR Genetically modified human keratinocytes overexpressing PDGF-A enhance the performance of a composite skin graft. Hum Gene Ther. 1998;9(4):529-39 - PMID: 9525314 - DOI: 10.1089/hum.1998.9.4-529

  • Ryan CM, Schoenfeld DA, Thorpe WP, Sheridan RL, Cassem EH, Tompkins RG Objective estimates of the probability of death from burn injuries. N Engl J Med. 1998;338(6):362-6 - PMID: 9449729 - DOI: 10.1056/NEJM199802053380604

  • Bischof JC, Ryan CM, Tompkins RG, Yarmush ML, Toner M Ice formation in isolated human hepatocytes and human liver tissue. ASAIO J. 1997;43(4):271-8 - PMID: 9242939

  • Rahme LG, Tan MW, Le L, Wong SM, Tompkins RG, Calderwood SB, Ausubel FM Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors. Proc Natl Acad Sci U S A. 1997;94(24):13245-50 - PMID: 9371831 - PMCID: PMC24294 - DOI: 10.1073/pnas.94.24.13245

  • Ikezu T, Okamoto T, Yonezawa K, Tompkins RG, Martyn JA Analysis of thermal injury-induced insulin resistance in rodents. Implication of postreceptor mechanisms. J Biol Chem. 1997;272(40):25289-95 - PMID: 9312146 - DOI: 10.1074/jbc.272.40.25289

  • Sheridan RL, Ryan CM, Petras LM, Lydon MK, Weber JM, Tompkins RG Burns in children younger than two years of age: an experience with 200 consecutive admissions. Pediatrics. 1997;100(4):721-3 - PMID: 9310533 - DOI: 10.1542/peds.100.4.721

  • Reiken SR, Wolfort SF, Berthiaume F, Compton C, Tompkins RG, Yarmush ML Control of hypertrophic scar growth using selective photothermolysis. Lasers Surg Med. 1997;21(1):7-12 - PMID: 9228634 - DOI: 10.1002/(sici)1096-9101(1997)21:1<7::aid-lsm2>3.0.co;2-u

  • Babich JW, Tompkins RG, Graham W, Barrow SA, Fischman AJ Localization of radiolabeled chemotactic peptide at focal sites of Escherichia coli infection in rabbits: evidence for a receptor-specific mechanism. J Nucl Med. 1997;38(8):1316-22 - PMID: 9255175

  • Medalie DA, Eming SA, Collins ME, Tompkins RG, Yarmush ML, Morgan JR Differences in dermal analogs influence subsequent pigmentation, epidermal differentiation, basement membrane, and rete ridge formation of transplanted composite skin grafts. Transplantation. 1997;64(3):454-65 - PMID: 9275113 - DOI: 10.1097/00007890-199708150-00015

  • Carter EA, Tompkins RG, Hsu H, Christian B, Alpert NM, Weise S, Fischman AJ Metabolic alterations in muscle of thermally injured rabbits, measured by positron emission tomography. Life Sci. 1997;61(1):39-44 - PMID: 9200667 - DOI: 10.1016/s0024-3205(97)00355-x

  • Prelack K, Cunningham JJ, Sheridan RL, Tompkins RG Energy and protein provisions for thermally injured children revisited: an outcome-based approach for determining requirements. J Burn Care Rehabil. 1997;18(2):177-81; discussion 176 - PMID: 9095430 - DOI: 10.1097/00004630-199703000-00015

  • Weber JM, Sheridan RL, Pasternack MS, Tompkins RG Nosocomial infections in pediatric patients with burns. Am J Infect Control. 1997;25(3):195-201 - PMID: 9202814 - DOI: 10.1016/s0196-6553(97)90004-3

  • Vogt JA, Yarmush DM, Yu YM, Zupke C, Fischman AJ, Tompkins RG, Burke JF TCA cycle flux estimates from NMR- and GC-MS-determined [13C]glutamate isotopomers in liver. Am J Physiol. 1997;272(6 Pt 1):C2049-62 - PMID: 9227434 - DOI: 10.1152/ajpcell.1997.272.6.C2049

  • Prelack K, Dwyer J, Yu YM, Sheridan RL, Tompkins RG Urinary urea nitrogen is imprecise as a predictor of protein balance in burned children. J Am Diet Assoc. 1997;97(5):489-95 - PMID: 9145086 - DOI: 10.1016/S0002-8223(97)00127-2

  • Sheridan RL, Hurford WE, Kacmarek RM, Ritz RH, Yin LM, Ryan CM, Tompkins RG Inhaled nitric oxide in burn patients with respiratory failure. J Trauma. 1997;42(4):629-34 - PMID: 9137249 - DOI: 10.1097/00005373-199704000-00008

  • Medalie DA, Tompkins RG, Morgan JR Evaluation of acellular human dermis as a dermal analog in a composite skin graft. ASAIO J. 1997;42(5):M455-62 - PMID: 8944923 - DOI: 10.1097/00002480-199609000-00030

  • Yamaguchi Y, Yu YM, Zupke C, Yarmush DM, Berthiaume F, Tompkins RG, Yarmush ML Effect of burn injury on glucose and nitrogen metabolism in the liver: preliminary studies in a perfused liver system. Surgery. 1997;121(3):295-303 - PMID: 9092130 - DOI: 10.1016/s0039-6060(97)90358-5

  • Tompkins RG The role of proinflammatory cytokines in inflammatory and metabolic responses. Ann Surg. 1997;225(3):243-5 - PMID: 9060578 - PMCID: PMC1190672 - DOI: 10.1097/00000658-199703000-00001

  • Aiura K, Clark BD, Dinarello CA, Margolis NH, Kaplanski G, Burke JF, Tompkins RG, Gelfand JA Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells. J Infect Dis. 1997;175(1):123-9 - PMID: 8985205 - DOI: 10.1093/infdis/175.1.123

  • Yu YM, Burke JF, Tompkins RG, Martin R, Young VR Quantitative aspects of interorgan relationships among arginine and citrulline metabolism. Am J Physiol. 1996;271(6 Pt 1):E1098-109 - PMID: 8997231 - DOI: 10.1152/ajpendo.1996.271.6.E1098

  • Stefanovich P, Matthew HW, Toner M, Tompkins RG, Yarmush ML Extracorporeal plasma perfusion of cultured hepatocytes: effect of intermittent perfusion on hepatocyte function and morphology. J Surg Res. 1996;66(1):57-63 - PMID: 8954832 - DOI: 10.1006/jsre.1996.0372

