Tompkins, Ron

Phone: 617-726-3447


Ron Tompkins graduated Summa Cum Laude from Tulane University Medical School and holds a doctorate in chemical and biomedical engineering from the Massachusetts Institute of Technology.

Dr. Tompkins is the Chief of Burns Service at the Massachusetts General Hospital, is the Sumner M. Redstone Professor of Surgery at Harvard Medical School, and serves as the Chief of Staff of Shriners Hospital for Children in Boston.

Dr. Tompkins’ primary research interests are in physiology of inflammation and burn healing.

Selected Publications (from total of 401)


Frydman GH, Metcalf Pate KA, Marini RP, de Laforcade AM, Bosch I, Bakthavatchalu V, Muthupalani S, Swennes AG, Lyons CE, Tompkins RG, Fox JG
Adult-onset, chronic, cyclic thrombocytopenia in a Rhesus macaque (Macaca mulatta) after dengue virus vaccination and viral challenge.
Vet Clin Pathol. 2017;:ePub - PMID: 28518476
Khan MA, Khan MF, Kashiwagi S, Kem WR, Yasuhara S, Kaneki M, Tompkins RG, Martyn JA
An Alpha7 Nicotinic Acetylcholine Receptor Agonist (GTS-21) Promotes C2C12 Myonuclear Accretion in Association with Release of Interleukin-6 (IL-6) and Improves Survival in Burned Mice.
Shock. 2017;:ePub - PMID: 28282360
Frydman GH, Marini RP, Bakthavatchalu V, Biddle KE, Muthupalani S, Vanderburg CR, Lai B, Bendapudi PK, Tompkins RG, Fox JG
Local and Systemic Changes Associated with Long-term, Percutaneous, Static Implantation of Titanium Alloys in Rhesus Macaques (Macaca mulatta).
Comp Med. 2017;67(2):165-175 - PMID: 28381317 - PMCID: PMC5402736
Nakazawa H, Chang K, Shinozaki S, Yasukawa T, Ishimaru K, Yasuhara S, Yu YM, Martyn JA, Tompkins RG, Shimokado K, Kaneki M
iNOS as a Driver of Inflammation and Apoptosis in Mouse Skeletal Muscle after Burn Injury: Possible Involvement of Sirt1 S-Nitrosylation-Mediated Acetylation of p65 NF-?B and p53.
PLoS One. 2017;12(1):e0170391 - PMID: 28099528 - PMCID: PMC5242494
Mason SA, Nathens AB, Finnerty CC, Gamelli RL, Gibran NS, Arnoldo BD, Tompkins RG, Herndon DN, Jeschke MG,
Hold the Pendulum: Rates of Acute Kidney Injury are Increased in Patients Who Receive Resuscitation Volumes Less than Predicted by the Parkland Equation.
Ann Surg. 2016;264(6):1142-1147 - PMID: 27828823 - PMCID: PMC5111808
Li P, Tompkins RG, Xiao W,
KERIS: kaleidoscope of gene responses to inflammation between species.
Nucleic Acids Res. 2016;45(D1):D908-D914 - PMID: 27789704 - PMCID: PMC5210651
Tsurumi A, Que YA, Ryan CM, Tompkins RG, Rahme LG
TNF-?/IL-10 Ratio Correlates with Burn Severity and May Serve as a Risk Predictor of Increased Susceptibility to Infections.
Front Public Health. 2016;4:216 - PMID: 27761434 - PMCID: PMC5050217
Porter C, Tompkins RG, Finnerty CC, Sidossis LS, Suman OE, Herndon DN
The metabolic stress response to burn trauma: current understanding and therapies.
Lancet. 2016;388(10052):1417-1426 - PMID: 27707498
Frydman GH, Le A, Ellett F, Jorgensen J, Fox JG, Tompkins RG, Irimia D
Changes in neutrophil migration patterns upon contact with platelets in a microfluidic assay.
J Leukoc Biol. 2016;101(3):797-806 - PMID: 27630219 - PMCID: PMC5295852
Kashiwagi S, Khan MA, Yasuhara S, Goto T, Tompkins RG, Kaneki M, Martyn JA
Prevention of Burn-Induced Inflammatory Responses and Muscle Wasting By GTS-21, A Specific Agonist for ?7 Nicotinic Acetylcholine Receptors.
Shock. 2016;47(1):61-69 - PMID: 27529131 - PMCID: PMC5167674
Syrkina O, Hales CH, Bonab AA, Hamrahi V, Paul K, Jung WJ, Tompkins RG, Fischman AJ, Carter EA
Molecular Imaging of Smoke-Induced Changes in Nuclear Factor-Kappa B Expression in Murine Tissues Including the Lung.
J Burn Care Res. 2016;37(6):335-342 - PMID: 27437954
Frydman GH, Bendapudi PK, Marini RP, Vanderburg CR, Tompkins RG, Fox JG
Coagulation Biomarkers in Healthy Chinese-Origin Rhesus Macaques (Macaca mulatta).
J Am Assoc Lab Anim Sci. 2016;55(3):252-9 - PMID: 27177557 - PMCID: PMC4865685
Ueki R, Liu L, Kashiwagi S, Kaneki M, Khan M, Hirose M, Tompkins RG, Martyn JA, Yasuhara S
Role of Elevated Fibrinogen in Burn-Induced Mitochondrial Dysfunction: Protective Effects of Glycyrrhizin.
Shock. 2016;46(4):382-9 - PMID: 27172157 - PMCID: PMC5026541
Kazis LE, Lee AF, Rose M, Liang MH, Li NC, Ren XS, Sheridan R, Gilroy-Lewis J, Stoddard F, Hinson M, Warden G, Stubbs K, Blakeney P, Meyer W, McCauley R, Herndon D, Palmieri T, Mooney K, Wood D, Pidcock F, Reilly D, Cullen M, Calvert C, Ryan CM, Schneider JC, Soley-Bori M, Tompkins RG
Recovery Curves for Pediatric Burn Survivors: Advances in Patient-Oriented Outcomes.
JAMA Pediatr. 2016;170(6):534-542 - PMID: 26953515
Ryan CM, Cartwright S, Schneider JC, Tompkins RG, Kazis LE
The burn outcome questionnaires: Patient and family reported outcome metrics for children of all ages.
Burns. 2016;42(5):1144-5 - PMID: 26803370