Ennamorati M, Vasudevan C, Clerkin K, Halvorsen S, Verma S, Ibrahim S, Prosper S, Porter C, Yeliseyev V, Kim M, Gardecki J, Sassi S, Tearney G, Cherayil BJ, Bry L, Seed B, Jain N Intestinal microbes influence development of thymic lymphocytes in early life. Proc Natl Acad Sci U S A. 2020;117(5):2570-2578 - PMID: 31964813 - PMCID: PMC7007548 - DOI: 10.1073/pnas.1915047117

Dong D, Zhou H, Na SY, Niedra R, Peng Y, Wang H, Seed B, Zhou GL GPR108, an NF-κB activator suppressed by TIRAP, negatively regulates TLR-triggered immune responses. PLoS One. 2018;13(10):e0205303 - PMID: 30332431 - PMCID: PMC6192633 - DOI: 10.1371/journal.pone.0205303

Datta S, Seed B Influence of multiplicative stochastic variation on translational elongation rates. PLoS One. 2018;13(1):e0191152 - PMID: 29351322 - PMCID: PMC5774726 - DOI: 10.1371/journal.pone.0191152

Davidson D, Zhong MC, Pandolfi PP, Bolland S, Xavier RJ, Seed B, Li X, Gu H, Veillette A The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors. Cell Rep. 2016;17(10):2776-2788 - PMID: 27926878 - PMCID: PMC5656005 - DOI: 10.1016/j.celrep.2016.11.035

Singhal PK, Sassi S, Lan L, Au P, Halvorsen SC, Fukumura D, Jain RK, Seed B Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity. Proc Natl Acad Sci U S A. 2016;113(1):122-7 - PMID: 26699463 - PMCID: PMC4711836 - DOI: 10.1073/pnas.1522401112

Draberova L, Bugajev V, Potuckova L, Halova I, Bambouskova M, Polakovicova I, Xavier RJ, Seed B, Draber P Transmembrane adaptor protein PAG/CBP is involved in both positive and negative regulation of mast cell signaling. Mol Cell Biol. 2014;34(23):4285-300 - PMID: 25246632 - PMCID: PMC4248753 - DOI: 10.1128/MCB.00983-14

Luft C, Freeman J, Elliott D, Al-Tamimi N, Kriston-Vizi J, Heintze J, Lindenschmidt I, Seed B, Ketteler R Application of Gaussia luciferase in bicistronic and non-conventional secretion reporter constructs. BMC Biochem. 2014;15(1):14 - PMID: 25007711 - PMCID: PMC4099409 - DOI: 10.1186/1471-2091-15-14

Zhou GL, Na SY, Niedra R, Seed B Deficits in receptor-mediated endocytosis and recycling in cells from mice bearing a disruption of the Gpr107 locus. J Cell Sci. 2014;127(Pt 18):3916-27 - PMID: 24849652 - DOI: 10.1242/jcs.135269

Zhou GL, Beloiartsev A, Yu B, Baron DM, Zhou W, Niedra R, Lu N, Tainsh LT, Zapol WM, Seed B, Bloch KD Deletion of the Murine Cytochrome P450 Cyp2j Locus by Fused BAC-Mediated Recombination Identifies a Role for Cyp2j in the Pulmonary Vascular Response to Hypoxia. PLoS Genet. 2013;9(11):e1003950 - PMID: 24278032 - PMCID: PMC3836722 - DOI: 10.1371/journal.pgen.1003950

Freeman J, Kriston-Vizi J, Seed B, Ketteler R A High-content Imaging Workflow to Study Grb2 Signaling Complexes by Expression Cloning. J Vis Exp. 2012;(68):ePub - PMID: 23150065 - PMCID: PMC3499067 - DOI: 10.3791/4382

Freeman J, Kriston-Vizi J, Seed B, Ketteler R A high-content imaging workflow to study Grb2 signaling complexes by expression cloning. J Vis Exp. 2012;(68):ePub - PMID: 23150065 - PMCID: PMC3499067 - DOI: 10.3791/4382

Cho JL, Roche MI, Sandall B, Brass AL, Seed B, Xavier RJ, Medoff BD Enhanced Tim3 Activity Improves Survival after Influenza Infection. J Immunol. 2012;189(6):2879-89 - PMID: 22875804 - PMCID: PMC3436990 - DOI: 10.4049/jimmunol.1102483

Cho JL, Roche MI, Sandall B, Brass AL, Seed B, Xavier RJ, Medoff BD Enhanced Tim3 activity improves survival after influenza infection. J Immunol. 2012;189(6):2879-89 - PMID: 22875804 - PMCID: PMC3436990 - DOI: 10.4049/jimmunol.1102483

Lindquist S, Karitkina D, Langnaese K, Posevitz-Fejfar A, Schraven B, Xavier R, Seed B, Lindquist JA Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation. PLoS One. 2011;6(9):e23978 - PMID: 21915273 - PMCID: PMC3167820 - DOI: 10.1371/journal.pone.0023978

Xu B, Feng Y, Cheng H, Song Y, Lv B, Wu Y, Wang C, Li S, Xu M, Du J, Peng K, Dong J, Zhang W, Zhang T, Zhu L, Ding H, Sheng Z, Welihinda A, Roberge JY, Seed B, Chen Y C-aryl glucosides substituted at the 4'-position as potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2011;21(15):4465-70 - PMID: 21737266 - DOI: 10.1016/j.bmcl.2011.06.032