  • Carter EA, Tompkins RG, Babich JW, Correia J, Bailey EM, Fischman AJ Thermal injury in rats alters glucose utilization by skin, wound, and small intestine, but not by skeletal muscle. Metabolism. 1996;45(9):1161-7 - PMID: 8781305 - DOI: 10.1016/s0026-0495(96)90017-7

  • Matthew HW, Sternberg J, Stefanovich P, Morgan JR, Toner M, Tompkins RG, Yarmush ML Effects of plasma exposure on cultured hepatocytes: Implications for bioartificial liver support. Biotechnol Bioeng. 1996;51(1):100-11 - PMID: 18627093 - DOI: 10.1002/(SICI)1097-0290(19960705)51:1<100::AID-BIT12>3.0.CO;2-U

  • Yu YM, Sheridan RL, Burke JF, Chapman TE, Tompkins RG, Young VR Kinetics of plasma arginine and leucine in pediatric burn patients. Am J Clin Nutr. 1996;64(1):60-6 - PMID: 8669415 - DOI: 10.1093/ajcn/64.1.60

  • Medalie DA, Eming SA, Tompkins RG, Yarmush ML, Krueger GG, Morgan JR Evaluation of human skin reconstituted from composite grafts of cultured keratinocytes and human acellular dermis transplanted to athymic mice. J Invest Dermatol. 1996;107(1):121-7 - PMID: 8752850 - DOI: 10.1111/1523-1747.ep12298363

  • Carter EA, Tompkins RG, Babich JW, Correia JA, Fischman AJ Decreased cerebral glucose utilization in rats during the ebb phase of thermal injury. J Trauma. 1996;40(6):930-5 - PMID: 8656479 - DOI: 10.1097/00005373-199606000-00011

  • Wolfort SF, Reiken SR, Berthiaume F, Tompkins RG, Yarmush ML Control of hypertrophic scar growth using antibody-targeted photolysis. J Surg Res. 1996;62(1):17-22 - PMID: 8606503 - DOI: 10.1006/jsre.1996.0166

  • Sheridan RL, Schomaker KT, Lucchina LC, Hurley J, Yin LM, Tompkins RG, Jerath M, Torri A, Greaves KW, Bua DP Burn depth estimation by use of indocyanine green fluorescence: initial human trial. J Burn Care Rehabil. 1996;16(6):602-4 - PMID: 8582937 - DOI: 10.1097/00004630-199511000-00007

  • Sheridan RL, Petras L, Basha G, Salvo P, Cifrino C, Hinson M, McCabe M, Fallon J, Tompkins RG Planimetry study of the percent of body surface represented by the hand and palm: sizing irregular burns is more accurately done with the palm. J Burn Care Rehabil. 1996;16(6):605-6 - PMID: 8582938 - DOI: 10.1097/00004630-199511000-00008

  • Sheridan RL, Behringer GE, Ryan CM, Bondoc CC, Quinby WC, Tompkins RG, Burke JF Effective postoperative protection for grafted posterior surfaces: the quilted dressing. J Burn Care Rehabil. 1996;16(6):607-9 - PMID: 8582939 - DOI: 10.1097/00004630-199511000-00009

  • Sheridan RL, Weber JM, Budkevich LG, Tompkins RG Candidemia in the pediatric patient with burns. J Burn Care Rehabil. 1996;16(4):440-3 - PMID: 8582925 - DOI: 10.1097/00004630-199507000-00011

  • Hansbrough JF, Herndon DN, Heimbach DM, Solem LD, Gamelli RL, Tompkins RG Accelerated healing and reduced need for grafting in pediatric patients with burns treated with arginine-glycine-aspartic acid peptide matrix. RGD Study Group. J Burn Care Rehabil. 1996;16(4):377-87 - PMID: 8582916 - DOI: 10.1097/00004630-199507000-00002

  • Hsu H, Yu YM, Babich JW, Burke JF, Livni E, Tompkins RG, Young VR, Alpert NM, Fischman AJ Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine. Proc Natl Acad Sci U S A. 1996;93(5):1841-6 - PMID: 8700846 - PMCID: PMC39869 - DOI: 10.1073/pnas.93.5.1841

  • Yu YM, Young VR, Tompkins RG, Burke JF Comparative evaluation of the quantitative utilization of parenterally and enterally administered leucine and L-[1-13C,15N]leucine within the whole body and the splanchnic region. JPEN J Parenter Enteral Nutr. 1996;19(3):209-15 - PMID: 8551649 - DOI: 10.1177/0148607195019003209

  • Moghe PV, Berthiaume F, Ezzell RM, Toner M, Tompkins RG, Yarmush ML Culture matrix configuration and composition in the maintenance of hepatocyte polarity and function. Biomaterials. 1996;17(3):373-85 - PMID: 8745335 - DOI: 10.1016/0142-9612(96)85576-1

  • Sheridan RL, Briggs SE, Remensnyder JP, Tompkins RG Management strategy in purpura fulminans with multiple organ failure in children. Burns. 1996;22(1):53-6 - PMID: 8719318 - DOI: 10.1016/0305-4179(95)00078-x

  • Sheridan RL, Tompkins RG Recent clinical experience with cultured autologous epithelium. Br J Plast Surg. 1996;49(1):72-4 - PMID: 8705108 - DOI: 10.1016/s0007-1226(96)90193-9

  • Eming SA, Lee J, Snow RG, Tompkins RG, Yarmush ML, Morgan JR Genetically modified human epidermis overexpressing PDGF-A directs the development of a cellular and vascular connective tissue stroma when transplanted to athymic mice--implications for the use of genetically modified keratinocytes to modulate dermal regeneration. J Invest Dermatol. 1995;105(6):756-63 - PMID: 7490468 - DOI: 10.1111/1523-1747.ep12325550

  • Morgan JR, LeDoux JM, Snow RG, Tompkins RG, Yarmush ML Retrovirus infection: effect of time and target cell number. J Virol. 1995;69(11):6994-7000 - PMID: 7474118 - PMCID: PMC189618 - DOI: 10.1128/JVI.69.11.6994-7000.1995

  • Ryan CM, Atkins MB, Mier JW, Gelfand JA, Tompkins RG Effects of malignancy and interleukin-2 infusion on gut macromolecular permeability. Crit Care Med. 1995;23(11):1801-6 - PMID: 7587254 - DOI: 10.1097/00003246-199511000-00003

