• Duzdevich D, Carr CE, Ding D, Zhang SJ, Walton TS, Szostak JW Competition between bridged dinucleotides and activated mononucleotides determines the error frequency of nonenzymatic RNA primer extension. Nucleic Acids Res. 2021;49(7):3681-3691 - PMID: 33744957 - PMCID: PMC8053118 - DOI: 10.1093/nar/gkab173

  • Kim SC, O'Flaherty DK, Giurgiu C, Zhou L, Szostak JW The Emergence of RNA from the Heterogeneous Products of Prebiotic Nucleotide Synthesis. J Am Chem Soc. 2021;143(9):3267-3279 - PMID: 33636080 - DOI: 10.1021/jacs.0c12955

  • Mojarro A, Jin L, Szostak JW, Head JW, Zuber MT In search of the RNA world on Mars. Geobiology. 2021;19(3):307-321 - PMID: 33565260 - PMCID: PMC8248371 - DOI: 10.1111/gbi.12433

  • Radakovic A, Wright TH, Lelyveld VS, Szostak JW A Potential Role for Aminoacylation in Primordial RNA Copying Chemistry. Biochemistry. 2021;60(6):477-488 - PMID: 33523633 - DOI: 10.1021/acs.biochem.0c00943

  • Zhang W, Kim SC, Tam CP, Lelyveld VS, Bala S, Chaput JC, Szostak JW Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization. Nucleic Acids Res. 2021;49(2):646-656 - PMID: 33347562 - PMCID: PMC7826252 - DOI: 10.1093/nar/gkaa1215

  • Strom KR, Szostak JW Solid-Phase Synthesis of Sequence-Defined Informational Oligomers. J Org Chem. 2020;85(21):13929-13938 - PMID: 33064001 - DOI: 10.1021/acs.joc.0c01977

  • Zhou L, Ding D, Szostak JW The Virtual Circular Genome Model for Primordial RNA Replication. RNA. 2021;27(1):1-11 - PMID: 33028653 - PMCID: PMC7749632 - DOI: 10.1261/rna.077693.120

  • O'Flaherty DK, Zhou L, Szostak JW Nonenzymatic RNA-templated Synthesis of N3'→P5' Phosphoramidate DNA. Bio Protoc. 2020;10(17):e3734 - PMID: 33659395 - PMCID: PMC7842504 - DOI: 10.21769/BioProtoc.3734

  • Zhang SJ, Duzdevich D, Szostak JW Potentially Prebiotic Activation Chemistry Compatible with Nonenzymatic RNA Copying. J Am Chem Soc. 2020;142(35):14810-14813 - PMID: 32794700 - DOI: 10.1021/jacs.0c05300

  • Zhou L, O'Flaherty DK, Szostak JW Assembly of a ribozyme ligase from short oligomers by nonenzymatic ligation. J Am Chem Soc. 2020;142(37):15961-15965 - PMID: 32820909 - DOI: 10.1021/jacs.0c06722

  • Zhou L, O'Flaherty DK, Szostak JW Template-directed copying of RNA by non-enzymatic ligation. Angew Chem Int Ed Engl. 2020;59(36):15682-15687 - PMID: 32558121 - PMCID: PMC7496532 - DOI: 10.1002/anie.202004934

  • Kindt JT, Szostak JW, Wang A Bulk Self-Assembly of Giant, Unilamellar Vesicles. ACS Nano. 2020;14(11):14627-14634 - PMID: 32602696 - PMCID: PMC8172239 - DOI: 10.1021/acsnano.0c03125

  • Duzdevich D, Carr CE, Szostak JW Deep sequencing of non-enzymatic RNA primer extension. Nucleic Acids Res. 2020;48(12):e70 - PMID: 32427335 - PMCID: PMC7337528 - DOI: 10.1093/nar/gkaa400

  • Todd ZR, Fahrenbach AC, Ranjan S, Magnani CJ, Szostak JW, Sasselov DD Ultraviolet-Driven Deamination of Cytidine Ribonucleotides Under Planetary Conditions. Astrobiology. 2020;20(7):878-888 - PMID: 32267736 - DOI: 10.1089/ast.2019.2182

  • Lelyveld VS, Zhang W, Szostak JW Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase. Proc Natl Acad Sci U S A. 2020;117(13):7276-7283 - PMID: 32188786 - PMCID: PMC7132125 - DOI: 10.1073/pnas.1922400117

  • Walton T, DasGupta S, Duzdevich D, Oh SS, Szostak JW In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole-activated substrates. Proc Natl Acad Sci U S A. 2020;117(11):5741-5748 - PMID: 32123094 - PMCID: PMC7084097 - DOI: 10.1073/pnas.1914367117

  • Kim SC, Zhou L, Zhang W, O'Flaherty DK, Rondo-Brovetto V, Szostak JW A model for the emergence of RNA from a prebiotically plausible mixture of ribonucleotides, arabinonucleotides and 2'-deoxynucleotides. J Am Chem Soc. 2020;142(5):2317-2326 - PMID: 31913615 - PMCID: PMC7577264 - DOI: 10.1021/jacs.9b11239

  • Zhou L, Kim S, Ho KH, O'Flaherty DK, Giurgiu C, Wright TH, Szostak JW Non-enzymatic primer extension with strand displacement. Elife. 2019;8:ePub - PMID: 31702557 - PMCID: PMC6872209 - DOI: 10.7554/eLife.51888

  • Wang A, Szostak JW Lipid constituents of model protocell membranes. Emerg Top Life Sci. 2019;3(5):537-542 - PMID: 33523161 - DOI: 10.1042/ETLS20190021

  • Wright TH, Giurgiu C, Zhang W, Radakovic A, O'Flaherty DK, Zhou L, Szostak JW Prebiotically Plausible 'Patching' of RNA Backbone Cleavage Through a 3'-5' Pyrophosphate Linkage. J Am Chem Soc. 2019;141(45):18104-18112 - PMID: 31651170 - PMCID: PMC7577263 - DOI: 10.1021/jacs.9b08237

  • Lelyveld VS, O'Flaherty DK, Zhou L, Izgu EC, Szostak JW DNA polymerase activity on synthetic N3'→P5' phosphoramidate DNA templates. Nucleic Acids Res. 2019;47(17):8941-8949 - PMID: 31428779 - PMCID: PMC6755091 - DOI: 10.1093/nar/gkz707

  • Todd ZR, Szabla R, Szostak JW, Sasselov DD UV photostability of three 2-aminoazoles with key roles in prebiotic chemistry on the early earth. Chem Commun (Camb). 2019;55(70):10388-10391 - PMID: 31380533 - DOI: 10.1039/c9cc05265h

  • Zhang W, Pal A, Ricardo A, Szostak JW Template-directed Nonenzymatic Primer Extension Using 2-methylimidazole-activated Morpholino Derivatives of Guanosine and Cytidine. J Am Chem Soc. 2019;141(30):12159-12166 - PMID: 31298852 - PMCID: PMC7547883 - DOI: 10.1021/jacs.9b06453

  • O'Flaherty DK, Zhou L, Szostak JW Nonenzymatic template-directed synthesis of mixed-sequence 3'-NP-DNA up to 25 nucleotides long inside model protocells. J Am Chem Soc. 2019;141(26):10481-10488 - PMID: 31180644 - PMCID: PMC7547854 - DOI: 10.1021/jacs.9b04858

  • Walton T, Zhang W, Li L, Tam CP, Szostak JW The mechanism of nonenzymatic template copying with imidazole-activated nucleotides. Angew Chem Int Ed Engl. 2019;58(32):10812-10819 - PMID: 30908802 - DOI: 10.1002/anie.201902050

  • Strom KR, Szostak JW, Prywes N Transfer of Sequence Information and Replication of Diimine Duplexes. J Org Chem. 2019;84(7):3754-3761 - PMID: 30855962 - PMCID: PMC7547894 - DOI: 10.1021/acs.joc.9b00095

  • Matsushita-Ishiodori Y, Hanczyc MM, Wang A, Szostak JW, Yomo T Using Imaging Flow Cytometry to Quantify and Optimize Giant Vesicle Production by Water-in-oil Emulsion Transfer Methods. Langmuir. 2019;35(6):2375-2382 - PMID: 30645943 - DOI: 10.1021/acs.langmuir.8b03635

  • Wang A, Chan Miller C, Szostak JW Core-Shell Modeling of Light Scattering by Vesicles: Effect of Size, Contents, and Lamellarity. Biophys J. 2019;116(4):659-669 - PMID: 30686489 - PMCID: PMC6382849 - DOI: 10.1016/j.bpj.2019.01.006

  • Kim SC, O'Flaherty DK, Zhou L, Lelyveld VS, Szostak JW Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA. Proc Natl Acad Sci U S A. 2018;115(52):13318-13323 - PMID: 30509978 - PMCID: PMC6310819 - DOI: 10.1073/pnas.1814367115

  • Jin L, Engelhart AE, Zhang W, Adamala KP, Szostak JW Catalysis of Template-directed Nonenzymatic RNA Copying by Iron (II). J Am Chem Soc. 2018;140(44):15016-15021 - PMID: 30335371 - PMCID: PMC7547886 - DOI: 10.1021/jacs.8b09617

  • Joyce GF, Szostak JW Protocells and RNA Self-Replication. Cold Spring Harb Perspect Biol. 2018;10(9):ePub - PMID: 30181195 - PMCID: PMC6120706 - DOI: 10.1101/cshperspect.a034801