Zhang W, Welihinda A, Mechanic J, Ding H, Zhu L, Lu Y, Deng Z, Sheng Z, Lv B, Chen Y, Roberge JY, Seed B, Wang YX EGT1442, a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA(1c) levels in db/db mice and prolongs the survival of stroke-prone rats. Pharmacol Res. 2011;63(4):284-93 - PMID: 21215314 - DOI: 10.1016/j.phrs.2011.01.001

Kim H, Seed B The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3. Nat Immunol. 2010;11(8):743-50 - PMID: 20581830 - PMCID: PMC3050627 - DOI: 10.1038/ni.1897

Mashima R, Honda K, Yang Y, Morita Y, Inoue A, Arimura S, Nishina H, Ema H, Nakauchi H, Seed B, Oda H, Yamanashi Y Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma. Lab Invest. 2010;90(9):1357-64 - PMID: 20548287 - DOI: 10.1038/labinvest.2010.121

Lv B, Feng Y, Dong J, Xu M, Xu B, Zhang W, Sheng Z, Welihinda A, Seed B, Chen Y Conformationally constrained spiro C-arylglucosides as potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors. ChemMedChem. 2010;5(6):827-31 - PMID: 20414917 - DOI: 10.1002/cmdc.201000051

Westerberg LS, Meelu P, Baptista M, Eston MA, Adamovich DA, Cotta-de-Almeida V, Seed B, Rosen MK, Vandenberghe P, Thrasher AJ, Klein C, Alt FW, Snapper SB Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes. J Exp Med. 2010;207(6):1145-52 - PMID: 20513746 - PMCID: PMC2882832 - DOI: 10.1084/jem.20091245

Xu B, Feng Y, Lv B, Xu G, Zhang L, Du J, Peng K, Xu M, Dong J, Zhang W, Zhang T, Zhu L, Ding H, Sheng Z, Welihinda A, Seed B, Chen Y ortho-Substituted C-aryl glucosides as highly potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors. Bioorg Med Chem. 2010;18(12):4422-32 - PMID: 20576578 - DOI: 10.1016/j.bmc.2010.04.088

Ketteler R, Tomov V, Neunkirchner A, Xie Q, Pickl WF, Seed B Host-encoded reporters for the detection and purification of multiple enveloped viruses. J Virol Methods. 2010;167(2):178-85 - PMID: 20399809 - PMCID: PMC2916077 - DOI: 10.1016/j.jviromet.2010.04.002

Kueng HJ, Manta C, Haiderer D, Leb VM, Schmetterer KG, Neunkirchner A, Byrne RA, Scheinecker C, Steinberger P, Seed B, Pickl WF Fluorosomes: a convenient new reagent to detect and block multivalent and complex receptor-ligand interactions. FASEB J. 2010;24(5):1572-82 - PMID: 20056716 - PMCID: PMC2879947 - DOI: 10.1096/fj.09-137281

Lv B, Xu B, Feng Y, Peng K, Xu G, Du J, Zhang L, Zhang W, Zhang T, Zhu L, Ding H, Sheng Z, Welihinda A, Seed B, Chen Y Exploration of O-spiroketal C-arylglucosides as novel and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors. Bioorg Med Chem Lett. 2009;19(24):6877-81 - PMID: 19896374 - DOI: 10.1016/j.bmcl.2009.10.088

Xu B, Lv B, Feng Y, Xu G, Du J, Welihinda A, Sheng Z, Seed B, Chen Y O-Spiro C-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors. Bioorg Med Chem Lett. 2009;19(19):5632-5 - PMID: 19700318 - DOI: 10.1016/j.bmcl.2009.08.030

Leb VM, Jahn-Schmid B, Kueng HJ, Schmetterer KG, Haiderer D, Neunkirchner A, Fischer GF, Hartl A, Thalhamer J, Steinberger P, Bohle B, Seed B, Pickl WF Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules. J Allergy Clin Immunol. 2009;124(1):121-8 - PMID: 19500826 - DOI: 10.1016/j.jaci.2009.04.008

Luong MX, Tam J, Lin Q, Hagendoorn J, Moore KJ, Padera TP, Seed B, Fukumura D, Kucherlapati R, Jain RK Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice. J Cell Physiol. 2009;219(2):430-7 - PMID: 19170073 - PMCID: PMC2665001 - DOI: 10.1002/jcp.21686

Adams JC, Seed B, Lu N, Landry A, Xavier RJ Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress. Neuroscience. 2009;160(2):530-9 - PMID: 19285117 - PMCID: PMC2673023 - DOI: 10.1016/j.neuroscience.2009.02.073

Adams JC, Seed B, Lu N, Landry A, Xavier RJ Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress. Neuroscience. 2009;160(2):530-9 - PMID: 19285117 - PMCID: PMC2673023 - DOI: 10.1016/j.neuroscience.2009.02.073

Spandidos A, Wang X, Wang H, Dragnev S, Thurber T, Seed B A comprehensive collection of experimentally validated primers for Polymerase Chain Reaction quantitation of murine transcript abundance. BMC Genomics. 2008;9:633 - PMID: 19108745 - PMCID: PMC2631021 - DOI: 10.1186/1471-2164-9-633

Thomson CE, McCulloch M, Sorenson A, Barnett SC, Seed BV, Griffiths IR, McLaughlin M Myelinated, synapsing cultures of murine spinal cord--validation as an in vitro model of the central nervous system. Eur J Neurosci. 2008;28(8):1518-35 - PMID: 18793322 - PMCID: PMC2777255 - DOI: 10.1111/j.1460-9568.2008.06415.x

