Seed
Lab People
 |
|
Santosh Bhaskarabhatla Undergraduate Student
Education AB in Biological Sciences, Harvard [expected 2010]
Interests Neurobiology, computational biology, immunology, abiogenesis, information theory, astrophysics
What is life? It is the most important question, and life scientists tackle it every day. Working with Brian Seed in the CCIB gives me many opportunities to explore various fields within the life sciences, and to develop many skills in the laboratory. Currently, I am working on humanizing mice to create mouse models of certain human immunological conditions. I have also been working on a project related to ubiquitin ligases with Nancy Spandidos. After college, I will apply to either medical school or graduate school, but regardless, I wish to do scientific research professionally, thanks to my experiences in the Seed lab. |
| |
 |
|
Linda
Chun Assistant in Molecular
Biology
Education BS
in Chemistry, Illinois Institute of Technology; PhD in Neurobiology,
Harvard University
My research focus is to understand the molecular mechanisms
that underlie immune evasion by tumor cells. Gene arrays and high-throughput
genetic screening by expression cloning and RNAi are being used to
identify signalling pathways that mediate escape in an ocular tumor
model system. |
| |
 |
|
Isin Dalkilic-Liddle Research Fellow
Education BS in Biology and Chemistry, MIT; PhD in Genetics, Harvard University
My current research focuses on mechanisms of nuclear receptor activation. More specifically, I am working on identifying pathways that activate and/or repress orphan nuclear receptor ERR1 and its coactivator PGC1 mediated transcription through utilizing whole genome-wide expression cloning. |
| |
 |
|
Sandip Datta Research Fellow
Education PhD, Jawaharlal Nehru University, New Delhi
Interests Systems Biology and Bioinformatics
I am interested in applying the methods of complex systems analysis to the study of biological systems. My current project is to examine the implications of chaos in biological feedback and control circuits. |
 |
 |
|
Hwijin Kim Research Fellow
Education PhD, U. of Wisconsin-Madison
Interests
My research has focused on the application of mathematics, statistics and computer simulation as tools to facilitate an integrated understanding of virus-host interactions and their therapeutic implications. I have worked on the intracellular and population-level dynamics of various viruses including HIV-1, HBV, HCV, and bacteriophage Qb, and have suggested novel and robust antiviral strategies based on their dynamic characteristics. I am currently working on cDNA library screening, both experimental and computational. |
| |
 |
|
Young
Bae Kim Research Fellow
Education BS Seoul National University;
MS, Seoul National University; PhD, University of Tokyo
Interests
Functional genomics and new technology development
My main research projects aims to reveal modulators of cellular signal
transduction pathways and develop new technologies to study them.
Specifically, I am working on TGF-beta/Smad pathway utilizing high-throughput
screens and mouse genetic approaches. The other project involves bacterial
genetic approaches to develop new technologies, which would allow
us to handle the mouse genome more efficiently. |
| |
 |
|
Naifang
Lu Research Lab Manager
Education BM Second Medical College
of Beijing
Interests Develop
new technology and animal models
I have been working with gene targeting projects and generating transgenic
mice and knockout/knockin mice by pronuclear and blastocyst microinjection
since 1991. Before joining Dr. Seed's lab in 1995, I worked for Dr.
Richard Behringer at the M.D. Anderson Cancer Center and for Dr. Martin M.
Matzuk at Baylor College of Medicine. I am currently engaged in projects
to develop new technology and generate new mouse models. |
| |
 |
|
Soon-Young
Na Research Fellow
Education BS/MS/PhD Chonnam National
University, Korea
Interests
Cell signal transduction, development of new model system
My primary project is to investigate new molecules which are coming from human
cDNA library screens with NF-kB. Another project is to develop the model system
for mammalian transcription and translation research. |
| |
 |
|
Rasma
Niedra Research Lab Technologist
Education BS, Geneva College
Interests
Tissue culture
I culture cell lines for the Center for Computational and Integrative Biology, and prepare media and reagents. I've been working for Brian Seed for a number of years. The new environment in the Simches Research building is a pleasure to work in. |
| |
 |
|
Changhong
Pang Research Team Leader
I
Education BS, Shenyang
Pharmaceutical University, China; MS, PhD, Kitasato University,
Japan
Interests Genetic technology,
molecular biology and drug discovery
I obtained my Ph.D. at Professor Omura's lab at Kitasato University
in Tokyo. My Ph.D. thesis was "The Molecular Genetics of Avermectin
Biosynthesis and its Application". I have done one year of postdoctoral
research in genetic technologies, which I worked on at Kitasato institute.
