Seed
Lab People
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Linda
Chun Assistant in Molecular
Biology
Education BS
in Chemistry, Illinois Institute of Technology; PhD in Neurobiology,
Harvard University
My research focus is to understand the molecular mechanisms
that underlie immune evasion by tumor cells. Gene arrays and high-throughput
genetic screening by expression cloning and RNAi are being used to
identify signalling pathways that mediate escape in an ocular tumor
model system. |
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Isin Dalkilic-Liddle Research Fellow
Education BS in Biology and Chemistry, MIT; PhD in Genetics, Harvard University
My current research focuses on mechanisms of nuclear receptor activation. More specifically, I am working on identifying pathways that activate and/or repress orphan nuclear receptor ERR1 and its coactivator PGC1 mediated transcription through utilizing whole genome-wide expression cloning. |
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Sandip Datta Research Fellow
Education PhD, Jawaharlal Nehru University, New Delhi
Interests Systems Biology and Bioinformatics
I am interested in applying the methods of complex systems analysis to the study of biological systems. My current project is to examine the implications of chaos in biological feedback and control circuits. |
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Yao-Ting Huang Research Fellow
Education PhD, National Taiwan University
Interests Pharmacodynamics and drug discovery
I am a pharmacist and pharmacologist by training. I'm primarily interested in investigating drug mechanisms using multidisciplinary knowledge and exploring information obtained from clinical trials to increase our understanding of how drugs work. My current focus is on evaluating the therapeutic efficacy of immunotoxins. |
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Robin
Ketteler Research Fellow
Education PhD Albert Ludwigs
University, Freiburg and Max Planck Institute for Immunobiology, Freiburg
Interests Signal Transduction,
Virology, Gene Therapy
My current research focuses on mechanisms of cancer-related signaling
pathways. Specifically, I am investigating the role of sub-cellular
compartmentalization in signal transduction cascades by genome-wide
expression cloning. Additionally, I am interested in developing novel
tools to study sub-cellular processes by modifications in reporter
genes such as GFP or luciferase and improved vector design. |
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Hwijin Kim Research Fellow
Education PhD, U. of Wisconsin-Madison
Interests
My research has focused on the application of mathematics, statistics and computer simulation as tools to facilitate an integrated understanding of virus-host interactions and their therapeutic implications. I have worked on the intracellular and population-level dynamics of various viruses including HIV-1, HBV, HCV, and bacteriophage Qb, and have suggested novel and robust antiviral strategies based on their dynamic characteristics. I am currently working on cDNA library screening, both experimental and computational. |
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Young
Bae Kim Research Fellow
Education BS Seoul National University;
MS, Seoul National University; PhD, University of Tokyo
Interests
Functional genomics and new technology development
My main research projects aims to reveal modulators of cellular signal
transduction pathways and develop new technologies to study them.
Specifically, I am working on TGF-beta/Smad pathway utilizing high-throughput
screens and mouse genetic approaches. The other project involves bacterial
genetic approaches to develop new technologies, which would allow
us to handle the mouse genome more efficiently. |
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Aimee
Landry Research Technologist
Education BSc, St. Lawrence University
Interests
I’m currently working on several projects; the first utilizes
high-throughput automation technology in order to screen cDNA libraries
for novel proteins which interact with the serum response element
(SRE). Other projects involve several PDZ-domain containing proteins,
specifically their biochemical and physiological roles in various
signaling pathways that lead up to an immune response. |
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Chen Liu Bioinformatics
Specialist
Education
BM, Sun Yat-Sen University of Medical Sciences; MSc, Northeastern
University
Interests Development
of scientific tools for biologists and clinicians
I enjoy the development of new scientific tools for biological discovery
and also working on the development of a high-throughput data analysis
pipeline.
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Naifang
Lu Research Lab Manager
Education BM Second Medical College
of Beijing
Interests Develop
new technology and animal models
I have been working with gene targeting projects and generating transgenic
mice and knockout/knockin mice by pronuclear and blastocyst microinjection
since 1991. Before joining Dr. Seed's lab in 1995, I worked for Dr.
Richard Behringer at the M.D. Anderson Cancer Center and for Dr. Martin M.
Matzuk at Baylor College of Medicine. I am currently engaged in projects
to develop new technology and generate new mouse models. |
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Soon-Young
Na Research Fellow
Education BS/MS/PhD Chonnam National
University, Korea
Interests
Cell signal transduction, development of new model system
My primary project is to investigate new molecules which are coming from human
cDNA library screens with NF-kB. Another project is to develop the model system
for mammalian transcription and translation research. |
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Rasma
Niedra Research Lab Technologist
Education BS, Geneva College
Interests
Tissue culture
I culture cell lines for the Center for Computational and Integrative Biology, and prepare media and reagents. I've been working for Brian Seed for a number of years. The new environment in the Simches Research building is a pleasure to work in. |
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Changhong
Pang Research Team Leader
I
Education BS, Shenyang
Pharmaceutical University, China; MS, PhD, Kitasato University,
Japan
Interests Genetic technology,
molecular biology and drug discovery
I obtained my Ph.D. at Professor Omura's lab at Kitasato University
in Tokyo. My Ph.D. thesis was "The Molecular Genetics of Avermectin
Biosynthesis and its Application". I have done one year of postdoctoral
research in genetic technologies, which I worked on at Kitasato institute.