Ketteler R, Seed B Quantitation of autophagy by luciferase release assay. Autophagy. 2008;4(6):801-6 - PMID: 18641457 - PMCID: PMC2910585 - DOI: 10.4161/auto.6401

Seed B, Xavier R Spinophilin and the immune synapse. J Cell Biol. 2008;181(2):181-3 - PMID: 18411314 - PMCID: PMC2315665 - DOI: 10.1083/jcb.200803120

Ketteler R, Sun Z, Kovacs KF, He WW, Seed B A pathway sensor for genome-wide screens of intracellular proteolytic cleavage. Genome Biol. 2008;9(4):R64 - PMID: 18387192 - PMCID: PMC2643935 - DOI: 10.1186/gb-2008-9-4-r64

Schöbel S, Neumann S, Hertweck M, Dislich B, Kuhn PH, Kremmer E, Seed B, Baumeister R, Haass C, Lichtenthaler SF A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein. J Biol Chem. 2008;283(21):14257-68 - PMID: 18353773 - DOI: 10.1074/jbc.M801531200

Kueng HJ, Leb VM, Haiderer D, Raposo G, Thery C, Derdak SV, Schmetterer KG, Neunkirchner A, Sillaber C, Seed B, Pickl WF General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines. J Virol. 2007;81(16):8666-76 - PMID: 17537846 - PMCID: PMC1951353 - DOI: 10.1128/JVI.00682-07

Derdak SV, Kueng HJ, Leb VM, Neunkirchner A, Schmetterer KG, Bielek E, Majdic O, Knapp W, Seed B, Pickl WF Direct stimulation of T lymphocytes by immunosomes: virus-like particles decorated with T cell receptor/CD3 ligands plus costimulatory molecules. Proc Natl Acad Sci U S A. 2006;103(35):13144-9 - PMID: 16924110 - PMCID: PMC1559767 - DOI: 10.1073/pnas.0602283103

Rideout K, Seed B, Ostry A Putting food on the public health table: Making food security relevant to regional health authorities. Can J Public Health. 2006;97(3):233-6 - PMID: 16827415 - PMCID: PMC6976105 - DOI: 10.1007/BF03405593

Kuo WP, Liu F, Trimarchi J, Punzo C, Lombardi M, Sarang J, Whipple ME, Maysuria M, Serikawa K, Lee SY, McCrann D, Kang J, Shearstone JR, Burke J, Park DJ, Wang X, Rector TL, Ricciardi-Castagnoli P, Perrin S, Choi S, Bumgarner R, Kim JH, Short GF, Freeman MW, Seed B, Jensen R, Church GM, Hovig E, Cepko CL, Park P, Ohno-Machado L, Jenssen TK A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies. Nat Biotechnol. 2006;24(7):832-40 - PMID: 16823376 - DOI: 10.1038/nbt1217

Medoff BD, Seed B, Jackobek R, Zora J, Yang Y, Luster AD, Xavier R CARMA1 is critical for the development of allergic airway inflammation in a murine model of asthma. J Immunol. 2006;176(12):7272-7 - PMID: 16751370 - DOI: 10.4049/jimmunol.176.12.7272

Schöbel S, Neumann S, Seed B, Lichtenthaler SF Expression cloning screen for modifiers of amyloid precursor protein shedding. Int J Dev Neurosci. 2006;24(2-3):141-8 - PMID: 16446073 - DOI: 10.1016/j.ijdevneu.2005.11.003

Yang M, Hase H, Legarda-Addison D, Varughese L, Seed B, Ting AT B cell maturation antigen, the receptor for a proliferation-inducing ligand and B cell-activating factor of the TNF family, induces antigen presentation in B cells. J Immunol. 2005;175(5):2814-24 - PMID: 16116167 - DOI: 10.4049/jimmunol.175.5.2814

Ting A, Lichtenthaler S, Xavier R, Na SY, Rabizadeh S, Holmes T, Seed B Large-scale screens for cDNAs with in vivo activity. Novartis Found Symp. 2005;267:219-29; discussion 229-30 - PMID: 15999809

Iwasaki H, Mizuno S, Mayfield R, Shigematsu H, Arinobu Y, Seed B, Gurish MF, Takatsu K, Akashi K Identification of eosinophil lineage-committed progenitors in the murine bone marrow. J Exp Med. 2005;201(12):1891-7 - PMID: 15955840 - PMCID: PMC2212039 - DOI: 10.1084/jem.20050548

Xavier R, Seed B PDZ domains and the politics of polarity in lymphocytes. Immunity. 2005;22(6):655-6 - PMID: 15963778 - DOI: 10.1016/j.immuni.2005.06.003

Duda DG, Fukumura D, Munn LL, Booth MF, Brown EB, Huang P, Seed B, Jain RK Differential transplantability of tumor-associated stromal cells. Cancer Res. 2004;64(17):5920-4 - PMID: 15342367 - DOI: 10.1158/0008-5472.CAN-04-1268

Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH, Lloyd KC, Magnuson T, Moore MW, Nagy A, Pollock JD, Roses AD, Sands AT, Seed B, Skarnes WC, Snoddy J, Soriano P, Stewart DJ, Stewart F, Stillman B, Varmus H, Varticovski L, Verma IM, Vogt TF, von Melchner H, Witkowski J, Woychik RP, Wurst W, Yancopoulos GD, Young SG, Zambrowicz B The knockout mouse project. Nat Genet. 2004;36(9):921-4 - PMID: 15340423 - PMCID: PMC2716027 - DOI: 10.1038/ng0904-921

