Publications

Evolution of genes and genomes on the Drosophila phylogeny.

Drosophila 12 Genomes Consortium, Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, Kaufman TC, Kellis M, Gelbart W, Iyer VN, Pollard DA, Sackton TB, Larracuente AM, Singh ND, Abad JP, Abt DN, Adryan B, Aguade M, Akashi H, Anderson WW, Aquadro CF, Ardell DH, Arguello R, Artieri CG, Barbash DA, Barker D, Barsanti P, Batterham P, Batzoglou S, Begun D, Bhutkar A, Blanco E, Bosak SA, Bradley RK, Brand AD, Brent MR, Brooks AN, Brown RH, Butlin RK, Caggese C, Calvi BR, Bernardo de Car ...
Nature. 2007;450(7167):203-18 - PMID: 17994087

DLGH1 is a negative regulator of T-lymphocyte proliferation.

Stephenson LM, Sammut B, Graham DB, Chan-Wang J, Brim KL, Huett AS, Miletic AV, Kloeppel T, Landry A, Xavier R, Swat W
Mol Cell Biol. 2007;27(21):7574-81 - PMID: 17724087 - PMCID: PMC2169038

Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development.

Cotta-de-Almeida V, Westerberg L, Maillard MH, Onaldi D, Wachtel H, Meelu P, Chung UI, Xavier R, Alt FW, Snapper SB
Proc Natl Acad Sci U S A. 2007;104(39):15424-9 - PMID: 17878299 - PMCID: PMC2000553

Glucose signaling through nuclear hexokinase1 complex in Arabidopsis.

Cho YH, Yoo SD, Sheen J
Plant Signal Behav. 2007;2(2):123-4 - PMID: 19704756 - PMCID: PMC2633915

Nuclear actions in innate immune signaling.

Sheen J, He P
Cell. 2007;128(5):821-3 - PMID: 17350565

Elicitation and suppression of microbe-associated molecular pattern-triggered immunity in plant-microbe interactions.

He P, Shan L, Sheen J
Cell Microbiol. 2007;9(6):1385-96 - PMID: 17451411

Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis.

Yoo SD, Cho YH, Sheen J
Nat Protoc. 2007;2(7):1565-72 - PMID: 17585298

A central integrator of transcription networks in plant stress and energy signalling.

Baena-González E, Rolland F, Thevelein JM, Sheen J
Nature. 2007;448(7156):938-42 - PMID: 17671505

The N-terminal region of Pseudomonas type III effector AvrPtoB elicits Pto-dependent immunity and has two distinct virulence determinants.

Xiao F, He P, Abramovitch RB, Dawson JE, Nicholson LK, Sheen J, Martin GB
Plant J. 2007;52(4):595-614 - PMID: 17764515 - PMCID: PMC2265002

Advances in cytokinin signaling.

Müller B, Sheen J
Science. 2007;318(5847):68-9 - PMID: 17916725

Cytokinin signaling pathway.

Müller B, Sheen J
Sci STKE. 2007;2007(407):cm4 - PMID: 17925575

Arabidopsis cytokinin signaling pathway.

Müller B, Sheen J
Sci STKE. 2007;2007(407):cm5 - PMID: 17925576

Intercepting host MAPK signaling cascades by bacterial type III effectors.

Shan L, He P, Sheen J
Cell Host Microbe. 2007;1(3):167-74 - PMID: 18005696

Pseudomonas syringae type III effector AvrRpt2 alters Arabidopsis thaliana auxin physiology.

Chen Z, Agnew JL, Cohen JD, He P, Shan L, Sheen J, Kunkel BN
Proc Natl Acad Sci U S A. 2007;104(50):20131-6 - PMID: 18056646 - PMCID: PMC2148434

The bacterial two-hybrid system as a reporter system for analyzing protein-protein interactions.

Giesecke AV, Joung JK
CSH Protoc. 2007;2007:pdb.prot4672 - PMID: 21357036

Antifungal chemical compounds identified using a C. elegans pathogenicity assay.

Breger J, Fuchs BB, Aperis G, Moy TI, Ausubel FM, Mylonakis E
PLoS Pathog. 2007;3(2):e18 - PMID: 17274686 - PMCID: PMC1790726

Virstatin inhibits dimerization of the transcriptional activator ToxT.

Shakhnovich EA, Hung DT, Pierson E, Lee K, Mekalanos JJ
Proc Natl Acad Sci U S A. 2007;104(7):2372-7 - PMID: 17283330 - PMCID: PMC1892951

Retinol-binding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without type 2 diabetes.

Gavi S, Stuart LM, Kelly P, Melendez MM, Mynarcik DC, Gelato MC, McNurlan MA
J Clin Endocrinol Metab. 2007;92(5):1886-90 - PMID: 17299074

Genetic etiology of isolated low HDL syndrome: incidence and heterogeneity of efflux defects.

Kiss RS, Kavaslar N, Okuhira K, Freeman MW, Walter S, Milne RW, McPherson R, Marcel YL
Arterioscler Thromb Vasc Biol. 2007;27(5):1139-45 - PMID: 17303779

2',3'-Dideoxy-3'-thionucleoside triphosphates: syntheses and polymerase substrate activities.

Meena , Sam M, Pierce K, Szostak JW, McLaughlin LW
Org Lett. 2007;9(6):1161-3 - PMID: 17319676

Standard operating procedures for the clinical management of patients enrolled in a prospective study of Inflammation and the Host Response to Thermal Injury.

Silver GM, Klein MB, Herndon DN, Gamelli RL, Gibran NS, Altstein L, McDonald-Smith GP, Tompkins RG, Hunt JL,
J Burn Care Res. 2007;28(2):222-30 - PMID: 17351437

Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs.

Hayes GD, Ruvkun G
Cold Spring Harb Symp Quant Biol. 2007;71:21-7 - PMID: 17381276

Resistance to Botrytis cinerea induced in Arabidopsis by elicitors is independent of salicylic acid, ethylene, or jasmonate signaling but requires PHYTOALEXIN DEFICIENT3.

Ferrari S, Galletti R, Denoux C, De Lorenzo G, Ausubel FM, Dewdney J
Plant Physiol. 2007;144(1):367-79 - PMID: 17384165 - PMCID: PMC1913806

Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly.

Wright DA, Thibodeau-Beganny S, Sander JD, Winfrey RJ, Hirsh AS, Eichtinger M, Fu F, Porteus MH, Dobbs D, Voytas DF, Joung JK
Nat Protoc. 2007;1(3):1637-52 - PMID: 17406455

Lifespan regulation by evolutionarily conserved genes essential for viability.

Curran SP, Ruvkun G
PLoS Genet. 2007;3(4):e56 - PMID: 17411345 - PMCID: PMC1847696

The practice of venous thromboembolism prophylaxis in the major trauma patient.

Nathens AB, McMurray MK, Cuschieri J, Durr EA, Moore EE, Bankey PE, Freeman B, Harbrecht BG, Johnson JL, Minei JP, McKinley BA, Moore FA, Shapiro MB, West MA, Tompkins RG, Maier RV
J Trauma. 2007;62(3):557-62; discussion 562-3 - PMID: 17414328

The association between fluid administration and outcome following major burn: a multicenter study.

Klein MB, Hayden D, Elson C, Nathens AB, Gamelli RL, Gibran NS, Herndon DN, Arnoldo B, Silver G, Schoenfeld D, Tompkins RG
Ann Surg. 2007;245(4):622-8 - PMID: 17414612 - PMCID: PMC1877030

A microchip approach for practical label-free CD4+ T-cell counting of HIV-infected subjects in resource-poor settings.

Cheng X, Irimia D, Dixon M, Ziperstein JC, Demirci U, Zamir L, Tompkins RG, Toner M, Rodriguez WR
J Acquir Immune Defic Syndr. 2007;45(3):257-61 - PMID: 17414933

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.

Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L, Nicolae DL, Regueiro M, Schumm LP, Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR
Nat Genet. 2007;39(5):596-604 - PMID: 17435756 - PMCID: PMC2757939

Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses.

Begun J, Gaiani JM, Rohde H, Mack D, Calderwood SB, Ausubel FM, Sifri CD
PLoS Pathog. 2007;3(4):e57 - PMID: 17447841 - PMCID: PMC1853117

Molecular pathogenesis of inflammatory bowel disease: genotypes, phenotypes and personalized medicine.

Goyette P, Labbé C, Trinh TT, Xavier RJ, Rioux JD
Ann Med. 2007;39(3):177-99 - PMID: 17457716

Functional information and the emergence of biocomplexity.

Hazen RM, Griffin PL, Carothers JM, Szostak JW
Proc Natl Acad Sci U S A. 2007;104 Suppl 1:8574-81 - PMID: 17494745 - PMCID: PMC1876432

Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization.

Smith MD, Rosenow MA, Wang M, Allen JP, Szostak JW, Chaput JC
PLoS One. 2007;2(5):e467 - PMID: 17520026 - PMCID: PMC1867856

Zinc Finger Targeter (ZiFiT): an engineered zinc finger/target site design tool.

Sander JD, Zaback P, Joung JK, Voytas DF, Dobbs D
Nucleic Acids Res. 2007;35(Web Server issue):W599-605 - PMID: 17526515 - PMCID: PMC1933188

Characterization of the integrated filamentous phage Pf5 and its involvement in small-colony formation.

Mooij MJ, Drenkard E, Llamas MA, Vandenbroucke-Grauls CM, Savelkoul PH, Ausubel FM, Bitter W
Microbiology. 2007;153(Pt 6):1790-8 - PMID: 17526836 - PMCID: PMC3820363

Profiling the DNA-binding specificities of engineered Cys2His2 zinc finger domains using a rapid cell-based method.

Meng X, Thibodeau-Beganny S, Jiang T, Joung JK, Wolfe SA
Nucleic Acids Res. 2007;35(11):e81 - PMID: 17537811 - PMCID: PMC1920264

General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines.

Kueng HJ, Leb VM, Haiderer D, Raposo G, Thery C, Derdak SV, Schmetterer KG, Neunkirchner A, Sillaber C, Seed B, Pickl WF
J Virol. 2007;81(16):8666-76 - PMID: 17537846 - PMCID: PMC1951353

L-arginine attenuates acute lung injury after smoke inhalation and burn injury in sheep.

Murakami K, Enkhbaatar P, Yu YM, Traber LD, Cox RA, Hawkins HK, Tompkins RG, Herndon D, Traber DL
Shock. 2007;28(4):477-83 - PMID: 17558346

Structure and evolutionary analysis of a non-biological ATP-binding protein.

Mansy SS, Zhang J, Kümmerle R, Nilsson M, Chou JJ, Szostak JW, Chaput JC
J Mol Biol. 2007;371(2):501-13 - PMID: 17583732

BifA, a cyclic-Di-GMP phosphodiesterase, inversely regulates biofilm formation and swarming motility by Pseudomonas aeruginosa PA14.

Kuchma SL, Brothers KM, Merritt JH, Liberati NT, Ausubel FM, O'Toole GA
J Bacteriol. 2007;189(22):8165-78 - PMID: 17586641 - PMCID: PMC2168662

CD36 signals to the actin cytoskeleton and regulates microglial migration via a p130Cas complex.

Stuart LM, Bell SA, Stewart CR, Silver JM, Richard J, Goss JL, Tseng AA, Zhang A, El Khoury JB, Moore KJ
J Biol Chem. 2007;282(37):27392-401 - PMID: 17623670

Unravelling the pathogenesis of inflammatory bowel disease.

Xavier RJ, Podolsky DK
Nature. 2007;448(7152):427-34 - PMID: 17653185

Exploiting amoeboid and non-vertebrate animal model systems to study the virulence of human pathogenic fungi.

Mylonakis E, Casadevall A, Ausubel FM
PLoS Pathog. 2007;3(7):e101 - PMID: 17676994 - PMCID: PMC1933451

Selection and evolution of enzymes from a partially randomized non-catalytic scaffold.

Seelig B, Szostak JW
Nature. 2007;448(7155):828-31 - PMID: 17700701 - PMCID: PMC4476047

Targeting virulence: a new paradigm for antimicrobial therapy.

Clatworthy AE, Pierson E, Hung DT
Nat Chem Biol. 2007;3(9):541-8 - PMID: 17710100

Gravity force transduced by the MEC-4/MEC-10 DEG/ENaC channel modulates DAF-16/FoxO activity in Caenorhabditis elegans.

Kim N, Dempsey CM, Kuan CJ, Zoval JV, O'Rourke E, Ruvkun G, Madou MJ, Sze JY
Genetics. 2007;177(2):835-45 - PMID: 17720915 - PMCID: PMC2034647

Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template.

Tsai CH, Chen J, Szostak JW
Proc Natl Acad Sci U S A. 2007;104(37):14598-603 - PMID: 17785419 - PMCID: PMC1976233

AKAP13, a RhoA GTPase-specific guanine exchange factor, is a novel regulator of TLR2 signaling.

Shibolet O, Giallourakis C, Rosenberg I, Mueller T, Xavier RJ, Podolsky DK
J Biol Chem. 2007;282(48):35308-17 - PMID: 17878165

An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides.

Hartman MC, Josephson K, Lin CW, Szostak JW
PLoS One. 2007;2(10):e972 - PMID: 17912351 - PMCID: PMC1989143

American Burn Association consensus conference to define sepsis and infection in burns.

Greenhalgh DG, Saffle JR, Holmes JH, Gamelli RL, Palmieri TL, Horton JW, Tompkins RG, Traber DL, Mozingo DW, Deitch EA, Goodwin CW, Herndon DN, Gallagher JJ, Sanford AP, Jeng JC, Ahrenholz DH, Neely AN, O'Mara MS, Wolf SE, Purdue GF, Garner WL, Yowler CJ, Latenser BA,
J Burn Care Res. 2007;28(6):776-90 - PMID: 17925660

Inhibitors of pathogen intercellular signals as selective anti-infective compounds.

Lesic B, Lépine F, Déziel E, Zhang J, Zhang Q, Padfield K, Castonguay MH, Milot S, Stachel S, Tzika AA, Tompkins RG, Rahme LG
PLoS Pathog. 2007;3(9):1229-39 - PMID: 17941706 - PMCID: PMC2323289

DLG1 is an anchor for the E3 ligase MARCH2 at sites of cell-cell contact.

Cao Z, Huett A, Kuballa P, Giallourakis C, Xavier RJ
Cell Signal. 2007;20(1):73-82 - PMID: 17980554 - PMCID: PMC2257480

Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants.

Samuelson AV, Carr CE, Ruvkun G
Genes Dev. 2007;21(22):2976-94 - PMID: 18006689 - PMCID: PMC2049198

A whole-genome RNAi Screen for C. elegans miRNA pathway genes.

Parry DH, Xu J, Ruvkun G
Curr Biol. 2007;17(23):2013-22 - PMID: 18023351 - PMCID: PMC2211719

Continuous inertial focusing, ordering, and separation of particles in microchannels.

Di Carlo D, Irimia D, Tompkins RG, Toner M
Proc Natl Acad Sci U S A. 2007;104(48):18892-7 - PMID: 18025477 - PMCID: PMC2141878

DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases.

Cornu TI, Thibodeau-Beganny S, Guhl E, Alwin S, Eichtinger M, Joung JK, Joung JK, Cathomen T
Mol Ther. 2007;16(2):352-8 - PMID: 18026168

Molecular and functional analysis of the antigen receptor of Art v 1-specific helper T lymphocytes.

Leb VM, Jahn-Schmid B, Schmetterer KG, Kueng HJ, Haiderer D, Neunkirchner A, Fischer GF, Nissler K, Hartl A, Thalhamer J, Bohle B, Seed B, Pickl WF
J Allergy Clin Immunol. 2007;121(1):64-71 - PMID: 18037161

Miniprimer PCR, a new lens for viewing the microbial world.

Isenbarger TA, Finney M, Ríos-Velázquez C, Handelsman J, Ruvkun G
Appl Environ Microbiol. 2007;74(3):840-9 - PMID: 18083877 - PMCID: PMC2227730

Isolation of rare circulating tumour cells in cancer patients by microchip technology.

Nagrath S, Sequist LV, Maheswaran S, Bell DW, Irimia D, Ulkus L, Smith MR, Kwak EL, Digumarthy S, Muzikansky A, Ryan P, Balis UJ, Tompkins RG, Haber DA, Toner M
Nature. 2007;450(7173):1235-9 - PMID: 18097410 - PMCID: PMC3090667

Involvement of skeletal muscle gene regulatory network in susceptibility to wound infection following trauma.

Apidianakis Y, Mindrinos MN, Xiao W, Tegos GP, Papisov MI, Hamblin MR, Davis RW, Tompkins RG, Rahme LG
PLoS One. 2007;2(12):e1356 - PMID: 18159239 - PMCID: PMC2131783

Bile acids stimulate biofilm formation in Vibrio cholerae.

Hung DT, Zhu J, Sturtevant D, Mekalanos JJ
Mol Microbiol. 2006;59(1):193-201 - PMID: 16359328

Statins, cholesterol, and the prevention of coronary heart disease

MW Freeman
FASEB J. 2006;20(2):200-201

Scavenger receptors in atherosclerosis

MW Freeman and KJ Moore
Arterioscler Thromb Vasc Biol. 2006;8:1702-1711

Lipid Disorders and Coronary Heart Disease. In: Runge, MS and Patterson, W Eds.

MW Freeman
Molecular Medicine. 2006;:ePub

A genome-wide map of diversity in Plasmodium falciparum.

Volkman SK, Sabeti PC, DeCaprio D, Neafsey DE, Schaffner SF, Milner DA, Daily JP, Sarr O, Ndiaye D, Ndir O, Mboup S, Duraisingh MT, Lukens A, Derr A, Stange-Thomann N, Waggoner S, Onofrio R, Ziaugra L, Mauceli E, Gnerre S, Jaffe DB, Zainoun J, Wiegand RC, Birren BW, Hartl DL, Galagan JE, Lander ES, Wirth DF
Nat Genet. 2006;39(1):113-9 - PMID: 17159979

Isolation and analysis of lipid rafts in cell-cell interactions.

Landry A, Xavier R
Methods Mol Biol. 2006;341:251-82 - PMID: 16799204

Nore1B regulates TCR signaling via Ras and Carma1.

Ishiguro K, Avruch J, Landry A, Qin S, Ando T, Goto H, Xavier R
Cell Signal. 2006;18(10):1647-54 - PMID: 16520020 - PMCID: PMC3204664

A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands.

Giallourakis C, Cao Z, Green T, Wachtel H, Xie X, Lopez-Illasaca M, Daly M, Rioux J, Xavier R
Genome Res. 2006;16(8):1056-72 - PMID: 16825666 - PMCID: PMC1524865

Immune cell transcriptome datasets reveal novel leukocyte subset-specific genes and genes associated with allergic processes.

Liu SM, Xavier R, Good KL, Chtanova T, Newton R, Sisavanh M, Zimmer S, Deng C, Silva DG, Frost MJ, Tangye SG, Rolph MS, Mackay CR
J Allergy Clin Immunol. 2006;118(2):496-503 - PMID: 16890777

Paeonol attenuates TNBS-induced colitis by inhibiting NF-kappaB and STAT1 transactivation.

Ishiguro K, Ando T, Maeda O, Hasegawa M, Kadomatsu K, Ohmiya N, Niwa Y, Xavier R, Goto H
Toxicol Appl Pharmacol. 2006;217(1):35-42 - PMID: 16928387

Centaurin beta1 down-regulates nucleotide-binding oligomerization domains 1- and 2-dependent NF-kappaB activation.

Yamamoto-Furusho JK, Barnich N, Xavier R, Hisamatsu T, Podolsky DK
J Biol Chem. 2006;281(47):36060-70 - PMID: 17005562

Bcl10 is phosphorylated on Ser138 by Ca2+/calmodulin-dependent protein kinase II.

Ishiguro K, Ando T, Goto H, Xavier R
Mol Immunol. 2006;44(8):2095-100 - PMID: 17052756

Vav proteins control MyD88-dependent oxidative burst.

Miletic AV, Graham DB, Montgrain V, Fujikawa K, Kloeppel T, Brim K, Weaver B, Schreiber R, Xavier R, Swat W
Blood. 2006;109(8):3360-8 - PMID: 17158234 - PMCID: PMC1852252

Vav proteins control MyD88-dependent oxidative burst.

Miletic AV, Graham DB, Montgrain V, Fujikawa K, Kloeppel T, Brim K, Weaver B, Schreiber R, Xavier R, Swat W
Blood. 2006;109(8):3360-8 - PMID: 17158234 - PMCID: PMC1852252

Ancient signals: comparative genomics of plant MAPK and MAPKK gene families.

Hamel LP, Nicole MC, Sritubtim S, Morency MJ, Ellis M, Ehlting J, Beaudoin N, Barbazuk B, Klessig D, Lee J, Martin G, Mundy J, Ohashi Y, Scheel D, Sheen J, Xing T, Zhang S, Seguin A, Ellis BE
Trends Plant Sci. 2006;11(4):192-8 - PMID: 16537113

Sugar sensing and signaling in plants: conserved and novel mechanisms.

Rolland F, Baena-Gonzalez E, Sheen J
Annu Rev Plant Biol. 2006;57:675-709 - PMID: 16669778

Specific bacterial suppressors of MAMP signaling upstream of MAPKKK in Arabidopsis innate immunity.

He P, Shan L, Lin NC, Martin GB, Kemmerling B, Nürnberger T, Sheen J
Cell. 2006;125(3):563-75 - PMID: 16678099

Regulatory functions of nuclear hexokinase1 complex in glucose signaling.

Cho YH, Yoo SD, Sheen J
Cell. 2006;127(3):579-89 - PMID: 17081979

The use of protoplasts to study innate immune responses.

He P, Shan L, Sheen J
Methods Mol Biol. 2006;354:1-9 - PMID: 17172739

Collectins: opsonins for apoptotic cells and regulators of inflammation.

Stuart LM, Henson PM, Vandivier RW
Curr Dir Autoimmun. 2006;9:143-61 - PMID: 16394659

Clarifications on miRNA and cancer.

Ruvkun G
Science. 2006;311(5757):36-7 - PMID: 16400132

Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways.

Duchaine TF, Wohlschlegel JA, Kennedy S, Bei Y, Conte D, Pang K, Brownell DR, Harding S, Mitani S, Ruvkun G, Yates JR, Mello CC
Cell. 2006;124(2):343-54 - PMID: 16439208

Expression cloning screen for modifiers of amyloid precursor protein shedding.

Schöbel S, Neumann S, Seed B, Lichtenthaler SF
Int J Dev Neurosci. 2006;24(2-3):141-8 - PMID: 16446073

Statins, cholesterol, and the prevention of coronary heart disease.

Freeman MW
FASEB J. 2006;20(2):200-1 - PMID: 16449790

Polygenic control of Caenorhabditis elegans fat storage.

Mak HY, Nelson LS, Basson M, Johnson CD, Ruvkun G
Nat Genet. 2006;38(3):363-8 - PMID: 16462744

An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants.

Liberati NT, Urbach JM, Miyata S, Lee DG, Drenkard E, Wu G, Villanueva J, Wei T, Ausubel FM
Proc Natl Acad Sci U S A. 2006;103(8):2833-8 - PMID: 16477005 - PMCID: PMC1413827

Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence.

Kulasakara H, Lee V, Brencic A, Liberati N, Urbach J, Miyata S, Lee DG, Neely AN, Hyodo M, Hayakawa Y, Ausubel FM, Lory S
Proc Natl Acad Sci U S A. 2006;103(8):2839-44 - PMID: 16477007 - PMCID: PMC1413825

Directed evolution of ATP binding proteins from a zinc finger domain by using mRNA display.

Cho GS, Szostak JW
Chem Biol. 2006;13(2):139-47 - PMID: 16492562

Solution structure of an informationally complex high-affinity RNA aptamer to GTP.

Carothers JM, Davis JH, Chou JJ, Szostak JW
RNA. 2006;12(4):567-79 - PMID: 16510427 - PMCID: PMC1421093

Counter-selectable marker for bacterial-based interaction trap systems.

Meng X, Smith RM, Giesecke AV, Joung JK, Wolfe SA
Biotechniques. 2006;40(2):179-84 - PMID: 16526407

Enzymatic aminoacylation of tRNA with unnatural amino acids.

Hartman MC, Josephson K, Szostak JW
Proc Natl Acad Sci U S A. 2006;103(12):4356-61 - PMID: 16537388 - PMCID: PMC1450175

Nonmetabolizable glucose compounds impart cryotolerance to primary rat hepatocytes.

Sugimachi K, Roach KL, Rhoads DB, Tompkins RG, Toner M
Tissue Eng. 2006;12(3):579-88 - PMID: 16579691

A genetic interaction between the vesicular acetylcholine transporter VAChT/UNC-17 and synaptobrevin/SNB-1 in C. elegans.

Sandoval GM, Duerr JS, Hodgkin J, Rand JB, Ruvkun G
Nat Neurosci. 2006;9(5):599-601 - PMID: 16604067

Adipocyte apoptosis after burn injury is associated with altered fat metabolism.

Yasuhara S, Kaneki M, Sugita H, Sugita M, Asai A, Sahani N, Chon JY, Tompkins RG, Martyn JA
J Burn Care Res. 2006;27(3):367-76 - PMID: 16679908

High dynamic range characterization of the trauma patient plasma proteome.

Liu T, Qian WJ, Gritsenko MA, Xiao W, Moldawer LL, Kaushal A, Monroe ME, Varnum SM, Moore RJ, Purvine SO, Maier RV, Davis RW, Tompkins RG, Camp DG, Smith RD,
Mol Cell Proteomics. 2006;5(10):1899-913 - PMID: 16684767 - PMCID: PMC1783978

Scavenger receptors in atherosclerosis: beyond lipid uptake.

Moore KJ, Freeman MW
Arterioscler Thromb Vasc Biol. 2006;26(8):1702-11 - PMID: 16728653

Synthetic protein-protein interaction domains created by shuffling Cys2His2 zinc-fingers.

Giesecke AV, Fang R, Joung JK
Mol Syst Biol. 2006;2:2006.2011 - PMID: 16732192 - PMCID: PMC1681485

Ribosomal synthesis of dehydroalanine-containing peptides.

Seebeck FP, Szostak JW
J Am Chem Soc. 2006;128(22):7150-1 - PMID: 16734454 - PMCID: PMC2572134

Prevention and control of pests and diseases.

Bush J, Jander G, Ausubel FM
Methods Mol Biol. 2006;323:13-25 - PMID: 16739564

CARMA1 is critical for the development of allergic airway inflammation in a murine model of asthma.

Medoff BD, Seed B, Jackobek R, Zora J, Yang Y, Luster AD, Xavier R
J Immunol. 2006;176(12):7272-7 - PMID: 16751370

Negative chemical ionization gas chromatography/mass spectrometry to quantify urinary 3-methylhistidine: application to burn injury.

Beffa DC, Carter EA, Lu XM, Yu YM, Prelack K, Sheridan RL, Young VR, Fischman AJ, Tompkins RG
Anal Biochem. 2006;355(1):95-101 - PMID: 16762308

SLIRP, a small SRA binding protein, is a nuclear receptor corepressor.

Hatchell EC, Colley SM, Beveridge DJ, Epis MR, Stuart LM, Giles KM, Redfern AD, Miles LE, Barker A, MacDonald LM, Arthur PG, Lui JC, Golding JL, McCulloch RK, Metcalf CB, Wilce JA, Wilce MC, Lanz RB, O'Malley BW, Leedman PJ
Mol Cell. 2006;22(5):657-68 - PMID: 16762838

Aptamers selected for higher-affinity binding are not more specific for the target ligand.

Carothers JM, Oestreich SC, Szostak JW
J Am Chem Soc. 2006;128(24):7929-37 - PMID: 16771507 - PMCID: PMC4287982

Treatment of fulminant hepatic failure in rats using a bioartificial liver device containing porcine hepatocytes producing interleukin-1 receptor antagonist.

Shinoda M, Tilles AW, Wakabayashi G, Takayanagi A, Harada H, Obara H, Suganuma K, Berthiaume F, Shimazu M, Shimizu N, Kitajima M, Tompkins RG, Toner M, Yarmush ML
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Identification of novel antimicrobials using a live-animal infection model.

Moy TI, Ball AR, Anklesaria Z, Casadei G, Lewis K, Ausubel FM
Proc Natl Acad Sci U S A. 2006;103(27):10414-9 - PMID: 16801562 - PMCID: PMC1482800

Ca2+/calmodulin-dependent protein kinase II is a modulator of CARMA1-mediated NF-kappaB activation.

Ishiguro K, Green T, Rapley J, Wachtel H, Giallourakis C, Landry A, Cao Z, Lu N, Takafumi A, Goto H, Daly MJ, Xavier RJ
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Chemical biology and bacteria: not simply a matter of life or death.

Hung DT, Rubin EJ
Curr Opin Chem Biol. 2006;10(4):321-6 - PMID: 16814591

Inflammation and the host response to injury: an overview of the multicenter study of the genomic and proteomic response to burn injury.

Klein MB, Silver G, Gamelli RL, Gibran NS, Herndon DN, Hunt JL, Tompkins RG,
J Burn Care Res. 2006;27(4):448-51 - PMID: 16819346

Panning of multiple subsets of leukocytes on antibody-decorated poly(ethylene) glycol-coated glass slides.

Sekine K, Revzin A, Tompkins RG, Toner M
J Immunol Methods. 2006;313(1-2):96-109 - PMID: 16822521

A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies.

Kuo WP, Liu F, Trimarchi J, Punzo C, Lombardi M, Sarang J, Whipple ME, Maysuria M, Serikawa K, Lee SY, McCrann D, Kang J, Shearstone JR, Burke J, Park DJ, Wang X, Rector TL, Ricciardi-Castagnoli P, Perrin S, Choi S, Bumgarner R, Kim JH, Short GF, Freeman MW, Seed B, Jensen R, Church GM, Hovig E, Cepko CL, Park P, Ohno-Machado L, Jenssen TK
Nat Biotechnol. 2006;24(7):832-40 - PMID: 16823376

Putting food on the public health table: Making food security relevant to regional health authorities.

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Can J Public Health. 2006;97(3):233-6 - PMID: 16827415

Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling.

Hu PJ, Xu J, Ruvkun G
PLoS Genet. 2006;2(7):e99 - PMID: 16839187 - PMCID: PMC1487177

Microfluidic isolation of leukocytes from whole blood for phenotype and gene expression analysis.

Sethu P, Moldawer LL, Mindrinos MN, Scumpia PO, Tannahill CL, Wilhelmy J, Efron PA, Brownstein BH, Tompkins RG, Toner M
Anal Chem. 2006;78(15):5453-61 - PMID: 16878882

Peroxidase-dependent apoplastic oxidative burst in Arabidopsis required for pathogen resistance.

Bindschedler LV, Dewdney J, Blee KA, Stone JM, Asai T, Plotnikov J, Denoux C, Hayes T, Gerrish C, Davies DR, Ausubel FM, Bolwell GP
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Mineral surface directed membrane assembly.

Hanczyc MM, Mansy SS, Szostak JW
Orig Life Evol Biosph. 2006;37(1):67-82 - PMID: 16909329

Local and distant burn injury alter immuno-inflammatory gene expression in skeletal muscle.

Padfield KE, Zhang Q, Gopalan S, Tzika AA, Mindrinos MN, Tompkins RG, Rahme LG
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Direct stimulation of T lymphocytes by immunosomes: virus-like particles decorated with T cell receptor/CD3 ligands plus costimulatory molecules.

Derdak SV, Kueng HJ, Leb VM, Neunkirchner A, Schmetterer KG, Bielek E, Majdic O, Knapp W, Seed B, Pickl WF
Proc Natl Acad Sci U S A. 2006;103(35):13144-9 - PMID: 16924110 - PMCID: PMC1559767

Requirements for apoptotic cell contact in regulation of macrophage responses.

Lucas M, Stuart LM, Zhang A, Hodivala-Dilke K, Febbraio M, Silverstein R, Savill J, Lacy-Hulbert A
J Immunol. 2006;177(6):4047-54 - PMID: 16951368

A genomewide search for ribozymes reveals an HDV-like sequence in the human CPEB3 gene.

Salehi-Ashtiani K, Lupták A, Litovchick A, Szostak JW
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Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging.

Blackburn EH, Greider CW, Szostak JW
Nat Med. 2006;12(10):1133-8 - PMID: 17024208

Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways.

Laudanski K, Miller-Graziano C, Xiao W, Mindrinos MN, Richards DR, De A, Moldawer LL, Maier RV, Bankey P, Baker HV, Brownstein BH, Cobb JP, Calvano SE, Davis RW, Tompkins RG
Proc Natl Acad Sci U S A. 2006;103(42):15564-9 - PMID: 17032758 - PMCID: PMC1592643

Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial.

Lee DG, Urbach JM, Wu G, Liberati NT, Feinbaum RL, Miyata S, Diggins LT, He J, Saucier M, Déziel E, Friedman L, Li L, Grills G, Montgomery K, Kucherlapati R, Rahme LG, Ausubel FM
Genome Biol. 2006;7(10):R90 - PMID: 17038190 - PMCID: PMC1794565

Detection of broadly expressed neuronal genes in C. elegans.

Ruvinsky I, Ohler U, Burge CB, Ruvkun G
Dev Biol. 2006;302(2):617-26 - PMID: 17046742

The mir-84 and let-7 paralogous microRNA genes of Caenorhabditis elegans direct the cessation of molting via the conserved nuclear hormone receptors NHR-23 and NHR-25.

Hayes GD, Frand AR, Ruvkun G
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Glycerol nucleoside triphosphates: synthesis and polymerase substrate activities.

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A bioartificial liver device secreting interleukin-1 receptor antagonist for the treatment of hepatic failure in rats.

Shinoda M, Tilles AW, Kobayashi N, Wakabayashi G, Takayanagi A, Totsugawa T, Harada H, Obara H, Suganuma K, Berthiaume F, Shimazu M, Shimizu N, Tanaka N, Kitajima M, Tompkins RG, Toner M, Yarmush ML
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Uncoupling protein 3 expression and intramyocellular lipid accumulation by NMR following local burn trauma.

Zhang Q, Cao H, Astrakas LG, Mintzopoulos D, Mindrinos MN, Schulz J, Tompkins RG, Rahme LG, Tzika AA
Int J Mol Med. 2006;18(6):1223-9 - PMID: 17089030

p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans.