  • Zhang W, Walton T, Li L, Szostak JW Crystallographic observation of nonenzymatic RNA primer extension. Elife. 2018;7:ePub - PMID: 29851379 - PMCID: PMC5980232 - DOI: 10.7554/eLife.36422

  • O'Flaherty DK, Kamat NP, Mirza FN, Li L, Prywes N, Szostak JW Copying of mixed sequence RNA templates inside model protocells. J Am Chem Soc. 2018;140(15):5171-5178 - PMID: 29608310 - PMCID: PMC7547884 - DOI: 10.1021/jacs.8b00639

  • Jin L, Kamat NP, Jena S, Szostak JW Fatty Acid/Phospholipid Blended Membranes: A Potential Intermediate State in Protocellular Evolution. Small. 2018;14(15):e1704077 - PMID: 29479815 - PMCID: PMC6278924 - DOI: 10.1002/smll.201704077

  • Jin L, Engelhart AE, Adamala KP, Szostak JW Preparation, Purification, and Use of Fatty Acid-containing Liposomes. J Vis Exp. 2018;(132):ePub - PMID: 29553563 - PMCID: PMC5912384 - DOI: 10.3791/57324

  • Zhang W, Tam CP, Zhou L, Oh SS, Wang J, Szostak JW A structural rationale for the enhanced catalysis of nonenzymatic RNA primer extension by a downstream oligonucleotide. J Am Chem Soc. 2018;140(8):2829-2840 - PMID: 29411978 - PMCID: PMC6326529 - DOI: 10.1021/jacs.7b11750

  • Todd ZR, Fahrenbach AC, Magnani CJ, Ranjan S, Björkbom A, Szostak JW, Sasselov DD Solvated-electron production using cyanocuprates is compatible with the UV-environment on a Hadean-Archaean Earth. Chem Commun (Camb). 2018;54(9):1121-1124 - PMID: 29334083 - DOI: 10.1039/c7cc07748c

  • Giurgiu C, Li L, O'Flaherty DK, Tam CP, Szostak JW A Mechanistic Explanation for the Regioselectivity of Nonenzymatic RNA Primer Extension. J Am Chem Soc. 2017;139(46):16741-16747 - PMID: 29112424 - PMCID: PMC6326530 - DOI: 10.1021/jacs.7b08784

  • Jia TZ, Fahrenbach AC, Kamat NP, Adamala KP, Szostak JW Retraction: Oligoarginine peptides slow strand annealing and assist non-enzymatic RNA replication. Nat Chem. 2017;9(12):1286 - PMID: 29168488 - PMCID: PMC7412977 - DOI: 10.1038/nchem.2885

  • Walton T, Szostak JW A kinetic model of nonenzymatic RNA polymerization by cytidine-5'-phosphoro-2-aminoimidazolide. Biochemistry. 2017;56(43):5739-5747 - PMID: 29022704 - PMCID: PMC6340129 - DOI: 10.1021/acs.biochem.7b00792

  • Bonfio C, Valer L, Scintilla S, Shah S, Evans DJ, Jin L, Szostak JW, Sasselov DD, Sutherland JD, Mansy SS UV-light-driven prebiotic synthesis of iron-sulfur clusters. Nat Chem. 2017;9(12):1229-1234 - PMID: 29168482 - PMCID: PMC5808832 - DOI: 10.1038/nchem.2817

  • Zhang W, Tam CP, Walton T, Fahrenbach AC, Birrane G, Szostak JW Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex. Proc Natl Acad Sci U S A. 2017;114(29):7659-7664 - PMID: 28673998 - PMCID: PMC5530681 - DOI: 10.1073/pnas.1704006114

  • Fahrenbach AC, Giurgiu C, Tam CP, Li L, Hongo Y, Aono M, Szostak JW Common and Potentially Prebiotic Origin for Precursors of Nucleotide Synthesis and Activation. J Am Chem Soc. 2017;139(26):8780-8783 - PMID: 28640999 - PMCID: PMC6326526 - DOI: 10.1021/jacs.7b01562

  • Stairs S, Nikmal A, Bucar DK, Zheng SL, Szostak JW, Powner MW Divergent prebiotic synthesis of pyrimidine and 8-oxo-purine ribonucleotides. Nat Commun. 2017;8:15270 - PMID: 28524845 - PMCID: PMC5454461 - DOI: 10.1038/ncomms15270

  • Szostak JW The Narrow Road to the Deep Past. Angew Chem Int Ed Engl. 2017;56(37):11037-11043 - PMID: 28514493 - DOI: 10.1002/anie.201704048

  • Li L, Prywes N, Tam CP, O'Flaherty DK, Lelyveld VS, Izgu EC, Pal A, Szostak JW Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides. J Am Chem Soc. 2017;139(5):1810-1813 - PMID: 28117989 - PMCID: PMC6326525 - DOI: 10.1021/jacs.6b13148

  • Tam CP, Fahrenbach AC, Björkbom A, Prywes N, Izgu EC, Szostak JW Downstream Oligonucleotides Strongly Enhance the Affinity of GMP to RNA Primer-Template Complexes. J Am Chem Soc. 2017;139(2):571-574 - PMID: 28055190 - PMCID: PMC7547879 - DOI: 10.1021/jacs.6b09760

  • Izgu EC, Björkbom A, Kamat NP, Lelyveld VS, Zhang W, Jia TZ, Szostak JW N-Carboxyanhydride-Mediated Fatty Acylation of Amino Acids and Peptides for Functionalization of Protocell Membranes. J Am Chem Soc. 2016;138(51):16669-16676 - PMID: 27959544 - PMCID: PMC7547885 - DOI: 10.1021/jacs.6b08801

  • Zhang W, Tam CP, Wang J, Szostak JW Unusual Base-Pairing Interactions in Monomer-Template Complexes. ACS Cent Sci. 2016;2(12):916-926 - PMID: 28058281 - PMCID: PMC5200924 - DOI: 10.1021/acscentsci.6b00278

  • Pal A, Das RS, Zhang W, Lang M, McLaughlin LW, Szostak JW Effect of terminal 3'-hydroxymethyl modification of an RNA primer on nonenzymatic primer extension. Chem Commun (Camb). 2016;52(80):11905-11907 - PMID: 27722518 - DOI: 10.1039/c6cc06925h

  • Szostak JW On the origin of life. Medicina (B Aires). 2016;76(4):199-203 - PMID: 27576276

  • Walton T, Szostak JW A highly reactive imidazolium-bridged dinucleotide intermediate in nonenzymatic RNA primer extension. J Am Chem Soc. 2016;138(36):11996-2002 - PMID: 27552367 - PMCID: PMC6326528 - DOI: 10.1021/jacs.6b07977

  • Prywes N, Blain JC, Del Frate F, Szostak JW Nonenzymatic copying of RNA templates containing all four letters is catalyzed by activated oligonucleotides. Elife. 2016;5:ePub - PMID: 27351102 - PMCID: PMC4959843 - DOI: 10.7554/eLife.17756

  • Jia TZ, Fahrenbach AC, Kamat NP, Adamala KP, Szostak JW Oligoarginine peptides slow strand annealing and assist non-enzymatic RNA replication. Nat Chem. 2016;8(10):915-21 - PMID: 27657866 - PMCID: PMC5061144 - DOI: 10.1038/nchem.2551

  • Prywes N, Michaels YS, Pal A, Oh SS, Szostak JW Thiolated uridine substrates and templates improve the rate and fidelity of ribozyme-catalyzed RNA copying. Chem Commun (Camb). 2016;52(39):6529-32 - PMID: 27109314 - DOI: 10.1039/c6cc02692c

  • Adamala KP, Engelhart AE, Szostak JW Collaboration between primitive cell membranes and soluble catalysts. Nat Commun. 2016;7:11041 - PMID: 26996603 - PMCID: PMC4802160 - DOI: 10.1038/ncomms11041

  • Li L, Lelyveld VS, Prywes N, Szostak JW Experimental and computational evidence for a loose transition state in phosphoroimidazolide hydrolysis. J Am Chem Soc. 2016;138(12):3986-9 - PMID: 26974265 - PMCID: PMC7547882 - DOI: 10.1021/jacs.6b00784

  • Engelhart AE, Adamala KP, Szostak JW A simple physical mechanism enables homeostasis in primitive cells. Nat Chem. 2016;8(5):448-53 - PMID: 27102678 - PMCID: PMC4929987 - DOI: 10.1038/nchem.2475

  • Izgu EC, Oh SS, Szostak JW Synthesis of activated 3'-amino-3'-deoxy-2-thio-thymidine, a superior substrate for the nonenzymatic copying of nucleic acid templates. Chem Commun (Camb). 2016;52(18):3684-6 - PMID: 26857159 - DOI: 10.1039/c5cc10317g

  • Lelyveld VS, Bjorkbom A, Ransey E, Sliz P, Szostak JW Pinpointing RNA-protein crosslinks with site-specific stable isotope labeled oligonucleotides. J Am Chem Soc. 2015;137(49):15378-15381 - PMID: 26583201 - PMCID: PMC4697197 - DOI: 10.1021/jacs.5b10596

  • Bjorkbom A, Lelyveld VS, Zhang S, Zhang W, Tam CP, Blain JC, Szostak JW Bidirectional direct sequencing of non-canonical RNA by two-dimensional analysis of mass chromatograms. J Am Chem Soc. 2015;137(45):14430-8 - PMID: 26495937 - PMCID: PMC7547889 - DOI: 10.1021/jacs.5b09438