Xavier R, Rabizadeh S, Ishiguro K, Andre N, Ortiz JB, Wachtel H, Morris DG, Lopez-Ilasaca M, Shaw AC, Swat W, Seed B Discs large (Dlg1) complexes in lymphocyte activation. J Cell Biol. 2004;166(2):173-8 - PMID: 15263016 - PMCID: PMC2172307 - DOI: 10.1083/jcb.200309044

Rabizadeh S, Xavier RJ, Ishiguro K, Bernabeortiz J, Lopez-Ilasaca M, Khokhlatchev A, Mollahan P, Pfeifer GP, Avruch J, Seed B The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death. J Biol Chem. 2004;279(28):29247-54 - PMID: 15075335 - DOI: 10.1074/jbc.M401699200

Wang X, Seed B A PCR primer bank for quantitative gene expression analysis. Nucleic Acids Res. 2003;31(24):e154 - PMID: 14654707 - PMCID: PMC291882 - DOI: 10.1093/nar/gng154

Lichtenthaler SF, Dominguez DI, Westmeyer GG, Reiss K, Haass C, Saftig P, De Strooper B, Seed B The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1. J Biol Chem. 2003;278(49):48713-9 - PMID: 14507929 - DOI: 10.1074/jbc.M303861200

Brown E, McKee T, diTomaso E, Pluen A, Seed B, Boucher Y, Jain RK Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation. Nat Med. 2003;9(6):796-800 - PMID: 12754503 - DOI: 10.1038/nm879

Wang X, Seed B Selection of oligonucleotide probes for protein coding sequences. Bioinformatics. 2003;19(7):796-802 - PMID: 12724288 - DOI: 10.1093/bioinformatics/btg086

Yang Y, Seed B Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes. Nat Biotechnol. 2003;21(4):447-51 - PMID: 12627171 - DOI: 10.1038/nbt803

Afting M, Stock UA, Nasseri B, Pomerantseva I, Seed B, Vacanti JP Efficient and stable retroviral transfection of ovine endothelial cells with green fluorescent protein for cardiovascular tissue engineering. Tissue Eng. 2003;9(1):137-41 - PMID: 12625962 - DOI: 10.1089/107632703762687618

Khokhlatchev A, Rabizadeh S, Xavier R, Nedwidek M, Chen T, Zhang XF, Seed B, Avruch J Identification of a novel Ras-regulated proapoptotic pathway. Curr Biol. 2002;12(4):253-65 - PMID: 11864565 - DOI: 10.1016/s0960-9822(02)00683-8

Yang Y, Kuang Y, Montes De Oca R, Hays T, Moreau L, Lu N, Seed B, D'Andrea AD Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9. Blood. 2001;98(12):3435-40 - PMID: 11719385 - DOI: 10.1182/blood.v98.12.3435

Randow F, Seed B Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability. Nat Cell Biol. 2001;3(10):891-6 - PMID: 11584270 - DOI: 10.1038/ncb1001-891

Fukumura D, Xu L, Chen Y, Gohongi T, Seed B, Jain RK Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo. Cancer Res. 2001;61(16):6020-4 - PMID: 11507045

Pickl WF, Pimentel-Muiños FX, Seed B Lipid rafts and pseudotyping. J Virol. 2001;75(15):7175-83 - PMID: 11435598 - PMCID: PMC114446 - DOI: 10.1128/JVI.75.15.7175-7183.2001

Bültmann A, Muranyi W, Seed B, Haas J Identification of two sequences in the cytoplasmic tail of the human immunodeficiency virus type 1 envelope glycoprotein that inhibit cell surface expression. J Virol. 2001;75(11):5263-76 - PMID: 11333908 - PMCID: PMC114932 - DOI: 10.1128/JVI.75.11.5263-5276.2001

Seed B Silanizing glassware. Curr Protoc Immunol. 2001;Appendix 3:Appendix 3K - PMID: 18432662 - DOI: 10.1002/0471142735.ima03ks21

Seed B Silanizing glassware. Curr Protoc Protein Sci. 2001;Appendix 3:Appendix 3E - PMID: 18429072 - DOI: 10.1002/0471140864.psa03es13

Seed B Silanizing glassware. Curr Protoc Mol Biol. 2001;Appendix 3:Appendix 3B - PMID: 18265032 - DOI: 10.1002/0471142727.mba03bs28

Seed B Silanizing glassware. Curr Protoc Cell Biol. 2001;Appendix 3:Appendix 3E - PMID: 18228287 - DOI: 10.1002/0471143030.cba03es08

Holler N, Zaru R, Micheau O, Thome M, Attinger A, Valitutti S, Bodmer JL, Schneider P, Seed B, Tschopp J Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol. 2000;1(6):489-95 - PMID: 11101870 - DOI: 10.1038/82732

Wang X, Zeng W, Murakawa M, Freeman MW, Seed B Episomal segregation of the adenovirus enhancer sequence by conditional genome rearrangement abrogates late viral gene expression. J Virol. 2000;74(23):11296-303 - PMID: 11070029 - PMCID: PMC113234 - DOI: 10.1128/jvi.74.23.11296-11303.2000