I also worked at a molecular biology group, R&D Pfizer, in Japan
before I joined the Seed lab. I am very interested in developing new
genetic technologies and new drug discovery research. I spend leisure
time traveling with my family and in sports. |
| |
 |
|
Harald
Prosper Senior Animal Technologist
Education Lab Animal Technologist certification
Interests Taking care of the lab animals and watching soccer
I maintain the stock of mice for the Seed Lab, Freeman Lab and Oettinger Lab. I have worked for the Massachusetts General Hospital for 11 years, in the animal facilities for the entire period. My plan is to take the Lab Animal Technologist Generalist certification next. I like playing and watching soccer, and I especially enjoy spending time with my three children. |
| |
 |
|
Slim Sassi Research Fellow
Education PhD, Biomedical Sciences, College of Medicine, U. of Florida
Interests Molecular evolution, molecular biology, evolution of complex systems and cool new technologies
I am currently working on a project to decipher complex biological systems. I will attempt to develop an approach to synergize molecular evolution and molecular biology to understand these systems. This approach will involve computational molecular evolutionary methods, high-throughput genetic screening and other classical molecular biology methods. More details soon… |
| |
 |
|
Prabhat Kumar Singhal Research Fellow
Education PhD, Centre for DNA Fingerprinting and Diagnostics (CDFD)
Interests Signal transduction, stem cells and small RNA molecular biology
My primary research project will be on the dedifferentiation of cell types into stem cells. Visit again soon for more details.
|
| |
 |
|
Ming-Hsiang (Vicky) Sung Research Fellow
Education PhD in Molecular Microbiology and Immunology, U. of Southern California
Interests I want to understand the mechanisms of disease development and find better cures for them
I was trained in the field of molecular microbiology and immunology, specifically with HBV, HCV, HDV, HIV, Mycoplasma, Neisseria, Trypanosoma and a little gene therapy in human ES cells. My current project is to develop a novel strategy for studying signal transduction and therapy for diseases.
|
| |
 |
|
Tara
Thurber Lab Manager
Education B.S., University of
Maine-Orono
Interests Automation of high-throughput
screening of cDNA libraries via luminescence-based reporters
I spent my senior year studying the mitochondrial genome differences
between various orders of marine copepods and crustaceans, then
came to the Seed Lab as a research technician in the DNA Sequencing
Core, and chief operator of the Genetix Q-Bot. With the addition
of a Beckman-Coulter Biomek FX Core System, the Automation Core
was born, and now has a Cellomics ArrayScan II and Perkin-Elmer
TopCount NXT.
|
| |
 |
|
Huajun Wang Bioinformatics Specialist
Education PhD in Neurobiology, Columbia University
Interests Bioinformatics software development
My main interest is biological and chemical data management, analysis, and integration. After a bioinformatics postdoc training at Jackson Laboratory, I have mostly worked on bioinformatics software supporting the human genome project, SNP discovery and large-scale protein-protein interaction study. |
| |
 |
|
Guo Ling
Zhou Research Fellow
Education BSc and MS,
Huazhong Agricultural University, China; Ph D, Chinese Academy of
Medical Science and Peking Union Medical College, China.
Interests
Regulation network of eukaryotic gene expression, immunology, mouse
model for diseases
I obtained my Ph.D. studying the regulation of globin gene clusters
and the memory mechanism of epigenetic information during cell division
after I completed my B.Sc. and M.S., majoring in crop genetics and breeding.
I joined the Seed lab in October 2005 because I am interested in chromosomal
engineering and developing new approaches for creating mouse models
used in the study of immunology. |
|