  • Larsen AT, Fahrenbach AC, Sheng J, Pian J, Szostak JW Thermodynamic insights into 2-thiouridine-enhanced RNA hybridization. Nucleic Acids Res. 2015;43(16):7675-87 - PMID: 26240387 - PMCID: PMC4652770 - DOI: 10.1093/nar/gkv761

  • Kamat NP, Tobé S, Hill IT, Szostak JW Electrostatic Localization of RNA to Protocell Membranes by Cationic Hydrophobic Peptides. Angew Chem Int Ed Engl. 2015;54(40):11735-11739 - PMID: 26223820 - PMCID: PMC4600236 - DOI: 10.1002/anie.201505742

  • Adamala K, Engelhart AE, Kamat NP, Jin L, Szostak JW Construction of a liposome dialyzer for the preparation of high-value, small-volume liposome formulations. Nat Protoc. 2015;10(6):927-938 - PMID: 26020615 - PMCID: PMC4982460 - DOI: 10.1038/nprot.2015.054

  • Izgu EC, Fahrenbach AC, Zhang N, Li L, Zhang W, Larsen A, Blain JC, Szostak JW Uncovering the Thermodynamics of Monomer Binding for RNA Replication. J Am Chem Soc. 2015;137(19):6373-82 - PMID: 25901790 - PMCID: PMC4984997 - DOI: 10.1021/jacs.5b02707

  • Heuberger BD, Pal A, Del Frate F, Topkar VV, Szostak JW Replacing Uridine with 2-Thio-Uridine Enhances the Rate and Fidelity of Nonenzymatic RNA Primer Extension. J Am Chem Soc. 2015;137(7):2769-75 - PMID: 25654265 - PMCID: PMC4985000 - DOI: 10.1021/jacs.5b00445

  • Adamala K, Engelhart AE, Szostak JW Generation of functional RNAs from inactive oligonucleotide complexes by non-enzymatic primer extension. J Am Chem Soc. 2015;137(1):483-9 - PMID: 25521912 - PMCID: PMC4984999 - DOI: 10.1021/ja511564d

  • Hentrich C, Szostak JW Controlled growth of filamentous fatty acid vesicles under flow. Langmuir. 2014;30(49):14916-25 - PMID: 25402759 - PMCID: PMC4985002 - DOI: 10.1021/la503933x

  • Budin I, Prwyes N, Zhang N, Szostak JW Chain-Length Heterogeneity Allows for the Assembly of Fatty Acid Vesicles in Dilute Solutions. Biophys J. 2014;107(7):1582-1590 - PMID: 25296310 - PMCID: PMC4190651 - DOI: 10.1016/j.bpj.2014.07.067

  • Sheng J, Larsen A, Heuberger BD, Blain JC, Szostak JW Crystal Structure Studies of RNA Duplexes Containing s2U:A and s2U:U Base Pairs. J Am Chem Soc. 2014;136(39):13916-24 - PMID: 25188906 - PMCID: PMC4183603 - DOI: 10.1021/ja508015a

  • Blain JC, Szostak JW Progress Toward Synthetic Cells. Annu Rev Biochem. 2014;83:615-40 - PMID: 24606140 - DOI: 10.1146/annurev-biochem-080411-124036

  • Jia TZ, Hentrich C, Szostak JW Rapid RNA Exchange in Aqueous Two-Phase System and Coacervate Droplets. Orig Life Evol Biosph. 2014;44(1):1-12 - PMID: 24577897 - PMCID: PMC4141154 - DOI: 10.1007/s11084-014-9355-8

  • Sheng J, Li L, Engelhart AE, Gan J, Wang J, Szostak JW Structural insights into the effects of 2'-5' linkages on the RNA duplex. Proc Natl Acad Sci U S A. 2014;111(8):3050-5 - PMID: 24516151 - PMCID: PMC3939906 - DOI: 10.1073/pnas.1317799111

  • Li L, Szostak JW The Free Energy Landscape of Pseudorotation in 3'-5' and 2'-5' Linked Nucleic Acids. J Am Chem Soc. 2014;136(7):2858-65 - PMID: 24499340 - PMCID: PMC3982932 - DOI: 10.1021/ja412079b

  • Blain JC, Ricardo A, Szostak JW Synthesis and Non-Enzymatic Template-Directed Polymerization of 2'-Amino-2'-Deoxythreose Nucleotides. J Am Chem Soc. 2014;136(5):2033-9 - PMID: 24409991 - PMCID: PMC4105081 - DOI: 10.1021/ja411950n

  • Zhu TF, Budin I, Szostak JW Preparation of Fatty Acid micelles. Methods Enzymol. 2013;533:283-8 - PMID: 24182934 - PMCID: PMC4310231 - DOI: 10.1016/B978-0-12-420067-8.00022-2

  • Zhu TF, Budin I, Szostak JW Vesicle Extrusion Through Polycarbonate Track-etched Membranes using a Hand-held Mini-extruder. Methods Enzymol. 2013;533:275-82 - PMID: 24182933 - PMCID: PMC4310236 - DOI: 10.1016/B978-0-12-420067-8.00021-0

  • Zhu TF, Budin I, Szostak JW Preparation of Fatty Acid or Phospholipid Vesicles by Thin-film Rehydration. Methods Enzymol. 2013;533:267-74 - PMID: 24182932 - PMCID: PMC4310237 - DOI: 10.1016/B978-0-12-420067-8.00020-9

  • Adamala K, Szostak JW Nonenzymatic template-directed RNA synthesis inside model protocells. Science. 2013;342(6162):1098-100 - PMID: 24288333 - PMCID: PMC4104020 - DOI: 10.1126/science.1241888

  • Zhang S, Blain JC, Zielinska D, Gryaznov SM, Szostak JW Fast and accurate nonenzymatic copying of an RNA-like synthetic genetic polymer. Proc Natl Acad Sci U S A. 2013;110(44):17732-7 - PMID: 24101473 - PMCID: PMC3816440 - DOI: 10.1073/pnas.1312329110

  • Adamala K, Szostak JW Competition between model protocells driven by an encapsulated catalyst. Nat Chem. 2013;5(7):634 - PMID: 23787756

  • Adamala K, Szostak JW Competition between model protocells driven by an encapsulated catalyst. Nat Chem. 2013;5(6):495-501 - PMID: 23695631 - PMCID: PMC4041014 - DOI: 10.1038/nchem.1650

  • Engelhart AE, Powner MW, Szostak JW Functional RNAs exhibit tolerance for non-heritable 2'-5' versus 3'-5' backbone heterogeneity. Nat Chem. 2013;5(5):390-4 - PMID: 23609089 - PMCID: PMC4088963 - DOI: 10.1038/nchem.1623

  • Zhang S, Zhang N, Blain JC, Szostak JW Synthesis of N3'-P5'-linked phosphoramidate DNA by nonenzymatic template-directed primer extension. J Am Chem Soc. 2013;135(2):924-32 - PMID: 23252395 - PMCID: PMC3548433 - DOI: 10.1021/ja311164j

  • Zhang S, Zhang N, Blain JC, Szostak JW Synthesis of N3´-P5´-Phosphoramidate DNA by Non-enzymatic Template-directed Primer Extension. J Am Chem Soc. 2013;135(2):924-32 - PMID: 23252395 - PMCID: PMC3548433 - DOI: 10.1021/ja311164j

  • Budin I, Debnath A, Szostak JW Concentration-driven growth of model protocell membranes. J Am Chem Soc. 2012;134(51):20812-9 - PMID: 23198690 - PMCID: PMC3530389 - DOI: 10.1021/ja310382d

  • Budin I, Debnath A, Szostak JW Concentration-driven growth of model protocell membranes. J Am Chem Soc. 2012;134(51):20812-9 - PMID: 23198690 - PMCID: PMC3530389 - DOI: 10.1021/ja310382d

  • Powner MW, Zheng SL, Szostak JW Multicomponent assembly of proposed DNA precursors in water. J Am Chem Soc. 2012;134(33):13889-95 - PMID: 22839703 - PMCID: PMC3424849 - DOI: 10.1021/ja306176n

  • Powner MW, Zheng SL, Szostak JW Multicomponent assembly of proposed DNA precursors in water. J Am Chem Soc. 2012;134(33):13889-95 - PMID: 22839703 - PMCID: PMC3424849 - DOI: 10.1021/ja306176n

  • Zhu TF, Adamala K, Zhang N, Szostak JW Photochemically driven redox chemistry induces protocell membrane pearling and division. Proc Natl Acad Sci U S A. 2012;109(25):9828-32 - PMID: 22665773 - PMCID: PMC3382484 - DOI: 10.1073/pnas.1203212109

  • Hofmann FT, Szostak JW, Seebeck FP In vitro selection of functional lantipeptides. J Am Chem Soc. 2012;134(19):8038-41 - PMID: 22545861 - PMCID: PMC3353655 - DOI: 10.1021/ja302082d

  • Guillen Schlippe YV, Hartman MC, Josephson K, Szostak JW In Vitro Selection of Highly Modified Cyclic Peptides That Act as Tight Binding Inhibitors. J Am Chem Soc. 2012;134(25):10469-77 - PMID: 22428867 - PMCID: PMC3384292 - DOI: 10.1021/ja301017y

  • Zhang N, Zhang S, Szostak JW Activated ribonucleotides undergo a sugar pucker switch upon binding to a single-stranded RNA template. J Am Chem Soc. 2012;134(8):3691-4 - PMID: 22296305 - PMCID: PMC3448298 - DOI: 10.1021/ja212027q

  • Szostak JW Attempts to define life do not help to understand the origin of life. J Biomol Struct Dyn. 2012;29(4):599-600 - PMID: 22208251 - PMCID: PMC4208307 - DOI: 10.1080/073911012010524998