Wang X, Zeng W, Murakawa M, Freeman MW, Seed B Episomal segregation of the adenovirus enhancer sequence by conditional genome rearrangement abrogates late viral gene expression. J Virol. 2000;74(23):11296-303 - PMID: 11070029 - PMCID: PMC113234 - DOI: 10.1128/jvi.74.23.11296-11303.2000

Beck PL, Xavier R, Lu N, Nanda NN, Dinauer M, Podolsky DK, Seed B Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice. Gastroenterology. 2000;119(3):699-705 - PMID: 10982764 - DOI: 10.1053/gast.2000.16497

Pimentel-Muiños FX, Seed B Regulated commitment of TNF receptor signaling: a molecular switch for death or activation. Immunity. 1999;11(6):783-93 - PMID: 10626900 - DOI: 10.1016/s1074-7613(00)80152-1

Izumi KM, Cahir McFarland ED, Ting AT, Riley EA, Seed B, Kieff ED The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activation. Mol Cell Biol. 1999;19(8):5759-67 - PMID: 10409763 - PMCID: PMC84426 - DOI: 10.1128/mcb.19.8.5759

Xavier R, Seed B Membrane compartmentation and the response to antigen. Curr Opin Immunol. 1999;11(3):265-9 - PMID: 10375560 - DOI: 10.1016/s0952-7915(99)80043-0

Fukumura D, Xavier R, Sugiura T, Chen Y, Park EC, Lu N, Selig M, Nielsen G, Taksir T, Jain RK, Seed B Tumor induction of VEGF promoter activity in stromal cells. Cell. 1998;94(6):715-25 - PMID: 9753319 - DOI: 10.1016/s0092-8674(00)81731-6

Seed B PPARgamma and colorectal carcinoma: conflicts in a nuclear family. Nat Med. 1998;4(9):1004-5 - PMID: 9734386 - DOI: 10.1038/1990

Adams JC, Seed B, Lawler J Muskelin, a novel intracellular mediator of cell adhesive and cytoskeletal responses to thrombospondin-1. EMBO J. 1998;17(17):4964-74 - PMID: 9724633 - PMCID: PMC1170825 - DOI: 10.1093/emboj/17.17.4964

Xavier R, Brennan T, Li Q, McCormack C, Seed B Membrane compartmentation is required for efficient T cell activation. Immunity. 1998;8(6):723-32 - PMID: 9655486 - DOI: 10.1016/s1074-7613(00)80577-4

André S, Seed B, Eberle J, Schraut W, Bültmann A, Haas J Increased immune response elicited by DNA vaccination with a synthetic gp120 sequence with optimized codon usage. J Virol. 1998;72(2):1497-503 - PMID: 9445053 - PMCID: PMC124631 - DOI: 10.1128/JVI.72.2.1497-1503.1998

Jiang C, Ting AT, Seed B PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature. 1998;391(6662):82-6 - PMID: 9422509 - DOI: 10.1038/34184

Kolanus W, Seed B Integrins and inside-out signal transduction: converging signals from PKC and PIP3. Curr Opin Cell Biol. 1997;9(5):725-31 - PMID: 9330877 - DOI: 10.1016/s0955-0674(97)80127-5

Ting AT, Pimentel-Muiños FX, Seed B RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis. EMBO J. 1996;15(22):6189-96 - PMID: 8947041 - PMCID: PMC452440

Kolanus W, Nagel W, Schiller B, Zeitlmann L, Godar S, Stockinger H, Seed B Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule. Cell. 1996;86(2):233-42 - PMID: 8706128 - DOI: 10.1016/s0092-8674(00)80095-1

Haas J, Park EC, Seed B Codon usage limitation in the expression of HIV-1 envelope glycoprotein. Curr Biol. 1996;6(3):315-24 - PMID: 8805248 - DOI: 10.1016/s0960-9822(02)00482-7

Greenberg S, Chang P, Wang DC, Xavier R, Seed B Clustered syk tyrosine kinase domains trigger phagocytosis. Proc Natl Acad Sci U S A. 1996;93(3):1103-7 - PMID: 8577722 - PMCID: PMC40038 - DOI: 10.1073/pnas.93.3.1103

Li Z, Otevrel T, Gao Y, Cheng HL, Seed B, Stamato TD, Taccioli GE, Alt FW The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. Cell. 1995;83(7):1079-89 - PMID: 8548796 - DOI: 10.1016/0092-8674(95)90135-3

Pouyani T, Seed B PSGL-1 recognition of P-selectin is controlled by a tyrosine sulfation consensus at the PSGL-1 amino terminus. Cell. 1995;83(2):333-43 - PMID: 7585950 - DOI: 10.1016/0092-8674(95)90174-4

Seed B Developments in expression cloning. Curr Opin Biotechnol. 1995;6(5):567-73 - PMID: 7579669 - DOI: 10.1016/0958-1669(95)80094-8

Stanger BZ, Leder P, Lee TH, Kim E, Seed B RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell. 1995;81(4):513-23 - PMID: 7538908 - DOI: 10.1016/0092-8674(95)90072-1

Seed B, Kolanus W, Romeo C, Xavier R Nonreceptor tyrosine kinases in aggregation-mediated cell activation. Adv Exp Med Biol. 1995;365:111-9 - PMID: 7887297 - DOI: 10.1007/978-1-4899-0987-9_12

Seed B Initiation of signal transduction by receptor aggregation: role of nonreceptor tyrosine kinases. Semin Immunol. 1995;7(1):3-11 - PMID: 7612893 - DOI: 10.1016/1044-5323(95)90002-0