Troemel ER, Chu SW, Reinke V, Lee SS, Ausubel FM, Kim DH
PLoS Genet. 2006;2(11):e183 - PMID: 17096597 - PMCID: PMC1635533

ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol.

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J Lipid Res. 2006;48(3):621-32 - PMID: 17142808

A systems biology analysis of the Drosophila phagosome.

Stuart LM, Boulais J, Charriere GM, Hennessy EJ, Brunet S, Jutras I, Goyette G, Rondeau C, Letarte S, Huang H, Ye P, Morales F, Kocks C, Bader JS, Desjardins M, Ezekowitz RA
Nature. 2006;445(7123):95-101 - PMID: 17151602

Prospects for plant-derived antibacterials.

Lewis K, Ausubel FM
Nat Biotechnol. 2006;24(12):1504-7 - PMID: 17160050

Conjugating berberine to a multidrug efflux pump inhibitor creates an effective antimicrobial.

Ball AR, Casadei G, Samosorn S, Bremner JB, Ausubel FM, Moy TI, Lewis K
ACS Chem Biol. 2006;1(9):594-600 - PMID: 17168555

Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter.

Mahoney ZX, Sammut B, Xavier RJ, Cunningham J, Go G, Brim KL, Stappenbeck TS, Miner JH, Swat W
Proc Natl Acad Sci U S A. 2006;103(52):19872-7 - PMID: 17172448 - PMCID: PMC1750896

Risk factors for coronary artery disease in patients with elevated high-density lipoprotein cholesterol.

DeFaria Yeh D, Freeman MW, Meigs JB, Grant RW
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A microfluidic device for practical label-free CD4(+) T cell counting of HIV-infected subjects.

Cheng X, Irimia D, Dixon M, Sekine K, Demirci U, Zamir L, Tompkins RG, Rodriguez W, Toner M
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Cryopreservation of isolated primary rat hepatocytes: enhanced survival and long-term hepatospecific function.

Sosef MN, Baust JM, Sugimachi K, Fowler A, Tompkins RG, Toner M
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Evolution of intrahepatic carbon, nitrogen, and energy metabolism in a D-galactosamine-induced rat liver failure model.

Yokoyama T, Banta S, Berthiaume F, Nagrath D, Tompkins RG, Yarmush ML
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Burn injury causes mitochondrial dysfunction in skeletal muscle.

Padfield KE, Astrakas LG, Zhang Q, Gopalan S, Dai G, Mindrinos MN, Tompkins RG, Rahme LG, Tzika AA
Proc Natl Acad Sci U S A. 2005;102(15):5368-73 - PMID: 15809440 - PMCID: PMC556259

Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma-induced apoptosis.

Astrakas LG, Goljer I, Yasuhara S, Padfield KE, Zhang Q, Gopalan S, Mindrinos MN, Dai G, Yu YM, Martyn JA, Tompkins RG, Rahme LG, Tzika AA
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Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation.

Zhang Q, Carter EA, Ma BY, White M, Fischman AJ, Tompkins RG
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A network-based analysis of systemic inflammation in humans.

Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho RJ, Chen RO, Brownstein BH, Cobb JP, Tschoeke SK, Miller-Graziano C, Moldawer LL, Mindrinos MN, Davis RW, Tompkins RG, Lowry SF,
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Application of genome-wide expression analysis to human health and disease.

Cobb JP, Mindrinos MN, Miller-Graziano C, Calvano SE, Baker HV, Xiao W, Laudanski K, Brownstein BH, Elson CM, Hayden DL, Herndon DN, Lowry SF, Maier RV, Schoenfeld DA, Moldawer LL, Davis RW, Tompkins RG, Baker HV, Bankey P, Billiar T, Brownstein BH, Calvano SE, Camp D, Chaudry I, Cobb JP, Davis RW, Elson CM, Freeman B, Gamelli R, Gibran N, Harbrecht B, Hayden DL, Heagy W, Heimbach D, Herndon DN, Horton J, Hunt J, Laudanski K, Lederer J, Lowry SF, Maier RV, Mannick J, McKinley B, Miller-Grazi ...
Proc Natl Acad Sci U S A. 2005;102(13):4801-6 - PMID: 15781863 - PMCID: PMC555033

A new approach for sequencing human IRS1 phosphotyrosine-containing peptides using CapLC-Q-TOF(micro).

Lu XM, Lu MY, Fischman AJ, Tompkins RG
J Mass Spectrom. 2005;40(5):599-607 - PMID: 15739155

Enrichment using antibody-coated microfluidic chambers in shear flow: model mixtures of human lymphocytes.

Sin A, Murthy SK, Revzin A, Tompkins RG, Toner M
Biotechnol Bioeng. 2005;91(7):816-26 - PMID: 16037988

Selective activation of peripheral blood T cell subsets by endotoxin infusion in healthy human subjects corresponds to differential chemokine activation.

De AK, Miller-Graziano CL, Calvano SE, Laudanski K, Lowry SF, Moldawer LL, Remick DG, Rajicic N, Schoenfeld D, Tompkins RG
J Immunol. 2005;175(9):6155-62 - PMID: 16237112

Site-specific detection of S-nitrosylated PKB alpha/Akt1 from rat soleus muscle using CapLC-Q-TOF(micro) mass spectrometry.

Lu XM, Lu M, Tompkins RG, Fischman AJ
J Mass Spectrom. 2005;40(9):1140-8 - PMID: 16041729

Quantitative proteome analysis of human plasma following in vivo lipopolysaccharide administration using 16O/18O labeling and the accurate mass and time tag approach.

Qian WJ, Monroe ME, Liu T, Jacobs JM, Anderson GA, Shen Y, Moore RJ, Anderson DJ, Zhang R, Calvano SE, Lowry SF, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Camp DG, Smith RD,
Mol Cell Proteomics. 2005;4(5):700-9 - PMID: 15753121 - PMCID: PMC1829297

Comparative proteome analyses of human plasma following in vivo lipopolysaccharide administration using multidimensional separations coupled with tandem mass spectrometry.

Qian WJ, Jacobs JM, Camp DG, Monroe ME, Moore RJ, Gritsenko MA, Calvano SE, Lowry SF, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Smith RD
Proteomics. 2005;5(2):572-84 - PMID: 15627965 - PMCID: PMC1781926

Significance analysis of time course microarray experiments.

Storey JD, Xiao W, Leek JT, Tompkins RG, Davis RW
Proc Natl Acad Sci U S A. 2005;102(36):12837-42 - PMID: 16141318 - PMCID: PMC1201697

The worm has turned--microbial virulence modeled in Caenorhabditis elegans.

Sifri CD, Begun J, Ausubel FM
Trends Microbiol. 2005;13(3):119-27 - PMID: 15737730

Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis.

Mylonakis E, Moreno R, El Khoury JB, Idnurm A, Heitman J, Calderwood SB, Ausubel FM, Diener A
Infect Immun. 2005;73(7):3842-50 - PMID: 15972469 - PMCID: PMC1168598

RESISTANCE TO FUSARIUM OXYSPORUM 1, a dominant Arabidopsis disease-resistance gene, is not race specific.

Diener AC, Ausubel FM
Genetics. 2005;171(1):305-21 - PMID: 15965251 - PMCID: PMC1456520

Pseudomonas syringae manipulates systemic plant defenses against pathogens and herbivores.

Cui J, Bahrami AK, Pringle EG, Hernandez-Guzman G, Bender CL, Pierce NE, Ausubel FM
Proc Natl Acad Sci U S A. 2005;102(5):1791-6 - PMID: 15657122 - PMCID: PMC547856

Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans.

Kim DH, Ausubel FM
Curr Opin Immunol. 2005;17(1):4-10 - PMID: 15653303

Mediation of pathogen resistance by exudation of antimicrobials from roots.

Bais HP, Prithiviraj B, Jha AK, Ausubel FM, Vivanco JM
Nature. 2005;434(7030):217-21 - PMID: 15759001

Are innate immune signaling pathways in plants and animals conserved?

Ausubel FM
Nat Immunol. 2005;6(10):973-9 - PMID: 16177805

A high-throughput, near-saturating screen for type III effector genes from Pseudomonas syringae.

Chang JH, Urbach JM, Law TF, Arnold LW, Hu A, Gombar S, Grant SR, Ausubel FM, Dangl JL
Proc Natl Acad Sci U S A. 2005;102(7):2549-54 - PMID: 15701698 - PMCID: PMC549004

Staphylococcus aureus virulence factors identified by using a high-throughput Caenorhabditis elegans-killing model.

Begun J, Sifri CD, Goldman S, Calderwood SB, Ausubel FM
Infect Immun. 2005;73(2):872-7 - PMID: 15664928 - PMCID: PMC547013

Scanning the human proteome for calmodulin-binding proteins.

Shen X, Valencia CA, Szostak JW, Szostak J, Dong B, Liu R
Proc Natl Acad Sci U S A. 2005;102(17):5969-74 - PMID: 15840729 - PMCID: PMC1087907

RNA catalysis in model protocell vesicles.

Chen IA, Salehi-Ashtiani K, Szostak JW
J Am Chem Soc. 2005;127(38):13213-9 - PMID: 16173749 - PMCID: PMC5072289

An in vitro selection system for TNA.

Ichida JK, Zou K, Horhota A, Yu B, McLaughlin LW, Szostak JW
J Am Chem Soc. 2005;127(9):2802-3 - PMID: 15740086 - PMCID: PMC5072288

Kinetic analysis of an efficient DNA-dependent TNA polymerase.

Horhota A, Zou K, Ichida JK, Yu B, McLaughlin LW, Szostak JW, Chaput JC
J Am Chem Soc. 2005;127(20):7427-34 - PMID: 15898792 - PMCID: PMC5042361

In vitro selection of RNA aptamers against a composite small molecule-protein surface.

Plummer KA, Carothers JM, Yoshimura M, Szostak JW, Verdine GL
Nucleic Acids Res. 2005;33(17):5602-10 - PMID: 16199752 - PMCID: PMC1240114

Semipermeable lipid bilayers exhibit diastereoselectivity favoring ribose.

Sacerdote MG, Szostak JW
Proc Natl Acad Sci U S A. 2005;102(17):6004-8 - PMID: 15831588 - PMCID: PMC556129

High fidelity TNA synthesis by Therminator polymerase.

Ichida JK, Horhota A, Zou K, McLaughlin LW, Szostak JW
Nucleic Acids Res. 2005;33(16):5219-25 - PMID: 16157867 - PMCID: PMC1214552

Shrink-wrap vesicles.

Fujikawa SM, Chen IA, Szostak JW
Langmuir. 2005;21(26):12124-9 - PMID: 16342983 - PMCID: PMC2548281

Synthesis of alpha-L-threofuranosyl nucleoside triphosphates (tNTPs).

Zou K, Horhota A, Yu B, Szostak JW, McLaughlin LW
Org Lett. 2005;7(8):1485-7 - PMID: 15816733 - PMCID: PMC5022784

Ribosomal synthesis of unnatural peptides.

Josephson K, Hartman MC, Szostak JW
J Am Chem Soc. 2005;127(33):11727-35 - PMID: 16104750

Phagocytosis: elegant complexity.

Stuart LM, Ezekowitz RA
Immunity. 2005;22(5):539-50 - PMID: 15894272

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila.

Kocks C, Cho JH, Nehme N, Ulvila J, Pearson AM, Meister M, Strom C, Conto SL, Hetru C, Stuart LM, Stehle T, Hoffmann JA, Reichhart JM, Ferrandon D, Rämet M, Ezekowitz RA
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Mannose-binding lectin-deficient mice display defective apoptotic cell clearance but no autoimmune phenotype.

Stuart LM, Takahashi K, Shi L, Savill J, Ezekowitz RA
J Immunol. 2005;174(6):3220-6 - PMID: 15749852

Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain.

Stuart LM, Deng J, Silver JM, Takahashi K, Tseng AA, Hennessy EJ, Ezekowitz RA, Moore KJ
J Cell Biol. 2005;170(3):477-85 - PMID: 16061696 - PMCID: PMC2171464

Repression of phase-variable cup gene expression by H-NS-like proteins in Pseudomonas aeruginosa.

Vallet-Gely I, Donovan KE, Fang R, Joung JK, Dove SL
Proc Natl Acad Sci U S A. 2005;102(31):11082-7 - PMID: 16043713 - PMCID: PMC1182424

A combined yeast/bacteria two-hybrid system: development and evaluation.

Serebriiskii IG, Fang R, Latypova E, Hopkins R, Vinson C, Joung JK, Golemis EA
Mol Cell Proteomics. 2005;4(6):819-26 - PMID: 15781424 - PMCID: PMC2670611

Bile acids induce cholera toxin expression in Vibrio cholerae in a ToxT-independent manner.

Hung DT, Mekalanos JJ
Proc Natl Acad Sci U S A. 2005;102(8):3028-33 - PMID: 15699331 - PMCID: PMC549475

Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization.

Hung DT, Shakhnovich EA, Pierson E, Mekalanos JJ
Science. 2005;310(5748):670-4 - PMID: 16223984

Identification of eosinophil lineage-committed progenitors in the murine bone marrow.

Iwasaki H, Mizuno S, Mayfield R, Shigematsu H, Arinobu Y, Seed B, Gurish MF, Takatsu K, Akashi K
J Exp Med. 2005;201(12):1891-7 - PMID: 15955840 - PMCID: PMC2212039

B cell maturation antigen, the receptor for a proliferation-inducing ligand and B cell-activating factor of the TNF family, induces antigen presentation in B cells.

Yang M, Hase H, Legarda-Addison D, Varughese L, Seed B, Ting AT
J Immunol. 2005;175(5):2814-24 - PMID: 16116167

Atherosclerosis and innate immunity signaling

Laberge MA, Moore KJ, and MW Freeman.
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Distinct roles of pattern recognition receptors CD14 and Toll-like receptor 4 in acute lung injury.

Jeyaseelan S, Chu HW, Young SK, Freeman MW, Worthen GS
Infect Immun. 2005;73(3):1754-63 - PMID: 15731076 - PMCID: PMC1064978

Efficacy and safety of the coadministration of ezetimibe with fenofibrate in patients with mixed hyperlipidaemia.

Farnier M, Freeman MW, Macdonell G, Perevozskaya I, Davies MJ, Mitchel YB, Gumbiner B,
Eur Heart J. 2005;26(9):897-905 - PMID: 15781429

Atherosclerosis and innate immune signaling.

Laberge MA, Moore KJ, Freeman MW
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Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment.

Heller EA, Liu E, Tager AM, Sinha S, Roberts JD, Koehn SL, Libby P, Aikawa ER, Chen JQ, Huang P, Freeman MW, Moore KJ, Luster AD, Gerszten RE
Circulation. 2005;112(4):578-86 - PMID: 16043658

Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice.

Moore KJ, Kunjathoor VV, Koehn SL, Manning JJ, Tseng AA, Silver JM, McKee M, Freeman MW
J Clin Invest. 2005;115(8):2192-201 - PMID: 16075060 - PMCID: PMC1180534

Nonparametric methods for microarray data based on exchangeability and borrowed power.

Lee ML, Whitmore GA, Björkbacka H, Freeman MW
J Biopharm Stat. 2005;15(5):783-97 - PMID: 16078385

Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.

Okuhira K, Fitzgerald ML, Sarracino DA, Manning JJ, Bell SA, Goss JL, Freeman MW
J Biol Chem. 2005;280(47):39653-64 - PMID: 16192269

Assembly of polymorphic genomes: algorithms and application to Ciona savignyi.

Vinson JP, Jaffe DB, O'Neill K, Karlsson EK, Stange-Thomann N, Anderson S, Mesirov JP, Satoh N, Satou Y, Nusbaum C, Birren B, Galagan JE, Lander ES
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Genome sequence, comparative analysis and haplotype structure of the domestic dog.

Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal M, Clamp M, Chang JL, Kulbokas EJ, Zody MC, Mauceli E, Xie X, Breen M, Wayne RK, Ostrander EA, Ponting CP, Galibert F, Smith DR, DeJong PJ, Kirkness E, Alvarez P, Biagi T, Brockman W, Butler J, Chin CW, Cook A, Cuff J, Daly MJ, DeCaprio D, Gnerre S, Grabherr M, Kellis M, Kleber M, Bardeleben C, Goodstadt L, Heger A, Hitte C, Kim L, Koepfli KP, Parker HG, Pollinger JP, Searle SM, Sutter NB, Thomas R, Webber C, Baldwin J, Abeb ...
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Functional genomic analysis of RNA interference in C. elegans.

Kim JK, Gabel HW, Kamath RS, Tewari M, Pasquinelli A, Rual JF, Kennedy S, Dybbs M, Bertin N, Kaplan JM, Vidal M, Ruvkun G
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Analysis of xbx genes in C. elegans.

Efimenko E, Bubb K, Mak HY, Holzman T, Leroux MR, Ruvkun G, Thomas JH, Swoboda P
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The tiny RNA world.

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Harvey Lect. 2005;99:1-21 - PMID: 15984549

A systematic RNAi screen for longevity genes in C. elegans.

Hamilton B, Dong Y, Shindo M, Liu W, Odell I, Ruvkun G, Lee SS
Genes Dev. 2005;19(13):1544-55 - PMID: 15998808 - PMCID: PMC1172061

Systematic analysis of genes required for synapse structure and function.

Sieburth D, Ch'ng Q, Dybbs M, Tavazoie M, Kennedy S, Wang D, Dupuy D, Rual JF, Hill DE, Vidal M, Ruvkun G, Kaplan JM
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Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants.

Wang D, Kennedy S, Conte D, Kim JK, Gabel HW, Kamath RS, Mello CC, Ruvkun G
Nature. 2005;436(7050):593-7 - PMID: 16049496

Regulation of Caenorhabditis elegans RNA interference by the daf-2 insulin stress and longevity signaling pathway.

Wang D, Ruvkun G
Cold Spring Harb Symp Quant Biol. 2005;69:429-31 - PMID: 16117677

Functional genomic analysis of C. elegans molting.

Frand AR, Russel S, Ruvkun G
PLoS Biol. 2005;3(10):e312 - PMID: 16122351 - PMCID: PMC1233573

Large-scale screens for cDNAs with in vivo activity.

Ting A, Lichtenthaler S, Xavier R, Na SY, Rabizadeh S, Holmes T, Seed B
Novartis Found Symp. 2005;267:219-29; discussion 229-30 - PMID: 15999809

Commensal flora: wolf in sheep's clothing.

Xavier R, Podolsky DK
Gastroenterology. 2005;128(4):1122-6 - PMID: 15825094

PDZ domains and the politics of polarity in lymphocytes.

Xavier R, Seed B
Immunity. 2005;22(6):655-6 - PMID: 15963778

Bioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells.

Lopez-Ilasaca MA, Bernabe-Ortiz JC, Na SY, Dzau VJ, Xavier RJ
FEBS Lett. 2005;579(3):648-54 - PMID: 15670823

GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells.

Barnich N, Hisamatsu T, Aguirre JE, Xavier R, Reinecker HC, Podolsky DK
J Biol Chem. 2005;280(19):19021-6 - PMID: 15753091

Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition.

Barnich N, Aguirre JE, Reinecker HC, Xavier R, Podolsky DK
J Cell Biol. 2005;170(1):21-6 - PMID: 15998797 - PMCID: PMC2171381

Sugar sensing and signalling networks in plants.

Rolland F, Sheen J
Biochem Soc Trans. 2005;33(Pt 1):269-71 - PMID: 15667323

Generalized rank tests for replicated microarray data.

Lee ML, Gray RJ, Björkbacka H, Freeman MW
Stat Appl Genet Mol Biol. 2005;4:Article3 - PMID: 16646848

Harvard Medical School Guide to Lowering your Cholesterol

MW Freeman and Christine Junge
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Technique for expanding the donor liver pool: heat shock preconditioning in a rat fatty liver model.

Mokuno Y, Berthiaume F, Tompkins RG, Balis UJ, Yarmush ML
Liver Transpl. 2004;10(2):264-72 - PMID: 14762865

Short-term enteral glutamine does not enhance protein accretion in burned children: a stable isotope study.

Sheridan RL, Prelack K, Yu YM, Lydon M, Petras L, Young VR, Tompkins RG
Surgery. 2004;135(6):671-8 - PMID: 15179374

Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication.

Déziel E, Lépine F, Milot S, He J, Mindrinos MN, Tompkins RG, Rahme LG
Proc Natl Acad Sci U S A. 2004;101(5):1339-44 - PMID: 14739337 - PMCID: PMC337054

Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue.

Carter EA, Burks D, Fischman AJ, White M, Tompkins RG
Int J Mol Med. 2004;14(4):653-8 - PMID: 15375597

Support of the metabolic response to burn injury.

Herndon DN, Tompkins RG
Lancet. 2004;363(9424):1895-902 - PMID: 15183630

Whole blood and leukocyte RNA isolation for gene expression analyses.

Feezor RJ, Baker HV, Mindrinos M, Hayden D, Tannahill CL, Brownstein BH, Fay A, MacMillan S, Laramie J, Xiao W, Moldawer LL, Cobb JP, Laudanski K, Miller-Graziano CL, Maier RV, Schoenfeld D, Davis RW, Tompkins RG,
Physiol Genomics. 2004;19(3):247-54 - PMID: 15548831

Development of a microfabricated cytometry platform for characterization and sorting of individual leukocytes.

Revzin A, Sekine K, Sin A, Tompkins RG, Toner M
Lab Chip. 2004;5(1):30-7 - PMID: 15616737

Continuous flow microfluidic device for rapid erythrocyte lysis.

Sethu P, Anahtar M, Moldawer LL, Tompkins RG, Toner M
Anal Chem. 2004;76(21):6247-53 - PMID: 15516115

Single-cell chemical lysis in picoliter-scale closed volumes using a microfabricated device.

Irimia D, Tompkins RG, Toner M
Anal Chem. 2004;76(20):6137-43 - PMID: 15481964

Effect of flow and surface conditions on human lymphocyte isolation using microfluidic chambers.

Murthy SK, Sin A, Tompkins RG, Toner M
Langmuir. 2004;20(26):11649-55 - PMID: 15595794

What's new in burns and metabolism.

Sheridan RL, Tompkins RG
J Am Coll Surg. 2004;198(2):243-63 - PMID: 14759783

Long-term function of cryopreserved rat hepatocytes in a coculture system.

Sugimachi K, Sosef MN, Baust JM, Fowler A, Tompkins RG, Toner M
Cell Transplant. 2004;13(2):187-95 - PMID: 15129765

Ultra-high-efficiency strong cation exchange LC/RPLC/MS/MS for high dynamic range characterization of the human plasma proteome.

Shen Y, Jacobs JM, Camp DG, Fang R, Moore RJ, Smith RD, Xiao W, Davis RW, Tompkins RG
Anal Chem. 2004;76(4):1134-44 - PMID: 14961748

The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response.

Mizuno T, Hisamoto N, Terada T, Kondo T, Adachi M, Nishida E, Kim DH, Ausubel FM, Matsumoto K
EMBO J. 2004;23(11):2226-34 - PMID: 15116070 - PMCID: PMC419906

VPEgamma exhibits a caspase-like activity that contributes to defense against pathogens.

Rojo E, Martín R, Carter C, Zouhar J, Pan S, Plotnikova J, Jin H, Paneque M, Sánchez-Serrano JJ, Baker B, Ausubel FM, Raikhel NV
Curr Biol. 2004;14(21):1897-906 - PMID: 15530390

Cytotoxicity of hydrogen peroxide produced by Enterococcus faecium.

Moy TI, Mylonakis E, Calderwood SB, Ausubel FM
Infect Immun. 2004;72(8):4512-20 - PMID: 15271910 - PMCID: PMC470665

Construction of an Enterococcus faecalis Tn917-mediated-gene-disruption library offers insight into Tn917 insertion patterns.

Garsin DA, Urbach J, Huguet-Tapia JC, Peters JE, Ausubel FM
J Bacteriol. 2004;186(21):7280-9 - PMID: 15489440 - PMCID: PMC523214

Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase.

Kim DH, Liberati NT, Mizuno T, Inoue H, Hisamoto N, Matsumoto K, Ausubel FM
Proc Natl Acad Sci U S A. 2004;101(30):10990-4 - PMID: 15256594 - PMCID: PMC503731

Contribution of gelatinase, serine protease, and fsr to the pathogenesis of Enterococcus faecalis endophthalmitis.

Engelbert M, Mylonakis E, Ausubel FM, Calderwood SB, Gilmore MS
Infect Immun. 2004;72(6):3628-33 - PMID: 15155673 - PMCID: PMC415677

Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response.

Apidianakis Y, Rahme LG, Heitman J, Ausubel FM, Calderwood SB, Mylonakis E
Eukaryot Cell. 2004;3(2):413-9 - PMID: 15075271 - PMCID: PMC387633

Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions.

Tenor JL, McCormick BA, Ausubel FM, Aballay A
Curr Biol. 2004;14(11):1018-24 - PMID: 15182677

Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals.

Mylonakis E, Idnurm A, Moreno R, El Khoury J, Rottman JB, Ausubel FM, Heitman J, Calderwood SB
Mol Microbiol. 2004;54(2):407-19 - PMID: 15469513

Evolutionary optimization of a nonbiological ATP binding protein for improved folding stability.

Chaput JC, Szostak JW
Chem Biol. 2004;11(6):865-74 - PMID: 15217619

Replicating vesicles as models of primitive cell growth and division.

Hanczyc MM, Szostak JW
Curr Opin Chem Biol. 2004;8(6):660-4 - PMID: 15556412

Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles.

Chen IA, Szostak JW
Proc Natl Acad Sci U S A. 2004;101(21):7965-70 - PMID: 15148394 - PMCID: PMC419540

The emergence of competition between model protocells.

Chen IA, Roberts RW, Szostak JW
Science. 2004;305(5689):1474-6 - PMID: 15353806 - PMCID: PMC4484590

A kinetic study of the growth of fatty acid vesicles.

Chen IA, Szostak JW
Biophys J. 2004;87(2):988-98 - PMID: 15298905 - PMCID: PMC1304506

Informational complexity and functional activity of RNA structures.

Carothers JM, Oestreich SC, Davis JH, Szostak JW
J Am Chem Soc. 2004;126(16):5130-7 - PMID: 15099096 - PMCID: PMC5042360

A small aptamer with strong and specific recognition of the triphosphate of ATP.

Sazani PL, Larralde R, Szostak JW
J Am Chem Soc. 2004;126(27):8370-1 - PMID: 15237981 - PMCID: PMC4983724

High-throughput beta-galactosidase assay for bacterial cell-based reporter systems.

Thibodeau SA, Fang R, Joung JK
Biotechniques. 2004;36(3):410-5 - PMID: 15038156

Allosteric inhibition of zinc-finger binding in the major groove of DNA by minor-groove binding ligands.

Nguyen-Hackley DH, Ramm E, Taylor CM, Joung JK, Dervan PB, Pabo CO
Biochemistry. 2004;43(13):3880-90 - PMID: 15049695

The knockout mouse project.

Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH, Lloyd KC, Magnuson T, Moore MW, Nagy A, Pollock JD, Roses AD, Sands AT, Seed B, Skarnes WC, Snoddy J, Soriano P, Stewart DJ, Stewart F, Stillman B, Varmus H, Varticovski L, Verma IM, Vogt TF, von Melchner H, Witkowski J, Woychik RP, Wurst W, Yancopoulos GD, Young SG, Zambrowicz B
Nat Genet. 2004;36(9):921-4 - PMID: 15340423 - PMCID: PMC2716027

Differential transplantability of tumor-associated stromal cells.

Duda DG, Fukumura D, Munn LL, Booth MF, Brown EB, Huang P, Seed B, Jain RK
Cancer Res. 2004;64(17):5920-4 - PMID: 15342367

Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1.

Chroni A, Liu T, Fitzgerald ML, Freeman MW, Zannis VI
Biochemistry. 2004;43(7):2126-39 - PMID: 14967052

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways.

Björkbacka H, Kunjathoor VV, Moore KJ, Koehn S, Ordija CM, Lee MA, Means T, Halmen K, Luster AD, Golenbock DT, Freeman MW
Nat Med. 2004;10(4):416-21 - PMID: 15034566

ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities.

Fitzgerald ML, Okuhira K, Short GF, Manning JJ, Bell SA, Freeman MW
J Biol Chem. 2004;279(46):48477-85 - PMID: 15347662

The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.

Björkbacka H, Fitzgerald KA, Huet F, Li X, Gregory JA, Lee MA, Ordija CM, Dowley NE, Golenbock DT, Freeman MW
Physiol Genomics. 2004;19(3):319-30 - PMID: 15367722

Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.

Kim WS, Fitzgerald ML, Kang K, Okuhira K, Bell SA, Manning JJ, Koehn SL, Lu N, Moore KJ, Freeman MW
J Biol Chem. 2004;280(5):3989-95 - PMID: 15550377

Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis.

Ricci R, Sumara G, Sumara I, Rozenberg I, Kurrer M, Akhmedov A, Hersberger M, Eriksson U, Eberli FR, Becher B, Borén J, Chen M, Cybulsky MI, Moore KJ, Freeman MW, Wagner EF, Matter CM, Lüscher TF
Science. 2004;306(5701):1558-61 - PMID: 15567863

The complete genome and proteome of Mycoplasma mobile.

Jaffe JD, Stange-Thomann N, Smith C, DeCaprio D, Fisher S, Butler J, Calvo S, Elkins T, FitzGerald MG, Hafez N, Kodira CD, Major J, Wang S, Wilkinson J, Nicol R, Nusbaum C, Birren B, Berg HC, Church GM
Genome Res. 2004;14(8):1447-61 - PMID: 15289470 - PMCID: PMC509254

Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype.

Jaillon O, Aury JM, Brunet F, Petit JL, Stange-Thomann N, Mauceli E, Bouneau L, Fischer C, Ozouf-Costaz C, Bernot A, Nicaud S, Jaffe D, Fisher S, Lutfalla G, Dossat C, Segurens B, Dasilva C, Salanoubat M, Levy M, Boudet N, Castellano S, Anthouard V, Jubin C, Castelli V, Katinka M, Vacherie B, Biémont C, Skalli Z, Cattolico L, Poulain J, De Berardinis V, Cruaud C, Duprat S, Brottier P, Coutanceau JP, Gouzy J, Parra G, Lardier G, Chapple C, McKernan KJ, McEwan P, Bosak S, Kellis M, Volff JN, G ...
Nature. 2004;431(7011):946-57 - PMID: 15496914

A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.

Kennedy S, Wang D, Ruvkun G
Nature. 2004;427(6975):645-9 - PMID: 14961122

Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network.

Tewari M, Hu PJ, Ahn JS, Ayivi-Guedehoussou N, Vidalain PO, Li S, Milstein S, Armstrong CM, Boxem M, Butler MD, Busiguina S, Rual JF, Ibarrola N, Chaklos ST, Bertin N, Vaglio P, Edgley ML, King KV, Albert PS, Vandenhaute J, Pandey A, Riddle DL, Ruvkun G, Vidal M
Mol Cell. 2004;13(4):469-82 - PMID: 14992718

The 20 years it took to recognize the importance of tiny RNAs.

Ruvkun G, Wightman B, Ha I
Cell. 2004;116(2 Suppl):S93-6, 2 p following S96 - PMID: 15055593

Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450.

Mak HY, Ruvkun G
Development. 2004;131(8):1777-86 - PMID: 15084462

MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression.

Mansfield JH, Harfe BD, Nissen R, Obenauer J, Srineel J, Chaudhuri A, Farzan-Kashani R, Zuker M, Pasquinelli AE, Ruvkun G, Sharp PA, Tabin CJ, McManus MT
Nat Genet. 2004;36(10):1079-83 - PMID: 15361871

Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response.

Liberati NT, Fitzgerald KA, Kim DH, Feinbaum R, Golenbock DT, Ausubel FM
Proc Natl Acad Sci U S A. 2004;101(17):6593-8 - PMID: 15123841 - PMCID: PMC404090

Paradoxical roles of different nitric oxide synthase isoforms in colonic injury.

Beck PL, Xavier R, Wong J, Ezedi I, Mashimo H, Mizoguchi A, Mizoguchi E, Bhan AK, Podolsky DK
Am J Physiol Gastrointest Liver Physiol. 2004;286(1):G137-47 - PMID: 14665440

Chemotherapy- and radiotherapy-induced intestinal damage is regulated by intestinal trefoil factor.

Beck PL, Wong JF, Li Y, Swaminathan S, Xavier RJ, Devaney KL, Podolsky DK
Gastroenterology. 2004;126(3):796-808 - PMID: 14988834

The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death.

Rabizadeh S, Xavier RJ, Ishiguro K, Bernabeortiz J, Lopez-Ilasaca M, Khokhlatchev A, Mollahan P, Pfeifer GP, Avruch J, Seed B
J Biol Chem. 2004;279(28):29247-54 - PMID: 15075335

Discs large (Dlg1) complexes in lymphocyte activation.

Xavier R, Rabizadeh S, Ishiguro K, Andre N, Ortiz JB, Wachtel H, Morris DG, Lopez-Ilasaca M, Shaw AC, Swat W, Seed B
J Cell Biol. 2004;166(2):173-8 - PMID: 15263016 - PMCID: PMC2172307

Wave2 activates serum response element via its VCA region and functions downstream of Rac.

Ishiguro K, Cao Z, Ilasca ML, Ando T, Xavier R
Exp Cell Res. 2004;301(2):331-7 - PMID: 15530867

Expression of an active tobacco mitogen-activated protein kinase kinase kinase enhances freezing tolerance in transgenic maize.

Shou H, Bordallo P, Fan JB, Yeakley JM, Bibikova M, Sheen J, Wang K
Proc Natl Acad Sci U S A. 2004;101(9):3298-303 - PMID: 14960727 - PMCID: PMC365784

Central role of interleukin-6 in burn induced stimulation of hepatic amino acid transport.

Pawlik TM, Carter EA, Bode BP, Fischman AJ, Tompkins RG
Int J Mol Med. 2003;12(4):541-8 - PMID: 12964032

The Drosophila melanogaster toll pathway participates in resistance to infection by the gram-negative human pathogen Pseudomonas aeruginosa.