  • Yu YM, Ryan CM, Burke JF, Tompkins RG, Young VR Relations among arginine, citrulline, ornithine, and leucine kinetics in adult burn patients. Am J Clin Nutr. 1995;62(5):960-8 - PMID: 7572742 - DOI: 10.1093/ajcn/62.5.960

  • Sheridan RL, Kacmarek RM, McEttrick MM, Weber JM, Ryan CM, Doody DP, Ryan DP, Schnitzer JJ, Tompkins RG Permissive hypercapnia as a ventilatory strategy in burned children: effect on barotrauma, pneumonia, and mortality. J Trauma. 1995;39(5):854-9 - PMID: 7474000 - DOI: 10.1097/00005373-199511000-00008

  • Stefanovich P, Ezzell RM, Sheehan SJ, Tompkins RG, Yarmush ML, Toner M Effects of hypothermia on the function, membrane integrity, and cytoskeletal structure of hepatocytes. Cryobiology. 1995;32(4):389-403 - PMID: 7656572 - DOI: 10.1006/cryo.1995.1039

  • Ryan CM, Sheridan RL, Schoenfeld DA, Warshaw AL, Tompkins RG Postburn pancreatitis. Ann Surg. 1995;222(2):163-70 - PMID: 7543741 - PMCID: PMC1234774 - DOI: 10.1097/00000658-199508000-00008

  • Sheridan RL, Petras L, Basha G, Tompkins RG Clinical experience with the use of biodegradable tacks in pediatric patients with burns. J Burn Care Rehabil. 1995;16(2 Pt 1):143-4 - PMID: 7775509 - DOI: 10.1097/00004630-199503000-00010

  • Rahme LG, Stevens EJ, Wolfort SF, Shao J, Tompkins RG, Ausubel FM Common virulence factors for bacterial pathogenicity in plants and animals. Science. 1995;268(5219):1899-902 - PMID: 7604262 - DOI: 10.1126/science.7604262

  • Bischof JC, Padanilam J, Holmes WH, Ezzell RM, Lee RC, Tompkins RG, Yarmush ML, Toner M Dynamics of cell membrane permeability changes at supraphysiological temperatures. Biophys J. 1995;68(6):2608-14 - PMID: 7647264 - PMCID: PMC1282171 - DOI: 10.1016/S0006-3495(95)80445-5

  • Sheridan RL, Briggs SE, Remensnyder JP, Gagnon SW, Doody DP, Ryan DP, Tompkins RG The burn unit as a resource for the management of acute nonburn conditions in children. J Burn Care Rehabil. 1995;16(1):62-4 - PMID: 7721912 - DOI: 10.1097/00004630-199501000-00012

  • Sheridan RL, Stewart B, Tompkins RG Solid organ procurement from burn patients. J Trauma. 1995;38(5):824-5 - PMID: 7760420 - DOI: 10.1097/00005373-199505000-00029

  • Thorpe WP, Toner M, Ezzell RM, Tompkins RG, Yarmush ML Dynamics of photoinduced cell plasma membrane injury. Biophys J. 1995;68(5):2198-206 - PMID: 7612864 - PMCID: PMC1282125 - DOI: 10.1016/S0006-3495(95)80402-9

  • Yu YM, Young VR, Castillo L, Chapman TE, Tompkins RG, Ryan CM, Burke JF Plasma arginine and leucine kinetics and urea production rates in burn patients. Metabolism. 1995;44(5):659-66 - PMID: 7752916 - DOI: 10.1016/0026-0495(95)90125-6

  • Foy BD, Rotem A, Toner M, Tompkins RG, Yarmush ML A device to measure the oxygen uptake rate of attached cells: importance in bioartificial organ design. Cell Transplant. 1995;3(6):515-27 - PMID: 7881763 - DOI: 10.1177/096368979400300609

  • Rotem A, Matthew HW, Hsiao PH, Toner M, Tompkins RG, Yarmush ML The activity of cytochrome P450IA1 in stable cultured rat hepatocytes. Toxicol In Vitro. 1995;9(2):139-49 - PMID: 20650073 - DOI: 10.1016/0887-2333(94)00207-b

  • Sheridan RL, McEttrick M, Bacha G, Stoddard F, Tompkins RG Midazolam infusion in pediatric patients with burns who are undergoing mechanical ventilation. J Burn Care Rehabil. 1995;15(6):515-8 - PMID: 7852455 - DOI: 10.1097/00004630-199411000-00009

  • Sheridan RL, Hurley J, Smith MA, Ryan CM, Bondoc CC, Quinby WC, Tompkins RG, Burke JF The acutely burned hand: management and outcome based on a ten-year experience with 1047 acute hand burns. J Trauma. 1995;38(3):406-11 - PMID: 7897728 - DOI: 10.1097/00005373-199503000-00022

  • Sheridan RL, Weber JM, Peterson HF, Tompkins RG Central venous catheter sepsis with weekly catheter change in paediatric burn patients: an analysis of 221 catheters. Burns. 1995;21(2):127-9 - PMID: 7766321 - DOI: 10.1016/0305-4179(95)92137-2

  • Sheridan RL, Ryan CM, Quinby WC, Blair J, Tompkins RG, Burke JF Emergency management of major hydrofluoric acid exposures. Burns. 1995;21(1):62-4 - PMID: 7718123 - DOI: 10.1016/0305-4179(95)90785-x

  • Sheridan RL, Ryan CM, Lee MJ, Mueller PR, Tompkins RG Percutaneous cholecystostomy in the critically ill burn patient. J Trauma. 1995;38(2):248-51 - PMID: 7869446 - DOI: 10.1097/00005373-199502000-00019

  • Fischman AJ, Babich JW, Barrow SA, Graham W, Carter E, Tompkins RG, Rubin RH Detection of acute bacterial infection within soft tissue injuries using a 99mTc-labeled chemotactic peptide. J Trauma. 1995;38(2):223-7 - PMID: 7869440 - DOI: 10.1097/00005373-199502000-00013

  • Sheridan RL, Hurley J, Lynch L, Balmer J, Ryan CM, Bondoc CC, Quinby WC, Tompkins RG, Burke JF Modified Stryker frame for intraoperative positioning of the patient with burns. J Burn Care Rehabil. 1995;15(5):438-40 - PMID: 7995819 - DOI: 10.1097/00004630-199409000-00012