Seed B Making agonists of antagonists. Chem Biol. 1994;1(3):125-9 - PMID: 9383381 - DOI: 10.1016/1074-5521(94)90001-9

Loh C, Romeo C, Seed B, Bruder JT, Rapp U, Rao A Association of Raf with the CD3 delta and gamma chains of the T cell receptor-CD3 complex. J Biol Chem. 1994;269(12):8817-25 - PMID: 8132616

Koch AE, Nickoloff BJ, Holgersson J, Seed B, Haines GK, Burrows JC, Leibovich SJ 4A11, a monoclonal antibody recognizing a novel antigen expressed on aberrant vascular endothelium. Upregulation in an in vivo model of contact dermatitis. Am J Pathol. 1994;144(2):244-59 - PMID: 8311112 - PMCID: PMC1887152

Romeo C, Kolanus W, Amiot M, Seed B Activation of immune system effector function by T-cell or Fc receptor intracellular domains. Cold Spring Harb Symp Quant Biol. 1993;57:117-25 - PMID: 1339650 - DOI: 10.1101/sqb.1992.057.01.015

Kolanus W, Romeo C, Seed B T cell activation by clustered tyrosine kinases. Cell. 1993;74(1):171-83 - PMID: 8334702 - DOI: 10.1016/0092-8674(93)90304-9

Langner KD, Niedrig M, Fultz P, Anderson D, Reiner G, Repke H, Gelderblom H, Seed B, Hilfenhaus J, Zettlmeissl G Antiviral effects of different CD4-immunoglobulin constructs against HIV-1 and SIV: immunological characterization, pharmacokinetic data and in vivo experiments. Arch Virol. 1993;130(1-2):157-70 - PMID: 8503781 - DOI: 10.1007/BF01319004

Kolanus W, Romeo C, Seed B Lineage-independent activation of immune system effector function by myeloid Fc receptors. EMBO J. 1992;11(13):4861-8 - PMID: 1464313 - PMCID: PMC556962 - DOI: 10.1002/j.1460-2075.1992.tb05592.x

Seed B Marked by a mucin. Curr Biol. 1992;2(9):457-9 - PMID: 15335892 - DOI: 10.1016/0960-9822(92)90647-s

Tanaka T, Camerini D, Seed B, Torimoto Y, Dang NH, Kameoka J, Dahlberg HN, Schlossman SF, Morimoto C Cloning and functional expression of the T cell activation antigen CD26. J Immunol. 1992;149(2):481-6 - PMID: 1352530

Romeo C, Amiot M, Seed B Sequence requirements for induction of cytolysis by the T cell antigen/Fc receptor zeta chain. Cell. 1992;68(5):889-97 - PMID: 1547489 - DOI: 10.1016/0092-8674(92)90032-8

Dürkop H, Latza U, Hummel M, Eitelbach F, Seed B, Stein H Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease. Cell. 1992;68(3):421-7 - PMID: 1310894 - DOI: 10.1016/0092-8674(92)90180-k

Simmons DL, Satterthwaite AB, Tenen DG, Seed B Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells. J Immunol. 1992;148(1):267-71 - PMID: 1370171

Camerini D, Walz G, Loenen WA, Borst J, Seed B The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family. J Immunol. 1991;147(9):3165-9 - PMID: 1655907

Aruffo A, Kolanus W, Walz G, Fredman P, Seed B CD62/P-selectin recognition of myeloid and tumor cell sulfatides. Cell. 1991;67(1):35-44 - PMID: 1717159 - DOI: 10.1016/0092-8674(91)90570-o

Aruffo A, Melnick MB, Linsley PS, Seed B The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins. J Exp Med. 1991;174(4):949-52 - PMID: 1919444 - PMCID: PMC2118957 - DOI: 10.1084/jem.174.4.949

Romeo C, Seed B Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides. Cell. 1991;64(5):1037-46 - PMID: 1900456 - DOI: 10.1016/0092-8674(91)90327-u

Stamenkovic I, Aruffo A, Amiot M, Seed B The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells. EMBO J. 1991;10(2):343-8 - PMID: 1991450 - PMCID: PMC452652 - DOI: 10.1002/j.1460-2075.1991.tb07955.x

Mayer B, Funke I, Seed B, Riethmüller G, Weiss E Expression of the CD6 T lymphocyte differentiation antigen in normal human brain. J Neuroimmunol. 1990;29(1-3):193-202 - PMID: 2211985 - DOI: 10.1016/0165-5728(90)90162-g

Walz G, Aruffo A, Kolanus W, Bevilacqua M, Seed B Recognition by ELAM-1 of the sialyl-Lex determinant on myeloid and tumor cells. Science. 1990;250(4984):1132-5 - PMID: 1701275 - DOI: 10.1126/science.1701275

Classon BJ, Williams AF, Willis AC, Seed B, Stamenkovic I The primary structure of the human leukocyte antigen CD37, a species homologue of the rat MRC OX-44 antigen. J Exp Med. 1990;172(3):1007 - PMID: 2388030 - PMCID: PMC2188538 - DOI: 10.1084/jem.172.3.1007

Inui S, Kaisho T, Kikutani H, Stamenkovic I, Seed B, Clark EA, Kishimoto T Identification of the intracytoplasmic region essential for signal transduction through a B cell activation molecule, CD40. Eur J Immunol. 1990;20(8):1747-53 - PMID: 1698631 - DOI: 10.1002/eji.1830200819