  • Szostak JW An optimal degree of physical and chemical heterogeneity for the origin of life?. Philos Trans R Soc Lond B Biol Sci. 2011;366(1580):2894-901 - PMID: 21930580 - PMCID: PMC3158921 - DOI: 10.1098/rstb.2011.0140

  • Trevino SG, Zhang N, Elenko MP, Lupták A, Szostak JW Evolution of functional nucleic acids in the presence of nonheritable backbone heterogeneity. Proc Natl Acad Sci U S A. 2011;108(33):13492-7 - PMID: 21825162 - PMCID: PMC3158193 - DOI: 10.1073/pnas.1107113108

  • Seebeck FP, Ricardo A, Szostak JW Artificial lantipeptides from in vitro translations. Chem Commun (Camb). 2011;47(21):6141-3 - PMID: 21528125 - DOI: 10.1039/c0cc05663d

  • Budin I, Szostak JW Physical effects underlying the transition from primitive to modern cell membranes. Proc Natl Acad Sci U S A. 2011;108(13):5249-54 - PMID: 21402937 - PMCID: PMC3069173 - DOI: 10.1073/pnas.1100498108

  • Subtelny AO, Hartman MC, Szostak JW Optimal codon choice can improve the efficiency and fidelity of N-methyl amino acid incorporation into peptides by in-vitro translation. Angew Chem Int Ed Engl. 2011;50(14):3164-7 - PMID: 21381166 - PMCID: PMC4006073 - DOI: 10.1002/anie.201007686

  • Powner MW, Sutherland JD, Szostak JW Chemoselective multicomponent one-pot assembly of purine precursors in water. J Am Chem Soc. 2010;132(46):16677-88 - PMID: 21043502 - PMCID: PMC2984373 - DOI: 10.1021/ja108197s

  • Szostak JW DNA ends: just the beginning (Nobel lecture). Angew Chem Int Ed Engl. 2010;49(41):7386-404 - PMID: 20818632 - DOI: 10.1002/anie.201000635

  • Elenko MP, Szostak JW, van Oijen AM Single-molecule binding experiments on long time scales. Rev Sci Instrum. 2010;81(8):083705 - PMID: 20815611 - DOI: 10.1063/1.3473936

  • Budin I, Szostak JW Expanding roles for diverse physical phenomena during the origin of life. Annu Rev Biophys. 2010;39:245-63 - PMID: 20192779 - PMCID: PMC4992673 - DOI: 10.1146/annurev.biophys.050708.133753

  • Schrum JP, Zhu TF, Szostak JW The origins of cellular life. Cold Spring Harb Perspect Biol. 2010;2(9):a002212 - PMID: 20484387 - PMCID: PMC2926753 - DOI: 10.1101/cshperspect.a002212

  • Rajamani S, Ichida JK, Antal T, Treco DA, Leu K, Nowak MA, Szostak JW, Chen IA Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication. J Am Chem Soc. 2010;132(16):5880-5 - PMID: 20359213 - PMCID: PMC2857888 - DOI: 10.1021/ja100780p

  • Bruckner RJ, Mansy SS, Ricardo A, Mahadevan L, Szostak JW Flip-flop-induced relaxation of bending energy: implications for membrane remodeling. Biophys J. 2009;97(12):3113-22 - PMID: 20006948 - PMCID: PMC2793357 - DOI: 10.1016/j.bpj.2009.09.025

  • Schrum JP, Ricardo A, Krishnamurthy M, Blain JC, Szostak JW Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers. J Am Chem Soc. 2009;131(40):14560-70 - PMID: 19757789 - PMCID: PMC2759813 - DOI: 10.1021/ja906557v

  • Mansy SS, Szostak JW Reconstructing the emergence of cellular life through the synthesis of model protocells. Cold Spring Harb Symp Quant Biol. 2009;74:47-54 - PMID: 19734203 - DOI: 10.1101/sqb.2009.74.014

  • Ricardo A, Szostak JW Origin of life on earth. Sci Am. 2009;301(3):54-61 - PMID: 19708528 - DOI: 10.1038/scientificamerican0909-54

  • Lin S, Horning DP, Szostak JW, Chaput JC Conformational analysis of DNA repair intermediates by time-resolved fluorescence spectroscopy. J Phys Chem A. 2009;113(35):9585-7 - PMID: 19673467 - PMCID: PMC2733762 - DOI: 10.1021/jp906746w

  • Budin I, Bruckner RJ, Szostak JW Formation of protocell-like vesicles in a thermal diffusion column. J Am Chem Soc. 2009;131(28):9628-9 - PMID: 19601679 - PMCID: PMC2710859 - DOI: 10.1021/ja9029818

  • Elenko MP, Szostak JW, van Oijen AM Single-molecule imaging of an in vitro-evolved RNA aptamer reveals homogeneous ligand binding kinetics. J Am Chem Soc. 2009;131(29):9866-7 - PMID: 19572753 - PMCID: PMC2716146 - DOI: 10.1021/ja901880v

  • Szostak JW Origins of life: Systems chemistry on early Earth. Nature. 2009;459(7244):171-2 - PMID: 19444196 - DOI: 10.1038/459171a

  • Litovchick A, Szostak JW Retraction for Litovchick and Szostak. "Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display". Proc Natl Acad Sci U S A. 2009;106(17):7263 - PMID: 19380733 - PMCID: PMC2678432 - DOI: 10.1073/pnas.0903110106

  • Zhu TF, Szostak JW Preparation of large monodisperse vesicles. PLoS One. 2009;4(4):e5009 - PMID: 19347043 - PMCID: PMC2661144 - DOI: 10.1371/journal.pone.0005009

  • Zhu TF, Szostak JW Coupled growth and division of model protocell membranes. J Am Chem Soc. 2009;131(15):5705-13 - PMID: 19323552 - PMCID: PMC2669828 - DOI: 10.1021/ja900919c

  • Chen JJ, Tsai CH, Cai X, Horhota AT, McLaughlin LW, Szostak JW Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates. PLoS One. 2009;4(3):e4949 - PMID: 19305495 - PMCID: PMC2654545 - DOI: 10.1371/journal.pone.0004949

  • Chen JJ, Cai X, Szostak JW N2'-->p3' phosphoramidate glycerol nucleic acid as a potential alternative genetic system. J Am Chem Soc. 2009;131(6):2119-21 - PMID: 19166350 - PMCID: PMC2722806 - DOI: 10.1021/ja809069b

  • Litovchick A, Szostak JW Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display. Proc Natl Acad Sci U S A. 2008;105(40):15293-8 - PMID: 18824687 - PMCID: PMC2556359 - DOI: 10.1073/pnas.0805837105

  • Mansy SS, Szostak JW Thermostability of model protocell membranes. Proc Natl Acad Sci U S A. 2008;105(36):13351-5 - PMID: 18768808 - PMCID: PMC2528865 - DOI: 10.1073/pnas.0805086105

  • Mansy SS, Schrum JP, Krishnamurthy M, Tobé S, Treco DA, Szostak JW Template-directed synthesis of a genetic polymer in a model protocell. Nature. 2008;454(7200):122-5 - PMID: 18528332 - PMCID: PMC2743009 - DOI: 10.1038/nature07018

  • Subtelny AO, Hartman MC, Szostak JW Ribosomal synthesis of N-methyl peptides. J Am Chem Soc. 2008;130(19):6131-6 - PMID: 18402453 - PMCID: PMC2728122 - DOI: 10.1021/ja710016v

  • Monnard PA, Szostak JW Metal-ion catalyzed polymerization in the eutectic phase in water-ice: a possible approach to template-directed RNA polymerization. J Inorg Biochem. 2008;102(5-6):1104-11 - PMID: 18329104 - DOI: 10.1016/j.jinorgbio.2008.01.026

  • Hartman MC, Josephson K, Lin CW, Szostak JW An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides. PLoS One. 2007;2(10):e972 - PMID: 17912351 - PMCID: PMC1989143 - DOI: 10.1371/journal.pone.0000972

  • Tsai CH, Chen J, Szostak JW Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template. Proc Natl Acad Sci U S A. 2007;104(37):14598-603 - PMID: 17785419 - PMCID: PMC1976233 - DOI: 10.1073/pnas.0704211104

  • Seelig B, Szostak JW Selection and evolution of enzymes from a partially randomized non-catalytic scaffold. Nature. 2007;448(7155):828-31 - PMID: 17700701 - PMCID: PMC4476047 - DOI: 10.1038/nature06032

  • Mansy SS, Zhang J, Kümmerle R, Nilsson M, Chou JJ, Szostak JW, Chaput JC Structure and evolutionary analysis of a non-biological ATP-binding protein. J Mol Biol. 2007;371(2):501-13 - PMID: 17583732 - DOI: 10.1016/j.jmb.2007.05.062

  • Smith MD, Rosenow MA, Wang M, Allen JP, Szostak JW, Chaput JC Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization. PLoS One. 2007;2(5):e467 - PMID: 17520026 - PMCID: PMC1867856 - DOI: 10.1371/journal.pone.0000467

  • Hazen RM, Griffin PL, Carothers JM, Szostak JW Functional information and the emergence of biocomplexity. Proc Natl Acad Sci U S A. 2007;104 Suppl 1:8574-81 - PMID: 17494745 - PMCID: PMC1876432 - DOI: 10.1073/pnas.0701744104

  • Meena , Sam M, Pierce K, Szostak JW, McLaughlin LW 2',3'-Dideoxy-3'-thionucleoside triphosphates: syntheses and polymerase substrate activities. Org Lett. 2007;9(6):1161-3 - PMID: 17319676 - DOI: 10.1021/ol070147w