  • Sheridan RL, Tompkins RG Cultured autologous epithelium in patients with burns of ninety percent or more of the body surface. J Trauma. 1995;38(1):48-50 - PMID: 7745657 - DOI: 10.1097/00005373-199501000-00014

  • Souba WW, Gamelli RL, Lorber MI, Thompson JS, Kron IL, Tompkins RG, Hoyt DB Strategies for success in academic surgery. Surgery. 1995;117(1):90-5 - PMID: 7809842 - DOI: 10.1016/s0039-6060(05)80234-x

  • Sheridan RL, Prelack KM, Petras LM, Szyfelbein SK, Tompkins RG Intraoperative reflectance oximetry in burn patients. J Clin Monit. 1995;11(1):32-4 - PMID: 7745451 - DOI: 10.1007/BF01627417

  • Bacha EA, Sheridan RL, Donohue GA, Tompkins RG Staphylococcal toxic shock syndrome in a paediatric burn unit. Burns. 1994;20(6):499-502 - PMID: 7880413 - DOI: 10.1016/0305-4179(94)90005-1

  • Sheridan RL, Weber J, Benjamin J, Pasternack MS, Tompkins RG Control of methicillin-resistant Staphylococcus aureus in a pediatric burn unit. Am J Infect Control. 1994;22(6):340-5 - PMID: 7695112 - DOI: 10.1016/0196-6553(94)90032-9

  • Bhatia SN, Toner M, Tompkins RG, Yarmush ML Selective adhesion of hepatocytes on patterned surfaces. Ann N Y Acad Sci. 1994;745:187-209 - PMID: 7832508 - DOI: 10.1111/j.1749-6632.1994.tb44373.x

  • Carter EA, Derojas-Walker T, Tamir S, Tannenbaum SR, Yu YM, Tompkins RG Nitric oxide production is intensely and persistently increased in tissue by thermal injury. Biochem J. 1994;304 ( Pt 1):201-4 - PMID: 7528006 - PMCID: PMC1137472 - DOI: 10.1042/bj3040201

  • Sheridan RL, Weber JM, Tompkins RG Femoral arterial catheterization in paediatric burn patients. Burns. 1994;20(5):451-2 - PMID: 7999277 - DOI: 10.1016/0305-4179(94)90041-8

  • Herman LW, Fischman AJ, Tompkins RG, Hanson RN, Byon C, Strauss HW, Elmaleh DR The use of pentafluorophenyl derivatives for the 18F labelling of proteins. Nucl Med Biol. 1994;21(7):1005-10 - PMID: 9234356 - DOI: 10.1016/0969-8051(94)90091-4

  • Morgan JR, Lee J, Tompkins RG, Yarmush ML Rapid quantitation of recombinant retroviruses. Biotechnol Prog. 1994;10(4):441-6 - PMID: 7765097 - DOI: 10.1021/bp00028a014

  • Stevens EJ, Ryan CM, Friedberg JS, Barnhill RL, Yarmush ML, Tompkins RG A quantitative model of invasive Pseudomonas infection in burn injury. J Burn Care Rehabil. 1994;15(3):232-5 - PMID: 8056812 - DOI: 10.1097/00004630-199405000-00005

  • Trop M, Carter EA, Schiffrin EJ, Tompkins RG Arterial blood pressure immediately after thermal injury: the role of anesthesia. J Burn Care Rehabil. 1994;15(3):224-31 - PMID: 8056811 - DOI: 10.1097/00004630-199405000-00004

  • Berthiaume F, Reiken SR, Toner M, Tompkins RG, Yarmush ML Antibody-targeted photolysis of bacteria in vivo. Biotechnology (N Y). 1994;12(7):703-6 - PMID: 7764916 - DOI: 10.1038/nbt0794-703

  • Carter EA, Tompkins RG Injury-induced inhibition of fat absorption. J Burn Care Rehabil. 1994;15(2):154-7 - PMID: 8195256 - DOI: 10.1097/00004630-199403000-00009

  • Vogt JA, Fischman AJ, Kempf M, Yu YM, Tompkins RG, Burke JF A general model for analysis of the tricarboxylic acid cycle with use of [13C]glutamate isotopomer measurements. Am J Physiol. 1994;266(6 Pt 1):E1012-22 - PMID: 7912892 - DOI: 10.1152/ajpendo.1994.266.6.E1012

  • Sheridan RL, Tompkins RG Prognostic significance of prehospital cardiac or pulmonary resuscitation in paediatric burns patients. Burns. 1994;20(3):265-6 - PMID: 8054145 - DOI: 10.1016/0305-4179(94)90198-8

  • Borel Rinkes IH, Toner M, Sheeha SJ, Tompkins RG, Yarmush ML Long-term functional recovery of hepatocytes after cryopreservation in a three-dimensional culture configuration. Cell Transplant. 1994;1(4):281-92 - PMID: 1344301 - DOI: 10.1177/096368979200100405

  • Yarmush ML, Dunn JC, Tompkins RG Assessment of artificial liver support technology. Cell Transplant. 1994;1(5):323-41 - PMID: 1344305 - DOI: 10.1177/096368979200100501

  • Padanilam JT, Bischof JC, Lee RC, Cravalho EG, Tompkins RG, Yarmush ML, Toner M Effectiveness of poloxamer 188 in arresting calcein leakage from thermally damaged isolated skeletal muscle cells. Ann N Y Acad Sci. 1994;720:111-23 - PMID: 7516633 - DOI: 10.1111/j.1749-6632.1994.tb30439.x

  • Borel Rinkes IH, Toner M, Tompkins RG, Yarmush ML An extracorporeal microscopy perfusion chamber for on-line studies of environmental effects on cultured hepatocytes. J Biomech Eng. 1994;116(2):135-9 - PMID: 8078319 - DOI: 10.1115/1.2895711

  • Meng J, Elmaleh DR, Jyawook S, Weiss S, Alpert NM, Babich JW, Tompkins RG, Fischman AJ Synthesis of 2-[18F]fluoro-2-deoxy-L-glucose and positron emission tomography studies in monkeys. Nucl Med Biol. 1994;21(4):633-40 - PMID: 9234321 - DOI: 10.1016/0969-8051(94)90029-9

  • Mester M, Carter EA, Tompkins RG, Gelfand JA, Dinarello CA, Burke JF, Clark BD Thermal injury induces very early production of interleukin-1 alpha in the rat by mechanisms other than endotoxemia. Surgery. 1994;115(5):588-96 - PMID: 8178258