Lau GW, Goumnerov BC, Walendziewicz CL, Hewitson J, Xiao W, Mahajan-Miklos S, Tompkins RG, Perkins LA, Rahme LG
Infect Immun. 2003;71(7):4059-66 - PMID: 12819096 - PMCID: PMC162001

Efficacy of an extracorporeal flat-plate bioartificial liver in treating fulminant hepatic failure.

Shito M, Tilles AW, Tompkins RG, Yarmush ML, Toner M
J Surg Res. 2003;111(1):53-62 - PMID: 12842448

Bioengineering of liver assist devices.

Tilles AW, Berthiaume F, Yarmush ML, Tompkins RG, Toner M
J Hepatobiliary Pancreat Surg. 2003;9(6):686-96 - PMID: 12658402

Metabolic fate of extrahepatic arginine in liver after burn injury.

Chen CL, Fei Z, Carter EA, Lu XM, Hu RH, Young VR, Tompkins RG, Yu YM
Metabolism. 2003;52(10):1232-9 - PMID: 14564672

Five components of the ethylene-response pathway identified in a screen for weak ethylene-insensitive mutants in Arabidopsis.

Alonso JM, Stepanova AN, Solano R, Wisman E, Ferrari S, Ausubel FM, Ecker JR
Proc Natl Acad Sci U S A. 2003;100(5):2992-7 - PMID: 12606727 - PMCID: PMC151454

The art of serendipity: killing of Caenorhabditis elegans by human pathogens as a model of bacterial and fungal pathogenesis.

Mylonakis E, Ausubel FM, Tang RJ, Calderwood SB
Expert Rev Anti Infect Ther. 2003;1(1):167-73 - PMID: 15482109

Use of the Galleria mellonella caterpillar as a model host to study the role of the type III secretion system in Pseudomonas aeruginosa pathogenesis.

Miyata S, Casey M, Frank DW, Ausubel FM, Drenkard E
Infect Immun. 2003;71(5):2404-13 - PMID: 12704110 - PMCID: PMC153283

Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis.

Sifri CD, Begun J, Ausubel FM, Calderwood SB
Infect Immun. 2003;71(4):2208-17 - PMID: 12654843 - PMCID: PMC152095

Tandemly duplicated Arabidopsis genes that encode polygalacturonase-inhibiting proteins are regulated coordinately by different signal transduction pathways in response to fungal infection.

Ferrari S, Vairo D, Ausubel FM, Cervone F, De Lorenzo G
Plant Cell. 2003;15(1):93-106 - PMID: 12509524 - PMCID: PMC143454

Hypersusceptibility of cystic fibrosis mice to chronic Pseudomonas aeruginosa oropharyngeal colonization and lung infection.

Coleman FT, Mueschenborn S, Meluleni G, Ray C, Carey VJ, Vargas SO, Cannon CL, Ausubel FM, Pier GB
Proc Natl Acad Sci U S A. 2003;100(4):1949-54 - PMID: 12578988 - PMCID: PMC149939

Functional information: Molecular messages.

Szostak JW
Nature. 2003;423(6941):689 - PMID: 12802312

Evolution of aptamers with a new specificity and new secondary structures from an ATP aptamer.

Huang Z, Szostak JW
RNA. 2003;9(12):1456-63 - PMID: 14624002 - PMCID: PMC1370500

DNA polymerase-mediated DNA synthesis on a TNA template.

Chaput JC, Ichida JK, Szostak JW
J Am Chem Soc. 2003;125(4):856-7 - PMID: 12537469

A novel, modification-dependent ATP-binding aptamer selected from an RNA library incorporating a cationic functionality.

Vaish NK, Larralde R, Fraley AW, Szostak JW, McLaughlin LW
Biochemistry. 2003;42(29):8842-51 - PMID: 12873145

Selective labeling and detection of specific RNAs in an RNA mixture.

Huang Z, Szostak JW
Anal Biochem. 2003;315(1):129-33 - PMID: 12672421

Experimental models of primitive cellular compartments: encapsulation, growth, and division.

Hanczyc MM, Fujikawa SM, Szostak JW
Science. 2003;302(5645):618-22 - PMID: 14576428 - PMCID: PMC4484575

TNA synthesis by DNA polymerases.

Chaput JC, Szostak JW
J Am Chem Soc. 2003;125(31):9274-5 - PMID: 12889939

Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion.

Lucas M, Stuart LM, Savill J, Lacy-Hulbert A
J Immunol. 2003;171(5):2610-5 - PMID: 12928413

Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection.

Hurt JA, Thibodeau SA, Hirsh AS, Pabo CO, Joung JK
Proc Natl Acad Sci U S A. 2003;100(21):12271-6 - PMID: 14527993 - PMCID: PMC218748

Efficient and stable retroviral transfection of ovine endothelial cells with green fluorescent protein for cardiovascular tissue engineering.

Afting M, Stock UA, Nasseri B, Pomerantseva I, Seed B, Vacanti JP
Tissue Eng. 2003;9(1):137-41 - PMID: 12625962

Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes.

Yang Y, Seed B
Nat Biotechnol. 2003;21(4):447-51 - PMID: 12627171

Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKK alpha-dependent noncanonical NF-kappaB activation.

Luftig M, Yasui T, Soni V, Kang MS, Jacobson N, Cahir-McFarland E, Seed B, Kieff E
Proc Natl Acad Sci U S A. 2003;101(1):141-6 - PMID: 14691250 - PMCID: PMC314152

Selection of oligonucleotide probes for protein coding sequences.

Wang X, Seed B
Bioinformatics. 2003;19(7):796-802 - PMID: 12724288

Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation.

Brown E, McKee T, diTomaso E, Pluen A, Seed B, Boucher Y, Jain RK
Nat Med. 2003;9(6):796-800 - PMID: 12754503

A PCR primer bank for quantitative gene expression analysis.

Wang X, Seed B
Nucleic Acids Res. 2003;31(24):e154 - PMID: 14654707 - PMCID: PMC291882

The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1.

Lichtenthaler SF, Dominguez DI, Westmeyer GG, Reiss K, Haass C, Saftig P, De Strooper B, Seed B
J Biol Chem. 2003;278(49):48713-9 - PMID: 14507929

eLiXiRs for restraining inflammation.

Freeman MW, Moore KJ
Nat Med. 2003;9(2):168-9 - PMID: 12563335

CD36 mediates the innate host response to beta-amyloid.

El Khoury JB, Moore KJ, Means TK, Leung J, Terada K, Toft M, Freeman MW, Luster AD
J Exp Med. 2003;197(12):1657-66 - PMID: 12796468 - PMCID: PMC2193948

Activation of signaling pathways by putative scavenger receptor class A (SR-A) ligands requires CD14 but not SR-A.

Kim WS, Ordija CM, Freeman MW
Biochem Biophys Res Commun. 2003;310(2):542-9 - PMID: 14521944

ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux.

Fitzgerald ML, Morris AL, Chroni A, Mendez AJ, Zannis VI, Freeman MW
J Lipid Res. 2003;45(2):287-94 - PMID: 14617740

Pathogen discovery from human tissue by sequence-based computational subtraction.

Xu Y, Stange-Thomann N, Weber G, Bo R, Dodge S, David RG, Foley K, Beheshti J, Harris NL, Birren B, Lander ES, Meyerson M
Genomics. 2003;81(3):329-35 - PMID: 12659816

The genome sequence of the filamentous fungus Neurospora crassa.

Galagan JE, Calvo SE, Borkovich KA, Selker EU, Read ND, Jaffe D, FitzHugh W, Ma LJ, Smirnov S, Purcell S, Rehman B, Elkins T, Engels R, Wang S, Nielsen CB, Butler J, Endrizzi M, Qui D, Ianakiev P, Bell-Pedersen D, Nelson MA, Werner-Washburne M, Selitrennikoff CP, Kinsey JA, Braun EL, Zelter A, Schulte U, Kothe GO, Jedd G, Mewes W, Staben C, Marcotte E, Greenberg D, Roy A, Foley K, Naylor J, Stange-Thomann N, Barrett R, Gnerre S, Kamal M, Kamvysselis M, Mauceli E, Bielke C, Rudd S, Frishman D ...
Nature. 2003;422(6934):859-68 - PMID: 12712197

Anteroposterior patterning in hemichordates and the origins of the chordate nervous system.

Lowe CJ, Wu M, Salic A, Evans L, Lander E, Stange-Thomann N, Gruber CE, Gerhart J, Kirschner M
Cell. 2003;113(7):853-65 - PMID: 12837244

Comparative genomic analysis reveals independent expansion of a lineage-specific gene family in vertebrates: the class II cytokine receptors and their ligands in mammals and fish.

Lutfalla G, Roest Crollius H, Stange-Thomann N, Jaillon O, Mogensen K, Monneron D
BMC Genomics. 2003;4(1):29 - PMID: 12869211 - PMCID: PMC179897

Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes.

Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, Ahringer J, Ruvkun G
Nature. 2003;421(6920):268-72 - PMID: 12529643

A uniform system for microRNA annotation.

Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M, Matzke M, Ruvkun G, Tuschl T
RNA. 2003;9(3):277-9 - PMID: 12592000 - PMCID: PMC1370393

daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway.

Li W, Kennedy SG, Ruvkun G
Genes Dev. 2003;17(7):844-58 - PMID: 12654727 - PMCID: PMC196030

DAF-16 target genes that control C. elegans life-span and metabolism.

Lee SS, Kennedy S, Tolonen AC, Ruvkun G
Science. 2003;300(5619):644-7 - PMID: 12690206

Computational and experimental identification of C. elegans microRNAs.

Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J
Mol Cell. 2003;11(5):1253-63 - PMID: 12769849

The Caenorhabditis elegans ems class homeobox gene ceh-2 is required for M3 pharynx motoneuron function.

Aspöck G, Ruvkun G, Bürglin TR
Development. 2003;130(15):3369-78 - PMID: 12810585

Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis.

Bashirullah A, Pasquinelli AE, Kiger AA, Perrimon N, Ruvkun G, Thummel CS
Dev Biol. 2003;259(1):1-8 - PMID: 12812783

Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens.

Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM
Science. 2003;300(5627):1921 - PMID: 12817143

Expression of the 22 nucleotide let-7 heterochronic RNA throughout the Metazoa: a role in life history evolution?

Pasquinelli AE, McCoy A, Jiménez E, Saló E, Ruvkun G, Martindale MQ, Baguñà J
Evol Dev. 2003;5(4):372-8 - PMID: 12823453

Activity of the Caenorhabditis elegans UNC-86 POU transcription factor modulates olfactory sensitivity.

Sze JY, Ruvkun G
Proc Natl Acad Sci U S A. 2003;100(16):9560-5 - PMID: 12883006 - PMCID: PMC170957

Functional tests of enhancer conservation between distantly related species.

Ruvinsky I, Ruvkun G
Development. 2003;130(21):5133-42 - PMID: 12944426

Identification of many microRNAs that copurify with polyribosomes in mammalian neurons.

Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G
Proc Natl Acad Sci U S A. 2003;101(1):360-5 - PMID: 14691248 - PMCID: PMC314190

Unraveling the secrets of the cell.

Komaroff AL, Ruvkun G
Newsweek. 2003;142(23):96 - PMID: 14712576

Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway.

Aballay A, Drenkard E, Hilbun LR, Ausubel FM
Curr Biol. 2003;13(1):47-52 - PMID: 12526744

Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens.

Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM
Science. 2003;300(5627):1921 - PMID: 12817143

Arabidopsis local resistance to Botrytis cinerea involves salicylic acid and camalexin and requires EDS4 and PAD2, but not SID2, EDS5 or PAD4.

Ferrari S, Plotnikova JM, De Lorenzo G, Ausubel FM
Plant J. 2003;35(2):193-205 - PMID: 12848825

Transforming growth factor-beta mediates intestinal healing and susceptibility to injury in vitro and in vivo through epithelial cells.

Beck PL, Rosenberg IM, Xavier RJ, Koh T, Wong JF, Podolsky DK
Am J Pathol. 2003;162(2):597-608 - PMID: 12547717 - PMCID: PMC1851153

Essential role for Vav1 in activation, but not development, of gammadelta T cells.

Swat W, Xavier R, Mizoguchi A, Mizoguchi E, Fredericks J, Fujikawa K, Bhan AK, Alt FW
Int Immunol. 2003;15(2):215-21 - PMID: 12578851

Colonic epithelial functional phenotype varies with type and phase of experimental colitis.

Mizoguchi E, Xavier RJ, Reinecker HC, Uchino H, Bhan AK, Podolsky DK, Mizoguchi A
Gastroenterology. 2003;125(1):148-61 - PMID: 12851880

Homer-3 regulates activation of serum response element in T cells via its EVH1 domain.

Ishiguro K, Xavier R
Blood. 2003;103(6):2248-56 - PMID: 14645007

Sugar and hormone connections.

León P, Sheen J
Trends Plant Sci. 2003;8(3):110-6 - PMID: 12663220

Role of the Arabidopsis glucose sensor HXK1 in nutrient, light, and hormonal signaling.

Moore B, Zhou L, Rolland F, Hall Q, Cheng WH, Liu YX, Hwang I, Jones T, Sheen J
Science. 2003;300(5617):332-6 - PMID: 12690200

Differential regulation of EIN3 stability by glucose and ethylene signalling in plants.

Yanagisawa S, Yoo SD, Sheen J
Nature. 2003;425(6957):521-5 - PMID: 14523448

An improved strategy for constructing "designer" Cys2His2 zinc finger proteins.

Thibodeau SA, Joung JK
Discov Med. 2003;3(19):32-5 - PMID: 20705034

Use of Integra artificial skin is associated with decreased length of stay for severely injured adult burn survivors.

Ryan CM, Schoenfeld DA, Malloy M, Schulz JT, Sheridan RL, Tompkins RG
J Burn Care Rehabil. 2002;23(5):311-7 - PMID: 12352131

Effectiveness of bacteria-controlled nursing units in preventing cross-colonization with resistant bacteria in severely burned children.

Weber JM, Sheridan RL, Schulz JT, Tompkins RG, Ryan CM
Infect Control Hosp Epidemiol. 2002;23(9):549-51 - PMID: 12269456

Plasma L-5-oxoproline kinetics and whole blood glutathione synthesis rates in severely burned adult humans.

Yu YM, Ryan CM, Fei ZW, Lu XM, Castillo L, Schultz JT, Tompkins RG, Young VR
Am J Physiol Endocrinol Metab. 2002;282(2):E247-58 - PMID: 11788355

Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance.

Sugita H, Kaneki M, Tokunaga E, Sugita M, Koike C, Yasuhara S, Tompkins RG, Martyn JA
Am J Physiol Endocrinol Metab. 2002;282(2):E386-94 - PMID: 11788371

Mapping of local renal blood flow with PET and H(2)(15)O.

Alpert NM, Rabito CA, Correia DJ, Babich JW, Littman BH, Tompkins RG, Rubin NT, Rubin RH, Fischman AJ
J Nucl Med. 2002;43(4):470-5 - PMID: 11937589

Regional measurement of canine skeletal muscle blood flow by positron emission tomography with H2(15)O.

Fischman AJ, Hsu H, Carter EA, Yu YM, Tompkins RG, Guerrero JL, Young VR, Alpert NM
J Appl Physiol. 2002;92(4):1709-16 - PMID: 11896041

Long-term consequences of toxic epidermal necrolysis in children.

Sheridan RL, Schulz JT, Ryan CM, Schnitzer JJ, Lawlor D, Driscoll DN, Donelan MB, Tompkins RG
Pediatrics. 2002;109(1):74-8 - PMID: 11773544

In vivo rabbit hindquarter model for assessment of regional burn hypermetabolism.

Xu J, Fei Z, Yu YM, Xu W, Rhodes A, Tompkins RG, Schulz JT
J Appl Physiol. 2002;94(1):135-40 - PMID: 12391055

Identification of virulence genes in a pathogenic strain of Pseudomonas aeruginosa by representational difference analysis.

Choi JY, Sifri CD, Goumnerov BC, Rahme LG, Ausubel FM, Calderwood SB
J Bacteriol. 2002;184(4):952-61 - PMID: 11807055 - PMCID: PMC134824

Caenorhabditis elegans as a host for the study of host-pathogen interactions.

Aballay A, Ausubel FM
Curr Opin Microbiol. 2002;5(1):97-101 - PMID: 11834377

Strains of Escherichia coli O157:H7 differ primarily by insertions or deletions, not single-nucleotide polymorphisms.

Kudva IT, Evans PS, Perna NT, Barrett TJ, Ausubel FM, Blattner FR, Calderwood SB
J Bacteriol. 2002;184(7):1873-9 - PMID: 11889093 - PMCID: PMC134921

Virulence effect of Enterococcus faecalis protease genes and the quorum-sensing locus fsr in Caenorhabditis elegans and mice.

Sifri CD, Mylonakis E, Singh KV, Qin X, Garsin DA, Murray BE, Ausubel FM, Calderwood SB
Infect Immun. 2002;70(10):5647-50 - PMID: 12228293 - PMCID: PMC128331

Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis.

Mylonakis E, Ausubel FM, Perfect JR, Heitman J, Calderwood SB
Proc Natl Acad Sci U S A. 2002;99(24):15675-80 - PMID: 12438649 - PMCID: PMC137775

Polymorphic amplified typing sequences provide a novel approach to Escherichia coli O157:H7 strain typing.

Kudva IT, Evans PS, Perna NT, Barrett TJ, DeCastro GJ, Ausubel FM, Blattner FR, Calderwood SB
J Clin Microbiol. 2002;40(4):1152-9 - PMID: 11923324 - PMCID: PMC140341

Signals involved in Arabidopsis resistance to Trichoplusia ni caterpillars induced by virulent and avirulent strains of the phytopathogen Pseudomonas syringae.

Cui J, Jander G, Racki LR, Kim PD, Pierce NE, Ausubel FM
Plant Physiol. 2002;129(2):551-64 - PMID: 12068100 - PMCID: PMC161673

The Enterococcus faecalis fsrB gene, a key component of the fsr quorum-sensing system, is associated with virulence in the rabbit endophthalmitis model.

Mylonakis E, Engelbert M, Qin X, Sifri CD, Murray BE, Ausubel FM, Gilmore MS, Calderwood SB
Infect Immun. 2002;70(8):4678-81 - PMID: 12117982 - PMCID: PMC128160

Molecular biology: RNA gets a grip on translation.

Szostak JW
Nature. 2002;419(6910):890-1 - PMID: 12410294

Identification of epitope-like consensus motifs using mRNA display.

Baggio R, Burgstaller P, Hale SP, Putney AR, Lane M, Lipovsek D, Wright MC, Roberts RW, Liu R, Szostak JW, Wagner RW
J Mol Recognit. 2002;15(3):126-34 - PMID: 12203838

Isolation of high-affinity GTP aptamers from partially structured RNA libraries.

Davis JH, Szostak JW
Proc Natl Acad Sci U S A. 2002;99(18):11616-21 - PMID: 12185247 - PMCID: PMC129318

Inhibitory effects of apoptotic cell ingestion upon endotoxin-driven myeloid dendritic cell maturation.

Stuart LM, Lucas M, Simpson C, Lamb J, Savill J, Lacy-Hulbert A
J Immunol. 2002;168(4):1627-35 - PMID: 11823490

Identifying and modifying protein-DNA and protein-protein interactions using a bacterial two-hybrid selection system.

Joung JK
J Cell Biochem Suppl. 2002;Suppl 37:53-7 - PMID: 11842428

Ductal lavage and the clinical management of women at high risk for breast carcinoma: a commentary.

O'Shaughnessy JA, Ljung BM, Dooley WC, Chang J, Kuerer HM, Hung DT, Grant MD, Khan SA, Phillips RF, Duvall K, Euhus DM, King BL, Anderson BO, Troyan SL, Kim J, Veronesi U, Cazzaniga M
Cancer. 2002;94(2):292-8 - PMID: 11900214

The Treatment of Dyslipidemia: LDL Reduction and Beyond

MW Freeman
In Endocrinology Rounds. 2002;1, Issue 8:ePub

C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway.

Rosen ED, Hsu CH, Wang X, Sakai S, Freeman MW, Gonzalez FJ, Spiegelman BM
Genes Dev. 2002;16(1):22-6 - PMID: 11782441 - PMCID: PMC155311

Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home.

Fitzgerald ML, Moore KJ, Freeman MW
J Mol Med (Berl). 2002;80(5):271-81 - PMID: 12021839

Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I.

Fitzgerald ML, Morris AL, Rhee JS, Andersson LP, Mendez AJ, Freeman MW
J Biol Chem. 2002;277(36):33178-87 - PMID: 12084722

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

Moore KJ, El Khoury J, Medeiros LA, Terada K, Geula C, Luster AD, Freeman MW
J Biol Chem. 2002;277(49):47373-9 - PMID: 12239221

Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways.

Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V, Akira S, Kasper DL, Golenbock DT
J Immunol. 2002;169(7):3970-7 - PMID: 12244198

Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice.

Yang KK, Dorner BG, Merkel U, Ryffel B, Schütt C, Golenbock D, Freeman MW, Jack RS
J Immunol. 2002;169(8):4475-80 - PMID: 12370383

Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages.

Kunjathoor VV, Febbraio M, Podrez EA, Moore KJ, Andersson L, Koehn S, Rhee JS, Silverstein R, Hoff HF, Freeman MW
J Biol Chem. 2002;277(51):49982-8 - PMID: 12376530

The genome of M. acetivorans reveals extensive metabolic and physiological diversity.

Galagan JE, Nusbaum C, Roy A, Endrizzi MG, Macdonald P, FitzHugh W, Calvo S, Engels R, Smirnov S, Atnoor D, Brown A, Allen N, Naylor J, Stange-Thomann N, DeArellano K, Johnson R, Linton L, McEwan P, McKernan K, Talamas J, Tirrell A, Ye W, Zimmer A, Barber RD, Cann I, Graham DE, Grahame DA, Guss AM, Hedderich R, Ingram-Smith C, Kuettner HC, Krzycki JA, Leigh JA, Li W, Liu J, Mukhopadhyay B, Reeve JN, Smith K, Springer TA, Umayam LA, White O, White RH, Conway de Macario E, Ferry JG, Jarrell KF ...
Genome Res. 2002;12(4):532-42 - PMID: 11932238 - PMCID: PMC187521

Initial sequencing and comparative analysis of the mouse genome.

Mouse Genome Sequencing Consortium, Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough R, Alexandersson M, An P, Antonarakis SE, Attwood J, Baertsch R, Bailey J, Barlow K, Beck S, Berry E, Birren B, Bloom T, Bork P, Botcherby M, Bray N, Brent MR, Brown DG, Brown SD, Bult C, Burton J, Butler J, Campbell RD, Carninci P, Cawley S, Chiaromonte F, Chinwalla AT, Church DM, Clamp M, Clee C, Collins FS, Cook LL, Copley RR, Coulson A, Couronne O, Cuff J, Curw ...
Nature. 2002;420(6915):520-62 - PMID: 12466850

Longevity: don't hold your breath.

Lee SS, Ruvkun G
Nature. 2002;418(6895):287-8 - PMID: 12124610

The C. elegans POU-domain transcription factor UNC-86 regulates the tph-1 tryptophan hydroxylase gene and neurite outgrowth in specific serotonergic neurons.

Sze JY, Zhang S, Li J, Ruvkun G
Development. 2002;129(16):3901-11 - PMID: 12135927

Control of developmental timing by micrornas and their targets.

Pasquinelli AE, Ruvkun G
Annu Rev Cell Dev Biol. 2002;18:495-513 - PMID: 12142272

Insulin receptor substrate and p55 orthologous adaptor proteins function in the Caenorhabditis elegans daf-2/insulin-like signaling pathway.

Wolkow CA, Muñoz MJ, Riddle DL, Ruvkun G
J Biol Chem. 2002;277(51):49591-7 - PMID: 12393910

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity.

Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J, Ruvkun G
Nat Genet. 2002;33(1):40-8 - PMID: 12447374

Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation.

Drenkard E, Ausubel FM
Nature. 2002;416(6882):740-3 - PMID: 11961556

A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity.

Kim DH, Feinbaum R, Alloing G, Emerson FE, Garsin DA, Inoue H, Tanaka-Hino M, Hisamoto N, Matsumoto K, Tan MW, Ausubel FM
Science. 2002;297(5581):623-6 - PMID: 12142542

Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice.

Mizoguchi E, Mizoguchi A, Takedatsu H, Cario E, de Jong YP, Ooi CJ, Xavier RJ, Terhorst C, Podolsky DK, Bhan AK
Gastroenterology. 2002;122(1):134-44 - PMID: 11781288

Identification of a novel Ras-regulated proapoptotic pathway.

Khokhlatchev A, Rabizadeh S, Xavier R, Nedwidek M, Chen T, Zhang XF, Seed B, Avruch J
Curr Biol. 2002;12(4):253-65 - PMID: 11864565

Decreased bone density in splenectomized Gaucher patients receiving enzyme replacement therapy.

Schiffmann R, Mankin H, Dambrosia JM, Xavier RJ, Kreps C, Hill SC, Barton NW, Rosenthal DI
Blood Cells Mol Dis. 2002;28(2):288-96 - PMID: 12064924

MAP kinase signalling cascade in Arabidopsis innate immunity.

Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J
Nature. 2002;415(6875):977-83 - PMID: 11875555

Phosphorelay and transcription control in cytokinin signal transduction.

Sheen J
Science. 2002;296(5573):1650-2 - PMID: 12040183

Sugar sensing and signaling in plants.

Rolland F, Moore B, Sheen J
Plant Cell. 2002;14 Suppl:S185-205 - PMID: 12045277 - PMCID: PMC151255

Calcium signaling through protein kinases. The Arabidopsis calcium-dependent protein kinase gene family.

Cheng SH, Willmann MR, Chen HC, Sheen J
Plant Physiol. 2002;129(2):469-85 - PMID: 12068094 - PMCID: PMC1540234

Two-component signal transduction pathways in Arabidopsis.

Hwang I, Chen HC, Sheen J
Plant Physiol. 2002;129(2):500-15 - PMID: 12068096 - PMCID: PMC161668

A unique short-chain dehydrogenase/reductase in Arabidopsis glucose signaling and abscisic acid biosynthesis and functions.

Cheng WH, Endo A, Zhou L, Penney J, Chen HC, Arroyo A, Leon P, Nambara E, Asami T, Seo M, Koshiba T, Sheen J
Plant Cell. 2002;14(11):2723-43 - PMID: 12417697 - PMCID: PMC152723

L-histidine decarboxylase decreases its own transcription through downregulation of ERK activity.

Colucci R, Fleming JV, Xavier R, Wang TC
Am J Physiol Gastrointest Liver Physiol. 2001;281(4):G1081-91 - PMID: 11557529

Hepatitis C virus replication is directly inhibited by IFN-alpha in a full-length binary expression system.

Chung RT, He W, Saquib A, Contreras AM, Xavier RJ, Chawla A, Wang TC, Schmidt EV
Proc Natl Acad Sci U S A. 2001;98(17):9847-52 - PMID: 11493707 - PMCID: PMC55541

Gaucher disease. New approaches to an ancient disease.

Mankin HJ, Rosenthal DI, Xavier R
J Bone Joint Surg Am. 2001;83-A(5):748-62 - PMID: 11379747

TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome.

Merscher S, Funke B, Epstein JA, Heyer J, Puech A, Lu MM, Xavier RJ, Demay MB, Russell RG, Factor S, Tokooya K, Jore BS, Lopez M, Pandita RK, Lia M, Carrion D, Xu H, Schorle H, Kobler JB, Scambler P, Wynshaw-Boris A, Skoultchi AI, Morrow BE, Kucherlapati R
Cell. 2001;104(4):619-29 - PMID: 11239417

The American Burn Association in the New Millennium.

Tompkins RG
J Burn Care Rehabil. 2001;22(6):369-374 - PMID: 11773770

Initial experience with a composite autologous skin substitute.

Sheridan RL, Morgan JR, Cusick JL, Petras LM, Lydon MM, Tompkins RG
Burns. 2001;27(5):421-4 - PMID: 11451592

A fulminant hepatic failure model in the rat: involvement of interleukin-1beta and tumor necrosis factor-alpha.

Shito M, Balis UJ, Tompkins RG, Yarmush ML, Toner M
Dig Dis Sci. 2001;46(8):1700-8 - PMID: 11508670

Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal.

Yu YM, Ryan CM, Castillo L, Lu XM, Beaumier L, Tompkins RG, Young VR
Am J Physiol Endocrinol Metab. 2001;280(3):E509-17 - PMID: 11171607

In vitro and in vivo evaluation of albumin synthesis rate of porcine hepatocytes in a flat-plate bioreactor.

Shito M, Kim NH, Baskaran H, Tilles AW, Tompkins RG, Yarmush ML, Toner M
Artif Organs. 2001;25(7):571-8 - PMID: 11493279

Intrahepatic amino acid and glucose metabolism in a D-galactosamine-induced rat liver failure model.

Arai K, Lee K, Berthiaume F, Tompkins RG, Yarmush ML
Hepatology. 2001;34(2):360-71 - PMID: 11481621

Young age is not a predictor of mortality in burns.

Sheridan RL, Weber JM, Schnitzer JJ, Schulz JT, Ryan CM, Tompkins RG
Pediatr Crit Care Med. 2001;2(3):223-224 - PMID: 12793945

Antibiotic prophylaxis for group A streptococcal burn wound infection is not necessary.

Sheridan RL, Weber JM, Pasternack MS, Tompkins RG
J Trauma. 2001;51(2):352-5 - PMID: 11493799

Long-term maintenance of cytochrome P450 activities by rat hepatocyte/3T3 cell co-cultures in heparinized human plasma.

Washizu J, Berthiaume F, Mokuno Y, Tompkins RG, Toner M, Yarmush ML
Tissue Eng. 2001;7(6):691-703 - PMID: 11749727

Differential roles of the Pseudomonas aeruginosa PA14 rpoN gene in pathogenicity in plants, nematodes, insects, and mice.

Hendrickson EL, Plotnikova J, Mahajan-Miklos S, Rahme LG, Ausubel FM
J Bacteriol. 2001;183(24):7126-34 - PMID: 11717271 - PMCID: PMC95561

The roles of mucD and alginate in the virulence of Pseudomonas aeruginosa in plants, nematodes and mice.

Yorgey P, Rahme LG, Tan MW, Ausubel FM
Mol Microbiol. 2001;41(5):1063-76 - PMID: 11555287

The TASTY locus on chromosome 1 of Arabidopsis affects feeding of the insect herbivore Trichoplusia ni.

Jander G, Cui J, Nhan B, Pierce NE, Ausubel FM
Plant Physiol. 2001;126(2):890-8 - PMID: 11402216 - PMCID: PMC111178

One-step purification of recombinant proteins using a nanomolar-affinity streptavidin-binding peptide, the SBP-Tag.

Keefe AD, Wilson DS, Seelig B, Szostak JW
Protein Expr Purif. 2001;23(3):440-6 - PMID: 11722181

Functional proteins from a random-sequence library.

Keefe AD, Szostak JW
Nature. 2001;410(6829):715-8 - PMID: 11287961 - PMCID: PMC4476321

In vitro evolution suggests multiple origins for the hammerhead ribozyme.

Salehi-Ashtiani K, Szostak JW
Nature. 2001;414(6859):82-4 - PMID: 11689947

Synthesizing life.

Szostak JW, Bartel DP, Luisi PL
Nature. 2001;409(6818):387-90 - PMID: 11201752

The use of mRNA display to select high-affinity protein-binding peptides.

Wilson DS, Keefe AD, Szostak JW
Proc Natl Acad Sci U S A. 2001;98(7):3750-5 - PMID: 11274392 - PMCID: PMC31124

Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR.

Evron E, Dooley WC, Umbricht CB, Rosenthal D, Sacchi N, Gabrielson E, Soito AB, Hung DT, Ljung B, Davidson NE, Sukumar S
Lancet. 2001;357(9265):1335-6 - PMID: 11343741

Ductal lavage for detection of cellular atypia in women at high risk for breast cancer.

Dooley WC, Ljung BM, Veronesi U, Cazzaniga M, Elledge RM, O'Shaughnessy JA, Kuerer HM, Hung DT, Khan SA, Phillips RF, Ganz PA, Euhus DM, Esserman LJ, Haffty BG, King BL, Kelley MC, Anderson MM, Schmit PJ, Clark RR, Kass FC, Anderson BO, Troyan SL, Arias RD, Quiring JN, Love SM, Page DL, King EB
J Natl Cancer Inst. 2001;93(21):1624-32 - PMID: 11698566

Lipid rafts and pseudotyping.

Pickl WF, Pimentel-Muiños FX, Seed B
J Virol. 2001;75(15):7175-83 - PMID: 11435598 - PMCID: PMC114446

Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9.

Yang Y, Kuang Y, Montes De Oca R, Hays T, Moreau L, Lu N, Seed B, D'Andrea AD
Blood. 2001;98(12):3435-40 - PMID: 11719385

Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability.

Randow F, Seed B
Nat Cell Biol. 2001;3(10):891-6 - PMID: 11584270

Identification of two sequences in the cytoplasmic tail of the human immunodeficiency virus type 1 envelope glycoprotein that inhibit cell surface expression.

Bültmann A, Muranyi W, Seed B, Haas J
J Virol. 2001;75(11):5263-76 - PMID: 11333908 - PMCID: PMC114932

Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo.

Fukumura D, Xu L, Chen Y, Gohongi T, Seed B, Jain RK
Cancer Res. 2001;61(16):6020-4 - PMID: 11507045

The role of PPAR-gamma in macrophage differentiation and cholesterol uptake.

Moore KJ, Rosen ED, Fitzgerald ML, Randow F, Andersson LP, Altshuler D, Milstone DS, Mortensen RM, Spiegelman BM, Freeman MW
Nat Med. 2001;7(1):41-7 - PMID: 11135614

Manipulating intestinal cholesterol absorption and hepatic cholesterol and bile acid metabolism by activation of deorphanized nuclear receptors.

Rigotti A, Freeman MW
Gastroenterology. 2001;120(4):1054-5 - PMID: 11231965

ATP-binding cassette transporter A1 contains an NH2-terminal signal anchor sequence that translocates the protein's first hydrophilic domain to the exoplasmic space.

Fitzgerald ML, Mendez AJ, Moore KJ, Andersson LP, Panjeton HA, Freeman MW
J Biol Chem. 2001;276(18):15137-45 - PMID: 11328826

Evidence that dendritic cells infiltrate atherosclerotic lesions in apolipoprotein E-deficient mice.

