Director, Center for Computational and Integrative Biology
Brian Seed is a Professor of Genetics at Harvard and Director of the Center for Computational and Integrative Biology at the Massachusetts General Hospital (MGH). He obtained his B.S. and Ph.D. degrees from the California Institute of Technology. Prof. Seed is the author of a number of publications on genetics and molecular biology with an emphasis on the development of methods and technology. His early efforts to develop of genetic selections for transiently expressed genes led to the identification of cDNAs encoding the majority of the then-recognized lineage antigens of the immune system. In addition he has made several contributions to the understanding of the mechanisms of T cell activation. His work on immunoglobulin fusion proteins led to the identification of several co-receptors and ligands and laid the basis for the development of several therapeutic fusion proteins. He co-founded several biotech companies including Connetics, Edge Biosystems, Phylos, Egret Pharma (Shanghai) Ltd. and Theracos, Inc. and has served on the advisory boards for Hoechst/Aventis, Medigene A.G., St. Jude Children’s Research Hospital, Phylos and New Leaf Ventures.