  • Sheridan RL, Tompkins RG, Burke JF Prophylactic antibiotics and their role in the prevention of surgical wound infection. Adv Surg. 1994;27:43-65 - PMID: 8140979

  • Foy BD, Toner M, Tompkins RG, Yarmush ML Engineering organ perfusion protocols: NMR analysis of hepatocyte isolation from perfused rat liver. Biotechnol Bioeng. 1994;43(7):661-72 - PMID: 18615766 - DOI: 10.1002/bit.260430716

  • Rotem A, Toner M, Bhatia S, Foy BD, Tompkins RG, Yarmush ML Oxygen is a factor determining in vitro tissue assembly: Effects on attachment and spreading of hepatocytes. Biotechnol Bioeng. 1994;43(7):654-60 - PMID: 18615765 - DOI: 10.1002/bit.260430715

  • Sheridan RL, Tompkins RG, McManus WF, Pruitt BA Intracompartmental sepsis in burn patients. J Trauma. 1994;36(3):301-5 - PMID: 8145308 - DOI: 10.1097/00005373-199403000-00003

  • Ryan CM, Bailey SH, Carter EA, Schoenfeld DA, Tompkins RG Additive effects of thermal injury and infection on gut permeability. Arch Surg. 1994;129(3):325-8 - PMID: 8129610 - DOI: 10.1001/archsurg.1994.01420270103021

  • Berthiaume F, Ezzell RM, Toner M, Yarmush ML, Tompkins RG Transport of fluorescent dextrans across the rat ileum after cutaneous thermal injury. Crit Care Med. 1994;22(3):455-64 - PMID: 7510222 - DOI: 10.1097/00003246-199403000-00016

  • Lu XM, Fischman AJ, Jyawook SL, Hendricks K, Tompkins RG, Yarmush ML Antisense DNA delivery in vivo: liver targeting by receptor-mediated uptake. J Nucl Med. 1994;35(2):269-75 - PMID: 8294998

  • Yarmush ML, Thorpe WP, Strong L, Rakestraw SL, Toner M, Tompkins RG Antibody Targeted Photolysis. Crit Rev Ther Drug Carrier Syst. 1994;10(3):197-252 - PMID: 8258158

  • Ge Y, Ezzell RM, Tompkins RG, Warren HS Cellular distribution of endotoxin after injection of chemically purified lipopolysaccharide differs from that after injection of live bacteria. J Infect Dis. 1994;169(1):95-104 - PMID: 8277203 - DOI: 10.1093/infdis/169.1.95

  • Sheridan RL, Tompkins RG, Burke JF Management of burn wounds with prompt excision and immediate closure. J Intensive Care Med. 1994;9(1):6-17 - PMID: 10146651 - DOI: 10.1177/088506669400900103

  • Tompkins RG Human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome. Crit Care Med. 1994;22(1):3 - PMID: 8124969 - DOI: 10.1097/00003246-199401000-00002

  • Sheridan RL, Ryan CM, Tompkins RG An effective technique of scrotal harvest. J Burn Care Rehabil. 1993;14(5):557-8 - PMID: 8245111 - DOI: 10.1097/00004630-199309000-00011

  • Karlsson JO, Cravalho EG, Borel Rinkes IH, Tompkins RG, Yarmush ML, Toner M Nucleation and growth of ice crystals inside cultured hepatocytes during freezing in the presence of dimethyl sulfoxide. Biophys J. 1993;65(6):2524-36 - PMID: 8312489 - PMCID: PMC1225995 - DOI: 10.1016/S0006-3495(93)81319-5

  • Carter EA, Khalid MA, Burke JF, Tompkins RG Absence of change in hepatic lactate metabolism after burn injury. Burns. 1993;19(6):475-8 - PMID: 8292229 - DOI: 10.1016/0305-4179(93)90002-p

  • Babich JW, Graham W, Barrow SA, Dragotakes SC, Tompkins RG, Rubin RH, Fischman AJ Technetium-99m-labeled chemotactic peptides: comparison with indium-111-labeled white blood cells for localizing acute bacterial infection in the rabbit. J Nucl Med. 1993;34(12):2176-81 - PMID: 8254406

  • Fischman AJ, Rauh D, Solomon H, Babich JW, Tompkins RG, Kroon D, Strauss HW, Rubin RH In vivo bioactivity and biodistribution of chemotactic peptide analogs in nonhuman primates. J Nucl Med. 1993;34(12):2130-4 - PMID: 8254400

  • Babich JW, Solomon H, Pike MC, Kroon D, Graham W, Abrams MJ, Tompkins RG, Rubin RH, Fischman AJ Technetium-99m-labeled hydrazino nicotinamide derivatized chemotactic peptide analogs for imaging focal sites of bacterial infection. J Nucl Med. 1993;34(11):1964-74 - PMID: 8229242

  • Ezzell RM, Toner M, Hendricks K, Dunn JC, Tompkins RG, Yarmush ML Effect of collagen gel configuration on the cytoskeleton in cultured rat hepatocytes. Exp Cell Res. 1993;208(2):442-52 - PMID: 8375473 - DOI: 10.1006/excr.1993.1266

  • Ezzell RM, Carter EA, Yarmush ML, Tompkins RG Thermal injury-induced changes in the rat intestine brush border cytoskeleton. Surgery. 1993;114(3):591-7 - PMID: 8367816

  • Foy BD, Lee J, Morgan J, Toner M, Tompkins RG, Yarmush ML Optimization of hepatocyte attachment to microcarriers: Importance of oxygen. Biotechnol Bioeng. 1993;42(5):579-88 - PMID: 18613079 - DOI: 10.1002/bit.260420505

  • Horwitz JI, Toner M, Tompkins RG, Yarmush ML Immobilized IL-2 preserves the viability of an IL-2 dependent cell line. Mol Immunol. 1993;30(11):1041-8 - PMID: 8350874 - DOI: 10.1016/0161-5890(93)90129-y

  • Sheridan RL, Ryan CM, Pasternack MS, Weber JM, Tompkins RG Flavobacterial sepsis in massively burned pediatric patients. Clin Infect Dis. 1993;17(2):185-7 - PMID: 8399864

  • Toner M, Cravalho EG, Stachecki J, Fitzgerald T, Tompkins RG, Yarmush ML, Armant DR Nonequilibrium freezing of one-cell mouse embryos. Membrane integrity and developmental potential. Biophys J. 1993;64(6):1908-21 - PMID: 8369414 - PMCID: PMC1262525 - DOI: 10.1016/S0006-3495(93)81562-5