Bobryshev YV, Taksir T, Lord RS, Freeman MW
Histol Histopathol. 2001;16(3):801-8 - PMID: 11510970

Peroxisome proliferator-activated receptors in macrophage biology: friend or foe?

Moore KJ, Fitzgerald ML, Freeman MW
Curr Opin Lipidol. 2001;12(5):519-27 - PMID: 11561171

LBP, CD14, TLR4 and the murine innate immune response to a peritoneal Salmonella infection.

Bernheiden M, Heinrich JM, Minigo G, Schütt C, Stelter F, Freeman M, Golenbock D, Jack RS
J Endotoxin Res. 2001;7(6):447-50 - PMID: 11753215

Initial sequencing and analysis of the human genome.

Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, Kann L, Lehoczky J, LeVine R, McEwan P, McKernan K, Meldrim J, Mesirov JP, Miranda C, Morris W, Naylor J, Raymond C, Rosetti M, Santos R, Sheridan A, Sougnez C, Stange-Thomann N, Stojanovic N, Subramanian A, Wyman D, Rogers J, Sulston J, Ainscough R, Beck S, Bentley D, Burton J, Clee C, Carter N, Coulson A, Deadman R, Deloukas P, Dunham A, Dun ...
Nature. 2001;409(6822):860-921 - PMID: 11237011

A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms.

Sachidanandam R, Weissman D, Schmidt SC, Kakol JM, Stein LD, Marth G, Sherry S, Mullikin JC, Mortimore BJ, Willey DL, Hunt SE, Cole CG, Coggill PC, Rice CM, Ning Z, Rogers J, Bentley DR, Kwok PY, Mardis ER, Yeh RT, Schultz B, Cook L, Davenport R, Dante M, Fulton L, Hillier L, Waterston RH, McPherson JD, Gilman B, Schaffner S, Van Etten WJ, Reich D, Higgins J, Daly MJ, Blumenstiel B, Baldwin J, Stange-Thomann N, Zody MC, Linton L, Lander ES, Altshuler D,
Nature. 2001;409(6822):928-33 - PMID: 11237013

Isoform-specific mutations in the Caenorhabditis elegans heterochronic gene lin-14 affect stage-specific patterning.

Reinhart BJ, Ruvkun G
Genetics. 2001;157(1):199-209 - PMID: 11139502 - PMCID: PMC1461488

Regulation of ectodermal and excretory function by the C. elegans POU homeobox gene ceh-6.

Bürglin TR, Ruvkun G
Development. 2001;128(5):779-90 - PMID: 11171402

Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family.

Pierce SB, Costa M, Wisotzkey R, Devadhar S, Homburger SA, Buchman AR, Ferguson KC, Heller J, Platt DM, Pasquinelli AA, Liu LX, Doberstein SK, Ruvkun G
Genes Dev. 2001;15(6):672-86 - PMID: 11274053 - PMCID: PMC312654

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing.

Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I, Baillie DL, Fire A, Ruvkun G, Mello CC
Cell. 2001;106(1):23-34 - PMID: 11461699

Molecular biology. Glimpses of a tiny RNA world.

Ruvkun G
Science. 2001;294(5543):797-9 - PMID: 11679654

The genetics of aging.

Finch CE, Ruvkun G
Annu Rev Genomics Hum Genet. 2001;2:435-62 - PMID: 11701657

Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway.

Lee RY, Hench J, Ruvkun G
Curr Biol. 2001;11(24):1950-7 - PMID: 11747821

Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing.

Aballay A, Ausubel FM
Proc Natl Acad Sci U S A. 2001;98(5):2735-9 - PMID: 11226309 - PMCID: PMC30208

A simple model host for identifying Gram-positive virulence factors.

Garsin DA, Sifri CD, Mylonakis E, Qin X, Singh KV, Murray BE, Calderwood SB, Ausubel FM
Proc Natl Acad Sci U S A. 2001;98(19):10892-7 - PMID: 11535834 - PMCID: PMC58570

Isochorismate synthase is required to synthesize salicylic acid for plant defence.

Wildermuth MC, Dewdney J, Wu G, Ausubel FM
Nature. 2001;414(6863):562-5 - PMID: 11734859

Mesophyll-specific, light and metabolic regulation of the C4 PPCZm1 promoter in transgenic maize.

Kausch AP, Owen TP, Zachwieja SJ, Flynn AR, Sheen J
Plant Mol Biol. 2001;45(1):1-15 - PMID: 11247600

Isotopic assays for reporter gene activity.

Kingston RE, Sheen J, Moore D
Curr Protoc Pharmacol. 2001;Chapter 6:Unit 6.4 - PMID: 21965075

Molecular identification of phenylalanine ammonia-lyase as a substrate of a specific constitutively active Arabidopsis CDPK expressed in maize protoplasts.

Cheng SH, Sheen J, Gerrish C, Bolwell GP
FEBS Lett. 2001;503(2-3):185-8 - PMID: 11513879

Two-component circuitry in Arabidopsis cytokinin signal transduction.

Hwang I, Sheen J
Nature. 2001;413(6854):383-9 - PMID: 11574878

Dissection of abscisic acid signal transduction pathways in barley aleurone layers.

Shen Q, Gomez-Cadenas A, Zhang P, Walker-Simmons MK, Sheen J, Ho TH
Plant Mol Biol. 2001;47(3):437-48 - PMID: 11587514

Plant mitogen-activated protein kinase signaling cascades.

Tena G, Asai T, Chiu WL, Sheen J
Curr Opin Plant Biol. 2001;4(5):392-400 - PMID: 11597496

Signal transduction in maize and Arabidopsis mesophyll protoplasts.

Sheen J
Plant Physiol. 2001;127(4):1466-75 - PMID: 11743090 - PMCID: PMC1540179

Introduction of plasmid DNA into cells.

Seidman CE, Struhl K, Sheen J, Jessen T
Curr Protoc Mol Biol. 2001;Chapter 1:Unit1.8 - PMID: 18265047

Isotopic assays for reporter gene activity.

Kingston RE, Sheen J, Moore D
Curr Protoc Mol Biol. 2001;Chapter 9:Unit9.7A - PMID: 18265285

Silanizing glassware.

Seed B
Curr Protoc Cell Biol. 2001;Appendix 3:Appendix 3E - PMID: 18228287

Silanizing glassware.

Seed B
Curr Protoc Mol Biol. 2001;Appendix 3:Appendix 3B - PMID: 18265032

Silanizing glassware.

Seed B
Curr Protoc Protein Sci. 2001;Appendix 3:Appendix 3E - PMID: 18429072

Silanizing glassware.

Seed B
Curr Protoc Immunol. 2001;Appendix 3:Appendix 3K - PMID: 18432662

Microbiology. How to get along--friendly microbes in a hostile world.

Xavier RJ, Podolsky DK
Science. 2000;289(5484):1483-4 - PMID: 10991734

Fractalkine is an epithelial and endothelial cell-derived chemoattractant for intraepithelial lymphocytes in the small intestinal mucosa.

Muehlhoefer A, Saubermann LJ, Gu X, Luedtke-Heckenkamp K, Xavier R, Blumberg RS, Podolsky DK, MacDermott RP, Reinecker HC
J Immunol. 2000;164(6):3368-76 - PMID: 10706732

Cutaneous herpetic infections complicating burns.

Sheridan RL, Schulz JT, Weber JM, Ryan CM, Pasternack MS, Tompkins RG
Burns. 2000;26(7):621-4 - PMID: 10925184

Management of severe toxic epidermal necrolysis in children.

Sheridan RL, Weber JM, Schulz JT, Ryan CM, Low HM, Tompkins RG
J Burn Care Rehabil. 2000;20(6):497-500 - PMID: 10613688

Current expectations for survival in pediatric burns.

Sheridan RL, Remensnyder JP, Schnitzer JJ, Schulz JT, Ryan CM, Tompkins RG
Arch Pediatr Adolesc Med. 2000;154(3):245-9 - PMID: 10710021

Amino acid supplementation improves cell-specific functions of the rat hepatocytes exposed to human plasma.

Washizu J, Chan C, Berthiaume F, Tompkins RG, Toner M, Yarmush ML
Tissue Eng. 2000;6(5):497-504 - PMID: 11074936

Optimization of rat hepatocyte culture in citrated human plasma.

Washizu J, Berthiaume F, Chan C, Tompkins RG, Toner M, Yarmush ML
J Surg Res. 2000;93(2):237-46 - PMID: 11027466

Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet.

Lyons J, Rauh-Pfeiffer A, Yu YM, Lu XM, Zurakowski D, Tompkins RG, Ajami AM, Young VR, Castillo L
Proc Natl Acad Sci U S A. 2000;97(10):5071-6 - PMID: 10792033 - PMCID: PMC25783

Artificial skin.

Schulz JT, Tompkins RG, Burke JF
Annu Rev Med. 2000;51:231-44 - PMID: 10774462

A 10-year experience with toxic epidermal necrolysis.

Schulz JT, Sheridan RL, Ryan CM, MacKool B, Tompkins RG
J Burn Care Rehabil. 2000;21(3):199-204 - PMID: 10850900

Long-term outcome of children surviving massive burns.

Sheridan RL, Hinson MI, Liang MH, Nackel AF, Schoenfeld DA, Ryan CM, Mulligan JL, Tompkins RG
JAMA. 2000;283(1):69-73 - PMID: 10632282

Positive correlation between virulence of Pseudomonas aeruginosa mutants in mice and insects.

Jander G, Rahme LG, Ausubel FM
J Bacteriol. 2000;182(13):3843-5 - PMID: 10851003 - PMCID: PMC94559

Elucidating the molecular mechanisms of bacterial virulence using non-mammalian hosts.

Mahajan-Miklos S, Rahme LG, Ausubel FM
Mol Microbiol. 2000;37(5):981-8 - PMID: 10972817

Caenorhabditis elegans: a model genetic host to study Pseudomonas aeruginosa pathogenesis.

Tan MW, Ausubel FM
Curr Opin Microbiol. 2000;3(1):29-34 - PMID: 10679415

Roles of salicylic acid, jasmonic acid, and ethylene in cpr-induced resistance in arabidopsis.

Clarke JD, Volko SM, Ledford H, Ausubel FM, Dong X
Plant Cell. 2000;12(11):2175-90 - PMID: 11090217 - PMCID: PMC150166

Three unique mutants of Arabidopsis identify eds loci required for limiting growth of a biotrophic fungal pathogen.

Dewdney J, Reuber TL, Wildermuth MC, Devoto A, Cui J, Stutius LM, Drummond EP, Ausubel FM
Plant J. 2000;24(2):205-18 - PMID: 11069695

Isolation and characterization of disease resistance gene homologues from rice cultivar IR64.

Ilag LL, Yadav RC, Huang N, Ronald PC, Ausubel FM
Gene. 2000;255(2):245-55 - PMID: 11024284

Simulation of fungal-mediated cell death by fumonisin B1 and selection of fumonisin B1-resistant (fbr) Arabidopsis mutants.

Stone JM, Heard JE, Asai T, Ausubel FM
Plant Cell. 2000;12(10):1811-22 - PMID: 11041878 - PMCID: PMC149121

The alternative sigma factor RpoN is required for hrp activity in Pseudomonas syringae pv. maculicola and acts at the level of hrpL transcription.

Hendrickson EL, Guevera P, Ausubel FM
J Bacteriol. 2000;182(12):3508-16 - PMID: 10852884 - PMCID: PMC101944

Virulence of the phytopathogen Pseudomonas syringae pv. maculicola is rpoN dependent.

Hendrickson EL, Guevera P, Peñaloza-Vàzquez A, Shao J, Bender C, Ausubel FM
J Bacteriol. 2000;182(12):3498-507 - PMID: 10852883 - PMCID: PMC101941

Mutational analysis of the Arabidopsis nucleotide binding site-leucine-rich repeat resistance gene RPS2.

Tao Y, Yuan F, Leister RT, Ausubel FM, Katagiri F
Plant Cell. 2000;12(12):2541-2554 - PMID: 11148296 - PMCID: PMC102236

Plants and animals share functionally common bacterial virulence factors.

Rahme LG, Ausubel FM, Cao H, Drenkard E, Goumnerov BC, Lau GW, Mahajan-Miklos S, Plotnikova J, Tan MW, Tsongalis J, Walendziewicz CL, Tompkins RG
Proc Natl Acad Sci U S A. 2000;97(16):8815-21 - PMID: 10922040 - PMCID: PMC34017

Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans.

Aballay A, Yorgey P, Ausubel FM
Curr Biol. 2000;10(23):1539-42 - PMID: 11114525

A simple procedure for the analysis of single nucleotide polymorphisms facilitates map-based cloning in Arabidopsis.

Drenkard E, Richter BG, Rozen S, Stutius LM, Angell NA, Mindrinos M, Cho RJ, Oefner PJ, Davis RW, Ausubel FM
Plant Physiol. 2000;124(4):1483-92 - PMID: 11115864 - PMCID: PMC1539302

Pathogenesis of the human opportunistic pathogen Pseudomonas aeruginosa PA14 in Arabidopsis.

Plotnikova JM, Rahme LG, Ausubel FM
Plant Physiol. 2000;124(4):1766-74 - PMID: 11115892 - PMCID: PMC59873

Arabidopsis genome. A milestone in plant biology.

Ausubel FM
Plant Physiol. 2000;124(4):1451-4 - PMID: 11115856 - PMCID: PMC1539293

In vitro selection and directed evolution.

Szostak JW
Harvey Lect. 2000;93:95-118 - PMID: 10941421

In vitro selection of functional nucleic acids.

Wilson DS, Szostak JW
Annu Rev Biochem. 2000;68:611-47 - PMID: 10872462

Constructing high complexity synthetic libraries of long ORFs using in vitro selection.

Cho G, Keefe AD, Liu R, Wilson DS, Szostak JW
J Mol Biol. 2000;297(2):309-19 - PMID: 10715203

Expanding the structural and functional diversity of RNA: analog uridine triphosphates as candidates for in vitro selection of nucleic acids.

Vaish NK, Fraley AW, Szostak JW, McLaughlin LW
Nucleic Acids Res. 2000;28(17):3316-22 - PMID: 10954600 - PMCID: PMC110695

Ribozyme-catalyzed tRNA aminoacylation.

Lee N, Bessho Y, Wei K, Szostak JW, Suga H
Nat Struct Biol. 2000;7(1):28-33 - PMID: 10625423

Optimized synthesis of RNA-protein fusions for in vitro protein selection.

Liu R, Barrick JE, Szostak JW, Roberts RW
Methods Enzymol. 2000;318:268-93 - PMID: 10889994

A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions.

Joung JK, Ramm EI, Pabo CO
Proc Natl Acad Sci U S A. 2000;97(13):7382-7 - PMID: 10852947 - PMCID: PMC16554

Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice.

Beck PL, Xavier R, Lu N, Nanda NN, Dinauer M, Podolsky DK, Seed B
Gastroenterology. 2000;119(3):699-705 - PMID: 10982764

Episomal segregation of the adenovirus enhancer sequence by conditional genome rearrangement abrogates late viral gene expression.

Wang X, Zeng W, Murakawa M, Freeman MW, Seed B
J Virol. 2000;74(23):11296-303 - PMID: 11070029 - PMCID: PMC113234

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule.

Holler N, Zaru R, Micheau O, Thome M, Attinger A, Valitutti S, Bodmer JL, Schneider P, Seed B, Tschopp J
Nat Immunol. 2000;1(6):489-95 - PMID: 11101870

What to do about high cholesterol

M Freeman, Consultant editor 2nd edition. PJ Skerret and SD Emond
President and Fellows of Harvard College. Harvard Health Publications. 2000;:ePub

Stromelysin-1 (MMP-3) expression driven by a macrophage-specific promoter results in reduced viability in transgenic mice.

Fabunmi RP, Moore KJ, Libby P, Freeman MW
Atherosclerosis. 2000;148(2):375-86 - PMID: 10657574

Lipopolysaccharide induces scavenger receptor A expression in mouse macrophages: a divergent response relative to human THP-1 monocyte/macrophages.

Fitzgerald ML, Moore KJ, Freeman MW, Reed GL
J Immunol. 2000;164(5):2692-700 - PMID: 10679110

Novel mutations in the gene encoding ATP-binding cassette 1 in four tangier disease kindreds.

Brousseau ME, Schaefer EJ, Dupuis J, Eustace B, Van Eerdewegh P, Goldkamp AL, Thurston LM, FitzGerald MG, Yasek-McKenna D, O'Neill G, Eberhart GP, Weiffenbach B, Ordovas JM, Freeman MW, Brown RH, Gu JZ
J Lipid Res. 2000;41(3):433-41 - PMID: 10706591

Cellular cholesterol efflux in heterozygotes for tangier disease is markedly reduced and correlates with high density lipoprotein cholesterol concentration and particle size.

Brousseau ME, Eberhart GP, Dupuis J, Asztalos BF, Goldkamp AL, Schaefer EJ, Freeman MW
J Lipid Res. 2000;41(7):1125-35 - PMID: 10884295

Divergent response to LPS and bacteria in CD14-deficient murine macrophages.

Moore KJ, Andersson LP, Ingalls RR, Monks BG, Li R, Arnaout MA, Golenbock DT, Freeman MW
J Immunol. 2000;165(8):4272-80 - PMID: 11035061

Episomal segregation of the adenovirus enhancer sequence by conditional genome rearrangement abrogates late viral gene expression.

Wang X, Zeng W, Murakawa M, Freeman MW, Seed B
J Virol. 2000;74(23):11296-303 - PMID: 11070029 - PMCID: PMC113234

Effects of overexpression of the amino-terminal fragment of apolipoprotein B on apolipoprotein B and lipoprotein production.

Li Z, Kako Y, Pang L, Freeman MW, Glick JM, Wang X, Goldberg IJ
J Lipid Res. 2000;41(12):1912-20 - PMID: 11108724

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.

Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP, Tripp RA, Walsh EE, Freeman MW, Golenbock DT, Anderson LJ, Finberg RW
Nat Immunol. 2000;1(5):398-401 - PMID: 11062499

Ancient adaptation of the active site of tryptophanyl-tRNA synthetase for tryptophan binding.

Praetorius-Ibba M, Stange-Thomann N, Kitabatake M, Ali K, Söll I, Carter CW, Ibba M, Söll D
Biochemistry. 2000;39(43):13136-43 - PMID: 11052665

A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum.

Tissenbaum HA, Hawdon J, Perregaux M, Hotez P, Guarente L, Ruvkun G
Proc Natl Acad Sci U S A. 2000;97(1):460-5 - PMID: 10618440 - PMCID: PMC26685

Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant.

Sze JY, Victor M, Loer C, Shi Y, Ruvkun G
Nature. 2000;403(6769):560-4 - PMID: 10676966

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans.

Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, Rougvie AE, Horvitz HR, Ruvkun G
Nature. 2000;403(6772):901-6 - PMID: 10706289

The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor.

Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G
Mol Cell. 2000;5(4):659-69 - PMID: 10882102

DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells.

Nasrin N, Ogg S, Cahill CM, Biggs W, Nui S, Dore J, Calvo D, Shi Y, Ruvkun G, Alexander-Bridges MC
Proc Natl Acad Sci U S A. 2000;97(19):10412-7 - PMID: 10973497 - PMCID: PMC27038

Regulation of C. elegans life-span by insulinlike signaling in the nervous system.

Wolkow CA, Kimura KD, Lee MS, Ruvkun G
Science. 2000;290(5489):147-50 - PMID: 11021802

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA.

Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kuroda MI, Maller B, Hayward DC, Ball EE, Degnan B, Müller P, Spring J, Srinivasan A, Fishman M, Finnerty J, Corbo J, Levine M, Leahy P, Davidson E, Ruvkun G
Nature. 2000;408(6808):86-9 - PMID: 11081512

Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways.

Cahill CM, Tzivion G, Nasrin N, Ogg S, Dore J, Ruvkun G, Alexander-Bridges M
J Biol Chem. 2000;276(16):13402-10 - PMID: 11124266

Graded expression of ceh-14 reporters in the hypodermis is induced by a gonadal signal.

Kagoshima H, Sommer R, Reinhart BJ, Cassata G, Ruvkun G, Bürglin TR
Dev Genes Evol. 2000;210(11):564-9 - PMID: 11180807

Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar.

Arenas-Huertero F, Arroyo A, Zhou L, Sheen J, León P
Genes Dev. 2000;14(16):2085-96 - PMID: 10950871 - PMCID: PMC316855

Fumonisin B1-induced cell death in arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways.

Asai T, Stone JM, Heard JE, Kovtun Y, Yorgey P, Sheen J, Ausubel FM
Plant Cell. 2000;12(10):1823-36 - PMID: 11041879 - PMCID: PMC149122

The role of hexokinase in plant sugar signal transduction and growth and development.

Xiao W, Sheen J, Jang JC
Plant Mol Biol. 2000;44(4):451-61 - PMID: 11197321

A paradoxical reduction in susceptibility to colonic injury upon targeted transgenic ablation of goblet cells.

Itoh H, Beck PL, Inoue N, Xavier R, Podolsky DK
J Clin Invest. 1999;104(11):1539-47 - PMID: 10587517 - PMCID: PMC409855

Laser ablation of burns: initial clinical trial.

Sheridan RL, Lydon MM, Petras LM, Schomacker KT, Tompkins RG, Glatter RD, Parrish JA
Surgery. 1999;125(1):92-5 - PMID: 9889803

Acute hand burns in children: management and long-term outcome based on a 10-year experience with 698 injured hands.

Sheridan RL, Baryza MJ, Pessina MA, O'Neill KM, Cipullo HM, Donelan MB, Ryan CM, Schulz JT, Schnitzer JJ, Tompkins RG
Ann Surg. 1999;229(4):558-64 - PMID: 10203090 - PMCID: PMC1191743

Skin substitutes in burns.

Sheridan RL, Tompkins RG
Burns. 1999;25(2):97-103 - PMID: 10208382

A unique mechanism of desensitization to lipolysis mediated by beta(3)-adrenoceptor in rats with thermal injury.

Ikezu T, Yasuhara S, Granneman JG, Kraemer FB, Okamoto T, Tompkins RG, Martyn JA
Am J Physiol. 1999;277(2 Pt 1):E316-24 - PMID: 10444428

Cutaneous burn injury alters relative tricarboxylic acid cycle fluxes in rat liver.

Yarmush DM, MacDonald AD, Foy BD, Berthiaume F, Tompkins RG, Yarmush ML
J Burn Care Rehabil. 1999;20(4):292-302 - PMID: 10425591

Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine: effects of transamination and transmethylation.

Carter EA, Yu YM, Alpert NM, Bonab AA, Tompkins RG, Fischman AJ
J Trauma. 1999;47(2):341-5 - PMID: 10452471

Low-dose inhaled nitric oxide in acutely burned children with profound respiratory failure.

Sheridan RL, Zapol WM, Ritz RH, Tompkins RG
Surgery. 1999;126(5):856-62 - PMID: 10568185

A 15-year experience with varicella infections in a pediatric burn unit.

Sheridan RL, Weber JM, Pasternak MM, Mulligan JM, Tompkins RG
Burns. 1999;25(4):353-6 - PMID: 10431985

The metabolic basis of the increase of the increase in energy expenditure in severely burned patients.

Yu YM, Tompkins RG, Ryan CM, Young VR
JPEN J Parenter Enteral Nutr. 1999;23(3):160-8 - PMID: 10338224

Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors.

Tan MW, Rahme LG, Sternberg JA, Tompkins RG, Ausubel FM
Proc Natl Acad Sci U S A. 1999;96(5):2408-13 - PMID: 10051655 - PMCID: PMC26797

Genome-wide mapping with biallelic markers in Arabidopsis thaliana.

Cho RJ, Mindrinos M, Richards DR, Sapolsky RJ, Anderson M, Drenkard E, Dewdney J, Reuber TL, Stammers M, Federspiel N, Theologis A, Yang WH, Hubbell E, Au M, Chung EY, Lashkari D, Lemieux B, Dean C, Lipshutz RJ, Ausubel FM, Davis RW, Oefner PJ
Nat Genet. 1999;23(2):203-7 - PMID: 10508518

Arabidopsis thaliana PAD4 encodes a lipase-like gene that is important for salicylic acid signaling.

Jirage D, Tootle TL, Reuber TL, Frost LN, Feys BJ, Parker JE, Ausubel FM, Glazebrook J
Proc Natl Acad Sci U S A. 1999;96(23):13583-8 - PMID: 10557364 - PMCID: PMC23991

Isolation and characterization of fluorophore-binding RNA aptamers.

Holeman LA, Robinson SL, Szostak JW, Wilson C
Fold Des. 1999;3(6):423-31 - PMID: 9889155

Membrane compartmentation and the response to antigen.

Xavier R, Seed B
Curr Opin Immunol. 1999;11(3):265-9 - PMID: 10375560

The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activation.

Izumi KM, Cahir McFarland ED, Ting AT, Riley EA, Seed B, Kieff ED
Mol Cell Biol. 1999;19(8):5759-67 - PMID: 10409763 - PMCID: PMC84426

Regulated commitment of TNF receptor signaling: a molecular switch for death or activation.

Pimentel-Muiños FX, Seed B
Immunity. 1999;11(6):783-93 - PMID: 10626900

Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion.

Chiang N, Gronert K, Clish CB, O'Brien JA, Freeman MW, Serhan CN
J Clin Invest. 1999;104(3):309-16 - PMID: 10430612 - PMCID: PMC408424

Effluxed lipids: Tangier Island's latest export.

Freeman MW
Proc Natl Acad Sci U S A. 1999;96(20):10950-2 - PMID: 10500104 - PMCID: PMC34222

A conserved LIM protein that affects muscular adherens junction integrity and mechanosensory function in Caenorhabditis elegans.

Hobert O, Moerman DG, Clark KA, Beckerle MC, Ruvkun G
J Cell Biol. 1999;144(1):45-57 - PMID: 9885243 - PMCID: PMC2148118

The Caenorhabditis elegans lim-6 LIM homeobox gene regulates neurite outgrowth and function of particular GABAergic neurons.

Hobert O, Tessmar K, Ruvkun G
Development. 1999;126(7):1547-62 - PMID: 10068647

Pax genes in Caenorhabditis elegans: a new twist.

Hobert O, Ruvkun G
Trends Genet. 1999;15(6):214-6 - PMID: 10354580

A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans.

Paradis S, Ailion M, Toker A, Thomas JH, Ruvkun G
Genes Dev. 1999;13(11):1438-52 - PMID: 10364160 - PMCID: PMC316759

Alternative olfactory neuron fates are specified by the LIM homeobox gene lim-4.

Sagasti A, Hobert O, Troemel ER, Ruvkun G, Bargmann CI
Genes Dev. 1999;13(14):1794-806 - PMID: 10421632 - PMCID: PMC316880

Themes from a NASA workshop on gene regulatory processes in development and evolution.

Davidson EH, Ruvkun G
J Exp Zool. 1999;285(2):104-15 - PMID: 10440721

Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model.

Mahajan-Miklos S, Tan MW, Rahme LG, Ausubel FM
Cell. 1999;96(1):47-56 - PMID: 9989496

Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis.

Tan MW, Mahajan-Miklos S, Ausubel FM
Proc Natl Acad Sci U S A. 1999;96(2):715-20 - PMID: 9892699 - PMCID: PMC15202

C4 GENE EXPRESSION.

Sheen J
Annu Rev Plant Physiol Plant Mol Biol. 1999;50():187-217 - PMID: 15012208

Health information in the developing world.

Lown B, Bukachi F, Xavier R
Lancet. 1998;352 Suppl 2:SII34-8 - PMID: 9798645

SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development.

Swat W, Fujikawa K, Ganiatsas S, Yang D, Xavier RJ, Harris NL, Davidson L, Ferrini R, Davis RJ, Labow MA, Flavell RA, Zon LI, Alt FW
Immunity. 1998;8(5):625-34 - PMID: 9620683

Characterization of a composite tissue model that supports clonal growth of human melanocytes in vitro and in vivo.

Medalie DA, Tompkins RG, Morgan JR
J Invest Dermatol. 1998;111(5):810-6 - PMID: 9804343

Genetically modified human keratinocytes overexpressing PDGF-A enhance the performance of a composite skin graft.

Eming SA, Medalie DA, Tompkins RG, Yarmush ML, Morgan JR
Hum Gene Ther. 1998;9(4):529-39 - PMID: 9525314

Objective estimates of the probability of death from burn injuries.

Ryan CM, Schoenfeld DA, Thorpe WP, Sheridan RL, Cassem EH, Tompkins RG
N Engl J Med. 1998;338(6):362-6 - PMID: 9449729

Maximal parenteral glucose oxidation in hypermetabolic young children: a stable isotope study.

Sheridan RL, Yu YM, Prelack K, Young VR, Burke JF, Tompkins RG
JPEN J Parenter Enteral Nutr. 1998;22(4):212-6 - PMID: 9661121

A rabbit model for metabolic studies after burn injury.

Hu RH, Yu YM, Costa D, Young VR, Ryan CM, Burke JF, Tompkins RG
J Surg Res. 1998;75(2):153-60 - PMID: 9655088

Death in the burn unit: sterile multiple organ failure.

Sheridan RL, Ryan CM, Yin LM, Hurley J, Tompkins RG
Burns. 1998;24(4):307-11 - PMID: 9688194

Muscle protein synthesis by positron-emission tomography with L-[methyl-11C]methionine in adult humans.

Fischman AJ, Yu YM, Livni E, Babich JW, Young VR, Alpert NM, Tompkins RG
Proc Natl Acad Sci U S A. 1998;95(22):12793-8 - PMID: 9788993 - PMCID: PMC23595

Both C3a and C3a(desArg) regulate interleukin-6 synthesis in human peripheral blood mononuclear cells.

Takabayashi T, Vannier E, Burke JF, Tompkins RG, Gelfand JA, Clark BD
J Infect Dis. 1998;177(6):1622-8 - PMID: 9607842

Modulation of expression of the ToxR regulon in Vibrio cholerae by a member of the two-component family of response regulators.

Wong SM, Carroll PA, Rahme LG, Ausubel FM, Calderwood SB
Infect Immun. 1998;66(12):5854-61 - PMID: 9826365 - PMCID: PMC108741

A light-independent developmental mechanism potentiates flavonoid gene expression in Arabidopsis seedlings.

Kubasek WL, Ausubel FM, Shirley BW
Plant Mol Biol. 1998;37(2):217-23 - PMID: 9617795

Use of Arabidopsis for genetic dissection of plant defense responses.

Glazebrook J, Rogers EE, Ausubel FM
Annu Rev Genet. 1998;31:547-69 - PMID: 9442907

The epidemiology of resistance to ofloxacin and oxacillin among clinical coagulase-negative staphylococcal isolates: analysis of risk factors and strain types.

Pegues DA, Colby C, Hibberd PL, Cohen LG, Ausubel FM, Calderwood SB, Hooper DC
Clin Infect Dis. 1998;26(1):72-9 - PMID: 9455512

Isolation of new Arabidopsis mutants with enhanced disease susceptibility to Pseudomonas syringae by direct screening.

Volko SM, Boller T, Ausubel FM
Genetics. 1998;149(2):537-48 - PMID: 9611172 - PMCID: PMC1460196

Use of cleaved amplified polymorphic sequences (CAPS) as genetic markers in Arabidopsis thaliana.

Glazebrook J, Drenkard E, Preuss D, Ausubel FM
Methods Mol Biol. 1998;82:173-82 - PMID: 9664424

Structural and kinetic characterization of an acyl transferase ribozyme.

Suga H, Lohse PA, Szostak JW
J Am Chem Soc. 1998;120(6):1151-6 - PMID: 11541113

Unusual metal ion catalysis in an acyl-transferase ribozyme.

Suga H, Cowan JA, Szostak JW
Biochemistry. 1998;37(28):10118-25 - PMID: 9665717

Isolation of a fluorophore-specific DNA aptamer with weak redox activity.

Wilson C, Szostak JW
Chem Biol. 1998;5(11):609-17 - PMID: 9831529

PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines.

Jiang C, Ting AT, Seed B
Nature. 1998;391(6662):82-6 - PMID: 9422509

Increased immune response elicited by DNA vaccination with a synthetic gp120 sequence with optimized codon usage.

André S, Seed B, Eberle J, Schraut W, Bültmann A, Haas J
J Virol. 1998;72(2):1497-503 - PMID: 9445053 - PMCID: PMC124631

Membrane compartmentation is required for efficient T cell activation.

Xavier R, Brennan T, Li Q, McCormack C, Seed B
Immunity. 1998;8(6):723-32 - PMID: 9655486

Muskelin, a novel intracellular mediator of cell adhesive and cytoskeletal responses to thrombospondin-1.

Adams JC, Seed B, Lawler J
EMBO J. 1998;17(17):4964-74 - PMID: 9724633 - PMCID: PMC1170825

PPARgamma and colorectal carcinoma: conflicts in a nuclear family.

Seed B
Nat Med. 1998;4(9):1004-5 - PMID: 9734386

Tumor induction of VEGF promoter activity in stromal cells.

Fukumura D, Xavier R, Sugiura T, Chen Y, Park EC, Lu N, Selig M, Nielsen G, Taksir T, Jain RK, Seed B
Cell. 1998;94(6):715-25 - PMID: 9753319

Decreased cholesterol efflux from fibroblasts of a patient without Tangier disease, but with markedly reduced high density lipoprotein cholesterol levels.

Eberhart GP, Mendez AJ, Freeman MW
J Clin Endocrinol Metab. 1998;83(3):836-46 - PMID: 9506737

Functional changes in scavenger receptor binding conformation are induced by charge mutants spanning the entire collagen domain.

Andersson L, Freeman MW
J Biol Chem. 1998;273(31):19592-601 - PMID: 9677385

In vitro-differentiated embryonic stem cell macrophages: a model system for studying atherosclerosis-associated macrophage functions.

Moore KJ, Fabunmi RP, Andersson LP, Freeman MW
Arterioscler Thromb Vasc Biol. 1998;18(10):1647-54 - PMID: 9763539

Temporal pattern formation by heterochronic genes.

Slack F, Ruvkun G
Annu Rev Genet. 1998;31:611-34 - PMID: 9442909

An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans.