Aruffo A, Stamenkovic I, Melnick M, Underhill CB, Seed B CD44 is the principal cell surface receptor for hyaluronate. Cell. 1990;61(7):1303-13 - PMID: 1694723 - DOI: 10.1016/0092-8674(90)90694-a

Zettlmeissl G, Gregersen JP, Duport JM, Mehdi S, Reiner G, Seed B Expression and characterization of human CD4:immunoglobulin fusion proteins. DNA Cell Biol. 1990;9(5):347-53 - PMID: 2196903 - DOI: 10.1089/dna.1990.9.347

Sheen JY, Seed B Electrolyte gradient gels for DNA sequencing. Biotechniques. 1990;6(10):942-4 - PMID: 3273397

Stamenkovic I, Seed B The B-cell antigen CD22 mediates monocyte and erythrocyte adhesion. Nature. 1990;345(6270):74-7 - PMID: 1691828 - DOI: 10.1038/345074a0

Kurnit DM, Seed B Improved genetic selection for screening bacteriophage libraries by homologous recombination in vivo. Proc Natl Acad Sci U S A. 1990;87(8):3166-9 - PMID: 2183225 - PMCID: PMC53855 - DOI: 10.1073/pnas.87.8.3166

Camerini D, Seed B A CD4 domain important for HIV-mediated syncytium formation lies outside the virus binding site. Cell. 1990;60(5):747-54 - PMID: 2107024 - DOI: 10.1016/0092-8674(90)90089-w

Camerini D, James SP, Stamenkovic I, Seed B Leu-8/TQ1 is the human equivalent of the Mel-14 lymph node homing receptor. Nature. 1989;342(6245):78-82 - PMID: 2509939 - DOI: 10.1038/342078a0

Micklem K, Rigney E, Cordell J, Simmons D, Stross P, Turley H, Seed B, Mason D A human macrophage-associated antigen (CD68) detected by six different monoclonal antibodies. Br J Haematol. 1989;73(1):6-11 - PMID: 2803980 - DOI: 10.1111/j.1365-2141.1989.tb00210.x

Aruffo A, Seed B Expression of cDNA clones encoding the thymocyte antigens CD1a, b, c demonstrates a hierarchy of exclusion in fibroblasts. J Immunol. 1989;143(5):1723-30 - PMID: 2701945

Oquendo P, Hundt E, Lawler J, Seed B CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Cell. 1989;58(1):95-101 - PMID: 2473841 - DOI: 10.1016/0092-8674(89)90406-6

Stamenkovic I, Clark EA, Seed B A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. EMBO J. 1989;8(5):1403-10 - PMID: 2475341 - PMCID: PMC400967 - DOI: 10.1002/j.1460-2075.1989.tb03521.x

Classon BJ, Williams AF, Willis AC, Seed B, Stamenkovic I The primary structure of the human leukocyte antigen CD37, a species homologue of the rat MRC OX-44 antigen. J Exp Med. 1989;169(4):1497-502 - PMID: 2466944 - PMCID: PMC2189247 - DOI: 10.1084/jem.169.4.1497

Stamenkovic I, Amiot M, Pesando JM, Seed B A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family. Cell. 1989;56(6):1057-62 - PMID: 2466575 - DOI: 10.1016/0092-8674(89)90638-7

Bevilacqua MP, Stengelin S, Gimbrone MA, Seed B Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science. 1989;243(4895):1160-5 - PMID: 2466335 - DOI: 10.1126/science.2466335

Huang HV, Little PF, Seed B Improved suppressor tRNA cloning vectors and plasmid-phage recombination. Biotechnology. 1989;10:269-83 - PMID: 3061517 - DOI: 10.1016/b978-0-409-90042-2.50020-9

Simmons DL, Tan S, Tenen DG, Nicholson-Weller A, Seed B Monocyte antigen CD14 is a phospholipid anchored membrane protein. Blood. 1989;73(1):284-9 - PMID: 2462937

Allen JM, Seed B Isolation and expression of functional high-affinity Fc receptor complementary DNAs. Science. 1989;243(4889):378-81 - PMID: 2911749 - DOI: 10.1126/science.2911749

Allen JM, Seed B Nucleotide sequence of three cDNAs for the human high affinity Fc receptor (FcRI). Nucleic Acids Res. 1988;16(24):11824 - PMID: 2974947 - PMCID: PMC339124 - DOI: 10.1093/nar/16.24.11824

Bierer BE, Greenstein JL, Sleckman B, Ratnofsky S, Peterson A, Seed B, Burakoff SJ Functional analysis of CD2, CD4, and CD8 in T-cell activation. Ann N Y Acad Sci. 1988;532:199-206 - PMID: 3052208 - DOI: 10.1111/j.1749-6632.1988.tb36338.x

Simmons D, Seed B Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells. J Immunol. 1988;141(8):2797-800 - PMID: 3139766

Stamenkovic I, Seed B CD19, the earliest differentiation antigen of the B cell lineage, bears three extracellular immunoglobulin-like domains and an Epstein-Barr virus-related cytoplasmic tail. J Exp Med. 1988;168(3):1205-10 - PMID: 2459292 - PMCID: PMC2189043 - DOI: 10.1084/jem.168.3.1205

Yamasaki K, Taga T, Hirata Y, Yawata H, Kawanishi Y, Seed B, Taniguchi T, Hirano T, Kishimoto T Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor. Science. 1988;241(4867):825-8 - PMID: 3136546 - DOI: 10.1126/science.3136546