  • Horhota AT, Szostak JW, McLaughlin LW Glycerol nucleoside triphosphates: synthesis and polymerase substrate activities. Org Lett. 2006;8(23):5345-7 - PMID: 17078714 - DOI: 10.1021/ol062232u

  • Blackburn EH, Greider CW, Szostak JW Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging. Nat Med. 2006;12(10):1133-8 - PMID: 17024208 - DOI: 10.1038/nm1006-1133

  • Salehi-Ashtiani K, Lupták A, Litovchick A, Szostak JW A genomewide search for ribozymes reveals an HDV-like sequence in the human CPEB3 gene. Science. 2006;313(5794):1788-92 - PMID: 16990549 - DOI: 10.1126/science.1129308

  • Carothers JM, Oestreich SC, Szostak JW Aptamers selected for higher-affinity binding are not more specific for the target ligand. J Am Chem Soc. 2006;128(24):7929-37 - PMID: 16771507 - PMCID: PMC4287982 - DOI: 10.1021/ja060952q

  • Seebeck FP, Szostak JW Ribosomal synthesis of dehydroalanine-containing peptides. J Am Chem Soc. 2006;128(22):7150-1 - PMID: 16734454 - PMCID: PMC2572134 - DOI: 10.1021/ja060966w

  • Hartman MC, Josephson K, Szostak JW Enzymatic aminoacylation of tRNA with unnatural amino acids. Proc Natl Acad Sci U S A. 2006;103(12):4356-61 - PMID: 16537388 - PMCID: PMC1450175 - DOI: 10.1073/pnas.0509219103

  • Carothers JM, Davis JH, Chou JJ, Szostak JW Solution structure of an informationally complex high-affinity RNA aptamer to GTP. RNA. 2006;12(4):567-79 - PMID: 16510427 - PMCID: PMC1421093 - DOI: 10.1261/rna.2251306

  • Cho GS, Szostak JW Directed evolution of ATP binding proteins from a zinc finger domain by using mRNA display. Chem Biol. 2006;13(2):139-47 - PMID: 16492562 - DOI: 10.1016/j.chembiol.2005.10.015

  • Fujikawa SM, Chen IA, Szostak JW Shrink-wrap vesicles. Langmuir. 2005;21(26):12124-9 - PMID: 16342983 - PMCID: PMC2548281 - DOI: 10.1021/la052590q

  • Plummer KA, Carothers JM, Yoshimura M, Szostak JW, Verdine GL In vitro selection of RNA aptamers against a composite small molecule-protein surface. Nucleic Acids Res. 2005;33(17):5602-10 - PMID: 16199752 - PMCID: PMC1240114 - DOI: 10.1093/nar/gki867

  • Ichida JK, Horhota A, Zou K, McLaughlin LW, Szostak JW High fidelity TNA synthesis by Therminator polymerase. Nucleic Acids Res. 2005;33(16):5219-25 - PMID: 16157867 - PMCID: PMC1214552 - DOI: 10.1093/nar/gki840

  • Chen IA, Salehi-Ashtiani K, Szostak JW RNA catalysis in model protocell vesicles. J Am Chem Soc. 2005;127(38):13213-9 - PMID: 16173749 - PMCID: PMC5072289 - DOI: 10.1021/ja051784p

  • Josephson K, Hartman MC, Szostak JW Ribosomal synthesis of unnatural peptides. J Am Chem Soc. 2005;127(33):11727-35 - PMID: 16104750 - DOI: 10.1021/ja0515809

  • Horhota A, Zou K, Ichida JK, Yu B, McLaughlin LW, Szostak JW, Chaput JC Kinetic analysis of an efficient DNA-dependent TNA polymerase. J Am Chem Soc. 2005;127(20):7427-34 - PMID: 15898792 - PMCID: PMC5042361 - DOI: 10.1021/ja0428255

  • Shen X, Valencia CA, Szostak JW, Szostak J, Dong B, Liu R Scanning the human proteome for calmodulin-binding proteins. Proc Natl Acad Sci U S A. 2005;102(17):5969-74 - PMID: 15840729 - PMCID: PMC1087907 - DOI: 10.1073/pnas.0407928102

  • Sacerdote MG, Szostak JW Semipermeable lipid bilayers exhibit diastereoselectivity favoring ribose. Proc Natl Acad Sci U S A. 2005;102(17):6004-8 - PMID: 15831588 - PMCID: PMC556129 - DOI: 10.1073/pnas.0408440102

  • Zou K, Horhota A, Yu B, Szostak JW, McLaughlin LW Synthesis of alpha-L-threofuranosyl nucleoside triphosphates (tNTPs). Org Lett. 2005;7(8):1485-7 - PMID: 15816733 - PMCID: PMC5022784 - DOI: 10.1021/ol050081+

  • Ichida JK, Zou K, Horhota A, Yu B, McLaughlin LW, Szostak JW An in vitro selection system for TNA. J Am Chem Soc. 2005;127(9):2802-3 - PMID: 15740086 - PMCID: PMC5072288 - DOI: 10.1021/ja045364w

  • Hanczyc MM, Szostak JW Replicating vesicles as models of primitive cell growth and division. Curr Opin Chem Biol. 2004;8(6):660-4 - PMID: 15556412 - DOI: 10.1016/j.cbpa.2004.10.002

  • Chen IA, Roberts RW, Szostak JW The emergence of competition between model protocells. Science. 2004;305(5689):1474-6 - PMID: 15353806 - PMCID: PMC4484590 - DOI: 10.1126/science.1100757

  • Chen IA, Szostak JW A kinetic study of the growth of fatty acid vesicles. Biophys J. 2004;87(2):988-98 - PMID: 15298905 - PMCID: PMC1304506 - DOI: 10.1529/biophysj.104.039875

  • Sazani PL, Larralde R, Szostak JW A small aptamer with strong and specific recognition of the triphosphate of ATP. J Am Chem Soc. 2004;126(27):8370-1 - PMID: 15237981 - PMCID: PMC4983724 - DOI: 10.1021/ja049171k

  • Chaput JC, Szostak JW Evolutionary optimization of a nonbiological ATP binding protein for improved folding stability. Chem Biol. 2004;11(6):865-74 - PMID: 15217619 - DOI: 10.1016/j.chembiol.2004.04.006

  • Chen IA, Szostak JW Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles. Proc Natl Acad Sci U S A. 2004;101(21):7965-70 - PMID: 15148394 - PMCID: PMC419540 - DOI: 10.1073/pnas.0308045101

  • Carothers JM, Oestreich SC, Davis JH, Szostak JW Informational complexity and functional activity of RNA structures. J Am Chem Soc. 2004;126(16):5130-7 - PMID: 15099096 - PMCID: PMC5042360 - DOI: 10.1021/ja031504a

  • Huang Z, Szostak JW Evolution of aptamers with a new specificity and new secondary structures from an ATP aptamer. RNA. 2003;9(12):1456-63 - PMID: 14624002 - PMCID: PMC1370500 - DOI: 10.1261/rna.5990203

  • Hanczyc MM, Fujikawa SM, Szostak JW Experimental models of primitive cellular compartments: encapsulation, growth, and division. Science. 2003;302(5645):618-22 - PMID: 14576428 - PMCID: PMC4484575 - DOI: 10.1126/science.1089904

  • Chaput JC, Szostak JW TNA synthesis by DNA polymerases. J Am Chem Soc. 2003;125(31):9274-5 - PMID: 12889939 - DOI: 10.1021/ja035917n

  • Vaish NK, Larralde R, Fraley AW, Szostak JW, McLaughlin LW A novel, modification-dependent ATP-binding aptamer selected from an RNA library incorporating a cationic functionality. Biochemistry. 2003;42(29):8842-51 - PMID: 12873145 - DOI: 10.1021/bi027354i

  • Szostak JW Functional information: Molecular messages. Nature. 2003;423(6941):689 - PMID: 12802312 - DOI: 10.1038/423689a

  • Huang Z, Szostak JW Selective labeling and detection of specific RNAs in an RNA mixture. Anal Biochem. 2003;315(1):129-33 - PMID: 12672421 - DOI: 10.1016/s0003-2697(02)00701-7

  • Chaput JC, Ichida JK, Szostak JW DNA polymerase-mediated DNA synthesis on a TNA template. J Am Chem Soc. 2003;125(4):856-7 - PMID: 12537469 - DOI: 10.1021/ja028589k

  • Szostak JW Molecular biology: RNA gets a grip on translation. Nature. 2002;419(6910):890-1 - PMID: 12410294 - DOI: 10.1038/419890a

  • Baggio R, Burgstaller P, Hale SP, Putney AR, Lane M, Lipovsek D, Wright MC, Roberts RW, Liu R, Szostak JW, Wagner RW Identification of epitope-like consensus motifs using mRNA display. J Mol Recognit. 2002;15(3):126-34 - PMID: 12203838 - DOI: 10.1002/jmr.567

  • Davis JH, Szostak JW Isolation of high-affinity GTP aptamers from partially structured RNA libraries. Proc Natl Acad Sci U S A. 2002;99(18):11616-21 - PMID: 12185247 - PMCID: PMC129318 - DOI: 10.1073/pnas.182095699

  • Keefe AD, Wilson DS, Seelig B, Szostak JW One-step purification of recombinant proteins using a nanomolar-affinity streptavidin-binding peptide, the SBP-Tag. Protein Expr Purif. 2001;23(3):440-6 - PMID: 11722181 - DOI: 10.1006/prep.2001.1515