  • Mester M, Tompkins RG, Gelfand JA, Dinarello CA, Burke JF, Clark BD Intestinal production of interleukin-1 alpha during endotoxemia in the mouse. J Surg Res. 1993;54(6):584-91 - PMID: 8412068 - DOI: 10.1006/jsre.1993.1089

  • Lee J, Morgan JR, Tompkins RG, Yarmush ML Proline-mediated enhancement of hepatocyte function in a collagen gel sandwich culture configuration. FASEB J. 1993;7(6):586-91 - PMID: 8472895 - DOI: 10.1096/fasebj.7.6.8472895

  • Tompkins RG, Burke JF Burn wound closure using permanent skin replacement materials. World J Surg. 1993;16(1):47-52 - PMID: 1290266 - DOI: 10.1007/BF02067114

  • Dunn JC, Tompkins RG, Yarmush ML Dynamics of transcriptional and translational processes in hepatocytes cultured in a collagen sandwich. Biotechnol Bioeng. 1993;41(5):593-8 - PMID: 18609591 - DOI: 10.1002/bit.260410512

  • Ryan CM, Schmidt J, Lewandrowski K, Compton CC, Rattner DW, Warshaw AL, Tompkins RG Gut macromolecular permeability in pancreatitis correlates with severity of disease in rats. Gastroenterology. 1993;104(3):890-5 - PMID: 8440440 - DOI: 10.1016/0016-5085(93)91027-f

  • Sheridan RL, Ryan CM, Tompkins RG Acute adrenal insufficiency in the burn intensive care unit. Burns. 1993;19(1):63-6 - PMID: 8435119 - DOI: 10.1016/0305-4179(93)90103-f

  • Trop M, Tompkins RG, Schiffrin EJ, Carter EA, Burke JF Core body temperature responses immediately after cutaneous thermal injury in rats. J Burn Care Rehabil. 1993;13(6):632-8 - PMID: 1469027 - DOI: 10.1097/00004630-199211000-00005

  • Dunn JC, Friedberg JS, Tompkins RG, Yarmush ML Hepatocytes from rat liver perfusions. Physicochemical effects on polyribosome size. ASAIO J. 1993;38(4):841-5 - PMID: 1450483 - DOI: 10.1097/00002480-199210000-00019

  • Ryan CM, Carter EA, Jenkins RL, Sterling LM, Yarmush ML, Malt RA, Tompkins RG Isolation and long-term culture of human hepatocytes. Surgery. 1993;113(1):48-54 - PMID: 8417488

  • Sheridan RL, Sheridan MG, Tompkins RG Dishwasher effluent burns in infants. Pediatrics. 1993;91(1):142-4 - PMID: 8416479

  • Rotem A, Toner M, Tompkins RG, Yarmush ML Oxygen uptake rates in cultured rat hepatocytes. Biotechnol Bioeng. 1992;40(10):1286-91 - PMID: 18601082 - DOI: 10.1002/bit.260401020

  • Ryan CM, Yarmush ML, Burke JF, Tompkins RG Increased gut permeability early after burns correlates with the extent of burn injury. Crit Care Med. 1992;20(11):1508-12 - PMID: 1424691 - DOI: 10.1097/00003246-199211000-00005

  • Lu XM, Fischman AJ, Stevens E, Lee TT, Strong L, Tompkins RG, Yarmush ML Sn-chlorin e6 antibacterial immunoconjugates. An in vitro and in vivo analysis. J Immunol Methods. 1992;156(1):85-99 - PMID: 1431166 - DOI: 10.1016/0022-1759(92)90014-k

  • Tompkins RG Fulminant hepatic failure treated with anti-endotoxin antibody. Crit Care Med. 1992;20(11):1507 - PMID: 1424690 - DOI: 10.1097/00003246-199211000-00004

  • Yarmush ML, Toner M, Dunn JC, Rotem A, Hubel A, Tompkins RG Hepatic tissue engineering. Development of critical technologies. Ann N Y Acad Sci. 1992;665:238-52 - PMID: 1416606 - DOI: 10.1111/j.1749-6632.1992.tb42588.x

  • Cannon JG, Friedberg JS, Gelfand JA, Tompkins RG, Burke JF, Dinarello CA Circulating interleukin-1 beta and tumor necrosis factor-alpha concentrations after burn injury in humans. Crit Care Med. 1992;20(10):1414-9 - PMID: 1395662 - DOI: 10.1097/00003246-199210000-00009

  • Bader A, Borel Rinkes IH, Closs EI, Ryan CM, Toner M, Cunningham JM, Tompkins RG, Yarmush ML A stable long-term hepatocyte culture system for studies of physiologic processes: cytokine stimulation of the acute phase response in rat and human hepatocytes. Biotechnol Prog. 1992;8(3):219-25 - PMID: 1368259 - DOI: 10.1021/bp00015a007

  • Borel Rinkes IH, Toner M, Ezzell RM, Tompkins RG, Yarmush ML Effects of dimethyl sulfoxide on cultured rat hepatocytes in sandwich configuration. Cryobiology. 1992;29(4):443-53 - PMID: 1395682 - DOI: 10.1016/0011-2240(92)90047-6

  • Lee J, Morgan JR, Tompkins RG, Yarmush ML The importance of proline on long-term hepatocyte function in a collagen gel sandwich configuration: regulation of protein secretion. Biotechnol Bioeng. 1992;40(2):298-305 - PMID: 18601116 - DOI: 10.1002/bit.260400214

  • Carter EA, Gonnella A, Tompkins RG Increased transcellular permeability of rat small intestine after thermal injury. Burns. 1992;18(2):117-20 - PMID: 1590925 - DOI: 10.1016/0305-4179(92)90007-h

  • Ryan CM, Yarmush ML, Tompkins RG Separation and quantitation of polyethylene glycols 400 and 3350 from human urine by high-performance liquid chromatography. J Pharm Sci. 1992;81(4):350-2 - PMID: 1501072 - DOI: 10.1002/jps.2600810412

  • Rakestraw SL, Ford WE, Tompkins RG, Rodgers MA, Thorpe WP, Yarmush ML Antibody-targeted photolysis: in vitro immunological, photophysical, and cytotoxic properties of monoclonal antibody-dextran-Sn(IV) chlorin e6 immunoconjugates. Biotechnol Prog. 1992;8(1):30-9 - PMID: 1371392 - DOI: 10.1021/bp00013a006