Duguid JR, Rohwer RG, Seed B Isolation of cDNAs of scrapie-modulated RNAs by subtractive hybridization of a cDNA library. Proc Natl Acad Sci U S A. 1988;85(15):5738-42 - PMID: 2456582 - PMCID: PMC281836 - DOI: 10.1073/pnas.85.15.5738

Peterson A, Seed B Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4. Cell. 1988;54(1):65-72 - PMID: 2454749 - DOI: 10.1016/0092-8674(88)90180-8

Seed B, Sheen JY A simple phase-extraction assay for chloramphenicol acyltransferase activity. Gene. 1988;67(2):271-7 - PMID: 3169576 - DOI: 10.1016/0378-1119(88)90403-9

Simmons D, Seed B The Fc gamma receptor of natural killer cells is a phospholipid-linked membrane protein. Nature. 1988;333(6173):568-70 - PMID: 2967436 - DOI: 10.1038/333568a0

Stamenkovic I, Seed B Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III integral membrane protein. J Exp Med. 1988;167(6):1975-80 - PMID: 3260267 - PMCID: PMC2189672 - DOI: 10.1084/jem.167.6.1975

Stengelin S, Stamenkovic I, Seed B Isolation of cDNAs for two distinct human Fc receptors by ligand affinity cloning. EMBO J. 1988;7(4):1053-9 - PMID: 3402431 - PMCID: PMC454434 - DOI: 10.1002/j.1460-2075.1988.tb02913.x

Simmons D, Makgoba MW, Seed B ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM. Nature. 1988;331(6157):624-7 - PMID: 3340213 - DOI: 10.1038/331624a0

Bierer BE, Peterson A, Barbosa J, Seed B, Burakoff SJ Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation. Proc Natl Acad Sci U S A. 1988;85(4):1194-8 - PMID: 2448792 - PMCID: PMC279733 - DOI: 10.1073/pnas.85.4.1194

Seed B An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2. Nature. 1987;329(6142):840-2 - PMID: 3313052 - DOI: 10.1038/329840a0

Peterson A, Seed B Monoclonal antibody and ligand binding sites of the T cell erythrocyte receptor (CD2). Nature. 1987;329(6142):842-6 - PMID: 2444890 - DOI: 10.1038/329842a0

Aruffo A, Seed B Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system. Proc Natl Acad Sci U S A. 1987;84(23):8573-7 - PMID: 2825196 - PMCID: PMC299587 - DOI: 10.1073/pnas.84.23.8573

Aruffo A, Seed B Molecular cloning of two CD7 (T-cell leukemia antigen) cDNAs by a COS cell expression system. EMBO J. 1987;6(11):3313-6 - PMID: 3501369 - PMCID: PMC553785 - DOI: 10.1002/j.1460-2075.1987.tb02651.x

Sleckman BP, Peterson A, Jones WK, Foran JA, Greenstein JL, Seed B, Burakoff SJ Expression and function of CD4 in a murine T-cell hybridoma. Nature. 1987;328(6128):351-3 - PMID: 3037388 - DOI: 10.1038/328351a0

Lutz CT, Hollifield WC, Seed B, Davie JM, Huang HV Syrinx 2A: an improved lambda phage vector designed for screening DNA libraries by recombination in vivo. Proc Natl Acad Sci U S A. 1987;84(13):4379-83 - PMID: 2955406 - PMCID: PMC305092 - DOI: 10.1073/pnas.84.13.4379

Seed B, Aruffo A Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure. Proc Natl Acad Sci U S A. 1987;84(10):3365-9 - PMID: 2437578 - PMCID: PMC304871 - DOI: 10.1073/pnas.84.10.3365

Levinson A, Silver D, Seed B Minimal size plasmids containing an M13 origin for production of single-strand transducing particles. J Mol Appl Genet. 1985;2(6):507-17 - PMID: 6099398

Seed B A comparison of postmigration and migration-coupled mismatch correction mechanisms for branch migration-mediated gene conversion. Genetics. 1984;106(3):549-67 - PMID: 6706113 - PMCID: PMC1224256 - DOI: 10.1093/genetics/106.3.549

Little PF, Treisman R, Bierut L, Seed B, Maniatis T Plasmid vectors for the rapid isolation and transcriptional analysis of human beta-globin gene alleles. Mol Biol Med. 1983;1(5):473-88 - PMID: 6094959

Seed B Purification of genomic sequences from bacteriophage libraries by recombination and selection in vivo. Nucleic Acids Res. 1983;11(8):2427-45 - PMID: 6856467 - PMCID: PMC325894 - DOI: 10.1093/nar/11.8.2427

Seed B Theoretical study of the fraction of a long-chain DNA that can be incorporated in a recombinant DNA partial-digest library. Biopolymers. 1982;21(9):1793-810 - PMID: 7126756 - DOI: 10.1002/bip.360210909

Seed B, Parker RC, Davidson N Representation of DNA sequences in recombinant DNA libraries prepared by restriction enzyme partial digestion. Gene. 1982;19(2):201-9 - PMID: 6293929 - DOI: 10.1016/0378-1119(82)90007-5

Seed B Diazotizable arylamine cellulose papers for the coupling and hybridization of nucleic acids. Nucleic Acids Res. 1982;10(5):1799-810 - PMID: 7071022 - PMCID: PMC320567 - DOI: 10.1093/nar/10.5.1799

Parker RC, Seed B Two-dimensional agarose gel electrophoresis "SeaPlaque" agarose dimension. Methods Enzymol. 1980;65(1):358-63 - PMID: 6246359