  • Salehi-Ashtiani K, Szostak JW In vitro evolution suggests multiple origins for the hammerhead ribozyme. Nature. 2001;414(6859):82-4 - PMID: 11689947 - DOI: 10.1038/35102081

  • Keefe AD, Szostak JW Functional proteins from a random-sequence library. Nature. 2001;410(6829):715-8 - PMID: 11287961 - PMCID: PMC4476321 - DOI: 10.1038/35070613

  • Wilson DS, Keefe AD, Szostak JW The use of mRNA display to select high-affinity protein-binding peptides. Proc Natl Acad Sci U S A. 2001;98(7):3750-5 - PMID: 11274392 - PMCID: PMC31124 - DOI: 10.1073/pnas.061028198

  • Szostak JW, Bartel DP, Luisi PL Synthesizing life. Nature. 2001;409(6818):387-90 - PMID: 11201752 - DOI: 10.1038/35053176

  • Liu R, Barrick JE, Szostak JW, Roberts RW Optimized synthesis of RNA-protein fusions for in vitro protein selection. Methods Enzymol. 2000;318:268-93 - PMID: 10889994 - DOI: 10.1016/s0076-6879(00)18058-9

  • Szostak JW In vitro selection and directed evolution. Harvey Lect. 2000;93:95-118 - PMID: 10941421

  • Vaish NK, Fraley AW, Szostak JW, McLaughlin LW Expanding the structural and functional diversity of RNA: analog uridine triphosphates as candidates for in vitro selection of nucleic acids. Nucleic Acids Res. 2000;28(17):3316-22 - PMID: 10954600 - PMCID: PMC110695 - DOI: 10.1093/nar/28.17.3316

  • Wilson DS, Szostak JW In vitro selection of functional nucleic acids. Annu Rev Biochem. 2000;68:611-47 - PMID: 10872462 - DOI: 10.1146/annurev.biochem.68.1.611

  • Cho G, Keefe AD, Liu R, Wilson DS, Szostak JW Constructing high complexity synthetic libraries of long ORFs using in vitro selection. J Mol Biol. 2000;297(2):309-19 - PMID: 10715203 - DOI: 10.1006/jmbi.2000.3571

  • Lee N, Bessho Y, Wei K, Szostak JW, Suga H Ribozyme-catalyzed tRNA aminoacylation. Nat Struct Biol. 2000;7(1):28-33 - PMID: 10625423 - DOI: 10.1038/71225

  • Holeman LA, Robinson SL, Szostak JW, Wilson C Isolation and characterization of fluorophore-binding RNA aptamers. Fold Des. 1999;3(6):423-31 - PMID: 9889155 - DOI: 10.1016/S1359-0278(98)00059-5

  • Wilson C, Szostak JW Isolation of a fluorophore-specific DNA aptamer with weak redox activity. Chem Biol. 1998;5(11):609-17 - PMID: 9831529 - DOI: 10.1016/s1074-5521(98)90289-7

  • Suga H, Cowan JA, Szostak JW Unusual metal ion catalysis in an acyl-transferase ribozyme. Biochemistry. 1998;37(28):10118-25 - PMID: 9665717 - DOI: 10.1021/bi980432a

  • Suga H, Lohse PA, Szostak JW Structural and kinetic characterization of an acyl transferase ribozyme. J Am Chem Soc. 1998;120(6):1151-6 - PMID: 11541113 - DOI: 10.1021/ja972472s

  • Roberts RW, Szostak JW RNA-peptide fusions for the in vitro selection of peptides and proteins. Proc Natl Acad Sci U S A. 1997;94(23):12297-302 - PMID: 9356443 - PMCID: PMC24913 - DOI: 10.1073/pnas.94.23.12297

  • Dieckmann T, Butcher SE, Sassanfar M, Szostak JW, Feigon J Mutant ATP-binding RNA aptamers reveal the structural basis for ligand binding. J Mol Biol. 1997;273(2):467-78 - PMID: 9344753 - DOI: 10.1006/jmbi.1997.1329

  • Chapman KB, Szostak JW In vitro selection of catalytic RNAs. Curr Opin Struct Biol. 1997;4:618-22 - PMID: 11539575 - DOI: 10.1016/s0959-440x(94)90227-5

  • Hager AJ, Szostak JW Isolation of novel ribozymes that ligate AMP-activated RNA substrates. Chem Biol. 1997;4(8):607-17 - PMID: 9281527 - DOI: 10.1016/s1074-5521(97)90246-5

  • Szostak JW Introduction: Combinatorial Chemistry. Chem Rev. 1997;97(2):347-348 - PMID: 11848873 - DOI: 10.1021/cr9700080

  • Huang Z, Szostak JW A simple method for 3'-labeling of RNA. Nucleic Acids Res. 1996;24(21):4360-1 - PMID: 8932396 - PMCID: PMC146232 - DOI: 10.1093/nar/24.21.4360

  • Hager AJ, Pollard JD, Szostak JW Ribozymes: aiming at RNA replication and protein synthesis. Chem Biol. 1996;3(9):717-25 - PMID: 8939686 - DOI: 10.1016/s1074-5521(96)90246-x

  • Lohse PA, Szostak JW Ribozyme-catalysed amino-acid transfer reactions. Nature. 1996;381(6581):442-4 - PMID: 8632803 - DOI: 10.1038/381442a0

  • Rohatgi R, Bartel DP, Szostak JW Nonenzymatic, template-directed ligation of oligoribonucleotides is highly regioselective for the formation of 3'-5' phosphodiester bonds. J Am Chem Soc. 1996;118(14):3340-4 - PMID: 11539268 - DOI: 10.1021/ja9537134

  • Rohatgi R, Bartel DP, Szostak JW Kinetic and mechanistic analysis of nonenzymatic, template-directed oligoribonucleotide ligation. J Am Chem Soc. 1996;118(14):3332-9 - PMID: 11539267 - DOI: 10.1021/ja953712b

  • Lorsch JR, Szostak JW Chance and necessity in the selection of nucleic acid catalysts. Acc Chem Res. 1996;29(2):103-10 - PMID: 11539421 - DOI: 10.1021/ar9501378

  • Lorsch JR, Szostak JW Kinetic and thermodynamic characterization of the reaction catalyzed by a polynucleotide kinase ribozyme. Biochemistry. 1995;34(46):15315-27 - PMID: 7578148 - DOI: 10.1021/bi00046a041

  • Lorsch JR, Bartel DP, Szostak JW Reverse transcriptase reads through a 2'-5'linkage and a 2'-thiophosphate in a template. Nucleic Acids Res. 1995;23(15):2811-4 - PMID: 7544885 - PMCID: PMC307115 - DOI: 10.1093/nar/23.15.2811

  • Ekland EH, Szostak JW, Bartel DP Structurally complex and highly active RNA ligases derived from random RNA sequences. Science. 1995;269(5222):364-70 - PMID: 7618102 - DOI: 10.1126/science.7618102

  • Cuenoud B, Szostak JW A DNA metalloenzyme with DNA ligase activity. Nature. 1995;375(6532):611-4 - PMID: 7791880 - DOI: 10.1038/375611a0

  • Chapman KB, Szostak JW Isolation of a ribozyme with 5'-5' ligase activity. Chem Biol. 1995;2(5):325-33 - PMID: 9383434 - DOI: 10.1016/1074-5521(95)90051-9

  • Wilson C, Szostak JW In vitro evolution of a self-alkylating ribozyme. Nature. 1995;374(6525):777-82 - PMID: 7723823 - DOI: 10.1038/374777a0

  • Whoriskey SK, Usman N, Szostak JW Total chemical synthesis of a ribozyme derived from a group I intron. Proc Natl Acad Sci U S A. 1995;92(7):2465-9 - PMID: 7708666 - PMCID: PMC42238 - DOI: 10.1073/pnas.92.7.2465

  • Lauhon CT, Szostak JW RNA aptamers that bind flavin and nicotinamide redox cofactors. J Am Chem Soc. 1995;117(4):1246-57 - PMID: 11539282 - DOI: 10.1021/ja00109a008

  • Huizenga DE, Szostak JW A DNA aptamer that binds adenosine and ATP. Biochemistry. 1995;34(2):656-65 - PMID: 7819261 - DOI: 10.1021/bi00002a033

  • Hanna M, Szostak JW Suppression of mutations in the core of the Tetrahymena ribozyme by spermidine, ethanol and by substrate stabilization. Nucleic Acids Res. 1994;22(24):5326-31 - PMID: 7816622 - PMCID: PMC332078 - DOI: 10.1093/nar/22.24.5326

  • Lorsch JR, Szostak JW In vitro evolution of new ribozymes with polynucleotide kinase activity. Nature. 1994;371(6492):31-6 - PMID: 7521014 - DOI: 10.1038/371031a0

  • Peterson RD, Bartel DP, Szostak JW, Horvath SJ, Feigon J 1H NMR studies of the high-affinity Rev binding site of the Rev responsive element of HIV-1 mRNA: base pairing in the core binding element. Biochemistry. 1994;33(18):5357-66 - PMID: 8180157 - DOI: 10.1021/bi00184a001

  • Lin CW, Hanna M, Szostak JW Evidence that the guanosine substrate of the Tetrahymena ribozyme is bound in the anti conformation and that N7 contributes to binding. Biochemistry. 1994;33(9):2703-7 - PMID: 8117735 - DOI: 10.1021/bi00175a045

  • Lorsch JR, Szostak JW In vitro selection of RNA aptamers specific for cyanocobalamin. Biochemistry. 1994;33(4):973-82 - PMID: 7508262 - DOI: 10.1021/bi00170a016