I also worked at a molecular biology group, R&D Pfizer, in Japan
before I joined the Seed lab. I am very interested in developing new
genetic technologies and new drug discovery research. I spend leisure
time traveling with my family and in sports. |
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Harald
Prosper Senior Animal Technologist
Education Lab Animal Technologist certification
Interests Taking care of the lab animals and watching soccer
I maintain the stock of mice for the Seed Lab, Freeman Lab and Oettinger Lab. I have worked for the Massachusetts General Hospital for 11 years, in the animal facilities for the entire period. My plan is to take the Lab Animal Technologist Generalist certification next. I like playing and watching soccer, and I especially enjoy spending time with my three children. |
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Slim Sassi Research Fellow
Education PhD, Biomedical Sciences, College of Medicine, U. of Florida
Interests Molecular evolution, molecular biology, evolution of complex systems and cool new technologies
I am currently working on a project to decipher complex biological systems. I will attempt to develop an approach to synergize molecular evolution and molecular biology to understand these systems. This approach will involve computational molecular evolutionary methods, high-throughput genetic screening and other classical molecular biology methods. More details soon… |
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Prabhat Kumar Singhal Research Fellow
Education PhD, Centre for DNA Fingerprinting and Diagnostics (CDFD)
Interests Signal transduction, stem cells and small RNA molecular biology
My primary research project will be on the dedifferentiation of cell types into stem cells. Visit again soon for more details.
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Athanasia
(Nancy) Spandidos Research
Fellow
Education B
Sc, University of Glasgow; PhD, University of Cambridge
Interests Novel technologies
I obtained my B.Sc. from the University
of Glasgow, Scotland and my Ph.D. from the University of Cambridge,
England, working at the MRC Laboratory of Molecular Biology. I worked
then on developing new methods for proteomics based on 2-D electrophoresis
and mass spectrometry. I continued working at the MRC Laboratory of
Molecular Biology as a post-doctoral fellow before joining the Seed
lab in January 2004. I joined the Seed lab because I am interested
in developing new technologies for molecular biology studies. |
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Ming-Hsiang (Vicky) Sung Research Fellow
Education PhD in Molecular Microbiology and Immunology, U. of Southern California
Interests I want to understand the mechanisms of disease development and find better cures for them
I was trained in the field of molecular microbiology and immunology, specifically with HBV, HCV, HDV, HIV, Mycoplasma, Neisseria, Trypanosoma and a little gene therapy in human ES cells. My current project is to develop a novel strategy for studying signal transduction and therapy for diseases.
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Huajun Wang Bioinformatics Specialist
Education PhD in Neurobiology, Columbia University
Interests Bioinformatics software development
My main interest is biological and chemical data management, analysis, and integration. After a bioinformatics postdoc training at Jackson Laboratory, I have mostly worked on bioinformatics software supporting the human genome project, SNP discovery and large-scale protein-protein interaction study. |
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Qiang
Xie Research Fellow
Education MD, Sun Yat-sen
University of Medical Sciences, China; PhD, Indiana University
Interests Genetic engineering,
immunology, cell biology
I studied medicine at the Sun Yat-Sen University of Medical Sciences
from 1991 to 1996 and obtained a Ph.D. from Indiana University in 2004.
My main interests are in developing novel mouse models for immune diseases
and in inventing novel technologies for genetic engineering. |
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Arum (Amy) Yu Research Fellow
Education PhD, MIT
Interests Cooking, especially desserts
My primary research interest is in printing DNA features. My goal in Dr. Seed's lab is to develop an efficient method to print biomolecule-based devices in a facile way. |
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Guo Ling
Zhou Research Fellow
Education BSc and MS,
Huazhong Agricultural University, China; Ph D, Chinese Academy of
Medical Science and Peking Union Medical College, China.
Interests
Regulation network of eukaryotic gene expression, immunology, mouse
model for diseases
I obtained my Ph.D. studying the regulation of globin gene clusters
and the memory mechanism of epigenetic information during cell division,
after I completed my B.Sc. and M.S. majoring in crop genetics and breeding.
I joined the Seed lab in October 2005 because I am interested in chromosomal
engineering and developing new approaches for creating mouse models
used in the study of immunology.
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