Todd ZR, Szostak JW, Sasselov DD Shielding from UV Photodamage: Implications for Surficial Origins of Life Chemistry on the Early Earth. ACS Earth Space Chem. 2021;5(2):239-246 - PMID: 36317066 - PMCID: PMC9616438 - DOI: 10.1021/acsearthspacechem.0c00270

Duzdevich D, Carr CE, Ding D, Zhang SJ, Walton TS, Szostak JW Competition between bridged dinucleotides and activated mononucleotides determines the error frequency of nonenzymatic RNA primer extension. Nucleic Acids Res. 2021;49(7):3681-3691 - PMID: 33744957 - PMCID: PMC8053118 - DOI: 10.1093/nar/gkab173

Kim SC, O'Flaherty DK, Giurgiu C, Zhou L, Szostak JW The Emergence of RNA from the Heterogeneous Products of Prebiotic Nucleotide Synthesis. J Am Chem Soc. 2021;143(9):3267-3279 - PMID: 33636080 - DOI: 10.1021/jacs.0c12955

Mojarro A, Jin L, Szostak JW, Head JW, Zuber MT In search of the RNA world on Mars. Geobiology. 2021;19(3):307-321 - PMID: 33565260 - PMCID: PMC8248371 - DOI: 10.1111/gbi.12433

Radakovic A, Wright TH, Lelyveld VS, Szostak JW A Potential Role for Aminoacylation in Primordial RNA Copying Chemistry. Biochemistry. 2021;60(6):477-488 - PMID: 33523633 - PMCID: PMC9634692 - DOI: 10.1021/acs.biochem.0c00943

Zhang W, Kim SC, Tam CP, Lelyveld VS, Bala S, Chaput JC, Szostak JW Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization. Nucleic Acids Res. 2021;49(2):646-656 - PMID: 33347562 - PMCID: PMC7826252 - DOI: 10.1093/nar/gkaa1215

Zhou L, Ding D, Szostak JW The Virtual Circular Genome Model for Primordial RNA Replication. RNA. 2021;27(1):1-11 - PMID: 33028653 - PMCID: PMC7749632 - DOI: 10.1261/rna.077693.120