  • Green R, Szostak JW In vitro genetic analysis of the hinge region between helical elements P5-P4-P6 and P7-P3-P8 in the sunY group I self-splicing intron. J Mol Biol. 1994;235(1):140-55 - PMID: 7507168 - DOI: 10.1016/s0022-2836(05)80022-1

  • Bartel DP, Szostak JW Isolation of new ribozymes from a large pool of random sequences [see comment]. Science. 1993;261(5127):1411-8 - PMID: 7690155 - DOI: 10.1126/science.7690155

  • Sassanfar M, Szostak JW An RNA motif that binds ATP. Nature. 1993;364(6437):550-3 - PMID: 7687750 - DOI: 10.1038/364550a0

  • Doudna JA, Usman N, Szostak JW Ribozyme-catalyzed primer extension by trinucleotides: a model for the RNA-catalyzed replication of RNA. Biochemistry. 1993;32(8):2111-5 - PMID: 7680575 - DOI: 10.1021/bi00059a032

  • Szostak JW Ribozymes. Evolution ex vivo. Nature. 1993;361(6408):119-20 - PMID: 7678448 - DOI: 10.1038/361119a0

  • Green R, Szostak JW Selection of a ribozyme that functions as a superior template in a self-copying reaction. Science. 1992;258(5090):1910-5 - PMID: 1470913 - DOI: 10.1126/science.1470913

  • Ross LO, Treco D, Nicolas A, Szostak JW, Dawson D Meiotic recombination on artificial chromosomes in yeast. Genetics. 1992;131(3):541-50 - PMID: 1385793 - PMCID: PMC1205028

  • Park EC, Szostak JW ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity. EMBO J. 1992;11(6):2087-93 - PMID: 1600941 - PMCID: PMC556675

  • Szostak JW In vitro genetics. Trends Biochem Sci. 1992;17(3):89-93 - PMID: 1384177 - DOI: 10.1016/0968-0004(92)90242-2

  • Ellington AD, Szostak JW Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures. Nature. 1992;355(6363):850-2 - PMID: 1538766 - DOI: 10.1038/355850a0

  • Park EC, Finley D, Szostak JW A strategy for the generation of conditional mutations by protein destabilization. Proc Natl Acad Sci U S A. 1992;89(4):1249-52 - PMID: 1311090 - PMCID: PMC48426 - DOI: 10.1073/pnas.89.4.1249

  • Sun H, Dawson D, Szostak JW Genetic and physical analyses of sister chromatid exchange in yeast meiosis. Mol Cell Biol. 1991;11(12):6328-36 - PMID: 1944292 - PMCID: PMC361828 - DOI: 10.1128/mcb.11.12.6328

  • Bartel DP, Zapp ML, Green MR, Szostak JW HIV-1 Rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA. Cell. 1991;67(3):529-36 - PMID: 1934059 - DOI: 10.1016/0092-8674(91)90527-6

  • Green R, Szostak JW, Benner SA, Rich A, Usman N Synthesis of RNA containing inosine: analysis of the sequence requirements for the 5' splice site of the Tetrahymena group I intron. Nucleic Acids Res. 1991;19(15):4161-6 - PMID: 1714564 - PMCID: PMC328556 - DOI: 10.1093/nar/19.15.4161

  • Bartel DP, Doudna JA, Usman N, Szostak JW Template-directed primer extension catalyzed by the Tetrahymena ribozyme. Mol Cell Biol. 1991;11(6):3390-4 - PMID: 2038341 - PMCID: PMC360195 - DOI: 10.1128/mcb.11.6.3390

  • Sun H, Treco D, Szostak JW Extensive 3'-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation site. Cell. 1991;64(6):1155-61 - PMID: 2004421 - DOI: 10.1016/0092-8674(91)90270-9

  • Pace U, Szostak JW Mutations in a semiconserved region of the Tetrahymena intron. FEBS Lett. 1991;280(1):171-4 - PMID: 2009960 - DOI: 10.1016/0014-5793(91)80230-z

  • Doudna JA, Couture S, Szostak JW A multisubunit ribozyme that is a catalyst of and template for complementary strand RNA synthesis. Science. 1991;251(5001):1605-8 - PMID: 1707185 - DOI: 10.1126/science.1707185

  • Schultes NP, Szostak JW A poly(dA.dT) tract is a component of the recombination initiation site at the ARG4 locus in Saccharomyces cerevisiae. Mol Cell Biol. 1991;11(1):322-8 - PMID: 1986228 - PMCID: PMC359622 - DOI: 10.1128/mcb.11.1.322

  • Schultes NP, Ellington AD, Cherry JM, Szostak JW Saccharomyces cerevisiae homoserine kinase is homologous to prokaryotic homoserine kinases. Gene. 1990;96(2):177-80 - PMID: 2176637 - DOI: 10.1016/0378-1119(90)90250-u

  • Schultes NP, Szostak JW Decreasing gradients of gene conversion on both sides of the initiation site for meiotic recombination at the ARG4 locus in yeast. Genetics. 1990;126(4):813-22 - PMID: 1981763 - PMCID: PMC1204280

  • Doudna JA, Szostak JW, Rich A, Usman N Chemical synthesis of oligoribonucleotides containing 2-aminopurine: substrates for the investigation of ribozyme function. J Org Chem. 1990;55(21):5547-9 - PMID: 11540922 - DOI: 10.1021/jo00308a003

  • Couture S, Ellington AD, Gerber AS, Cherry JM, Doudna JA, Green R, Hanna M, Pace U, Rajagopal J, Szostak JW Mutational analysis of conserved nucleotides in a self-splicing group I intron. J Mol Biol. 1990;215(3):345-58 - PMID: 1700131 - DOI: 10.1016/s0022-2836(05)80356-0

  • Michel F, Ellington AD, Couture S, Szostak JW Phylogenetic and genetic evidence for base-triples in the catalytic domain of group I introns. Nature. 1990;347(6293):578-80 - PMID: 2215683 - DOI: 10.1038/347578a0

  • Lichten M, Goyon C, Schultes NP, Treco D, Szostak JW, Haber JE, Nicolas A Detection of heteroduplex DNA molecules among the products of Saccharomyces cerevisiae meiosis. Proc Natl Acad Sci U S A. 1990;87(19):7653-7 - PMID: 2217196 - PMCID: PMC54806 - DOI: 10.1073/pnas.87.19.7653

  • Park EC, Szostak JW Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML. Mol Cell Biol. 1990;10(9):4932-4 - PMID: 2117703 - PMCID: PMC361112 - DOI: 10.1128/mcb.10.9.4932

  • Green R, Ellington AD, Szostak JW In vitro genetic analysis of the Tetrahymena self-splicing intron. Nature. 1990;347(6291):406-8 - PMID: 2215650 - DOI: 10.1038/347406a0

  • Ellington AD, Szostak JW In vitro selection of RNA molecules that bind specific ligands. Nature. 1990;346(6287):818-22 - PMID: 1697402 - DOI: 10.1038/346818a0

  • Doudna JA, Szostak JW Miniribozymes, small derivatives of the sunY intron, are catalytically active. Mol Cell Biol. 1989;9(12):5480-3 - PMID: 2685567 - PMCID: PMC363717 - DOI: 10.1128/mcb.9.12.5480

  • Michel F, Hanna M, Green R, Bartel DP, Szostak JW The guanosine binding site of the Tetrahymena ribozyme. Nature. 1989;342(6248):391-5 - PMID: 2685606 - DOI: 10.1038/342391a0

  • Doudna JA, Cormack BP, Szostak JW RNA structure, not sequence, determines the 5' splice-site specificity of a group I intron. Proc Natl Acad Sci U S A. 1989;86(19):7402-6 - PMID: 2678103 - PMCID: PMC298070 - DOI: 10.1073/pnas.86.19.7402

  • Doudna JA, Szostak JW RNA-catalysed synthesis of complementary-strand RNA. Nature. 1989;339(6225):519-22 - PMID: 2660003 - DOI: 10.1038/339519a0

  • Lundblad V, Szostak JW A mutant with a defect in telomere elongation leads to senescence in yeast. Cell. 1989;57(4):633-43 - PMID: 2655926 - DOI: 10.1016/0092-8674(89)90132-3

  • Rajagopal J, Doudna JA, Szostak JW Stereochemical course of catalysis by the Tetrahymena ribozyme. Science. 1989;244(4905):692-4 - PMID: 2470151 - DOI: 10.1126/science.2470151

  • Nicolas A, Treco D, Schultes NP, Szostak JW An initiation site for meiotic gene conversion in the yeast Saccharomyces cerevisiae. Nature. 1989;338(6210):35-9 - PMID: 2537472 - DOI: 10.1038/338035a0

  • Sun H, Treco D, Schultes NP, Szostak JW Double-strand breaks at an initiation site for meiotic gene conversion. Nature. 1989;338(6210):87-90 - PMID: 2645528 - DOI: 10.1038/338087a0

  • Szostak JW Telomerase: the beginning of the ends. Nature. 1989;337(6205):303-4 - PMID: 2765013 - DOI: 10.1038/337303a0

  • Orr-Weaver TL, Nicolas A, Szostak JW Gene conversion adjacent to regions of double-strand break repair. Mol Cell Biol. 1988;8(12):5292-8 - PMID: 3072478 - PMCID: PMC365631 - DOI: 10.1128/mcb.8.12.5292