  • Hubel A, Toner M, Cravalho EG, Yarmush ML, Tompkins RG Intracellular ice formation during the freezing of hepatocytes cultured in a double collagen gel. Biotechnol Prog. 1992;7(6):554-9 - PMID: 1367755 - DOI: 10.1021/bp00012a011

  • Dunn JC, Tompkins RG, Yarmush ML Hepatocytes in collagen sandwich: evidence for transcriptional and translational regulation. J Cell Biol. 1992;116(4):1043-53 - PMID: 1734019 - PMCID: PMC2289333 - DOI: 10.1083/jcb.116.4.1043

  • Shockley TR, Lin K, Sung C, Nagy JA, Tompkins RG, Dedrick RL, Dvorak HF, Yarmush ML A quantitative analysis of tumor specific monoclonal antibody uptake by human melanoma xenografts: effects of antibody immunological properties and tumor antigen expression levels. Cancer Res. 1992;52(2):357-66 - PMID: 1728407

  • Shockley TR, Lin K, Nagy JA, Tompkins RG, Yarmush ML, Dvorak HF Spatial distribution of tumor-specific monoclonal antibodies in human melanoma xenografts. Cancer Res. 1992;52(2):367-76 - PMID: 1728408

  • Borel Rinkes IH, Mehmet T, Sheehan SJ, Tompkins RG, Yarmush ML LONG-TERM FUNCTIONAL RECOVERY OF HEPATOCYTES AFTER CRYOPRESERVATION IN A THREE-DIMENSIONAL CULTURE CONFIGURATION. Cell Transplant. 1992;1(4):281-292 - PMID: 28148377

  • Dunn JC, Tompkins RG, Yarmush ML Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration. Biotechnol Prog. 1991;7(3):237-45 - PMID: 1367596 - DOI: 10.1021/bp00009a007

  • Harris CL, Toner M, Hubel A, Cravalho EG, Yarmush ML, Tompkins RG Cryopreservation of isolated hepatocytes: intracellular ice formation under various chemical and physical conditions. Cryobiology. 1991;28(5):436-44 - PMID: 1752131 - DOI: 10.1016/0011-2240(91)90052-p

  • Tompkins RG, Fischman AJ, Yarmush ML Imaging infections with antibodies. A method to localize occult infections. Chest. 1991;100(3 Suppl):169S-172S - PMID: 1909225

  • Rakestraw SL, Tompkins RG, Yarmush ML Preparation and characterization of immunoconjugates for antibody-targeted photolysis. Bioconjug Chem. 1991;1(3):212-21 - PMID: 1710935 - DOI: 10.1021/bc00003a006

  • Friedberg JS, Tompkins RG, Rakestraw SL, Warren SW, Fischman AJ, Yarmush ML Antibody-targeted photolysis. Bacteriocidal effects of Sn (IV) chlorin e6-dextran-monoclonal antibody conjugates. Ann N Y Acad Sci. 1991;618:383-93 - PMID: 1706578 - DOI: 10.1111/j.1749-6632.1991.tb27258.x

  • Shockley TR, Lin K, Nagy JA, Tompkins RG, Dvorak HF, Yarmush ML Penetration of tumor tissue by antibodies and other immunoproteins. Ann N Y Acad Sci. 1991;618:367-82 - PMID: 2006796 - DOI: 10.1111/j.1749-6632.1991.tb27257.x

  • Tompkins RG Quantitative analysis of blood vessel permeability of squirrel monkeys. Am J Physiol. 1991;260(4 Pt 2):H1194-204 - PMID: 2012223 - DOI: 10.1152/ajpheart.1991.260.4.H1194

  • Tompkins RG, Burke JF Progress in burn treatment and the use of artificial skin. World J Surg. 1991;14(6):819-24 - PMID: 2256353 - DOI: 10.1007/BF01670529

  • Shockley TR, Mandeville JT, Tompkins RG, Yarmush ML Equilibrium binding characteristics of monoclonal antibodies recognizing melanoma cell surface antigens. Hybridoma. 1990;9(6):527-44 - PMID: 2076895 - DOI: 10.1089/hyb.1990.9.527

  • Koebe HG, Dunn JC, Toner M, Sterling LM, Hubel A, Cravalho EG, Yarmush ML, Tompkins RG A new approach to the cryopreservation of hepatocytes in a sandwich culture configuration. Cryobiology. 1990;27(5):576-84 - PMID: 2249459 - DOI: 10.1016/0011-2240(90)90045-6

  • Morrel EM, Tompkins RG, Fischman AJ, Wilkinson RA, Yarmush ML Imaging infections with antibodies. A quantitative autoradiographic analysis. J Immunol Methods. 1990;130(1):39-48 - PMID: 2193059 - DOI: 10.1016/0022-1759(90)90297-9

  • Carter EA, Hatz RA, Yarmush ML, Tompkins RG Injury-induced inhibition of small intestinal protein and nucleic acid synthesis. Gastroenterology. 1990;98(6):1445-51 - PMID: 1692545 - DOI: 10.1016/0016-5085(90)91074-g

  • Rakestraw SL, Tompkins RG, Yarmush ML Antibody-targeted photolysis: in vitro studies with Sn(IV) chlorin e6 covalently bound to monoclonal antibodies using a modified dextran carrier. Proc Natl Acad Sci U S A. 1990;87(11):4217-21 - PMID: 1693435 - PMCID: PMC54079 - DOI: 10.1073/pnas.87.11.4217

  • Carter EA, Tompkins RG, Schiffrin E, Burke JF Cutaneous thermal injury alters macromolecular permeability of rat small intestine. Surgery. 1990;107(3):335-41 - PMID: 2309150

  • Cannon JG, Tompkins RG, Gelfand JA, Michie HR, Stanford GG, van der Meer JW, Endres S, Lonnemann G, Corsetti J, Chernow B Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever. J Infect Dis. 1990;161(1):79-84 - PMID: 2295861 - DOI: 10.1093/infdis/161.1.79

  • Morrell EM, Tompkins RG, Fischman AJ, Wilkinson RA, Burke JF, Rubin RH, Strauss HW, Yarmush ML Autoradiographic method for quantitation of radiolabeled proteins in tissues using indium-111. J Nucl Med. 1989;30(9):1538-45 - PMID: 2504892