Tissenbaum HA, Ruvkun G
Genetics. 1998;148(2):703-17 - PMID: 9504918 - PMCID: PMC1459840

Control of neural development and function in a thermoregulatory network by the LIM homeobox gene lin-11.

Hobert O, D'Alberti T, Liu Y, Ruvkun G
J Neurosci. 1998;18(6):2084-96 - PMID: 9482795

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor.

Paradis S, Ruvkun G
Genes Dev. 1998;12(16):2488-98 - PMID: 9716402 - PMCID: PMC317081

Aging, life span, and senescence.

Guarente L, Ruvkun G, Amasino R
Proc Natl Acad Sci U S A. 1998;95(19):11034-6 - PMID: 9736682 - PMCID: PMC33892

The taxonomy of developmental control in Caenorhabditis elegans.

Ruvkun G, Hobert O
Science. 1998;282(5396):2033-41 - PMID: 9851920

A novel repeat domain that is often associated with RING finger and B-box motifs.

Slack FJ, Ruvkun G
Trends Biochem Sci. 1998;23(12):474-5 - PMID: 9868369

The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway.

Ogg S, Ruvkun G
Mol Cell. 1998;2(6):887-93 - PMID: 9885576

Heterochronic genes in development and evolution.

Slack F, Ruvkun G
Biol Bull. 1998;195(3):375-6 - PMID: 9924779

A common theme for LIM homeobox gene function across phylogeny?

Hobert O, Ruvkun G
Biol Bull. 1998;195(3):377-80 - PMID: 9924780

Correlation of defense gene induction defects with powdery mildew susceptibility in Arabidopsis enhanced disease susceptibility mutants.

Reuber TL, Plotnikova JM, Dewdney J, Rogers EE, Wood W, Ausubel FM
Plant J. 1998;16(4):473-85 - PMID: 9881167

The role of proinflammatory cytokines in inflammatory and metabolic responses.

Tompkins RG
Ann Surg. 1997;225(3):243-5 - PMID: 9060578 - PMCID: PMC1190672

Differences in dermal analogs influence subsequent pigmentation, epidermal differentiation, basement membrane, and rete ridge formation of transplanted composite skin grafts.

Medalie DA, Eming SA, Collins ME, Tompkins RG, Yarmush ML, Morgan JR
Transplantation. 1997;64(3):454-65 - PMID: 9275113

Urinary urea nitrogen is imprecise as a predictor of protein balance in burned children.

Prelack K, Dwyer J, Yu YM, Sheridan RL, Tompkins RG
J Am Diet Assoc. 1997;97(5):489-95 - PMID: 9145086

Evaluation of acellular human dermis as a dermal analog in a composite skin graft.

Medalie DA, Tompkins RG, Morgan JR
ASAIO J. 1997;42(5):M455-62 - PMID: 8944923

Burns in children younger than two years of age: an experience with 200 consecutive admissions.

Sheridan RL, Ryan CM, Petras LM, Lydon MK, Weber JM, Tompkins RG
Pediatrics. 1997;100(4):721-3 - PMID: 9310533

Effect of burn injury on glucose and nitrogen metabolism in the liver: preliminary studies in a perfused liver system.

Yamaguchi Y, Yu YM, Zupke C, Yarmush DM, Berthiaume F, Tompkins RG, Yarmush ML
Surgery. 1997;121(3):295-303 - PMID: 9092130

TCA cycle flux estimates from NMR- and GC-MS-determined [13C]glutamate isotopomers in liver.

Vogt JA, Yarmush DM, Yu YM, Zupke C, Fischman AJ, Tompkins RG, Burke JF
Am J Physiol. 1997;272(6 Pt 1):C2049-62 - PMID: 9227434

Analysis of thermal injury-induced insulin resistance in rodents. Implication of postreceptor mechanisms.

Ikezu T, Okamoto T, Yonezawa K, Tompkins RG, Martyn JA
J Biol Chem. 1997;272(40):25289-95 - PMID: 9312146

Metabolic alterations in muscle of thermally injured rabbits, measured by positron emission tomography.

Carter EA, Tompkins RG, Hsu H, Christian B, Alpert NM, Weise S, Fischman AJ
Life Sci. 1997;61(1):39-44 - PMID: 9200667

Energy and protein provisions for thermally injured children revisited: an outcome-based approach for determining requirements.

Prelack K, Cunningham JJ, Sheridan RL, Tompkins RG
J Burn Care Rehabil. 1997;18(2):177-81; discussion 176 - PMID: 9095430

Localization of radiolabeled chemotactic peptide at focal sites of Escherichia coli infection in rabbits: evidence for a receptor-specific mechanism.

Babich JW, Tompkins RG, Graham W, Barrow SA, Fischman AJ
J Nucl Med. 1997;38(8):1316-22 - PMID: 9255175

Ice formation in isolated human hepatocytes and human liver tissue.

Bischof JC, Ryan CM, Tompkins RG, Yarmush ML, Toner M
ASAIO J. 1997;43(4):271-8 - PMID: 9242939

Control of hypertrophic scar growth using selective photothermolysis.

Reiken SR, Wolfort SF, Berthiaume F, Compton C, Tompkins RG, Yarmush ML
Lasers Surg Med. 1997;21(1):7-12 - PMID: 9228634

Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells.

Aiura K, Clark BD, Dinarello CA, Margolis NH, Kaplanski G, Burke JF, Tompkins RG, Gelfand JA
J Infect Dis. 1997;175(1):123-9 - PMID: 8985205

Nosocomial infections in pediatric patients with burns.

Weber JM, Sheridan RL, Pasternack MS, Tompkins RG
Am J Infect Control. 1997;25(3):195-201 - PMID: 9202814

Inhaled nitric oxide in burn patients with respiratory failure.

Sheridan RL, Hurford WE, Kacmarek RM, Ritz RH, Yin LM, Ryan CM, Tompkins RG
J Trauma. 1997;42(4):629-34 - PMID: 9137249

Inactivation of the alpha C protein antigen gene, bca, by a novel shuttle/suicide vector results in attenuation of virulence and immunity in group B Streptococcus.

Li J, Kasper DL, Ausubel FM, Rosner B, Michel JL
Proc Natl Acad Sci U S A. 1997;94(24):13251-6 - PMID: 9371832 - PMCID: PMC24295

Isolation of novel ribozymes that ligate AMP-activated RNA substrates.

Hager AJ, Szostak JW
Chem Biol. 1997;4(8):607-17 - PMID: 9281527

Introduction: Combinatorial Chemistry.

Szostak JW
Chem Rev. 1997;97(2):347-348 - PMID: 11848873

RNA-peptide fusions for the in vitro selection of peptides and proteins.

Roberts RW, Szostak JW
Proc Natl Acad Sci U S A. 1997;94(23):12297-302 - PMID: 9356443 - PMCID: PMC24913

Mutant ATP-binding RNA aptamers reveal the structural basis for ligand binding.

Dieckmann T, Butcher SE, Sassanfar M, Szostak JW, Feigon J
J Mol Biol. 1997;273(2):467-78 - PMID: 9344753

In vitro selection of catalytic RNAs.

Chapman KB, Szostak JW
Curr Opin Struct Biol. 1997;4:618-22 - PMID: 11539575

Domestic violence: old problems, new approaches.

Stuart LM
Links (Oxford). 1997;:4 - PMID: 12320799

Activation of prokaryotic transcription through arbitrary protein-protein contacts.

Dove SL, Joung JK, Hochschild A
Nature. 1997;386(6625):627-30 - PMID: 9121589

Integrins and inside-out signal transduction: converging signals from PKC and PIP3.

Kolanus W, Seed B
Curr Opin Cell Biol. 1997;9(5):725-31 - PMID: 9330877

Scavenger receptors in atherosclerosis.

Freeman MW
Curr Opin Hematol. 1997;4(1):41-7 - PMID: 9050378

A nuclear genetic lesion affecting Saccharomyces cerevisiae mitochondrial translation is complemented by a homologous Bacillus gene.

Kim SI, Stange-Thomann N, Martins O, Hong KW, Söll D, Fox TD
J Bacteriol. 1997;179(17):5625-7 - PMID: 9287027 - PMCID: PMC179443

VP16-activation of the C. elegans neural specification transcription factor UNC-86 suppresses mutations in downstream genes and causes defects in neural migration and axon outgrowth.

Sze JY, Liu Y, Ruvkun G
Development. 1997;124(6):1159-68 - PMID: 9102303

The Caenorhabditis elegans orphan nuclear hormone receptor gene nhr-2 functions in early embryonic development.

Sluder AE, Lindblom T, Ruvkun G
Dev Biol. 1997;184(2):303-19 - PMID: 9133437

Regulation of interneuron function in the C. elegans thermoregulatory pathway by the ttx-3 LIM homeobox gene.

Hobert O, Mori I, Yamashita Y, Honda H, Ohshima Y, Liu Y, Ruvkun G
Neuron. 1997;19(2):345-57 - PMID: 9292724

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans.

Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G
Science. 1997;277(5328):942-6 - PMID: 9252323

The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway.

Patterson GI, Koweek A, Wong A, Liu Y, Ruvkun G
Genes Dev. 1997;11(20):2679-90 - PMID: 9334330 - PMCID: PMC316611

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans.

Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA, Ruvkun G
Nature. 1997;389(6654):994-9 - PMID: 9353126

Arabidopsis enhanced disease susceptibility mutants exhibit enhanced susceptibility to several bacterial pathogens and alterations in PR-1 gene expression.

Rogers EE, Ausubel FM
Plant Cell. 1997;9(3):305-16 - PMID: 9090877 - PMCID: PMC156920

Phytoalexin-deficient mutants of Arabidopsis reveal that PAD4 encodes a regulatory factor and that four PAD genes contribute to downy mildew resistance.

Glazebrook J, Zook M, Mert F, Kagan I, Rogers EE, Crute IR, Holub EB, Hammerschmidt R, Ausubel FM
Genetics. 1997;146(1):381-92 - PMID: 9136026 - PMCID: PMC1207952

Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors.

Rahme LG, Tan MW, Le L, Wong SM, Tompkins RG, Calderwood SB, Ausubel FM
Proc Natl Acad Sci U S A. 1997;94(24):13245-50 - PMID: 9371831 - PMCID: PMC24294

Paracoccidioidomycosis of bones and joints. A clinical, radiologic, and pathologic study of 9 cases.

Amstalden EM, Xavier R, Kattapuram SV, Bertolo MB, Swartz MN, Rosenberg AE
Medicine (Baltimore). 1996;75(4):213-25 - PMID: 8699961

Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors.

Liang TJ, Reid AE, Xavier R, Cardiff RD, Wang TC
J Clin Invest. 1996;97(12):2872-7 - PMID: 8675700 - PMCID: PMC507382

Effective postoperative protection for grafted posterior surfaces: the quilted dressing.

Sheridan RL, Behringer GE, Ryan CM, Bondoc CC, Quinby WC, Tompkins RG, Burke JF
J Burn Care Rehabil. 1996;16(6):607-9 - PMID: 8582939

Evaluation of human skin reconstituted from composite grafts of cultured keratinocytes and human acellular dermis transplanted to athymic mice.

Medalie DA, Eming SA, Tompkins RG, Yarmush ML, Krueger GG, Morgan JR
J Invest Dermatol. 1996;107(1):121-7 - PMID: 8752850

Planimetry study of the percent of body surface represented by the hand and palm: sizing irregular burns is more accurately done with the palm.

Sheridan RL, Petras L, Basha G, Salvo P, Cifrino C, Hinson M, McCabe M, Fallon J, Tompkins RG
J Burn Care Rehabil. 1996;16(6):605-6 - PMID: 8582938

Kinetics of plasma arginine and leucine in pediatric burn patients.

Yu YM, Sheridan RL, Burke JF, Chapman TE, Tompkins RG, Young VR
Am J Clin Nutr. 1996;64(1):60-6 - PMID: 8669415

Extracorporeal plasma perfusion of cultured hepatocytes: effect of intermittent perfusion on hepatocyte function and morphology.

Stefanovich P, Matthew HW, Toner M, Tompkins RG, Yarmush ML
J Surg Res. 1996;66(1):57-63 - PMID: 8954832

Management strategy in purpura fulminans with multiple organ failure in children.

Sheridan RL, Briggs SE, Remensnyder JP, Tompkins RG
Burns. 1996;22(1):53-6 - PMID: 8719318

Decreased cerebral glucose utilization in rats during the ebb phase of thermal injury.

Carter EA, Tompkins RG, Babich JW, Correia JA, Fischman AJ
J Trauma. 1996;40(6):930-5 - PMID: 8656479

Thermal injury in rats alters glucose utilization by skin, wound, and small intestine, but not by skeletal muscle.

Carter EA, Tompkins RG, Babich JW, Correia J, Bailey EM, Fischman AJ
Metabolism. 1996;45(9):1161-7 - PMID: 8781305

Accelerated healing and reduced need for grafting in pediatric patients with burns treated with arginine-glycine-aspartic acid peptide matrix. RGD Study Group.

Hansbrough JF, Herndon DN, Heimbach DM, Solem LD, Gamelli RL, Tompkins RG
J Burn Care Rehabil. 1996;16(4):377-87 - PMID: 8582916

Burn depth estimation by use of indocyanine green fluorescence: initial human trial.

Sheridan RL, Schomaker KT, Lucchina LC, Hurley J, Yin LM, Tompkins RG, Jerath M, Torri A, Greaves KW, Bua DP
J Burn Care Rehabil. 1996;16(6):602-4 - PMID: 8582937

Culture matrix configuration and composition in the maintenance of hepatocyte polarity and function.

Moghe PV, Berthiaume F, Ezzell RM, Toner M, Tompkins RG, Yarmush ML
Biomaterials. 1996;17(3):373-85 - PMID: 8745335

Recent clinical experience with cultured autologous epithelium.

Sheridan RL, Tompkins RG
Br J Plast Surg. 1996;49(1):72-4 - PMID: 8705108

Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine.

Hsu H, Yu YM, Babich JW, Burke JF, Livni E, Tompkins RG, Young VR, Alpert NM, Fischman AJ
Proc Natl Acad Sci U S A. 1996;93(5):1841-6 - PMID: 8700846 - PMCID: PMC39869

Quantitative aspects of interorgan relationships among arginine and citrulline metabolism.

Yu YM, Burke JF, Tompkins RG, Martin R, Young VR
Am J Physiol. 1996;271(6 Pt 1):E1098-109 - PMID: 8997231

Comparative evaluation of the quantitative utilization of parenterally and enterally administered leucine and L-[1-13C,15N]leucine within the whole body and the splanchnic region.

Yu YM, Young VR, Tompkins RG, Burke JF
JPEN J Parenter Enteral Nutr. 1996;19(3):209-15 - PMID: 8551649

Candidemia in the pediatric patient with burns.

Sheridan RL, Weber JM, Budkevich LG, Tompkins RG
J Burn Care Rehabil. 1996;16(4):440-3 - PMID: 8582925

Control of hypertrophic scar growth using antibody-targeted photolysis.

Wolfort SF, Reiken SR, Berthiaume F, Tompkins RG, Yarmush ML
J Surg Res. 1996;62(1):17-22 - PMID: 8606503

Mode of action of the Arabidopsis thaliana phytoalexin camalexin and its role in Arabidopsis-pathogen interactions.

Rogers EE, Glazebrook J, Ausubel FM
Mol Plant Microbe Interact. 1996;9(8):748-57 - PMID: 8870273

Isolation of Arabidopsis genes that differentiate between resistance responses mediated by the RPS2 and RPM1 disease resistance genes.

Reuber TL, Ausubel FM
Plant Cell. 1996;8(2):241-9 - PMID: 8742710 - PMCID: PMC161094

Molecular recognition of pathogen attack occurs inside of plant cells in plant disease resistance specified by the Arabidopsis genes RPS2 and RPM1.

Leister RT, Ausubel FM, Katagiri F
Proc Natl Acad Sci U S A. 1996;93(26):15497-502 - PMID: 8986840 - PMCID: PMC26433

Use of cleaved amplified polymorphic sequences to distinguish strains of Staphylococcus epidermidis.

Calderwood SB, Baker MA, Carroll PA, Michel JL, Arbeit RD, Ausubel FM
J Clin Microbiol. 1996;34(11):2860-5 - PMID: 8897202 - PMCID: PMC229423

Differential mRNA display.

Reuber TL, Ausubel FM
Methods Cell Biol. 1996;49:431-40 - PMID: 8531774

Ribozymes: aiming at RNA replication and protein synthesis.

Hager AJ, Pollard JD, Szostak JW
Chem Biol. 1996;3(9):717-25 - PMID: 8939686

Kinetic and mechanistic analysis of nonenzymatic, template-directed oligoribonucleotide ligation.

Rohatgi R, Bartel DP, Szostak JW
J Am Chem Soc. 1996;118(14):3332-9 - PMID: 11539267

Ribozyme-catalysed amino-acid transfer reactions.

Lohse PA, Szostak JW
Nature. 1996;381(6581):442-4 - PMID: 8632803

Chance and necessity in the selection of nucleic acid catalysts.

Lorsch JR, Szostak JW
Acc Chem Res. 1996;29(2):103-10 - PMID: 11539421

A simple method for 3'-labeling of RNA.

Huang Z, Szostak JW
Nucleic Acids Res. 1996;24(21):4360-1 - PMID: 8932396 - PMCID: PMC146232

Nonenzymatic, template-directed ligation of oligoribonucleotides is highly regioselective for the formation of 3'-5' phosphodiester bonds.

Rohatgi R, Bartel DP, Szostak JW
J Am Chem Soc. 1996;118(14):3340-4 - PMID: 11539268

A soldier in respiratory distress.

Stuart LM, Rice PS, Lloyd G, Beale RJ
Lancet. 1996;347(8993):30 - PMID: 8531548

Deep inelastic scattering of polarized electrons by polarized 3He and the study of the neutron spin structure.

Anthony PL, Arnold RG, Band HR, Borel H, Bosted PE, Breton V, Cates GD, Chupp TE, Dietrich FS, Dunne J, Erbacher R, Fellbaum J, Fonvieille H, Gearhart R, Holmes R, Hughes EW, Johnson JR, Kawall D, Keppel C, Kuhn SE, Lombard-Nelsen RM, Marroncle J, Maruyama T, Meyer W, Meziani Z, Middleton H, Morgenstern J, Newbury NR, Petratos GG, Pitthan R, Prepost R, Roblin Y, Rock SE, Rokni SH, Shapiro G, Smith T, Souder PA, Spengos M, Staley F, Stuart LM, Szalata ZM, Terrien Y, Thompson AK, White JL, Woo ...
Phys Rev D Part Fields. 1996;54(11):6620-6650 - PMID: 10020671

(+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest.

Hung DT, Chen J, Schreiber SL
Chem Biol. 1996;3(4):287-93 - PMID: 8807856

Understanding and controlling the cell cycle with natural products.

Hung DT, Jamison TF, Schreiber SL
Chem Biol. 1996;3(8):623-39 - PMID: 8807895

Clustered syk tyrosine kinase domains trigger phagocytosis.

Greenberg S, Chang P, Wang DC, Xavier R, Seed B
Proc Natl Acad Sci U S A. 1996;93(3):1103-7 - PMID: 8577722 - PMCID: PMC40038

Codon usage limitation in the expression of HIV-1 envelope glycoprotein.

Haas J, Park EC, Seed B
Curr Biol. 1996;6(3):315-24 - PMID: 8805248

Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule.

Kolanus W, Nagel W, Schiller B, Zeitlmann L, Godar S, Stockinger H, Seed B
Cell. 1996;86(2):233-42 - PMID: 8706128

RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis.

Ting AT, Pimentel-Muiños FX, Seed B
EMBO J. 1996;15(22):6189-96 - PMID: 8947041 - PMCID: PMC452440

Expression of the macrophage scavenger receptor, a multifunctional lipoprotein receptor, in microglia associated with senile plaques in Alzheimer's disease.

Christie RH, Freeman M, Hyman BT
Am J Pathol. 1996;148(2):399-403 - PMID: 8579103 - PMCID: PMC1861668

Substrate selection by aminoacyl-tRNA synthetases.

Ibba M, Thomann HU, Hong KW, Sherman JM, Weygand-Durasevic I, Sever S, Stange-Thomann N, Praetorius M, Söll D
Nucleic Acids Symp Ser. 1996;(33):40-2 - PMID: 8643392

Lineage-specific regulators couple cell lineage asymmetry to the transcription of the Caenorhabditis elegans POU gene unc-86 during neurogenesis.

Baumeister R, Liu Y, Ruvkun G
Genes Dev. 1996;10(11):1395-410 - PMID: 8647436

The Caenorhabditis elegans behavioral gene unc-24 encodes a novel bipartite protein similar to both erythrocyte band 7.2 (stomatin) and nonspecific lipid transfer protein.

Barnes TM, Jin Y, Horvitz HR, Ruvkun G, Hekimi S
J Neurochem. 1996;67(1):46-57 - PMID: 8667025

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans.

Morris JZ, Tissenbaum HA, Ruvkun G
Nature. 1996;382(6591):536-9 - PMID: 8700226

A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation.

Ha I, Wightman B, Ruvkun G
Genes Dev. 1996;10(23):3041-50 - PMID: 8957004

Isolation of Arabidopsis mutants with enhanced disease susceptibility by direct screening.

Glazebrook J, Rogers EE, Ausubel FM
Genetics. 1996;143(2):973-82 - PMID: 8725243 - PMCID: PMC1207353

Effects of plasma exposure on cultured hepatocytes: Implications for bioartificial liver support.

Matthew HW, Sternberg J, Stefanovich P, Morgan JR, Toner M, Tompkins RG, Yarmush ML
Biotechnol Bioeng. 1996;51(1):100-11 - PMID: 18627093

Malignant epithelioid hemangioendothelioma of the tibia associated with a bone infarct in a patient who had Gaucher disease. A case report.

Pins MR, Mankin HJ, Xavier RJ, Rosenthal DI, Dickersin GR, Rosenberg AE
J Bone Joint Surg Am. 1995;77(5):777-81 - PMID: 7744904

Enzyme replacement therapy for Gaucher disease: skeletal responses to macrophage-targeted glucocerebrosidase.

Rosenthal DI, Doppelt SH, Mankin HJ, Dambrosia JM, Xavier RJ, McKusick KA, Rosen BR, Baker J, Niklason LT, Hill SC
Pediatrics. 1995;96(4 Pt 1):629-37 - PMID: 7567322

Atheroembolic renal failure after invasive procedures. Natural history based on 52 histologically proven cases.

Thadhani RI, Camargo CA, Xavier RJ, Fang LS, Bazari H
Medicine (Baltimore). 1995;74(6):350-8 - PMID: 7500898

Modified Stryker frame for intraoperative positioning of the patient with burns.

Sheridan RL, Hurley J, Lynch L, Balmer J, Ryan CM, Bondoc CC, Quinby WC, Tompkins RG, Burke JF
J Burn Care Rehabil. 1995;15(5):438-40 - PMID: 7995819

The burn unit as a resource for the management of acute nonburn conditions in children.

Sheridan RL, Briggs SE, Remensnyder JP, Gagnon SW, Doody DP, Ryan DP, Tompkins RG
J Burn Care Rehabil. 1995;16(1):62-4 - PMID: 7721912

Central venous catheter sepsis with weekly catheter change in paediatric burn patients: an analysis of 221 catheters.

Sheridan RL, Weber JM, Peterson HF, Tompkins RG
Burns. 1995;21(2):127-9 - PMID: 7766321

Permissive hypercapnia as a ventilatory strategy in burned children: effect on barotrauma, pneumonia, and mortality.

Sheridan RL, Kacmarek RM, McEttrick MM, Weber JM, Ryan CM, Doody DP, Ryan DP, Schnitzer JJ, Tompkins RG
J Trauma. 1995;39(5):854-9 - PMID: 7474000

Intraoperative reflectance oximetry in burn patients.

Sheridan RL, Prelack KM, Petras LM, Szyfelbein SK, Tompkins RG
J Clin Monit. 1995;11(1):32-4 - PMID: 7745451

Strategies for success in academic surgery.

Souba WW, Gamelli RL, Lorber MI, Thompson JS, Kron IL, Tompkins RG, Hoyt DB
Surgery. 1995;117(1):90-5 - PMID: 7809842

Relations among arginine, citrulline, ornithine, and leucine kinetics in adult burn patients.

Yu YM, Ryan CM, Burke JF, Tompkins RG, Young VR
Am J Clin Nutr. 1995;62(5):960-8 - PMID: 7572742

Postburn pancreatitis.

Ryan CM, Sheridan RL, Schoenfeld DA, Warshaw AL, Tompkins RG
Ann Surg. 1995;222(2):163-70 - PMID: 7543741 - PMCID: PMC1234774

Effects of malignancy and interleukin-2 infusion on gut macromolecular permeability.

Ryan CM, Atkins MB, Mier JW, Gelfand JA, Tompkins RG
Crit Care Med. 1995;23(11):1801-6 - PMID: 7587254

Retrovirus infection: effect of time and target cell number.

Morgan JR, LeDoux JM, Snow RG, Tompkins RG, Yarmush ML
J Virol. 1995;69(11):6994-7000 - PMID: 7474118 - PMCID: PMC189618

Detection of acute bacterial infection within soft tissue injuries using a 99mTc-labeled chemotactic peptide.

Fischman AJ, Babich JW, Barrow SA, Graham W, Carter E, Tompkins RG, Rubin RH
J Trauma. 1995;38(2):223-7 - PMID: 7869440

Plasma arginine and leucine kinetics and urea production rates in burn patients.

Yu YM, Young VR, Castillo L, Chapman TE, Tompkins RG, Ryan CM, Burke JF
Metabolism. 1995;44(5):659-66 - PMID: 7752916

Cultured autologous epithelium in patients with burns of ninety percent or more of the body surface.

Sheridan RL, Tompkins RG
J Trauma. 1995;38(1):48-50 - PMID: 7745657

Percutaneous cholecystostomy in the critically ill burn patient.

Sheridan RL, Ryan CM, Lee MJ, Mueller PR, Tompkins RG
J Trauma. 1995;38(2):248-51 - PMID: 7869446

Dynamics of photoinduced cell plasma membrane injury.

Thorpe WP, Toner M, Ezzell RM, Tompkins RG, Yarmush ML
Biophys J. 1995;68(5):2198-206 - PMID: 7612864 - PMCID: PMC1282125

Dynamics of cell membrane permeability changes at supraphysiological temperatures.

Bischof JC, Padanilam J, Holmes WH, Ezzell RM, Lee RC, Tompkins RG, Yarmush ML, Toner M
Biophys J. 1995;68(6):2608-14 - PMID: 7647264 - PMCID: PMC1282171

Genetically modified human epidermis overexpressing PDGF-A directs the development of a cellular and vascular connective tissue stroma when transplanted to athymic mice--implications for the use of genetically modified keratinocytes to modulate dermal regeneration.

Eming SA, Lee J, Snow RG, Tompkins RG, Yarmush ML, Morgan JR
J Invest Dermatol. 1995;105(6):756-63 - PMID: 7490468

Effects of hypothermia on the function, membrane integrity, and cytoskeletal structure of hepatocytes.

Stefanovich P, Ezzell RM, Sheehan SJ, Tompkins RG, Yarmush ML, Toner M
Cryobiology. 1995;32(4):389-403 - PMID: 7656572

A device to measure the oxygen uptake rate of attached cells: importance in bioartificial organ design.

Foy BD, Rotem A, Toner M, Tompkins RG, Yarmush ML
Cell Transplant. 1995;3(6):515-27 - PMID: 7881763

The acutely burned hand: management and outcome based on a ten-year experience with 1047 acute hand burns.

Sheridan RL, Hurley J, Smith MA, Ryan CM, Bondoc CC, Quinby WC, Tompkins RG, Burke JF
J Trauma. 1995;38(3):406-11 - PMID: 7897728

Emergency management of major hydrofluoric acid exposures.

Sheridan RL, Ryan CM, Quinby WC, Blair J, Tompkins RG, Burke JF
Burns. 1995;21(1):62-4 - PMID: 7718123

Midazolam infusion in pediatric patients with burns who are undergoing mechanical ventilation.

Sheridan RL, McEttrick M, Bacha G, Stoddard F, Tompkins RG
J Burn Care Rehabil. 1995;15(6):515-8 - PMID: 7852455

Solid organ procurement from burn patients.

Sheridan RL, Stewart B, Tompkins RG
J Trauma. 1995;38(5):824-5 - PMID: 7760420

Clinical experience with the use of biodegradable tacks in pediatric patients with burns.

Sheridan RL, Petras L, Basha G, Tompkins RG
J Burn Care Rehabil. 1995;16(2 Pt 1):143-4 - PMID: 7775509

Molecular genetics of plant disease resistance.

Staskawicz BJ, Ausubel FM, Baker BJ, Ellis JG, Jones JD
Science. 1995;268(5211):661-7 - PMID: 7732374

Analysis of Arabidopsis mutants deficient in flavonoid biosynthesis.

Shirley BW, Kubasek WL, Storz G, Bruggemann E, Koornneef M, Ausubel FM, Goodman HM
Plant J. 1995;8(5):659-71 - PMID: 8528278

Use of Arabidopsis thaliana defense-related mutants to dissect the plant response to pathogens.

Ausubel FM, Katagiri F, Mindrinos M, Glazebrook J
Proc Natl Acad Sci U S A. 1995;92(10):4189-96 - PMID: 7753782 - PMCID: PMC41909

A DNA metalloenzyme with DNA ligase activity.

Cuenoud B, Szostak JW
Nature. 1995;375(6532):611-4 - PMID: 7791880

Isolation of a ribozyme with 5'-5' ligase activity.

Chapman KB, Szostak JW
Chem Biol. 1995;2(5):325-33 - PMID: 9383434

Structurally complex and highly active RNA ligases derived from random RNA sequences.

Ekland EH, Szostak JW, Bartel DP
Science. 1995;269(5222):364-70 - PMID: 7618102

Total chemical synthesis of a ribozyme derived from a group I intron.

Whoriskey SK, Usman N, Szostak JW
Proc Natl Acad Sci U S A. 1995;92(7):2465-9 - PMID: 7708666 - PMCID: PMC42238

Reverse transcriptase reads through a 2'-5'linkage and a 2'-thiophosphate in a template.

Lorsch JR, Bartel DP, Szostak JW
Nucleic Acids Res. 1995;23(15):2811-4 - PMID: 7544885 - PMCID: PMC307115

Kinetic and thermodynamic characterization of the reaction catalyzed by a polynucleotide kinase ribozyme.

Lorsch JR, Szostak JW
Biochemistry. 1995;34(46):15315-27 - PMID: 7578148

A DNA aptamer that binds adenosine and ATP.

Huizenga DE, Szostak JW
Biochemistry. 1995;34(2):656-65 - PMID: 7819261

In vitro evolution of a self-alkylating ribozyme.

Wilson C, Szostak JW
Nature. 1995;374(6525):777-82 - PMID: 7723823

RNA aptamers that bind flavin and nicotinamide redox cofactors.

Lauhon CT, Szostak JW
J Am Chem Soc. 1995;117(4):1246-57 - PMID: 11539282

Genetic strategy for analyzing specificity of dimer formation: Escherichia coli cyclic AMP receptor protein mutant altered in its dimerization specificity.

Joung JK, Chung EH, King G, Yu C, Hirsh AS, Hochschild A
Genes Dev. 1995;9(23):2986-96 - PMID: 7498794

Nonreceptor tyrosine kinases in aggregation-mediated cell activation.

Seed B, Kolanus W, Romeo C, Xavier R
Adv Exp Med Biol. 1995;365:111-9 - PMID: 7887297

Initiation of signal transduction by receptor aggregation: role of nonreceptor tyrosine kinases.

Seed B
Semin Immunol. 1995;7(1):3-11 - PMID: 7612893

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death.

Stanger BZ, Leder P, Lee TH, Kim E, Seed B
Cell. 1995;81(4):513-23 - PMID: 7538908

Developments in expression cloning.

Seed B
Curr Opin Biotechnol. 1995;6(5):567-73 - PMID: 7579669

PSGL-1 recognition of P-selectin is controlled by a tyrosine sulfation consensus at the PSGL-1 amino terminus.

Pouyani T, Seed B
Cell. 1995;83(2):333-43 - PMID: 7585950

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination.

Li Z, Otevrel T, Gao Y, Cheng HL, Seed B, Stamato TD, Taccioli GE, Alt FW
Cell. 1995;83(7):1079-89 - PMID: 8548796

Screening for hyperlipidemia. In: Goroll A, May L, Mulley A, eds

Haydock GS and MW Freeman
1995. 1995;Primary Care Medicine, 3rd Edit:72-75

Regulation of smooth muscle cell scavenger receptor expression in vivo by atherogenic diets and in vitro by cytokines.

Li H, Freeman MW, Libby P
J Clin Invest. 1995;95(1):122-33 - PMID: 7814605 - PMCID: PMC295387

Structure of the murine macrophage scavenger receptor gene and evaluation of sequences that regulate expression in the macrophage cell line, P388D.

Aftring RP, Freeman MW
J Lipid Res. 1995;36(6):1305-14 - PMID: 7666008

Common virulence factors for bacterial pathogenicity in plants and animals.

Rahme LG, Stevens EJ, Wolfort SF, Shao J, Tompkins RG, Ausubel FM
Science. 1995;268(5219):1899-902 - PMID: 7604262

The activity of cytochrome P450IA1 in stable cultured rat hepatocytes.

Rotem A, Matthew HW, Hsiao PH, Toner M, Tompkins RG, Yarmush ML
Toxicol In Vitro. 1995;9(2):139-49 - PMID: 20650073

Feedback control of gene expression.

Sheen J
Photosynth Res. 1994;39(3):427-38 - PMID: 24311134

Control of methicillin-resistant Staphylococcus aureus in a pediatric burn unit.

Sheridan RL, Weber J, Benjamin J, Pasternack MS, Tompkins RG
Am J Infect Control. 1994;22(6):340-5 - PMID: 7695112

Human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome.

Tompkins RG
Crit Care Med. 1994;22(1):3 - PMID: 8124969

Staphylococcal toxic shock syndrome in a paediatric burn unit.