  • Murray AW, Claus TE, Szostak JW Characterization of two telomeric DNA processing reactions in Saccharomyces cerevisiae. Mol Cell Biol. 1988;8(11):4642-50 - PMID: 3062364 - PMCID: PMC365553 - DOI: 10.1128/mcb.8.11.4642

  • Doudna JA, Gerber AS, Cherry JM, Szostak JW Genetic dissection of an RNA enzyme. Cold Spring Harb Symp Quant Biol. 1988;52:173-80 - PMID: 2456876 - DOI: 10.1101/sqb.1987.052.01.022

  • Allshire RC, Gosden JR, Cross SH, Cranston G, Rout D, Sugawara N, Szostak JW, Fantes PA, Hastie ND Telomeric repeat from T. thermophila cross hybridizes with human telomeres. Nature. 1988;332(6165):656-9 - PMID: 2833706 - DOI: 10.1038/332656a0

  • Matsumoto T, Fukui K, Niwa O, Sugawara N, Szostak JW, Yanagida M Identification of healed terminal DNA fragments in linear minichromosomes of Schizosaccharomyces pombe. Mol Cell Biol. 1987;7(12):4424-30 - PMID: 2830493 - PMCID: PMC368126 - DOI: 10.1128/mcb.7.12.4424

  • Murray AW, Szostak JW Artificial chromosomes. Sci Am. 1987;257(5):62-8 - PMID: 3317814 - DOI: 10.1038/scientificamerican1187-62

  • Reynolds AE, Murray AW, Szostak JW Roles of the 2 microns gene products in stable maintenance of the 2 microns plasmid of Saccharomyces cerevisiae. Mol Cell Biol. 1987;7(10):3566-73 - PMID: 3316982 - PMCID: PMC368010 - DOI: 10.1128/mcb.7.10.3566

  • Whiteway M, Freedman R, Van Arsdell S, Szostak JW, Thorner J The yeast ARD1 gene product is required for repression of cryptic mating-type information at the HML locus. Mol Cell Biol. 1987;7(10):3713-22 - PMID: 3316986 - PMCID: PMC368027 - DOI: 10.1128/mcb.7.10.3713

  • Burke JM, Belfort M, Cech TR, Davies RW, Schweyen RJ, Shub DA, Szostak JW, Tabak HF Structural conventions for group I introns. Nucleic Acids Res. 1987;15(18):7217-21 - PMID: 3658691 - PMCID: PMC306243 - DOI: 10.1093/nar/15.18.7217

  • Murray AW, Szostak JW Chromosome segregation in mitosis and meiosis. Annu Rev Cell Biol. 1987;1:289-315 - PMID: 3916318 - DOI: 10.1146/annurev.cb.01.110185.001445

  • Dawson DS, Murray AW, Szostak JW An alternative pathway for meiotic chromosome segregation in yeast. Science. 1986;234(4777):713-7 - PMID: 3535068 - DOI: 10.1126/science.3535068

  • Murray AW, Szostak JW Construction and behavior of circularly permuted and telocentric chromosomes in Saccharomyces cerevisiae. Mol Cell Biol. 1986;6(9):3166-72 - PMID: 3537731 - PMCID: PMC367052 - DOI: 10.1128/mcb.6.9.3166

  • Szostak JW Enzymatic activity of the conserved core of a group I self-splicing intron. Nature. 1986;322(6074):83-6 - PMID: 3014350 - DOI: 10.1038/322083a0

  • Murray AW, Schultes NP, Szostak JW Chromosome length controls mitotic chromosome segregation in yeast. Cell. 1986;45(4):529-36 - PMID: 3518944 - DOI: 10.1016/0092-8674(86)90284-9

  • Whiteway M, Szostak JW The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways. Cell. 1985;43(2 Pt 1):483-92 - PMID: 3907857 - DOI: 10.1016/0092-8674(85)90178-3

  • Orr-Weaver TL, Szostak JW Fungal recombination. Microbiol Rev. 1985;49(1):33-58 - PMID: 3884994 - PMCID: PMC373016 - DOI: 10.1128/mr.49.1.33-58.1985

  • Ruby SW, Szostak JW Specific Saccharomyces cerevisiae genes are expressed in response to DNA-damaging agents. Mol Cell Biol. 1985;5(1):75-84 - PMID: 3920512 - PMCID: PMC366680 - DOI: 10.1128/mcb.5.1.75

  • Dunn B, Szauter P, Pardue ML, Szostak JW Transfer of yeast telomeres to linear plasmids by recombination. Cell. 1984;39(1):191-201 - PMID: 6091911 - DOI: 10.1016/0092-8674(84)90205-8

  • Shampay J, Szostak JW, Blackburn EH DNA sequences of telomeres maintained in yeast. Nature. 1984;310(5973):154-7 - PMID: 6330571 - DOI: 10.1038/310154a0

  • Sugawara N, Szostak JW Construction of specific chromosomal rearrangements in yeast. Methods Enzymol. 1983;101:269-78 - PMID: 6310329 - DOI: 10.1016/0076-6879(83)01020-4

  • Murray AW, Szostak JW Construction of artificial chromosomes in yeast. Nature. 1983;305(5931):189-93 - PMID: 6350893 - DOI: 10.1038/305189a0

  • Brown PA, Szostak JW Yeast vectors with negative selection. Methods Enzymol. 1983;101:278-90 - PMID: 6310330 - DOI: 10.1016/0076-6879(83)01021-6

  • Ruby SW, Szostak JW, Murray AW Cloning regulated yeast genes from a pool of lacZ fusions. Methods Enzymol. 1983;101:253-69 - PMID: 6310328 - DOI: 10.1016/0076-6879(83)01019-8

  • Orr-Weaver TL, Szostak JW, Rothstein RJ Genetic applications of yeast transformation with linear and gapped plasmids. Methods Enzymol. 1983;101:228-45 - PMID: 6310326 - DOI: 10.1016/0076-6879(83)01017-4

  • Szostak JW A rapid procedure for the construction of linear yeast plasmids. Methods Enzymol. 1983;101:245-52 - PMID: 6310327 - DOI: 10.1016/0076-6879(83)01018-6

  • Murray AW, Szostak JW Pedigree analysis of plasmid segregation in yeast. Cell. 1983;34(3):961-70 - PMID: 6354471 - DOI: 10.1016/0092-8674(83)90553-6

  • Sugawara N, Szostak JW Recombination between sequences in nonhomologous positions. Proc Natl Acad Sci U S A. 1983;80(18):5675-9 - PMID: 6351064 - PMCID: PMC384321 - DOI: 10.1073/pnas.80.18.5675

  • Szostak JW Replication and resolution of telomeres in yeast. Cold Spring Harb Symp Quant Biol. 1983;47 Pt 2:1187-94 - PMID: 6305577 - DOI: 10.1101/sqb.1983.047.01.134

  • Orr-Weaver TL, Szostak JW Yeast recombination: the association between double-strand gap repair and crossing-over. Proc Natl Acad Sci U S A. 1983;80(14):4417-21 - PMID: 6308623 - PMCID: PMC384049 - DOI: 10.1073/pnas.80.14.4417

  • Szostak JW, Orr-Weaver TL, Rothstein RJ, Stahl FW The double-strand-break repair model for recombination. Cell. 1983;33(1):25-35 - PMID: 6380756 - DOI: 10.1016/0092-8674(83)90331-8

  • Orr-Weaver TL, Szostak JW Multiple, tandem plasmid integration in Saccharomyces cerevisiae. Mol Cell Biol. 1983;3(4):747-9 - PMID: 6343844 - PMCID: PMC368590 - DOI: 10.1128/mcb.3.4.747

  • Walmsley RM, Szostak JW, Petes TD Is there left-handed DNA at the ends of yeast chromosomes?. Nature. 1983;302(5903):84-6 - PMID: 6338397 - DOI: 10.1038/302084a0

  • Szostak JW, Blackburn EH Cloning yeast telomeres on linear plasmid vectors. Cell. 1982;29(1):245-55 - PMID: 6286143 - DOI: 10.1016/0092-8674(82)90109-x

  • Orr-Weaver TL, Szostak JW, Rothstein RJ Yeast transformation: a model system for the study of recombination. Proc Natl Acad Sci U S A. 1981;78(10):6354-8 - PMID: 6273866 - PMCID: PMC349037 - DOI: 10.1073/pnas.78.10.6354

  • Stiles JI, Szostak JW, Young AT, Wu R, Consaul S, Sherman F DNA sequence of a mutation in the leader region of the yeast iso-1-cytochrome c mRNA. Cell. 1981;25(1):277-84 - PMID: 6268305 - DOI: 10.1016/0092-8674(81)90253-1

  • Szostak JW, Stiles JI, Tye BK, Chiu P, Sherman F, Wu R Hybridization with synthetic oligonucleotides. Methods Enzymol. 1980;68:419-28 - PMID: 161605 - DOI: 10.1016/0076-6879(79)68031-x

  • Szostak JW, Wu R Unequal crossing over in the ribosomal DNA of Saccharomyces cerevisiae. Nature. 1980;284(5755):426-30 - PMID: 6987539 - DOI: 10.1038/284426a0

  • Szostak JW, Wu R Insertion of a genetic marker into the ribosomal DNA of yeast. Plasmid. 1979;2(4):536-54 - PMID: 394173 - DOI: 10.1016/0147-619x(79)90053-2

  • Szostak JW, Stiles JI, Bahl CP, Wu R Specific binding of a synthetic oligodeoxyribonucleotide to yeast cytochrome c mRNA. Nature. 1977;265(5589):61-3 - PMID: 189200 - DOI: 10.1038/265061a0