  • Tompkins RG, Hilton JF, Burke JF, Schoenfeld DA, Hegarty MT, Bondoc CC, Quinby WC, Behringer GE, Ackroyd FW Increased survival after massive thermal injuries in adults: preliminary report using artificial skin. Crit Care Med. 1989;17(8):734-40 - PMID: 2546715 - DOI: 10.1097/00003246-198908000-00003

  • Tompkins RG, Yarmush ML, Schnitzer JJ, Colton CK, Smith KA, Stemerman MB Low-density lipoprotein transport in blood vessel walls of squirrel monkeys. Am J Physiol. 1989;257(2 Pt 2):H452-64 - PMID: 2764130 - DOI: 10.1152/ajpheart.1989.257.2.H452

  • Tompkins RG, Schnitzer JJ, Yarmush ML Macromolecular transport within heart valves. Circ Res. 1989;64(6):1213-23 - PMID: 2720921 - DOI: 10.1161/01.res.64.6.1213

  • Moncure AC, Tompkins RG, Athanasoulis CA, Welch CE Occult gastrointestinal bleeding: newer techniques and diagnosis and therapy. Adv Surg. 1989;22:141-77 - PMID: 2645744

  • Carter EA, Kirkham SE, Tompkins RG, Burke JF Inhibition of in vivo DNA synthesis in regenerating rat liver following thermal injury. Biochem Biophys Res Commun. 1989;160(1):196-201 - PMID: 2785385 - DOI: 10.1016/0006-291x(89)91640-9

  • Carter EA, Tompkins RG, Burke JF Hepatic and intestinal blood flow following thermal injury. J Burn Care Rehabil. 1989;9(4):347-50 - PMID: 3220848 - DOI: 10.1097/00004630-198807000-00006

  • Dunn JC, Yarmush ML, Koebe HG, Tompkins RG Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration. FASEB J. 1989;3(2):174-7 - PMID: 2914628 - DOI: 10.1096/fasebj.3.2.2914628

  • Tompkins RG, Remensnyder JP, Burke JF, Tompkins DM, Hilton JF, Schoenfeld DA, Behringer GE, Bondoc CC, Briggs SE, Quinby WC Significant reductions in mortality for children with burn injuries through the use of prompt eschar excision. Ann Surg. 1988;208(5):577-85 - PMID: 3190284 - PMCID: PMC1493782 - DOI: 10.1097/00000658-198811000-00006

  • Carter EA, Tompkins RG, Yarmush ML, Walker WA, Burke JF Redistribution of blood flow after thermal injury and hemorrhagic shock. J Appl Physiol. 1988;65(4):1782-8 - PMID: 3182540 - DOI: 10.1152/jappl.1988.65.4.1782

  • Tompkins RG, Schnitzer JJ, Yarmush ML, Colton CK, Smith KA Measurement of 125I-low density lipoprotein uptake in selected tissues of the squirrel monkey by quantitative autoradiography. Am J Pathol. 1988;132(3):526-42 - PMID: 3414782 - PMCID: PMC1880767

  • Tompkins RG, McCabe CJ, Burke JF, Keating MA, Wright CD Rectal necrosis after pelvic crush injury. J Trauma. 1988;28(5):697-9 - PMID: 3367418 - DOI: 10.1097/00005373-198805000-00027

  • Ch SW, Carter EA, Tompkins RG, Burke JF Increase of sialyltransferase activity in the small intestine following thermal injury in rats. Biochem Biophys Res Commun. 1988;153(1):377-81 - PMID: 3259879 - DOI: 10.1016/s0006-291x(88)81234-8

  • Tompkins RG, Carter EA, Carlson JD, Yarmush ML Enzymatic function of alginate immobilized rat hepatocytes. Biotechnol Bioeng. 1988;31(1):11-8 - PMID: 18581557 - DOI: 10.1002/bit.260310103

  • Tompkins RG, Burke JF Burn therapy 1985: acute management. Intensive Care Med. 1986;12(4):289-95 - PMID: 3531277 - DOI: 10.1007/BF00261738

  • Tompkins RG, Burke JF, Schoenfeld DA, Bondoc CC, Quinby WC, Behringer GC, Ackroyd FW Prompt eschar excision: a treatment system contributing to reduced burn mortality. A statistical evaluation of burn care at the Massachusetts General Hospital (1974-1984). Ann Surg. 1986;204(3):272-81 - PMID: 3753058 - PMCID: PMC1251276 - DOI: 10.1097/00000658-198609000-00006

  • Tompkins RG, Warshaw AL Improved management of the perineal wound after proctectomy. Ann Surg. 1985;202(6):760-5 - PMID: 4073988 - PMCID: PMC1251011 - DOI: 10.1097/00000658-198512000-00016

  • Porter JR, Kastin AJ, Pelle-Day G, Tompkins RG Regional in vitro uptake of a synthetic 3H-labeled-melanin into rat brain. Brain Res Bull. 1978;2(6):401-4 - PMID: 606338 - DOI: 10.1016/0361-9230(77)90049-1

  • Kastin AJ, Kuzemchak B, Tompkins RG, Schally AV, Miller MC Melanin in the rat brain. Brain Res Bull. 1977;1(6):567-72 - PMID: 1021212 - DOI: 10.1016/0361-9230(76)90083-6

  • LYONS WS, TOMPKINS RG, KIRKLIN JW, WOOD EH Early and late hemodynamic effects of mitral commissurotomy. J Lab Clin Med. 1959;53(4):499-516 - PMID: 13654887

  • WARNER HR, SWAN HJ, CONNOLLY DC, TOMPKINS RG, WOOD EH Quantitation of beat-to-beat changes in stroke volume from the aortic pulse contour in man. J Appl Physiol. 1953;5(9):495-507 - PMID: 13034677 - DOI: 10.1152/jappl.1953.5.9.495

  • KIRKLIN JW, OPENSHAW CR, TOMPKINS RG Surgical treatment of infundibular stenosis with intact ventricular septum. Ann Surg. 1953;137(2):228-31 - PMID: 13017523 - PMCID: PMC1802459 - DOI: 10.1097/00000658-195302000-00013

  • CONNOLLY DC, TOMPKINS RG, LEV R, KIRKLIN JW, WOOD EH Pulmonary artery wedge pressures in mitral valve disease; relationship to left atrial pressures. Proc Staff Meet Mayo Clin. 1953;28(3):72-8 - PMID: 13014128