Bacha EA, Sheridan RL, Donohue GA, Tompkins RG
Burns. 1994;20(6):499-502 - PMID: 7880413

Prognostic significance of prehospital cardiac or pulmonary resuscitation in paediatric burns patients.

Sheridan RL, Tompkins RG
Burns. 1994;20(3):265-6 - PMID: 8054145

Rapid quantitation of recombinant retroviruses.

Morgan JR, Lee J, Tompkins RG, Yarmush ML
Biotechnol Prog. 1994;10(4):441-6 - PMID: 7765097

Antibody Targeted Photolysis.

Yarmush ML, Thorpe WP, Strong L, Rakestraw SL, Toner M, Tompkins RG
Crit Rev Ther Drug Carrier Syst. 1994;10(3):197-252 - PMID: 8258158

Management of burn wounds with prompt excision and immediate closure.

Sheridan RL, Tompkins RG, Burke JF
J Intensive Care Med. 1994;9(1):6-17 - PMID: 10146651

Transport of fluorescent dextrans across the rat ileum after cutaneous thermal injury.

Berthiaume F, Ezzell RM, Toner M, Yarmush ML, Tompkins RG
Crit Care Med. 1994;22(3):455-64 - PMID: 7510222

Nitric oxide production is intensely and persistently increased in tissue by thermal injury.

Carter EA, Derojas-Walker T, Tamir S, Tannenbaum SR, Yu YM, Tompkins RG
Biochem J. 1994;304 ( Pt 1):201-4 - PMID: 7528006 - PMCID: PMC1137472

Arterial blood pressure immediately after thermal injury: the role of anesthesia.

Trop M, Carter EA, Schiffrin EJ, Tompkins RG
J Burn Care Rehabil. 1994;15(3):224-31 - PMID: 8056811

Additive effects of thermal injury and infection on gut permeability.

Ryan CM, Bailey SH, Carter EA, Schoenfeld DA, Tompkins RG
Arch Surg. 1994;129(3):325-8 - PMID: 8129610

Injury-induced inhibition of fat absorption.

Carter EA, Tompkins RG
J Burn Care Rehabil. 1994;15(2):154-7 - PMID: 8195256

Thermal injury induces very early production of interleukin-1 alpha in the rat by mechanisms other than endotoxemia.

Mester M, Carter EA, Tompkins RG, Gelfand JA, Dinarello CA, Burke JF, Clark BD
Surgery. 1994;115(5):588-96 - PMID: 8178258

A quantitative model of invasive Pseudomonas infection in burn injury.

Stevens EJ, Ryan CM, Friedberg JS, Barnhill RL, Yarmush ML, Tompkins RG
J Burn Care Rehabil. 1994;15(3):232-5 - PMID: 8056812

The use of pentafluorophenyl derivatives for the 18F labelling of proteins.

Herman LW, Fischman AJ, Tompkins RG, Hanson RN, Byon C, Strauss HW, Elmaleh DR
Nucl Med Biol. 1994;21(7):1005-10 - PMID: 9234356

Synthesis of 2-[18F]fluoro-2-deoxy-L-glucose and positron emission tomography studies in monkeys.

Meng J, Elmaleh DR, Jyawook S, Weiss S, Alpert NM, Babich JW, Tompkins RG, Fischman AJ
Nucl Med Biol. 1994;21(4):633-40 - PMID: 9234321

Antisense DNA delivery in vivo: liver targeting by receptor-mediated uptake.

Lu XM, Fischman AJ, Jyawook SL, Hendricks K, Tompkins RG, Yarmush ML
J Nucl Med. 1994;35(2):269-75 - PMID: 8294998

Antibody-targeted photolysis of bacteria in vivo.

Berthiaume F, Reiken SR, Toner M, Tompkins RG, Yarmush ML
Biotechnology (N Y). 1994;12(7):703-6 - PMID: 7764916

Assessment of artificial liver support technology.

Yarmush ML, Dunn JC, Tompkins RG
Cell Transplant. 1994;1(5):323-41 - PMID: 1344305

Long-term functional recovery of hepatocytes after cryopreservation in a three-dimensional culture configuration.

Borel Rinkes IH, Toner M, Sheeha SJ, Tompkins RG, Yarmush ML
Cell Transplant. 1994;1(4):281-92 - PMID: 1344301

An extracorporeal microscopy perfusion chamber for on-line studies of environmental effects on cultured hepatocytes.

Borel Rinkes IH, Toner M, Tompkins RG, Yarmush ML
J Biomech Eng. 1994;116(2):135-9 - PMID: 8078319

Selective adhesion of hepatocytes on patterned surfaces.

Bhatia SN, Toner M, Tompkins RG, Yarmush ML
Ann N Y Acad Sci. 1994;745:187-209 - PMID: 7832508

A general model for analysis of the tricarboxylic acid cycle with use of [13C]glutamate isotopomer measurements.

Vogt JA, Fischman AJ, Kempf M, Yu YM, Tompkins RG, Burke JF
Am J Physiol. 1994;266(6 Pt 1):E1012-22 - PMID: 7912892

Prophylactic antibiotics and their role in the prevention of surgical wound infection.

Sheridan RL, Tompkins RG, Burke JF
Adv Surg. 1994;27:43-65 - PMID: 8140979

Intracompartmental sepsis in burn patients.

Sheridan RL, Tompkins RG, McManus WF, Pruitt BA
J Trauma. 1994;36(3):301-5 - PMID: 8145308

Effectiveness of poloxamer 188 in arresting calcein leakage from thermally damaged isolated skeletal muscle cells.

Padanilam JT, Bischof JC, Lee RC, Cravalho EG, Tompkins RG, Yarmush ML, Toner M
Ann N Y Acad Sci. 1994;720:111-23 - PMID: 7516633

Femoral arterial catheterization in paediatric burn patients.

Sheridan RL, Weber JM, Tompkins RG
Burns. 1994;20(5):451-2 - PMID: 7999277

Cellular distribution of endotoxin after injection of chemically purified lipopolysaccharide differs from that after injection of live bacteria.

Ge Y, Ezzell RM, Tompkins RG, Warren HS
J Infect Dis. 1994;169(1):95-104 - PMID: 8277203

Haplotypic divergence coupled with lack of diversity at the Arabidopsis thaliana alcohol dehydrogenase locus: roles for both balancing and directional selection?

Hanfstingl U, Berry A, Kellogg EA, Costa JT, Rüdiger W, Ausubel FM
Genetics. 1994;138(3):811-28 - PMID: 7851777 - PMCID: PMC1206230

In vitro evolution of new ribozymes with polynucleotide kinase activity.

Lorsch JR, Szostak JW
Nature. 1994;371(6492):31-6 - PMID: 7521014

Suppression of mutations in the core of the Tetrahymena ribozyme by spermidine, ethanol and by substrate stabilization.

Hanna M, Szostak JW
Nucleic Acids Res. 1994;22(24):5326-31 - PMID: 7816622 - PMCID: PMC332078

Evidence that the guanosine substrate of the Tetrahymena ribozyme is bound in the anti conformation and that N7 contributes to binding.

Lin CW, Hanna M, Szostak JW
Biochemistry. 1994;33(9):2703-7 - PMID: 8117735

1H NMR studies of the high-affinity Rev binding site of the Rev responsive element of HIV-1 mRNA: base pairing in the core binding element.

Peterson RD, Bartel DP, Szostak JW, Horvath SJ, Feigon J
Biochemistry. 1994;33(18):5357-66 - PMID: 8180157

In vitro genetic analysis of the hinge region between helical elements P5-P4-P6 and P7-P3-P8 in the sunY group I self-splicing intron.

Green R, Szostak JW
J Mol Biol. 1994;235(1):140-55 - PMID: 7507168

In vitro selection of RNA aptamers specific for cyanocobalamin.

Lorsch JR, Szostak JW
Biochemistry. 1994;33(4):973-82 - PMID: 7508262

Measurements of the electric and magnetic form factors of the proton from Q2=1.75 to 8.83 (GeV/c)2.

Andivahis L, Bosted PE, Lung A, Stuart LM, Alster J, Arnold RG, Chang CC, Dietrich FS, Dodge W, Gearhart R, Gomez J, Griffioen KA, Hicks RS, Hyde-Wright CE, Keppel C, Kuhn SE, Lichtenstadt J, Miskimen RA, Peterson GA, Petratos GG, Rock SE, Rokni S, Sakumoto WK, Spengos M, Swartz K, Szalata Z, Tao LH
Phys Rev D Part Fields. 1994;50(9):5491-5517 - PMID: 10018207

Synergistic activation of transcription by bacteriophage lambda cI protein and E. coli cAMP receptor protein.

Joung JK, Koepp DM, Hochschild A
Science. 1994;265(5180):1863-6 - PMID: 8091212

Distinct binding and cellular properties of synthetic (+)- and (-)-discodermolides.

Hung DT, Nerenberg JB, Schreiber SL
Chem Biol. 1994;1(1):67-71 - PMID: 9383372

4A11, a monoclonal antibody recognizing a novel antigen expressed on aberrant vascular endothelium. Upregulation in an in vivo model of contact dermatitis.

Koch AE, Nickoloff BJ, Holgersson J, Seed B, Haines GK, Burrows JC, Leibovich SJ
Am J Pathol. 1994;144(2):244-59 - PMID: 8311112 - PMCID: PMC1887152

Association of Raf with the CD3 delta and gamma chains of the T cell receptor-CD3 complex.

Loh C, Romeo C, Seed B, Bruder JT, Rapp U, Rao A
J Biol Chem. 1994;269(12):8817-25 - PMID: 8132616

Making agonists of antagonists.

Seed B
Chem Biol. 1994;1(3):125-9 - PMID: 9383381

Of mice, men and cholesterol

Aftring RP and MW Freeman
Hepatology. 1994;19:1054-1056

Macrophage scavenger receptors

MW Freeman
Current Opinions in Lipidology . 1994;5:143-148

Macrophage scavenger receptors.

Freeman MW
Curr Opin Lipidol. 1994;5(2):143-8 - PMID: 8044417

Of mice, men and cholesterol.

Aftring RP, Freeman MW
Hepatology. 1994;19(4):1054-6 - PMID: 8138246

A point mutation in Euglena gracilis chloroplast tRNA(Glu) uncouples protein and chlorophyll biosynthesis.

Stange-Thomann N, Thomann HU, Lloyd AJ, Lyman H, Söll D
Proc Natl Acad Sci U S A. 1994;91(17):7947-51 - PMID: 8058739 - PMCID: PMC44521

daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans.

Gottlieb S, Ruvkun G
Genetics. 1994;137(1):107-20 - PMID: 8056303 - PMCID: PMC1205929

Targeted mutations in the Caenorhabditis elegans POU homeo box gene ceh-18 cause defects in oocyte cell cycle arrest, gonad migration, and epidermal differentiation.

Greenstein D, Hird S, Plasterk RH, Andachi Y, Kohara Y, Wang B, Finney M, Ruvkun G
Genes Dev. 1994;8(16):1935-48 - PMID: 7958868

Programmed cell death in plants: a pathogen-triggered response activated coordinately with multiple defense functions.

Greenberg JT, Guo A, Klessig DF, Ausubel FM
Cell. 1994;77(4):551-63 - PMID: 8187175

Isolation of phytoalexin-deficient mutants of Arabidopsis thaliana and characterization of their interactions with bacterial pathogens.

Glazebrook J, Ausubel FM
Proc Natl Acad Sci U S A. 1994;91(19):8955-9 - PMID: 8090752 - PMCID: PMC44725

The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats.

Mindrinos M, Katagiri F, Yu GL, Ausubel FM
Cell. 1994;78(6):1089-99 - PMID: 7923358

Oxygen is a factor determining in vitro tissue assembly: Effects on attachment and spreading of hepatocytes.

Rotem A, Toner M, Bhatia S, Foy BD, Tompkins RG, Yarmush ML
Biotechnol Bioeng. 1994;43(7):654-60 - PMID: 18615765

Engineering organ perfusion protocols: NMR analysis of hepatocyte isolation from perfused rat liver.

Foy BD, Toner M, Tompkins RG, Yarmush ML
Biotechnol Bioeng. 1994;43(7):661-72 - PMID: 18615766

Peroxynitrite-induced rat colitis--a new model of colonic inflammation.

Rachmilewitz D, Stamler JS, Karmeli F, Mullins ME, Singel DJ, Loscalzo J, Xavier RJ, Podolsky DK
Gastroenterology. 1993;105(6):1681-8 - PMID: 8253344

Flavobacterial sepsis in massively burned pediatric patients.

Sheridan RL, Ryan CM, Pasternack MS, Weber JM, Tompkins RG
Clin Infect Dis. 1993;17(2):185-7 - PMID: 8399864

Dishwasher effluent burns in infants.

Sheridan RL, Sheridan MG, Tompkins RG
Pediatrics. 1993;91(1):142-4 - PMID: 8416479

Hepatocytes from rat liver perfusions. Physicochemical effects on polyribosome size.

Dunn JC, Friedberg JS, Tompkins RG, Yarmush ML
ASAIO J. 1993;38(4):841-5 - PMID: 1450483

An effective technique of scrotal harvest.

Sheridan RL, Ryan CM, Tompkins RG
J Burn Care Rehabil. 1993;14(5):557-8 - PMID: 8245111

Gut macromolecular permeability in pancreatitis correlates with severity of disease in rats.

Ryan CM, Schmidt J, Lewandrowski K, Compton CC, Rattner DW, Warshaw AL, Tompkins RG
Gastroenterology. 1993;104(3):890-5 - PMID: 8440440

Burn wound closure using permanent skin replacement materials.

Tompkins RG, Burke JF
World J Surg. 1993;16(1):47-52 - PMID: 1290266

Isolation and long-term culture of human hepatocytes.

Ryan CM, Carter EA, Jenkins RL, Sterling LM, Yarmush ML, Malt RA, Tompkins RG
Surgery. 1993;113(1):48-54 - PMID: 8417488

In vivo bioactivity and biodistribution of chemotactic peptide analogs in nonhuman primates.

Fischman AJ, Rauh D, Solomon H, Babich JW, Tompkins RG, Kroon D, Strauss HW, Rubin RH
J Nucl Med. 1993;34(12):2130-4 - PMID: 8254400

Technetium-99m-labeled chemotactic peptides: comparison with indium-111-labeled white blood cells for localizing acute bacterial infection in the rabbit.

Babich JW, Graham W, Barrow SA, Dragotakes SC, Tompkins RG, Rubin RH, Fischman AJ
J Nucl Med. 1993;34(12):2176-81 - PMID: 8254406

Absence of change in hepatic lactate metabolism after burn injury.

Carter EA, Khalid MA, Burke JF, Tompkins RG
Burns. 1993;19(6):475-8 - PMID: 8292229

Core body temperature responses immediately after cutaneous thermal injury in rats.

Trop M, Tompkins RG, Schiffrin EJ, Carter EA, Burke JF
J Burn Care Rehabil. 1993;13(6):632-8 - PMID: 1469027

Thermal injury-induced changes in the rat intestine brush border cytoskeleton.

Ezzell RM, Carter EA, Yarmush ML, Tompkins RG
Surgery. 1993;114(3):591-7 - PMID: 8367816

Proline-mediated enhancement of hepatocyte function in a collagen gel sandwich culture configuration.

Lee J, Morgan JR, Tompkins RG, Yarmush ML
FASEB J. 1993;7(6):586-91 - PMID: 8472895

Intestinal production of interleukin-1 alpha during endotoxemia in the mouse.

Mester M, Tompkins RG, Gelfand JA, Dinarello CA, Burke JF, Clark BD
J Surg Res. 1993;54(6):584-91 - PMID: 8412068

Nucleation and growth of ice crystals inside cultured hepatocytes during freezing in the presence of dimethyl sulfoxide.

Karlsson JO, Cravalho EG, Borel Rinkes IH, Tompkins RG, Yarmush ML, Toner M
Biophys J. 1993;65(6):2524-36 - PMID: 8312489 - PMCID: PMC1225995

Acute adrenal insufficiency in the burn intensive care unit.

Sheridan RL, Ryan CM, Tompkins RG
Burns. 1993;19(1):63-6 - PMID: 8435119

Nonequilibrium freezing of one-cell mouse embryos. Membrane integrity and developmental potential.

Toner M, Cravalho EG, Stachecki J, Fitzgerald T, Tompkins RG, Yarmush ML, Armant DR
Biophys J. 1993;64(6):1908-21 - PMID: 8369414 - PMCID: PMC1262525

Immobilized IL-2 preserves the viability of an IL-2 dependent cell line.

Horwitz JI, Toner M, Tompkins RG, Yarmush ML
Mol Immunol. 1993;30(11):1041-8 - PMID: 8350874

Technetium-99m-labeled hydrazino nicotinamide derivatized chemotactic peptide analogs for imaging focal sites of bacterial infection.

Babich JW, Solomon H, Pike MC, Kroon D, Graham W, Abrams MJ, Tompkins RG, Rubin RH, Fischman AJ
J Nucl Med. 1993;34(11):1964-74 - PMID: 8229242

Effect of collagen gel configuration on the cytoskeleton in cultured rat hepatocytes.

Ezzell RM, Toner M, Hendricks K, Dunn JC, Tompkins RG, Yarmush ML
Exp Cell Res. 1993;208(2):442-52 - PMID: 8375473

Signal transduction mutants of Arabidopsis uncouple nuclear CAB and RBCS gene expression from chloroplast development.

Susek RE, Ausubel FM, Chory J
Cell. 1993;74(5):787-99 - PMID: 7690685

Arabidopsis mutants compromised for the control of cellular damage during pathogenesis and aging.

Greenberg JT, Ausubel FM
Plant J. 1993;4(2):327-41 - PMID: 8220484

An Arabidopsis thaliana lipoxygenase gene can be induced by pathogens, abscisic acid, and methyl jasmonate.

Melan MA, Dong X, Endara ME, Davis KR, Ausubel FM, Peterman TK
Plant Physiol. 1993;101(2):441-50 - PMID: 7506426 - PMCID: PMC160590

An RNA motif that binds ATP.

Sassanfar M, Szostak JW
Nature. 1993;364(6437):550-3 - PMID: 7687750

Ribozyme-catalyzed primer extension by trinucleotides: a model for the RNA-catalyzed replication of RNA.

Doudna JA, Usman N, Szostak JW
Biochemistry. 1993;32(8):2111-5 - PMID: 7680575

Isolation of new ribozymes from a large pool of random sequences [see comment].

Bartel DP, Szostak JW
Science. 1993;261(5127):1411-8 - PMID: 7690155

Ribozymes. Evolution ex vivo.

Szostak JW
Nature. 1993;361(6408):119-20 - PMID: 7678448

Measurements of the electric and magnetic form factors of the neutron from Q2=1.75 to 4.00 (GeV/c)2.

Lung A, Stuart LM, Bosted PE, Andivahis L, Alster J, Arnold RG, Chang CC, Dietrich FS, Dodge WR, Gearhart R, Gomez J, Griffioen KA, Hicks RS, Hyde-Wright CE, Keppel C, Kuhn SE, Lichtenstadt J, Miskimen RA, Peterson GA, Petratos GG, Rock SE, Rokni SH, Sakumoto WK, Spengos M, Swartz K, Szalata Z, Tao LH
Phys Rev Lett. 1993;70(6):718-721 - PMID: 10054186

Determination of the neutron spin structure function.

Anthony PL, Arnold RG, Band HR, Borel H, Bosted PE, Breton V, Cates GD, Chupp TE, Dietrich FS, Dunne J, Erbacher R, Fellbaum J, Fonvieille H, Gearhart R, Holmes R, Hughes EW, Johnson JR, Kawall D, Keppel C, Kuhn SE, Lombard-Nelsen RM, Marroncle J, Maruyama T, Meyer W, Meziani Z, Middleton H, Morgenstern J, Newbury NR, Petratos GG, Pitthan R, Prepost R, Roblin Y, Rock SE, Rokni SH, Shapiro G, Smith T, Souder PA, Spengos M, Staley F, Stuart LM, Szalata ZM, Terrien Y, Thompson AK, White JL, Woo ...
Phys Rev Lett. 1993;71(7):959-962 - PMID: 10055413

Synergistic activation of transcription by Escherichia coli cAMP receptor protein.

Joung JK, Le LU, Hochschild A
Proc Natl Acad Sci U S A. 1993;90(7):3083-7 - PMID: 7681995 - PMCID: PMC46241

Thrombin receptor structure and function.

Coughlin SR, Scarborough RM, Vu TK, Hung DT
Cold Spring Harb Symp Quant Biol. 1993;57:149-54 - PMID: 1339654

Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location.

Bram RJ, Hung DT, Martin PK, Schreiber SL, Crabtree GR
Mol Cell Biol. 1993;13(8):4760-9 - PMID: 7687744 - PMCID: PMC360102

Activation of immune system effector function by T-cell or Fc receptor intracellular domains.

Romeo C, Kolanus W, Amiot M, Seed B
Cold Spring Harb Symp Quant Biol. 1993;57:117-25 - PMID: 1339650

Antiviral effects of different CD4-immunoglobulin constructs against HIV-1 and SIV: immunological characterization, pharmacokinetic data and in vivo experiments.

Langner KD, Niedrig M, Fultz P, Anderson D, Reiner G, Repke H, Gelderblom H, Seed B, Hilfenhaus J, Zettlmeissl G
Arch Virol. 1993;130(1-2):157-70 - PMID: 8503781

T cell activation by clustered tyrosine kinases.

Kolanus W, Romeo C, Seed B
Cell. 1993;74(1):171-83 - PMID: 8334702

What to do about high cholesterol

M Freeman, Consultant editor. PJ Skerret and SD Emond
President and Fellows of Harvard College. Harvard Health Publications. 1993;:ePub

Postmenopausal hormone-replacement therapy

Martin KA, and Freeman MW
New Engl J Med. 1993;328:1115-1117

Ascorbic acid oxidation product(s) protect human low density lipoprotein against atherogenic modification. Anti- rather than prooxidant activity of vitamin C in the presence of transition metal ions.

Retsky KL, Freeman MW, Frei B
J Biol Chem. 1993;268(2):1304-9 - PMID: 8419332

Postmenopausal hormone-replacement therapy.

Martin KA, Freeman MW
N Engl J Med. 1993;328(15):1115-7 - PMID: 8455670

Surface expression of human CD14 in Chinese hamster ovary fibroblasts imparts macrophage-like responsiveness to bacterial endotoxin.

Golenbock DT, Liu Y, Millham FH, Freeman MW, Zoeller RA
J Biol Chem. 1993;268(29):22055-9 - PMID: 7691822

Structures and high and low affinity ligand binding properties of murine type I and type II macrophage scavenger receptors.

Ashkenas J, Penman M, Vasile E, Acton S, Freeman M, Krieger M
J Lipid Res. 1993;34(6):983-1000 - PMID: 8394868

Characterization of cloned PTH/PTHrP receptors.

Segre GV, Abou-Samra AB, Jüppner H, Schipani E, Force T, Urena P, Freeman M, Kong XF, Kolakowski LF, Hock J
J Endocrinol Invest. 1993;15(9 Suppl 6):11-7 - PMID: 1338633

Cell signalling. A molecular growth industry.

Ruvkun G
Nature. 1993;360(6406):711-2 - PMID: 1334532

The Caenorhabditis elegans homeobox gene cluster.

Bürglin TR, Ruvkun G
Curr Opin Genet Dev. 1993;3(4):615-20 - PMID: 7902148

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans.

Wightman B, Ha I, Ruvkun G
Cell. 1993;75(5):855-62 - PMID: 8252622

A procedure for mapping Arabidopsis mutations using co-dominant ecotype-specific PCR-based markers.

Konieczny A, Ausubel FM
Plant J. 1993;4(2):403-10 - PMID: 8106085

Arabidopsis mutations at the RPS2 locus result in loss of resistance to Pseudomonas syringae strains expressing the avirulence gene avrRpt2.

Yu GL, Katagiri F, Ausubel FM
Mol Plant Microbe Interact. 1993;6(4):434-43 - PMID: 8400373

Dynamics of transcriptional and translational processes in hepatocytes cultured in a collagen sandwich.

Dunn JC, Tompkins RG, Yarmush ML
Biotechnol Bioeng. 1993;41(5):593-8 - PMID: 18609591

Optimization of hepatocyte attachment to microcarriers: Importance of oxygen.

Foy BD, Lee J, Morgan J, Toner M, Tompkins RG, Yarmush ML
Biotechnol Bioeng. 1993;42(5):579-88 - PMID: 18613079

LONG-TERM FUNCTIONAL RECOVERY OF HEPATOCYTES AFTER CRYOPRESERVATION IN A THREE-DIMENSIONAL CULTURE CONFIGURATION.

Borel Rinkes IH, Mehmet T, Sheehan SJ, Tompkins RG, Yarmush ML
Cell Transplant. 1992;1(4):281-292 - PMID: 28148377

Value of the history and stool occult blood test in selection of patients for upper endoscopy in Zimbabwe.

Xavier RJ, Stein CM, Kiire CF, Arrow J, Kitai I
East Afr Med J. 1992;69(5):268-71 - PMID: 1644046

Separation and quantitation of polyethylene glycols 400 and 3350 from human urine by high-performance liquid chromatography.

Ryan CM, Yarmush ML, Tompkins RG
J Pharm Sci. 1992;81(4):350-2 - PMID: 1501072

Fulminant hepatic failure treated with anti-endotoxin antibody.

Tompkins RG
Crit Care Med. 1992;20(11):1507 - PMID: 1424690

Antibody-targeted photolysis: in vitro immunological, photophysical, and cytotoxic properties of monoclonal antibody-dextran-Sn(IV) chlorin e6 immunoconjugates.

Rakestraw SL, Ford WE, Tompkins RG, Rodgers MA, Thorpe WP, Yarmush ML
Biotechnol Prog. 1992;8(1):30-9 - PMID: 1371392

Spatial distribution of tumor-specific monoclonal antibodies in human melanoma xenografts.

Shockley TR, Lin K, Nagy JA, Tompkins RG, Yarmush ML, Dvorak HF
Cancer Res. 1992;52(2):367-76 - PMID: 1728408

Hepatocytes in collagen sandwich: evidence for transcriptional and translational regulation.

Dunn JC, Tompkins RG, Yarmush ML
J Cell Biol. 1992;116(4):1043-53 - PMID: 1734019 - PMCID: PMC2289333

A quantitative analysis of tumor specific monoclonal antibody uptake by human melanoma xenografts: effects of antibody immunological properties and tumor antigen expression levels.

Shockley TR, Lin K, Sung C, Nagy JA, Tompkins RG, Dedrick RL, Dvorak HF, Yarmush ML
Cancer Res. 1992;52(2):357-66 - PMID: 1728407

Circulating interleukin-1 beta and tumor necrosis factor-alpha concentrations after burn injury in humans.

Cannon JG, Friedberg JS, Gelfand JA, Tompkins RG, Burke JF, Dinarello CA
Crit Care Med. 1992;20(10):1414-9 - PMID: 1395662

Increased transcellular permeability of rat small intestine after thermal injury.

Carter EA, Gonnella A, Tompkins RG
Burns. 1992;18(2):117-20 - PMID: 1590925

Hepatic tissue engineering. Development of critical technologies.

Yarmush ML, Toner M, Dunn JC, Rotem A, Hubel A, Tompkins RG
Ann N Y Acad Sci. 1992;665:238-52 - PMID: 1416606

Intracellular ice formation during the freezing of hepatocytes cultured in a double collagen gel.

Hubel A, Toner M, Cravalho EG, Yarmush ML, Tompkins RG
Biotechnol Prog. 1992;7(6):554-9 - PMID: 1367755

Sn-chlorin e6 antibacterial immunoconjugates. An in vitro and in vivo analysis.

Lu XM, Fischman AJ, Stevens E, Lee TT, Strong L, Tompkins RG, Yarmush ML
J Immunol Methods. 1992;156(1):85-99 - PMID: 1431166

Effects of dimethyl sulfoxide on cultured rat hepatocytes in sandwich configuration.

Borel Rinkes IH, Toner M, Ezzell RM, Tompkins RG, Yarmush ML
Cryobiology. 1992;29(4):443-53 - PMID: 1395682

Increased gut permeability early after burns correlates with the extent of burn injury.

Ryan CM, Yarmush ML, Burke JF, Tompkins RG
Crit Care Med. 1992;20(11):1508-12 - PMID: 1424691

A stable long-term hepatocyte culture system for studies of physiologic processes: cytokine stimulation of the acute phase response in rat and human hepatocytes.

Bader A, Borel Rinkes IH, Closs EI, Ryan CM, Toner M, Cunningham JM, Tompkins RG, Yarmush ML
Biotechnol Prog. 1992;8(3):219-25 - PMID: 1368259

Regulation of Flavonoid Biosynthetic Genes in Germinating Arabidopsis Seedlings.

Kubasek WL, Shirley BW, McKillop A, Goodman HM, Briggs W, Ausubel FM
Plant Cell. 1992;4(10):1229-1236 - PMID: 12297632 - PMCID: PMC160210

Large, identical, tandem repeating units in the C protein alpha antigen gene, bca, of group B streptococci.

Michel JL, Madoff LC, Olson K, Kling DE, Kasper DL, Ausubel FM
Proc Natl Acad Sci U S A. 1992;89(21):10060-4 - PMID: 1438195 - PMCID: PMC50277

The central domain of Rhizobium leguminosarum DctD functions independently to activate transcription.

Huala E, Stigter J, Ausubel FM
J Bacteriol. 1992;174(4):1428-31 - PMID: 1735730 - PMCID: PMC206444

Meiotic recombination on artificial chromosomes in yeast.

Ross LO, Treco D, Nicolas A, Szostak JW, Dawson D
Genetics. 1992;131(3):541-50 - PMID: 1385793 - PMCID: PMC1205028

A strategy for the generation of conditional mutations by protein destabilization.

Park EC, Finley D, Szostak JW
Proc Natl Acad Sci U S A. 1992;89(4):1249-52 - PMID: 1311090 - PMCID: PMC48426

In vitro genetics.

Szostak JW
Trends Biochem Sci. 1992;17(3):89-93 - PMID: 1384177

Selection of a ribozyme that functions as a superior template in a self-copying reaction.

Green R, Szostak JW
Science. 1992;258(5090):1910-5 - PMID: 1470913

Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures.

Ellington AD, Szostak JW
Nature. 1992;355(6363):850-2 - PMID: 1538766

ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity.

Park EC, Szostak JW
EMBO J. 1992;11(6):2087-93 - PMID: 1600941 - PMCID: PMC556675

Measurements of the electric and magnetic form factors of the proton from Q2=1.75 to 8.83 (GeV/c)2.

Bosted PE, Andivahis L, Lung A, Stuart LM, Alster J, Arnold RG, Chang CC, Dietrich FS, Dodge W, Gearhart R, Gomez J, Griffioen KA, Hicks RS, Hyde-Wright CE, Keppel C, Kuhn SE, Lichtenstadt J, Miskimen RA, Peterson GA, Petratos GG, Rock SE, Rokni S, Sakumoto WK, Spengos M, Swartz K, Szalata Z, Tao LH
Phys Rev Lett. 1992;68(26):3841-3844 - PMID: 10045818

Measurements of nu W2 and R= sigma L/ sigma T from inelastic electron-aluminum scattering near x=1.

Bosted PE, Lung A, Andivahis L, Stuart LM, Alster J, Arnold RG, Chang CC, Dietrich FS, Dodge W, Gearhart R, Gomez J, Griffioen KA, Hicks RS, Hyde-Wright CE, Keppel C, Kuhn SE, Lichtenstadt J, Miskimen RA, Peterson GA, Petratos GG, Rock SE, Rokni S, Sakumoto WK, Spengos M, Swartz K, Szalata Z, Tao LH
Phys Rev C Nucl Phys. 1992;46(6):2505-2515 - PMID: 9968381

Expression cloning and characterization of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation.

Coughlin SR, Vu TK, Hung DT, Wheaton VI
Semin Thromb Hemost. 1992;18(2):161-6 - PMID: 1321504

Thrombin-induced events in non-platelet cells are mediated by the unique proteolytic mechanism established for the cloned platelet thrombin receptor.

Hung DT, Vu TH, Nelken NA, Coughlin SR
J Cell Biol. 1992;116(3):827-32 - PMID: 1309820 - PMCID: PMC2289317

Characterization of a functional thrombin receptor. Issues and opportunities.

Coughlin SR, Vu TK, Hung DT, Wheaton VI
J Clin Invest. 1992;89(2):351-5 - PMID: 1310691 - PMCID: PMC442859

"Mirror image" antagonists of thrombin-induced platelet activation based on thrombin receptor structure.

Hung DT, Vu TK, Wheaton VI, Charo IF, Nelken NA, Esmon N, Esmon CT, Coughlin SR
J Clin Invest. 1992;89(2):444-50 - PMID: 1310695 - PMCID: PMC442871

Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation.

Hung DT, Vu TK, Wheaton VI, Ishii K, Coughlin SR
J Clin Invest. 1992;89(4):1350-3 - PMID: 1313452 - PMCID: PMC442997

HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides.

Garboczi DN, Hung DT, Wiley DC
Proc Natl Acad Sci U S A. 1992;89(8):3429-33 - PMID: 1565634 - PMCID: PMC48881

cDNA cloning of a human 25 kDa FK506 and rapamycin binding protein.

Hung DT, Schreiber SL
Biochem Biophys Res Commun. 1992;184(2):733-8 - PMID: 1374240

Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function.

Scarborough RM, Naughton MA, Teng W, Hung DT, Rose J, Vu TK, Wheaton VI, Turck CW, Coughlin SR
J Biol Chem. 1992;267(19):13146-9 - PMID: 1320011

The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase.

Hung DT, Wong YH, Vu TK, Coughlin SR
J Biol Chem. 1992;267(29):20831-4 - PMID: 1328213

Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells.

Simmons DL, Satterthwaite AB, Tenen DG, Seed B
J Immunol. 1992;148(1):267-71 - PMID: 1370171

Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease.

Dürkop H, Latza U, Hummel M, Eitelbach F, Seed B, Stein H
Cell. 1992;68(3):421-7 - PMID: 1310894

Sequence requirements for induction of cytolysis by the T cell antigen/Fc receptor zeta chain.

Romeo C, Amiot M, Seed B
Cell. 1992;68(5):889-97 - PMID: 1547489

Cloning and functional expression of the T cell activation antigen CD26.

Tanaka T, Camerini D, Seed B, Torimoto Y, Dang NH, Kameoka J, Dahlberg HN, Schlossman SF, Morimoto C
J Immunol. 1992;149(2):481-6 - PMID: 1352530

Marked by a mucin.

Seed B
Curr Biol. 1992;2(9):457-9 - PMID: 15335892

Lineage-independent activation of immune system effector function by myeloid Fc receptors.

Kolanus W, Romeo C, Seed B
EMBO J. 1992;11(13):4861-8 - PMID: 1464313 - PMCID: PMC556962

Rabbit aortic smooth muscle cells express inducible macrophage scavenger receptor messenger RNA that is absent from endothelial cells.

Bickel PE, Freeman MW
J Clin Invest. 1992;90(4):1450-7 - PMID: 1401078 - PMCID: PMC443191

Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium.

Abou-Samra AB, Jüppner H, Force T, Freeman MW, Kong XF, Schipani E, Urena P, Richards J, Bonventre JV, Potts JT
Proc Natl Acad Sci U S A. 1992;89(7):2732-6 - PMID: 1313566 - PMCID: PMC48736

Intron excision from tRNA precursors by plant splicing endonuclease requires unique features of the mature tRNA domain.

Stange N, Beier D, Beier H
Eur J Biochem. 1992;210(1):193-203 - PMID: 1332859

Dominant gain-of-function mutations that lead to misregulation of the C. elegans heterochronic gene lin-14, and the evolutionary implications of dominant mutations in pattern-formation genes.

Ruvkun G, Wightman B, Bürglin T, Arasu P
Dev Suppl. 1992;1:47-54 - PMID: 1742500

C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons.

Miller DM, Shen MM, Shamu CE, Bürglin TR, Ruvkun G, Dubois ML, Ghee M, Wilson L
Nature. 1992;355(6363):841-5 - PMID: 1347150

New motif in PBX genes.

Bürglin TR, Ruvkun G
Nat Genet. 1992;1(5):319-20 - PMID: 1363814

Regulation of the mec-3 gene by the C.elegans homeoproteins UNC-86 and MEC-3.

Xue D, Finney M, Ruvkun G, Chalfie M
EMBO J. 1992;11(13):4969-79 - PMID: 1361171 - PMCID: PMC556975

Cloning the Arabidopsis GA1 Locus by Genomic Subtraction.

Sun T, Goodman HM, Ausubel FM
Plant Cell. 1992;4(2):119-128 - PMID: 12297643 - PMCID: PMC160113

copia-like retrotransposons are ubiquitous among plants.

Voytas DF, Cummings MP, Koniczny A, Ausubel FM, Rodermel SR
Proc Natl Acad Sci U S A. 1992;89(15):7124-8 - PMID: 1379734 - PMCID: PMC49658

The importance of proline on long-term hepatocyte function in a collagen gel sandwich configuration: regulation of protein secretion.

Lee J, Morgan JR, Tompkins RG, Yarmush ML
Biotechnol Bioeng. 1992;40(2):298-305 - PMID: 18601116

Oxygen uptake rates in cultured rat hepatocytes.

Rotem A, Toner M, Tompkins RG, Yarmush ML
Biotechnol Bioeng. 1992;40(10):1286-91 - PMID: 18601082

Preparation and characterization of immunoconjugates for antibody-targeted photolysis.

Rakestraw SL, Tompkins RG, Yarmush ML
Bioconjug Chem. 1991;1(3):212-21 - PMID: 1710935

Penetration of tumor tissue by antibodies and other immunoproteins.

Shockley TR, Lin K, Nagy JA, Tompkins RG, Dvorak HF, Yarmush ML
Ann N Y Acad Sci. 1991;618:367-82 - PMID: 2006796

Cryopreservation of isolated hepatocytes: intracellular ice formation under various chemical and physical conditions.

Harris CL, Toner M, Hubel A, Cravalho EG, Yarmush ML, Tompkins RG
Cryobiology. 1991;28(5):436-44 - PMID: 1752131

Antibody-targeted photolysis. Bacteriocidal effects of Sn (IV) chlorin e6-dextran-monoclonal antibody conjugates.

Friedberg JS, Tompkins RG, Rakestraw SL, Warren SW, Fischman AJ, Yarmush ML
Ann N Y Acad Sci. 1991;618:383-93 - PMID: 1706578

Imaging infections with antibodies. A method to localize occult infections.

Tompkins RG, Fischman AJ, Yarmush ML
Chest. 1991;100(3 Suppl):169S-172S - PMID: 1909225

Progress in burn treatment and the use of artificial skin.

Tompkins RG, Burke JF
World J Surg. 1991;14(6):819-24 - PMID: 2256353

Quantitative analysis of blood vessel permeability of squirrel monkeys.

Tompkins RG
Am J Physiol. 1991;260(4 Pt 2):H1194-204 - PMID: 2012223

Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration.

Dunn JC, Tompkins RG, Yarmush ML
Biotechnol Prog. 1991;7(3):237-45 - PMID: 1367596

A superfamily of Arabidopsis thaliana retrotransposons.

Konieczny A, Voytas DF, Cummings MP, Ausubel FM
Genetics. 1991;127(4):801-9 - PMID: 1709409 - PMCID: PMC1204407

The centromere region of Arabidopsis thaliana chromosome 1 contains telomere-similar sequences.

Richards EJ, Goodman HM, Ausubel FM
Nucleic Acids Res. 1991;19(12):3351-7 - PMID: 1648204 - PMCID: PMC328334

Aerobic inactivation of Rhizobium meliloti NifA in Escherichia coli is mediated by lon and two newly identified genes, snoB and snoC.

Huala E, Moon AL, Ausubel FM
J Bacteriol. 1991;173(1):382-90 - PMID: 1846139 - PMCID: PMC207197

Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack.

Keith B, Dong XN, Ausubel FM, Fink GR
Proc Natl Acad Sci U S A. 1991;88(19):8821-5 - PMID: 1681544 - PMCID: PMC52602

High intensity and blue light regulated expression of chimeric chalcone synthase genes in transgenic Arabidopsis thaliana plants.

Feinbaum RL, Storz G, Ausubel FM
Mol Gen Genet. 1991;226(3):449-56 - PMID: 2038307

Nodules elicited by Rhizobium meliloti heme mutants are arrested at an early stage of development.

Dickstein R, Scheirer DC, Fowle WH, Ausubel FM
Mol Gen Genet. 1991;230(3):423-32 - PMID: 1766439

Cloned alpha and beta C-protein antigens of group B streptococci elicit protective immunity.

Michel JL, Madoff LC, Kling DE, Kasper DL, Ausubel FM
Infect Immun. 1991;59(6):2023-8 - PMID: 1674738 - PMCID: PMC257960

Template-directed primer extension catalyzed by the Tetrahymena ribozyme.

Bartel DP, Doudna JA, Usman N, Szostak JW
Mol Cell Biol. 1991;11(6):3390-4 - PMID: 2038341 - PMCID: PMC360195

A multisubunit ribozyme that is a catalyst of and template for complementary strand RNA synthesis.

Doudna JA, Couture S, Szostak JW
Science. 1991;251(5001):1605-8 - PMID: 1707185

Mutations in a semiconserved region of the Tetrahymena intron.

Pace U, Szostak JW
FEBS Lett. 1991;280(1):171-4 - PMID: 2009960

Synthesis of RNA containing inosine: analysis of the sequence requirements for the 5' splice site of the Tetrahymena group I intron.

Green R, Szostak JW, Benner SA, Rich A, Usman N
Nucleic Acids Res. 1991;19(15):4161-6 - PMID: 1714564 - PMCID: PMC328556

Genetic and physical analyses of sister chromatid exchange in yeast meiosis.

Sun H, Dawson D, Szostak JW
Mol Cell Biol. 1991;11(12):6328-36 - PMID: 1944292 - PMCID: PMC361828

HIV-1 Rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA.

Bartel DP, Zapp ML, Green MR, Szostak JW
Cell. 1991;67(3):529-36 - PMID: 1934059

A poly(dA.dT) tract is a component of the recombination initiation site at the ARG4 locus in Saccharomyces cerevisiae.

Schultes NP, Szostak JW
Mol Cell Biol. 1991;11(1):322-8 - PMID: 1986228 - PMCID: PMC359622

Extensive 3'-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation site.

Sun H, Treco D, Szostak JW
Cell. 1991;64(6):1155-61 - PMID: 2004421

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation.

Vu TK, Hung DT, Wheaton VI, Coughlin SR
Cell. 1991;64(6):1057-68 - PMID: 1672265

Domains specifying thrombin-receptor interaction.

Vu TK, Wheaton VI, Hung DT, Charo I, Coughlin SR
Nature. 1991;353(6345):674-7 - PMID: 1717851

The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells.

Stamenkovic I, Aruffo A, Amiot M, Seed B
EMBO J. 1991;10(2):343-8 - PMID: 1991450 - PMCID: PMC452652

Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides.

Romeo C, Seed B
Cell. 1991;64(5):1037-46 - PMID: 1900456

The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins.

Aruffo A, Melnick MB, Linsley PS, Seed B
J Exp Med. 1991;174(4):949-52 - PMID: 1919444 - PMCID: PMC2118957

CD62/P-selectin recognition of myeloid and tumor cell sulfatides.

Aruffo A, Kolanus W, Walz G, Fredman P, Seed B
Cell. 1991;67(1):35-44 - PMID: 1717159

The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family.

Camerini D, Walz G, Loenen WA, Borst J, Seed B
J Immunol. 1991;147(9):3165-9 - PMID: 1655907

A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide.

Jüppner H, Abou-Samra AB, Freeman M, Kong XF, Schipani E, Richards J, Kolakowski LF, Hock J, Potts JT, Kronenberg HM
Science. 1991;254(5034):1024-6 - PMID: 1658941

Expression of type I and type II bovine scavenger receptors in Chinese hamster ovary cells: lipid droplet accumulation and nonreciprocal cross competition by acetylated and oxidized low density lipoprotein.

Freeman M, Ekkel Y, Rohrer L, Penman M, Freedman NJ, Chisolm GM, Krieger M
Proc Natl Acad Sci U S A. 1991;88(11):4931-5 - PMID: 2052575 - PMCID: PMC51781

Nuclear tRNA(Tyr) genes are highly amplified at a single chromosomal site in the genome of Arabidopsis thaliana.

Beier D, Stange N, Gross HJ, Beier H
Mol Gen Genet. 1991;225(1):72-80 - PMID: 2000093

Expression of nuclear tRNA(Tyr) genes from Arabidopsis thaliana in HeLa cell and wheat germ extracts.

Stange N, Beier D, Beier H
Plant Mol Biol. 1991;16(5):865-75 - PMID: 1859869

Regulation of transcription and cell identity by POU domain proteins.

Ruvkun G, Finney M
Cell. 1991;64(3):475-8 - PMID: 1991317

Nematode homeobox cluster.

Bürglin TR, Ruvkun G, Coulson A, Hawkins NC, McGhee JD, Schaller D, Wittmann C, Müller F, Waterston RH
Nature. 1991;351(6329):703 - PMID: 1676487

Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development.

Wightman B, Bürglin TR, Gatto J, Arasu P, Ruvkun G
Genes Dev. 1991;5(10):1813-24 - PMID: 1916264

Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28.

Arasu P, Wightman B, Ruvkun G
Genes Dev. 1991;5(10):1825-33 - PMID: 1916265

Induction of Arabidopsis defense genes by virulent and avirulent Pseudomonas syringae strains and by a cloned avirulence gene.

Dong X, Mindrinos M, Davis KR, Ausubel FM
Plant Cell. 1991;3(1):61-72 - PMID: 1824335 - PMCID: PMC159979

Antibody-targeted photolysis: in vitro studies with Sn(IV) chlorin e6 covalently bound to monoclonal antibodies using a modified dextran carrier.

Rakestraw SL, Tompkins RG, Yarmush ML
Proc Natl Acad Sci U S A. 1990;87(11):4217-21 - PMID: 1693435 - PMCID: PMC54079

Injury-induced inhibition of small intestinal protein and nucleic acid synthesis.

Carter EA, Hatz RA, Yarmush ML, Tompkins RG
Gastroenterology. 1990;98(6):1445-51 - PMID: 1692545

Cutaneous thermal injury alters macromolecular permeability of rat small intestine.

Carter EA, Tompkins RG, Schiffrin E, Burke JF
Surgery. 1990;107(3):335-41 - PMID: 2309150

Imaging infections with antibodies. A quantitative autoradiographic analysis.

Morrel EM, Tompkins RG, Fischman AJ, Wilkinson RA, Yarmush ML
J Immunol Methods. 1990;130(1):39-48 - PMID: 2193059

A new approach to the cryopreservation of hepatocytes in a sandwich culture configuration.

Koebe HG, Dunn JC, Toner M, Sterling LM, Hubel A, Cravalho EG, Yarmush ML, Tompkins RG
Cryobiology. 1990;27(5):576-84 - PMID: 2249459

Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever.

Cannon JG, Tompkins RG, Gelfand JA, Michie HR, Stanford GG, van der Meer JW, Endres S, Lonnemann G, Corsetti J, Chernow B
J Infect Dis. 1990;161(1):79-84 - PMID: 2295861

Equilibrium binding characteristics of monoclonal antibodies recognizing melanoma cell surface antigens.

Shockley TR, Mandeville JT, Tompkins RG, Yarmush ML
Hybridoma. 1990;9(6):527-44 - PMID: 2076895

Prokaryotic signal transduction mediated by sensor and regulator protein pairs.

Albright LM, Huala E, Ausubel FM
Annu Rev Genet. 1990;23:311-36 - PMID: 2694934

Rhizobium meliloti nodD genes mediate host-specific activation of nodABC.

Honma MA, Asomaning M, Ausubel FM
J Bacteriol. 1990;172(2):901-11 - PMID: 2298703 - PMCID: PMC208518

Detection of heteroduplex DNA molecules among the products of Saccharomyces cerevisiae meiosis.

Lichten M, Goyon C, Schultes NP, Treco D, Szostak JW, Haber JE, Nicolas A
Proc Natl Acad Sci U S A. 1990;87(19):7653-7 - PMID: 2217196 - PMCID: PMC54806

Phylogenetic and genetic evidence for base-triples in the catalytic domain of group I introns.

Michel F, Ellington AD, Couture S, Szostak JW
Nature. 1990;347(6293):578-80 - PMID: 2215683

Decreasing gradients of gene conversion on both sides of the initiation site for meiotic recombination at the ARG4 locus in yeast.

Schultes NP, Szostak JW
Genetics. 1990;126(4):813-22 - PMID: 1981763 - PMCID: PMC1204280

Mutational analysis of conserved nucleotides in a self-splicing group I intron.

Couture S, Ellington AD, Gerber AS, Cherry JM, Doudna JA, Green R, Hanna M, Pace U, Rajagopal J, Szostak JW
J Mol Biol. 1990;215(3):345-58 - PMID: 1700131

In vitro selection of RNA molecules that bind specific ligands.

Ellington AD, Szostak JW
Nature. 1990;346(6287):818-22 - PMID: 1697402

In vitro genetic analysis of the Tetrahymena self-splicing intron.

Green R, Ellington AD, Szostak JW
Nature. 1990;347(6291):406-8 - PMID: 2215650

Chemical synthesis of oligoribonucleotides containing 2-aminopurine: substrates for the investigation of ribozyme function.

Doudna JA, Szostak JW, Rich A, Usman N
J Org Chem. 1990;55(21):5547-9 - PMID: 11540922

Saccharomyces cerevisiae homoserine kinase is homologous to prokaryotic homoserine kinases.

Schultes NP, Ellington AD, Cherry JM, Szostak JW
Gene. 1990;96(2):177-80 - PMID: 2176637

Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML.

Park EC, Szostak JW
Mol Cell Biol. 1990;10(9):4932-4 - PMID: 2117703 - PMCID: PMC361112

Electrolyte gradient gels for DNA sequencing.

Sheen JY, Seed B
Biotechniques. 1990;6(10):942-4 - PMID: 3273397

A CD4 domain important for HIV-mediated syncytium formation lies outside the virus binding site.

Camerini D, Seed B
Cell. 1990;60(5):747-54 - PMID: 2107024

Improved genetic selection for screening bacteriophage libraries by homologous recombination in vivo.

Kurnit DM, Seed B
Proc Natl Acad Sci U S A. 1990;87(8):3166-9 - PMID: 2183225 - PMCID: PMC53855

The B-cell antigen CD22 mediates monocyte and erythrocyte adhesion.

Stamenkovic I, Seed B
Nature. 1990;345(6270):74-7 - PMID: 1691828

Expression and characterization of human CD4:immunoglobulin fusion proteins.

Zettlmeissl G, Gregersen JP, Duport JM, Mehdi S, Reiner G, Seed B
DNA Cell Biol. 1990;9(5):347-53 - PMID: 2196903

CD44 is the principal cell surface receptor for hyaluronate.

Aruffo A, Stamenkovic I, Melnick M, Underhill CB, Seed B
Cell. 1990;61(7):1303-13 - PMID: 1694723

Identification of the intracytoplasmic region essential for signal transduction through a B cell activation molecule, CD40.

Inui S, Kaisho T, Kikutani H, Stamenkovic I, Seed B, Clark EA, Kishimoto T
Eur J Immunol. 1990;20(8):1747-53 - PMID: 1698631

Expression of the CD6 T lymphocyte differentiation antigen in normal human brain.

Mayer B, Funke I, Seed B, Riethmüller G, Weiss E
J Neuroimmunol. 1990;29(1-3):193-202 - PMID: 2211985

The primary structure of the human leukocyte antigen CD37, a species homologue of the rat MRC OX-44 antigen.

Classon BJ, Williams AF, Willis AC, Seed B, Stamenkovic I
J Exp Med. 1990;172(3):1007 - PMID: 2388030 - PMCID: PMC2188538

Recognition by ELAM-1 of the sialyl-Lex determinant on myeloid and tumor cells.

Walz G, Aruffo A, Kolanus W, Bevilacqua M, Seed B
Science. 1990;250(4984):1132-5 - PMID: 1701275

Thymosin beta 4 is expressed in ROS 17/2.8 osteosarcoma cells in a regulated manner.

Atkinson MJ, Freeman MW, Kronenberg HM
Mol Endocrinol. 1990;4(1):69-74 - PMID: 2325669

An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors.

Freeman M, Ashkenas J, Rees DJ, Kingsley DM, Copeland NG, Jenkins NA, Krieger M
Proc Natl Acad Sci U S A. 1990;87(22):8810-4 - PMID: 1978939 - PMCID: PMC55049

Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II.

Rohrer L, Freeman M, Kodama T, Penman M, Krieger M
Nature. 1990;343(6258):570-2 - PMID: 2300208

Type I macrophage scavenger receptor contains alpha-helical and collagen-like coiled coils.

Kodama T, Freeman M, Rohrer L, Zabrecky J, Matsudaira P, Krieger M
Nature. 1990;343(6258):531-5 - PMID: 2300204

Detection of mutations and DNA polymorphisms using whole genome Southern Cross hybridization.

Ruvkun G, Gilbert W, Horvitz HR
Nucleic Acids Res. 1990;18(4):809-15 - PMID: 2315039 - PMCID: PMC330331

The unc-86 gene product couples cell lineage and cell identity in C. elegans.

Finney M, Ruvkun G
Cell. 1990;63(5):895-905 - PMID: 2257628

Genomic subtraction for cloning DNA corresponding to deletion mutations.

Straus D, Ausubel FM
Proc Natl Acad Sci U S A. 1990;87(5):1889-93 - PMID: 2408039 - PMCID: PMC53589

The structure, distribution and evolution of the Ta1 retrotransposable element family of Arabidopsis thaliana.

Voytas DF, Konieczny A, Cummings MP, Ausubel FM
Genetics. 1990;126(3):713-21 - PMID: 2174394 - PMCID: PMC1204225

Low-density lipoprotein transport in blood vessel walls of squirrel monkeys.

Tompkins RG, Yarmush ML, Schnitzer JJ, Colton CK, Smith KA, Stemerman MB
Am J Physiol. 1989;257(2 Pt 2):H452-64 - PMID: 2764130

Increased survival after massive thermal injuries in adults: preliminary report using artificial skin.

Tompkins RG, Hilton JF, Burke JF, Schoenfeld DA, Hegarty MT, Bondoc CC, Quinby WC, Behringer GE, Ackroyd FW
Crit Care Med. 1989;17(8):734-40 - PMID: 2546715

Inhibition of in vivo DNA synthesis in regenerating rat liver following thermal injury.

Carter EA, Kirkham SE, Tompkins RG, Burke JF
Biochem Biophys Res Commun. 1989;160(1):196-201 - PMID: 2785385

Hepatic and intestinal blood flow following thermal injury.

Carter EA, Tompkins RG, Burke JF
J Burn Care Rehabil. 1989;9(4):347-50 - PMID: 3220848

Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration.

Dunn JC, Yarmush ML, Koebe HG, Tompkins RG
FASEB J. 1989;3(2):174-7 - PMID: 2914628

Autoradiographic method for quantitation of radiolabeled proteins in tissues using indium-111.

Morrell EM, Tompkins RG, Fischman AJ, Wilkinson RA, Burke JF, Rubin RH, Strauss HW, Yarmush ML
J Nucl Med. 1989;30(9):1538-45 - PMID: 2504892

Macromolecular transport within heart valves.

Tompkins RG, Schnitzer JJ, Yarmush ML
Circ Res. 1989;64(6):1213-23 - PMID: 2720921

Occult gastrointestinal bleeding: newer techniques and diagnosis and therapy.

Moncure AC, Tompkins RG, Athanasoulis CA, Welch CE
Adv Surg. 1989;22:141-77 - PMID: 2645744

A dual-labeling method for identifying differentially expressed genes: use in the identification of cDNA clones that hybridize to RNAs whose abundance in tomato flowers is potentially regulated by gibberellins.

Olszewski NE, Gast RT, Ausubel FM
Gene. 1989;77(1):155-62 - PMID: 2663653

Identification of a gene linked to Rhizobium meliloti ntrA whose product is homologous to a family to ATP-binding proteins.

Albright LM, Ronson CW, Nixon BT, Ausubel FM
J Bacteriol. 1989;171(4):1932-41 - PMID: 2703463 - PMCID: PMC209842

The central domain of Rhizobium meliloti NifA is sufficient to activate transcription from the R. meliloti nifH promoter.

Huala E, Ausubel FM
J Bacteriol. 1989;171(6):3354-65 - PMID: 2722751 - PMCID: PMC210058

General method for site-directed mutagenesis in Escherichia coli O18ac:K1:H7: deletion of the inducible superoxide dismutase gene, sodA, does not diminish bacteremia in neonatal rats.

Bloch CA, Thorne GM, Ausubel FM
Infect Immun. 1989;57(7):2141-8 - PMID: 2543632 - PMCID: PMC313853

Rhizobium meliloti 1021 has three differentially regulated loci involved in glutamine biosynthesis, none of which is essential for symbiotic nitrogen fixation.

de Bruijn FJ, Rossbach S, Schneider M, Ratet P, Messmer S, Szeto WW, Ausubel FM, Schell J
J Bacteriol. 1989;171(3):1673-82 - PMID: 2563998 - PMCID: PMC209797

The guanosine binding site of the Tetrahymena ribozyme.

Michel F, Hanna M, Green R, Bartel DP, Szostak JW
Nature. 1989;342(6248):391-5 - PMID: 2685606

Double-strand breaks at an initiation site for meiotic gene conversion.

Sun H, Treco D, Schultes NP, Szostak JW
Nature. 1989;338(6210):87-90 - PMID: 2645528

An initiation site for meiotic gene conversion in the yeast Saccharomyces cerevisiae.

Nicolas A, Treco D, Schultes NP, Szostak JW
Nature. 1989;338(6210):35-9 - PMID: 2537472

Telomerase: the beginning of the ends.

Szostak JW
Nature. 1989;337(6205):303-4 - PMID: 2765013

Miniribozymes, small derivatives of the sunY intron, are catalytically active.

Doudna JA, Szostak JW
Mol Cell Biol. 1989;9(12):5480-3 - PMID: 2685567 - PMCID: PMC363717

RNA structure, not sequence, determines the 5' splice-site specificity of a group I intron.

Doudna JA, Cormack BP, Szostak JW
Proc Natl Acad Sci U S A. 1989;86(19):7402-6 - PMID: 2678103 - PMCID: PMC298070

Stereochemical course of catalysis by the Tetrahymena ribozyme.

Rajagopal J, Doudna JA, Szostak JW
Science. 1989;244(4905):692-4 - PMID: 2470151

A mutant with a defect in telomere elongation leads to senescence in yeast.

Lundblad V, Szostak JW
Cell. 1989;57(4):633-43 - PMID: 2655926

RNA-catalysed synthesis of complementary-strand RNA.

Doudna JA, Szostak JW
Nature. 1989;339(6225):519-22 - PMID: 2660003

Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins.

Bevilacqua MP, Stengelin S, Gimbrone MA, Seed B
Science. 1989;243(4895):1160-5 - PMID: 2466335

A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.

Stamenkovic I, Clark EA, Seed B
EMBO J. 1989;8(5):1403-10 - PMID: 2475341 - PMCID: PMC400967

A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family.

Stamenkovic I, Amiot M, Pesando JM, Seed B
Cell. 1989;56(6):1057-62 - PMID: 2466575

CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes.

Oquendo P, Hundt E, Lawler J, Seed B
Cell. 1989;58(1):95-101 - PMID: 2473841

Improved suppressor tRNA cloning vectors and plasmid-phage recombination.

Huang HV, Little PF, Seed B
Biotechnology. 1989;10:269-83 - PMID: 3061517

Isolation and expression of functional high-affinity Fc receptor complementary DNAs.

Allen JM, Seed B
Science. 1989;243(4889):378-81 - PMID: 2911749

The primary structure of the human leukocyte antigen CD37, a species homologue of the rat MRC OX-44 antigen.

Classon BJ, Williams AF, Willis AC, Seed B, Stamenkovic I
J Exp Med. 1989;169(4):1497-502 - PMID: 2466944 - PMCID: PMC2189247

Monocyte antigen CD14 is a phospholipid anchored membrane protein.

Simmons DL, Tan S, Tenen DG, Nicholson-Weller A, Seed B
Blood. 1989;73(1):284-9 - PMID: 2462937

Expression of cDNA clones encoding the thymocyte antigens CD1a, b, c demonstrates a hierarchy of exclusion in fibroblasts.

Aruffo A, Seed B
J Immunol. 1989;143(5):1723-30 - PMID: 2701945

A human macrophage-associated antigen (CD68) detected by six different monoclonal antibodies.

Micklem K, Rigney E, Cordell J, Simmons D, Stross P, Turley H, Seed B, Mason D
Br J Haematol. 1989;73(1):6-11 - PMID: 2803980

Leu-8/TQ1 is the human equivalent of the Mel-14 lymph node homing receptor.

Camerini D, James SP, Stamenkovic I, Seed B
Nature. 1989;342(6245):78-82 - PMID: 2509939

Risk factors in coronary artery disease and cardiac rehabilitation. In: Haber E, Eagle KA, Austen WG, eds

Freeman MW, Rigotti NA, and T. Force
The Practice of Cardiology. 1989;:563-614

Mutations in signal sequence cleavage domain of preproparathyroid hormone alter protein translocation, signal sequence cleavage, and membrane-binding properties.

Wiren KM, Ivashkiv L, Ma P, Freeman MW, Potts JT, Kronenberg HM
Mol Endocrinol. 1989;3(2):240-50 - PMID: 2710131

Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14.

Ruvkun G, Ambros V, Coulson A, Waterston R, Sulston J, Horvitz HR
Genetics. 1989;121(3):501-16 - PMID: 2565854 - PMCID: PMC1203636

The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch.

Ruvkun G, Giusto J
Nature. 1989;338(6213):313-9 - PMID: 2922060

Caenorhabditis elegans has scores of homoeobox-containing genes.

Bürglin TR, Finney M, Coulson A, Ruvkun G
Nature. 1989;341(6239):239-43 - PMID: 2571091

Arabidopsis thaliana mutant that develops as a light-grown plant in the absence of light.

Chory J, Peto C, Feinbaum R, Pratt L, Ausubel F
Cell. 1989;58(5):991-9 - PMID: 2776216

Redistribution of blood flow after thermal injury and hemorrhagic shock.

Carter EA, Tompkins RG, Yarmush ML, Walker WA, Burke JF
J Appl Physiol. 1988;65(4):1782-8 - PMID: 3182540

Increase of sialyltransferase activity in the small intestine following thermal injury in rats.

Ch SW, Carter EA, Tompkins RG, Burke JF
Biochem Biophys Res Commun. 1988;153(1):377-81 - PMID: 3259879

Rectal necrosis after pelvic crush injury.

Tompkins RG, McCabe CJ, Burke JF, Keating MA, Wright CD
J Trauma. 1988;28(5):697-9 - PMID: 3367418

Significant reductions in mortality for children with burn injuries through the use of prompt eschar excision.

Tompkins RG, Remensnyder JP, Burke JF, Tompkins DM, Hilton JF, Schoenfeld DA, Behringer GE, Bondoc CC, Briggs SE, Quinby WC
Ann Surg. 1988;208(5):577-85 - PMID: 3190284 - PMCID: PMC1493782

Measurement of 125I-low density lipoprotein uptake in selected tissues of the squirrel monkey by quantitative autoradiography.

Tompkins RG, Schnitzer JJ, Yarmush ML, Colton CK, Smith KA
Am J Pathol. 1988;132(3):526-42 - PMID: 3414782 - PMCID: PMC1880767

Interference between Rhizobium meliloti and Rhizobium trifolii nodulation genes: genetic basis of R. meliloti dominance.

Debellé F, Maillet F, Vasse J, Rosenberg C, de Billy F, Truchet G, Dénarié J, Ausubel FM
J Bacteriol. 1988;170(12):5718-27 - PMID: 2848012 - PMCID: PMC211674

Specialized binary vector for plant transformation: expression of the Arabidopsis thaliana AHAS gene in Nicotiana tabacum.

Olszewski NE, Martin FB, Ausubel FM
Nucleic Acids Res. 1988;16(22):10765-82 - PMID: 3060849 - PMCID: PMC338938

Developmental regulation of nodule-specific genes in alfalfa root nodules.

Dunn K, Dickstein R, Feinbaum R, Burnett BK, Peterman TK, Thoidis G, Goodman HM, Ausubel FM
Mol Plant Microbe Interact. 1988;1(2):66-74 - PMID: 2908768

Expression of nodule-specific genes in alfalfa root nodules blocked at an early stage of development.

Dickstein R, Bisseling T, Reinhold VN, Ausubel FM
Genes Dev. 1988;2(6):677-87 - PMID: 3417147

Transcriptional regulation of the Arabidopsis thaliana chalcone synthase gene.

Feinbaum RL, Ausubel FM
Mol Cell Biol. 1988;8(5):1985-92 - PMID: 3386631 - PMCID: PMC363377

Genetic dissection of an RNA enzyme.

Doudna JA, Gerber AS, Cherry JM, Szostak JW
Cold Spring Harb Symp Quant Biol. 1988;52:173-80 - PMID: 2456876

Gene conversion adjacent to regions of double-strand break repair.

Orr-Weaver TL, Nicolas A, Szostak JW
Mol Cell Biol. 1988;8(12):5292-8 - PMID: 3072478 - PMCID: PMC365631

Telomeric repeat from T. thermophila cross hybridizes with human telomeres.

Allshire RC, Gosden JR, Cross SH, Cranston G, Rout D, Sugawara N, Szostak JW, Fantes PA, Hastie ND
Nature. 1988;332(6165):656-9 - PMID: 2833706

Characterization of two telomeric DNA processing reactions in Saccharomyces cerevisiae.

Murray AW, Claus TE, Szostak JW
Mol Cell Biol. 1988;8(11):4642-50 - PMID: 3062364 - PMCID: PMC365553

A simple phase-extraction assay for chloramphenicol acyltransferase activity.

Seed B, Sheen JY
Gene. 1988;67(2):271-7 - PMID: 3169576

Functional analysis of CD2, CD4, and CD8 in T-cell activation.

Bierer BE, Greenstein JL, Sleckman B, Ratnofsky S, Peterson A, Seed B, Burakoff SJ
Ann N Y Acad Sci. 1988;532:199-206 - PMID: 3052208

Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III integral membrane protein.

Stamenkovic I, Seed B
J Exp Med. 1988;167(6):1975-80 - PMID: 3260267 - PMCID: PMC2189672

Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation.

Bierer BE, Peterson A, Barbosa J, Seed B, Burakoff SJ
Proc Natl Acad Sci U S A. 1988;85(4):1194-8 - PMID: 2448792 - PMCID: PMC279733

Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4.

Peterson A, Seed B
Cell. 1988;54(1):65-72 - PMID: 2454749

The Fc gamma receptor of natural killer cells is a phospholipid-linked membrane protein.

Simmons D, Seed B
Nature. 1988;333(6173):568-70 - PMID: 2967436

Isolation of cDNAs of scrapie-modulated RNAs by subtractive hybridization of a cDNA library.

Duguid JR, Rohwer RG, Seed B
Proc Natl Acad Sci U S A. 1988;85(15):5738-42 - PMID: 2456582 - PMCID: PMC281836

CD19, the earliest differentiation antigen of the B cell lineage, bears three extracellular immunoglobulin-like domains and an Epstein-Barr virus-related cytoplasmic tail.

Stamenkovic I, Seed B
J Exp Med. 1988;168(3):1205-10 - PMID: 2459292 - PMCID: PMC2189043

Isolation of cDNAs for two distinct human Fc receptors by ligand affinity cloning.

Stengelin S, Stamenkovic I, Seed B
EMBO J. 1988;7(4):1053-9 - PMID: 3402431 - PMCID: PMC454434

Nucleotide sequence of three cDNAs for the human high affinity Fc receptor (FcRI).

Allen JM, Seed B
Nucleic Acids Res. 1988;16(24):11824 - PMID: 2974947 - PMCID: PMC339124

Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells.

Simmons D, Seed B
J Immunol. 1988;141(8):2797-800 - PMID: 3139766

ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM.

Simmons D, Makgoba MW, Seed B
Nature. 1988;331(6157):624-7 - PMID: 3340213

Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor.

Yamasaki K, Taga T, Hirata Y, Yawata H, Kawanishi Y, Seed B, Taniguchi T, Hirano T, Kishimoto T
Science. 1988;241(4867):825-8 - PMID: 3136546

Central nervous system lesions in pediatric patients: Gd-DTPA-enhanced MR imaging.

Powers TA, Partain CL, Kessler RM, Freeman MW, Robertson RH, Wyatt SH, Whelan HT
Radiology. 1988;169(3):723-6 - PMID: 3055036

Wheat germ splicing endonuclease is highly specific for plant pre-tRNAs.

Stange N, Gross HJ, Beier H
EMBO J. 1988;7(12):3823-8 - PMID: 3208752 - PMCID: PMC454960

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.

Herr W, Sturm RA, Clerc RG, Corcoran LM, Baltimore D, Sharp PA, Ingraham HA, Rosenfeld MG, Finney M, Ruvkun G
Genes Dev. 1988;2(12A):1513-6 - PMID: 3215510

The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors.

Finney M, Ruvkun G, Horvitz HR
Cell. 1988;55(5):757-69 - PMID: 2903797

Isolation of a higher eukaryotic telomere from Arabidopsis thaliana.

Richards EJ, Ausubel FM
Cell. 1988;53(1):127-36 - PMID: 3349525

A copia-like transposable element family in Arabidopsis thaliana.

Voytas DF, Ausubel FM
Nature. 1988;336(6196):242-4 - PMID: 2904123

Differential Expression in Bundle Sheath and Mesophyll Cells of Maize of Genes for Photosystem II Components Encoded by the Plastid Genome.

Sheen JY, Bogorad L
Plant Physiol. 1988;86(4):1020-6 - PMID: 16666025 - PMCID: PMC1054621

Enzymatic function of alginate immobilized rat hepatocytes.

Tompkins RG, Carter EA, Carlson JD, Yarmush ML
Biotechnol Bioeng. 1988;31(1):11-8 - PMID: 18581557

Regulation of levels of nuclear transcripts for C4 photosynthesis in bundle sheath and mesophyll cells of maize leaves.

Sheen JY, Bogorad L
Plant Mol Biol. 1987;8(3):227-38 - PMID: 24301127

Differential expression of oxygen-evolving polypeptide genes in maize leaf cell types.

Sheen JY, Sayre RT, Bogorad L
Plant Mol Biol. 1987;9(3):217-26 - PMID: 24276970

Rhizobium meliloti ntrA (rpoN) gene is required for diverse metabolic functions.

Ronson CW, Nixon BT, Albright LM, Ausubel FM
J Bacteriol. 1987;169(6):2424-31 - PMID: 3034856 - PMCID: PMC212082

Identification and characterization of the Rhizobium meliloti ntrC gene: R. meliloti has separate regulatory pathways for activation of nitrogen fixation genes in free-living and symbiotic cells.

Szeto WW, Nixon BT, Ronson CW, Ausubel FM
J Bacteriol. 1987;169(4):1423-32 - PMID: 2881918 - PMCID: PMC211963

Conservation of structure and location of Rhizobium meliloti and Klebsiella pneumoniae nifB genes.

Buikema WJ, Klingensmith JA, Gibbons SL, Ausubel FM
J Bacteriol. 1987;169(3):1120-6 - PMID: 3029020 - PMCID: PMC211909

Isolation and characterization of symbiotic mutants of bradyrhizobium sp. (Arachis) strain NC92: mutants with host-specific defects in nodulation and nitrogen fixation.

Wilson KJ, Anjaiah V, Nambiar PT, Ausubel FM
J Bacteriol. 1987;169(5):2177-86 - PMID: 3032910 - PMCID: PMC212124

Regulation of nitrogen fixation genes.

Gussin GN, Ronson CW, Ausubel FM
Annu Rev Genet. 1987;20:567-91 - PMID: 3545064

Genetic and structural analysis of the Rhizobium meliloti fixA, fixB, fixC, and fixX genes.

Earl CD, Ronson CW, Ausubel FM
J Bacteriol. 1987;169(3):1127-36 - PMID: 3029021 - PMCID: PMC211910

Deduced products of C4-dicarboxylate transport regulatory genes of Rhizobium leguminosarum are homologous to nitrogen regulatory gene products.

Ronson CW, Astwood PM, Nixon BT, Ausubel FM
Nucleic Acids Res. 1987;15(19):7921-34 - PMID: 3671068 - PMCID: PMC306317

Rhizobium meliloti has three functional copies of the nodD symbiotic regulatory gene.

Honma MA, Ausubel FM
Proc Natl Acad Sci U S A. 1987;84(23):8558-62 - PMID: 3479806 - PMCID: PMC299584

Conserved domains in bacterial regulatory proteins that respond to environmental stimuli.

Ronson CW, Nixon BT, Ausubel FM
Cell. 1987;49(5):579-81 - PMID: 3555840

The yeast ARD1 gene product is required for repression of cryptic mating-type information at the HML locus.

Whiteway M, Freedman R, Van Arsdell S, Szostak JW, Thorner J
Mol Cell Biol. 1987;7(10):3713-22 - PMID: 3316986 - PMCID: PMC368027

Identification of healed terminal DNA fragments in linear minichromosomes of Schizosaccharomyces pombe.

Matsumoto T, Fukui K, Niwa O, Sugawara N, Szostak JW, Yanagida M
Mol Cell Biol. 1987;7(12):4424-30 - PMID: 2830493 - PMCID: PMC368126

Structural conventions for group I introns.

Burke JM, Belfort M, Cech TR, Davies RW, Schweyen RJ, Shub DA, Szostak JW, Tabak HF
Nucleic Acids Res. 1987;15(18):7217-21 - PMID: 3658691 - PMCID: PMC306243

Roles of the 2 microns gene products in stable maintenance of the 2 microns plasmid of Saccharomyces cerevisiae.

Reynolds AE, Murray AW, Szostak JW
Mol Cell Biol. 1987;7(10):3566-73 - PMID: 3316982 - PMCID: PMC368010

Artificial chromosomes.

Murray AW, Szostak JW
Sci Am. 1987;257(5):62-8 - PMID: 3317814

Chromosome segregation in mitosis and meiosis.

Murray AW, Szostak JW
Annu Rev Cell Biol. 1987;1:289-315 - PMID: 3916318

Monoclonal antibody and ligand binding sites of the T cell erythrocyte receptor (CD2).

Peterson A, Seed B
Nature. 1987;329(6142):842-6 - PMID: 2444890

Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system.

Aruffo A, Seed B
Proc Natl Acad Sci U S A. 1987;84(23):8573-7 - PMID: 2825196 - PMCID: PMC299587

An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2.

Seed B
Nature. 1987;329(6142):840-2 - PMID: 3313052

Expression and function of CD4 in a murine T-cell hybridoma.

Sleckman BP, Peterson A, Jones WK, Foran JA, Greenstein JL, Seed B, Burakoff SJ
Nature. 1987;328(6128):351-3 - PMID: 3037388

Syrinx 2A: an improved lambda phage vector designed for screening DNA libraries by recombination in vivo.

Lutz CT, Hollifield WC, Seed B, Davie JM, Huang HV
Proc Natl Acad Sci U S A. 1987;84(13):4379-83 - PMID: 2955406 - PMCID: PMC305092

Molecular cloning of two CD7 (T-cell leukemia antigen) cDNAs by a COS cell expression system.

Aruffo A, Seed B
EMBO J. 1987;6(11):3313-6 - PMID: 3501369 - PMCID: PMC553785

Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.

Seed B, Aruffo A
Proc Natl Acad Sci U S A. 1987;84(10):3365-9 - PMID: 2437578 - PMCID: PMC304871

Preproparathyroid hormone: Use of mutants to study secretion. In: Cohn DV, Martin TJ, Meunier PJ, eds.

Kronenberg HM, Wiren KM, Freeman MW, JT Potts Jr
Calcium Regulation and Bone Metabolism: Basic and Clinical Aspects, Vol. 9. Amsterdam: Excerpta Medica. 1987;9:773-777

Preproparathyroid hormone: a model for analyzing the secretory pathway.

Wiren KM, Freeman MW, Potts JT Jr, HM Kronenberg
Ann NY Acad Sci. 1987;493:43-49

Chemistry, molecular biology, and mode of action of parathyroid hormone.

Potts, JT Jr, Nussbaum S, Wiren K, Freeman M, Igarashi T, Okazaki T, Zajac J, Abou-Samra AB, Bringhurst FR, Segre G, HM Kronenberg
Proceedings of the First International Conference on New Actions of Parathyroid Hormone. Kobe, Japan. 1987;:ePub

Preproparathyroid hormone. A model for analyzing the secretory pathway.

Wiren KM, Freeman MW, Potts JT, Kronenberg HM
Ann N Y Acad Sci. 1987;493:43-9 - PMID: 3473968

Consequences of amino-terminal deletions of preproparathyroid hormone signal sequence.

Freeman MW, Wiren KM, Rapoport A, Lazar M, Potts JT, Kronenberg HM
Mol Endocrinol. 1987;1(9):628-38 - PMID: 3153480

A human and a plant intron-containing tRNATyr gene are both transcribed in a HeLa cell extract but spliced along different pathways.

van Tol H, Stange N, Gross HJ, Beier H
EMBO J. 1987;6(1):35-41 - PMID: 3502708 - PMCID: PMC553353

A nuclear Nicotiana DNA sequence homologous to the 5' half of tRNATyr may have derived from reverse transcription of a pre-tRNA splicing intermediate.

Stange N, Gross HJ, Beier H
Nucleic Acids Res. 1987;15(13):5477 - PMID: 3648681 - PMCID: PMC305973

A cell-free plant extract for accurate pre-tRNA processing, splicing and modification.

Stange N, Beier H
EMBO J. 1987;6(9):2811-8 - PMID: 3678205 - PMCID: PMC553707

Gibberellin-Induced Changes in the Populations of Translatable mRNAs and Accumulated Polypeptides in Dwarfs of Maize and Pea.

Chory J, Voytas DF, Olszewski NE, Ausubel FM
Plant Physiol. 1987;83(1):15-23 - PMID: 16665192 - PMCID: PMC1056291

Rhizobium symbiotic genes required for nodulation of legume and nonlegume hosts.

Marvel DJ, Torrey JG, Ausubel FM
Proc Natl Acad Sci U S A. 1987;84(5):1319-23 - PMID: 16593814 - PMCID: PMC304419

Burn therapy 1985: acute management.

Tompkins RG, Burke JF
Intensive Care Med. 1986;12(4):289-95 - PMID: 3531277

Prompt eschar excision: a treatment system contributing to reduced burn mortality. A statistical evaluation of burn care at the Massachusetts General Hospital (1974-1984).

Tompkins RG, Burke JF, Schoenfeld DA, Bondoc CC, Quinby WC, Behringer GC, Ackroyd FW
Ann Surg. 1986;204(3):272-81 - PMID: 3753058 - PMCID: PMC1251276

Biological nitrogen fixation: recent advances and future prospects.

Ausubel FM
Regul Toxicol Pharmacol. 1986;6(1):1-10 - PMID: 3704206

Symbiotic nitrogen fixation: developmental genetics of nodule formation.

Lang-Unnasch N, Dunn K, Ausubel FM
Cold Spring Harb Symp Quant Biol. 1986;50:555-63 - PMID: 3868494

Paraquat-mediated selection for mutations in the manganese-superoxide dismutase gene sodA.

Bloch CA, Ausubel FM
J Bacteriol. 1986;168(2):795-8 - PMID: 3023287 - PMCID: PMC213554

Construction and behavior of circularly permuted and telocentric chromosomes in Saccharomyces cerevisiae.

Murray AW, Szostak JW
Mol Cell Biol. 1986;6(9):3166-72 - PMID: 3537731 - PMCID: PMC367052

An alternative pathway for meiotic chromosome segregation in yeast.

Dawson DS, Murray AW, Szostak JW
Science. 1986;234(4777):713-7 - PMID: 3535068

Enzymatic activity of the conserved core of a group I self-splicing intron.

Szostak JW
Nature. 1986;322(6074):83-6 - PMID: 3014350

Chromosome length controls mitotic chromosome segregation in yeast.

Murray AW, Schultes NP, Szostak JW
Cell. 1986;45(4):529-36 - PMID: 3518944

Structure and expression of the human parathyroid hormone gene.

Kronenberg HM, Igarashi T, Freeman MW, Okazaki T, Brand SJ, Wiren KM, Potts JT
Recent Prog Horm Res. 1986;42:641-63 - PMID: 3526456

A gene for the major cytoplasmic tRNATyr from Nicotiana rustica contains a 13 nucleotides long intron.

Stange N, Beier H
Nucleic Acids Res. 1986;14(21):8691 - PMID: 3641192 - PMCID: PMC311891

Two-component regulatory systems responsive to environmental stimuli share strongly conserved domains with the nitrogen assimilation regulatory genes ntrB and ntrC.

Nixon BT, Ronson CW, Ausubel FM
Proc Natl Acad Sci U S A. 1986;83(20):7850-4 - PMID: 3020561 - PMCID: PMC386820

Expression of the ribulose-1,5-bisphosphate carboxylase large subunit gene and three small subunit genes in two cell types of maize leaves.

Sheen JY, Bogorad L
EMBO J. 1986;5(13):3417-22 - PMID: 16453739 - PMCID: PMC1167374

Improved management of the perineal wound after proctectomy.

Tompkins RG, Warshaw AL
Ann Surg. 1985;202(6):760-5 - PMID: 4073988 - PMCID: PMC1251011

Conservation of nodulation genes between Rhizobium meliloti and a slow-growing Rhizobium strain that nodulates a nonlegume host.

Marvel DJ, Kuldau G, Hirsch A, Richards E, Torrey JG, Ausubel FM
Proc Natl Acad Sci U S A. 1985;82(17):5841-5 - PMID: 16593600 - PMCID: PMC390649

Nitrogen fixation specific regulatory genes of Klebsiella pneumoniae and Rhizobium meliloti share homology with the general nitrogen regulatory gene ntrC of K. pneumoniae.

Buikema WJ, Szeto WW, Lemley PV, Orme-Johnson WH, Ausubel FM
Nucleic Acids Res. 1985;13(12):4539-55 - PMID: 2989799 - PMCID: PMC321805

Specific Saccharomyces cerevisiae genes are expressed in response to DNA-damaging agents.

Ruby SW, Szostak JW
Mol Cell Biol. 1985;5(1):75-84 - PMID: 3920512 - PMCID: PMC366680

The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways.

Whiteway M, Szostak JW
Cell. 1985;43(2 Pt 1):483-92 - PMID: 3907857

Fungal recombination.

Orr-Weaver TL, Szostak JW
Microbiol Rev. 1985;49(1):33-58 - PMID: 3884994 - PMCID: PMC373016

Minimal size plasmids containing an M13 origin for production of single-strand transducing particles.

Levinson A, Silver D, Seed B
J Mol Appl Genet. 1985;2(6):507-17 - PMID: 6099398

Differential expression of the ribulose bisphosphate carboxylase large subunit gene in bundle sheath and mesophyll cells of developing maize leaves is influenced by light.

Sheen JY, Bogorad L
Plant Physiol. 1985;79(4):1072-6 - PMID: 16664532 - PMCID: PMC1075029

Nodule-specific polypeptides from effective alfalfa root nodules and from ineffective nodules lacking nitrogenase.

Lang-Unnasch N, Ausubel FM
Plant Physiol. 1985;77(4):833-9 - PMID: 16664146 - PMCID: PMC1064615

Regulation of nitrogen fixation genes.

Ausubel FM
Cell. 1984;37(1):5-6 - PMID: 6373013

Physical and genetic characterization of Rhizobium meliloti symbiotic mutants.

Buikema WJ, Long SR, Brown SE, van den Bos RC, Earl C, Ausubel FM
J Mol Appl Genet. 1984;2(3):249-60 - PMID: 6363587

Rhizobium meliloti nodulation genes allow Agrobacterium tumefaciens and Escherichia coli to form pseudonodules on alfalfa.

Hirsch AM, Wilson KJ, Jones JD, Bang M, Walker VV, Ausubel FM
J Bacteriol. 1984;158(3):1133-43 - PMID: 6327629 - PMCID: PMC215561

Construction of a correlated physical and genetic map of the Klebsiella pneumoniae hisDGO region using transposon Tn5 mutagenesis.

de Bruijn FJ, Stroke IL, Marvel DJ, Ausubel FM
EMBO J. 1984;2(10):1831-8 - PMID: 6315405 - PMCID: PMC555367

Mutations affecting regulation of the Klebsiella pneumoniae nifH (nitrogenase reductase) promotor.

Brown SE, Ausubel FM
J Bacteriol. 1984;157(1):143-7 - PMID: 6360993 - PMCID: PMC215143

DNA sequences of telomeres maintained in yeast.

Shampay J, Szostak JW, Blackburn EH
Nature. 1984;310(5973):154-7 - PMID: 6330571

Transfer of yeast telomeres to linear plasmids by recombination.

Dunn B, Szauter P, Pardue ML, Szostak JW
Cell. 1984;39(1):191-201 - PMID: 6091911

Potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in 9L rat brain tumor cells by methylglyoxal-bis(guanylhydrazone), an inhibitor of S-adenosyl-L-methionine decarboxylase.

Hung DT, Oredsson SM, Pegg AE, Deen DF, Marton LJ
Eur J Cancer Clin Oncol. 1984;20(3):417-20 - PMID: 6538500

Decreased cell kill of vincristine and methotrexate against 9L rat brain tumor cells in vitro caused by alpha-difluoromethylornithine-induced polyamine depletion.

Alhonen-Hongisto L, Hung DT, Deen DF, Marton LJ
Cancer Res. 1984;44(10):4440-2 - PMID: 6432313

A comparison of postmigration and migration-coupled mismatch correction mechanisms for branch migration-mediated gene conversion.

Seed B
Genetics. 1984;106(3):549-67 - PMID: 6706113 - PMCID: PMC1224256

A Rhizobium meliloti symbiotic regulatory gene.

Szeto WW, Zimmerman JL, Sundaresan V, Ausubel FM
Cell. 1984;36(4):1035-43 - PMID: 6423287

Conditionally replicating plasmid vectors that can integrate into the Klebsiella pneumoniae chromosome via bacteriophage P4 site-specific recombination.

Ow DW, Ausubel FM
J Bacteriol. 1983;155(2):704-13 - PMID: 6307977 - PMCID: PMC217740

Ultrastructural analysis of ineffective alfalfa nodules formed by nif::Tn5 mutants of Rhizobium meliloti.

Hirsch AM, Bang M, Ausubel FM
J Bacteriol. 1983;155(1):367-80 - PMID: 6575011 - PMCID: PMC217689

Molecular characterization of Tn5-induced symbiotic (Fix-) mutants of Rhizobium meliloti.

Zimmerman JL, Szeto WW, Ausubel FM
J Bacteriol. 1983;156(3):1025-34 - PMID: 6196347 - PMCID: PMC217946

Nitrogen fixation by Klebsiella pneumoniae is inhibited by certain multicopy hybrid nif plasmids.

Riedel GE, Brown SE, Ausubel FM
J Bacteriol. 1983;153(1):45-56 - PMID: 6336738 - PMCID: PMC217340

The genetic engineering of nitrogen fixation.

Earl CD, Ausubel FM
Nutr Rev. 1983;41(1):1-6 - PMID: 6302610

Is there left-handed DNA at the ends of yeast chromosomes?

Walmsley RM, Szostak JW, Petes TD
Nature. 1983;302(5903):84-6 - PMID: 6338397

Multiple, tandem plasmid integration in Saccharomyces cerevisiae.

Orr-Weaver TL, Szostak JW
Mol Cell Biol. 1983;3(4):747-9 - PMID: 6343844 - PMCID: PMC368590

Recombination between sequences in nonhomologous positions.

Sugawara N, Szostak JW
Proc Natl Acad Sci U S A. 1983;80(18):5675-9 - PMID: 6351064 - PMCID: PMC384321

A rapid procedure for the construction of linear yeast plasmids.

Szostak JW
Methods Enzymol. 1983;101:245-52 - PMID: 6310327

Replication and resolution of telomeres in yeast.

Szostak JW
Cold Spring Harb Symp Quant Biol. 1983;47 Pt 2:1187-94 - PMID: 6305577

Genetic applications of yeast transformation with linear and gapped plasmids.

Orr-Weaver TL, Szostak JW, Rothstein RJ
Methods Enzymol. 1983;101:228-45 - PMID: 6310326

The double-strand-break repair model for recombination.

Szostak JW, Orr-Weaver TL, Rothstein RJ, Stahl FW
Cell. 1983;33(1):25-35 - PMID: 6380756

Cloning regulated yeast genes from a pool of lacZ fusions.

Ruby SW, Szostak JW, Murray AW
Methods Enzymol. 1983;101:253-69 - PMID: 6310328

Pedigree analysis of plasmid segregation in yeast.

Murray AW, Szostak JW
Cell. 1983;34(3):961-70 - PMID: 6354471

Yeast vectors with negative selection.

Brown PA, Szostak JW
Methods Enzymol. 1983;101:278-90 - PMID: 6310330

Yeast recombination: the association between double-strand gap repair and crossing-over.

Orr-Weaver TL, Szostak JW
Proc Natl Acad Sci U S A. 1983;80(14):4417-21 - PMID: 6308623 - PMCID: PMC384049

Construction of artificial chromosomes in yeast.

Murray AW, Szostak JW
Nature. 1983;305(5931):189-93 - PMID: 6350893

Construction of specific chromosomal rearrangements in yeast.

Sugawara N, Szostak JW
Methods Enzymol. 1983;101:269-78 - PMID: 6310329

A critique of materials submitted by dentists to dental laboratories for the fabrication of removable partial dentures.

Hardy F, Stuart LM
Quintessence Dent Technol. 1983;7(2):93-5 - PMID: 6344150

Depletion of intracellular polyamines may alter DNA conformation in 9L rat brain tumor cells.

Hung DT, Marton LJ, Deen DF, Shafer RH
Science. 1983;221(4608):368-70 - PMID: 6408733

Plasmid vectors for the rapid isolation and transcriptional analysis of human beta-globin gene alleles.

Little PF, Treisman R, Bierut L, Seed B, Maniatis T
Mol Biol Med. 1983;1(5):473-88 - PMID: 6094959

Purification of genomic sequences from bacteriophage libraries by recombination and selection in vivo.

Seed B
Nucleic Acids Res. 1983;11(8):2427-45 - PMID: 6856467 - PMCID: PMC325894

Nucleotide sequence of the human parathyroid hormone gene.

Vasicek TJ, McDevitt BE, Freeman MW, Fennick BJ, Hendy GN, Potts JT, Rich A, Kronenberg HM
Proc Natl Acad Sci U S A. 1983;80(8):2127-31 - PMID: 6220408 - PMCID: PMC393770

ISRm1: A Rhizobium meliloti insertion sequence that transposes preferentially into nitrogen fixation genes.

Ruvkun GB, Long SR, Meade HM, van den Bos RC, Ausubel FM
J Mol Appl Genet. 1983;1(5):405-18 - PMID: 6296251

Regulation of nitrogen metabolism genes by nifA gene product in Klebsiella pneumoniae.

Ow DW, Ausubel FM
Nature. 1983;301(5898):307-13 - PMID: 6337346

Klebsiella pneumoniae nifA product activates the Rhizobium meliloti nitrogenase promoter.

Sundaresan V, Jones JD, Ow DW, Ausubel FM
Nature. 1983;301(5902):728-32 - PMID: 6338395

Promoters regulated by the glnG (ntrC) and nifA gene products share a heptameric consensus sequence in the -15 region.

Ow DW, Sundaresan V, Rothstein DM, Brown SE, Ausubel FM
Proc Natl Acad Sci U S A. 1983;80(9):2524-8 - PMID: 6133280 - PMCID: PMC393858

Activation of Klebsiella pneumoniae and Rhizobium meliloti nitrogenase promoters by gln (ntr) regulatory proteins.

Sundaresan V, Ow DW, Ausubel FM
Proc Natl Acad Sci U S A. 1983;80(13):4030-4 - PMID: 6306658 - PMCID: PMC394194

Unequal crossing-over associated with asymmetrical synapsis between nomadic elements in the Drosophila melanogaster genome.

Goldberg ML, Sheen JY, Gehring WJ, Green MM
Proc Natl Acad Sci U S A. 1983;80(16):5017-21 - PMID: 16593354 - PMCID: PMC384179

Molecular genetics of symbiotic nitrogen fixation.

Ausubel FM
Cell. 1982;29(1):1-2 - PMID: 6286135

The cloning and transposon Tn5 mutagenesis of the glnA region of Klebsiella pneumoniae: identification of glnR, a gene involved in the regulation of the nif and hut operons.

de Bruijn FJ, Ausubel FM
Mol Gen Genet. 1982;183(2):289-97 - PMID: 6120440

Construction of a broad host range cosmid cloning vector and its use in the genetic analysis of Rhizobium mutants.

Friedman AM, Long SR, Brown SE, Buikema WJ, Ausubel FM
Gene. 1982;18(3):289-96 - PMID: 6290332

Structural studies of alfalfa roots infected with nodulation mutants of Rhizobium meliloti.

Hirsch AM, Long SR, Bang M, Haskins N, Ausubel FM
J Bacteriol. 1982;151(1):411-9 - PMID: 7085566 - PMCID: PMC220253

Cloning yeast telomeres on linear plasmid vectors.

Szostak JW, Blackburn EH
Cell. 1982;29(1):245-55 - PMID: 6286143

Are you expecting a miracle?

Hardy F, Stuart LM, Ross LA
J Md State Dent Assoc. 1982;25(1):19-20 - PMID: 7042882

Laboratory prescriptions for removable partial dentures.

Hardy F, Stuart LM, Travaglini EA
J Md State Dent Assoc. 1982;25(3):108-9 - PMID: 6757356

Diazotizable arylamine cellulose papers for the coupling and hybridization of nucleic acids.

Seed B
Nucleic Acids Res. 1982;10(5):1799-810 - PMID: 7071022 - PMCID: PMC320567

Representation of DNA sequences in recombinant DNA libraries prepared by restriction enzyme partial digestion.

Seed B, Parker RC, Davidson N
Gene. 1982;19(2):201-9 - PMID: 6293929

Theoretical study of the fraction of a long-chain DNA that can be incorporated in a recombinant DNA partial-digest library.

Seed B
Biopolymers. 1982;21(9):1793-810 - PMID: 7126756

Physical and genetic characterization of symbiotic and auxotrophic mutants of Rhizobium meliloti induced by transposon Tn5 mutagenesis.

Meade HM, Long SR, Ruvkun GB, Brown SE, Ausubel FM
J Bacteriol. 1982;149(1):114-22 - PMID: 6274841 - PMCID: PMC216598

Directed transposon Tn5 mutagenesis and complementation analysis of Rhizobium meliloti symbiotic nitrogen fixation genes.

Ruvkun GB, Sundaresan V, Ausubel FM
Cell. 1982;29(2):551-9 - PMID: 6288262

Specific protection of nucleotides in the lac operator from DMS methylation and DNase I nicking by crude bacterial cell extracts.

Ruvkun GB, Sundaresan V, Ausubel FM
Gene. 1982;18(3):247-55 - PMID: 6290328

Directed transposon Tn5 mutagenesis and complementation analysis of Rhizobium meliloti symbiotic nitrogen fixation genes.

Ruvkun GB, Sundaresan V, Ausubel FM
Cell. 1982;29(2):551-9 - PMID: 6288262

Molecular genetic analysis of Klebsiella pneumoniae nitrogen-fixation (nif) genes.

Ausubel FM, Cannon FC
Cold Spring Harb Symp Quant Biol. 1981;45 Pt 2:487-99 - PMID: 6266743

Recombinant P4 bacteriophages propagate as viable lytic phages or as autonomous plasmids in Klebsiella pneumoniae.

Ow DW, Ausubel FM
Mol Gen Genet. 1981;180(1):165-75 - PMID: 6255293

Nucleotide sequence of the gene coding for the nitrogenase iron protein from Klebsiella pneumoniae.

Sundaresan V, Ausubel FM
J Biol Chem. 1981;256(6):2808-12 - PMID: 6259144

DNA sequence of a mutation in the leader region of the yeast iso-1-cytochrome c mRNA.

Stiles JI, Szostak JW, Young AT, Wu R, Consaul S, Sherman F
Cell. 1981;25(1):277-84 - PMID: 6268305

Yeast transformation: a model system for the study of recombination.

Orr-Weaver TL, Szostak JW, Rothstein RJ
Proc Natl Acad Sci U S A. 1981;78(10):6354-8 - PMID: 6273866 - PMCID: PMC349037

Sensitization of 9L rat brain gliosarcoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.

Hung DT, Deen DF, Seidenfeld J, Marton LJ
Cancer Res. 1981;41(7):2783-5 - PMID: 6788362

A general method for site-directed mutagenesis in prokaryotes.

Ruvkun GB, Ausubel FM
Nature. 1981;289(5793):85-8 - PMID: 6256652

A general method for site-directed mutagenesis in prokaryotes.

Ruvkun GB, Ausubel FM
Nature. 1981;289(5793):85-8 - PMID: 6256652

Unequal crossing over in the ribosomal DNA of Saccharomyces cerevisiae.

Szostak JW, Wu R
Nature. 1980;284(5755):426-30 - PMID: 6987539

Hybridization with synthetic oligonucleotides.

Szostak JW, Stiles JI, Tye BK, Chiu P, Sherman F, Wu R
Methods Enzymol. 1980;68:419-28 - PMID: 161605

Preparation of an ecdysone immunogen for radioimmunoassay work.

Hung DT, Benner SA, Williams CM
J Biol Chem. 1980;255(13):6047-8 - PMID: 7190146

Two-dimensional agarose gel electrophoresis "SeaPlaque" agarose dimension.

Parker RC, Seed B
Methods Enzymol. 1980;65(1):358-63 - PMID: 6246359

The effect of oxandrolone on low and high density lipoprotein profiles in retired breeder rats.

Freeman MW, Spring-Mills E, Jones AL
J Gerontol. 1980;35(1):31-8 - PMID: 7350219

Interspecies homology of nitrogenase genes.

Ruvkun GB, Ausubel FM
Proc Natl Acad Sci U S A. 1980;77(1):191-5 - PMID: 6987649 - PMCID: PMC348234

Interspecies homology of nitrogenase genes.

Ruvkun GB, Ausubel FM
Proc Natl Acad Sci U S A. 1980;77(1):191-5 - PMID: 6987649 - PMCID: PMC348234

Radiochemical identification of the kil gene product of bacteriophage lambda.

Greer H, Ausubel FM
Virology. 1979;95(2):577-80 - PMID: 462802

Cyanobacterial ribonucleic acid polymerases recognize lambda promoters.

Miller SS, Ausubel FM, Bogorad L
J Bacteriol. 1979;140(1):246-50 - PMID: 159286 - PMCID: PMC216802

Directive segregation in the basis of colE1 plasmid incompatibility.

Bedbrook JR, Lehrach H, Ausubel FM
Nature. 1979;281(5731):447-52 - PMID: 386132

Glutamine synthetase mutations which affect expression of nitrogen fixation genes in Klebsiella pneumoniae.

Ausubel FM, Bird SC, Durbin KJ, Janssen KA, Margolskee RF, Peskin AP
J Bacteriol. 1979;140(2):597-606 - PMID: 40960 - PMCID: PMC216687

Overlapping sequences of Klebsiella pneumoniae nifDNA cloned and characterized.

Cannon FC, Riedel GE, Ausubel FM
Mol Gen Genet. 1979;174(1):59-66 - PMID: 384162

Insertion of a genetic marker into the ribosomal DNA of yeast.

Szostak JW, Wu R
Plasmid. 1979;2(4):536-54 - PMID: 394173

Physical map of chromosomal nitrogen fixation (nif) genes of Klebsiella pneumoniae.

Riedel GE, Ausubel FM, Cannon FC
Proc Natl Acad Sci U S A. 1979;76(6):2866-70 - PMID: 379866 - PMCID: PMC383710

Regional in vitro uptake of a synthetic 3H-labeled-melanin into rat brain.

Porter JR, Kastin AJ, Pelle-Day G, Tompkins RG
Brain Res Bull. 1978;2(6):401-4 - PMID: 606338

Melanin in the rat brain.

Kastin AJ, Kuzemchak B, Tompkins RG, Schally AV, Miller MC
Brain Res Bull. 1977;1(6):567-72 - PMID: 1021212

Specific binding of a synthetic oligodeoxyribonucleotide to yeast cytochrome c mRNA.

Szostak JW, Stiles JI, Bahl CP, Wu R
Nature. 1977;265(5589):61-3 - PMID: 189200

Recombinant plasmid that carries part of the nitrogen fixation (nif) gene cluster of Klebsiella pneumoniae.

Cannon FC, Riedel GE, Ausubel FM
Proc Natl Acad Sci U S A. 1977;74(7):2963-7 - PMID: 331321 - PMCID: PMC431364

Recombination between bacterial plasmids leading to the formation of plasmid multimers.

Bedbrook JR, Ausubel FM
Cell. 1976;9(4 PT 2):707-16 - PMID: 797459

Radiochemical purification of bacteriophage lambda integrase.

Ausubel FM
Nature. 1974;247(437):152-4 - PMID: 4589454

Early and late hemodynamic effects of mitral commissurotomy.

LYONS WS, TOMPKINS RG, KIRKLIN JW, WOOD EH
J Lab Clin Med. 1959;53(4):499-516 - PMID: 13654887

Pulmonary artery wedge pressures in mitral valve disease; relationship to left atrial pressures.

CONNOLLY DC, TOMPKINS RG, LEV R, KIRKLIN JW, WOOD EH
Proc Staff Meet Mayo Clin. 1953;28(3):72-8 - PMID: 13014128

Quantitation of beat-to-beat changes in stroke volume from the aortic pulse contour in man.

WARNER HR, SWAN HJ, CONNOLLY DC, TOMPKINS RG, WOOD EH
J Appl Physiol. 1953;5(9):495-507 - PMID: 13034677

Surgical treatment of infundibular stenosis with intact ventricular septum.

KIRKLIN JW, OPENSHAW CR, TOMPKINS RG
Ann Surg. 1953;137(2):228-31 - PMID: 13017523 - PMCID: PMC1802459