• Lo J, Rosenberg ES, Fitzgerald ML, Bazner SB, Ihenachor EJ, Hawxhurst V, Borkowska AH, Wei J, Zimmerman CO, Burdo TH, Williams KC, Freeman MW, Grinspoon SK High-density lipoprotein-mediated cholesterol efflux capacity is improved by treatment with antiretroviral therapy in acute human immunodeficiency virus infection. Open Forum Infect Dis. 2014;1(3):ofu108 - PMID: 25734176 - PMCID: PMC4324225 - DOI: 10.1093/ofid/ofu108

  • Haller JF, Cavallaro P, Hernandez NJ, Dolat L, Soscia SJ, Welti R, Grabowski GA, Fitzgerald ML, Freeman MW Endogenous ?-glucocerebrosidase activity in Abca12-/-epidermis elevates ceramide levels after topical lipid application but does not restore barrier function. J Lipid Res. 2014;55(3):493-503 - PMID: 24293640 - PMCID: PMC3934733 - DOI: 10.1194/jlr.M044941

  • Best SR, Friedman AD, Landau-Zemer T, Barbu AM, Burns JA, Freeman MW, Halvorsen YD, Hillman RE, Zeitels SM Safety and dosing of bevacizumab (avastin) for the treatment of recurrent respiratory papillomatosis. Ann Otol Rhinol Laryngol. 2012;121(9):587-93 - PMID: 23012897 - DOI: 10.1177/000348941212100905

  • Moore KJ, Freeman MW Embryonal Stem (ES) Cell-Derived Macrophages : A Cellular System that Facilitates the Genetic Dissection of Macrophage Function. Methods Mol Med. 2011;30:343-55 - PMID: 21341038 - DOI: 10.1385/1-59259-247-3:343

  • Moore KJ, Freeman MW Targeting Innate Immunity for CV Benefit. Drug Discov Today Ther Strateg. 2011;5(1):15-23 - PMID: 19430537 - PMCID: PMC2678718 - DOI: 10.1016/j.ddstr.2008.05.007

  • Freeman MW, Dervan AP The path from bench to bedside: considerations before starting the journey. J Investig Med. 2011;59(5):746-51 - PMID: 21441830 - PMCID: PMC4255460 - DOI: 10.2310/JIM.0b013e3182160d70

  • Kim WS, Hill AF, Fitzgerald ML, Freeman MW, Evin G, Garner B Wild type and Tangier disease ABCA1 mutants modulate cellular amyloid-? production independent of cholesterol efflux activity. J Alzheimers Dis. 2011;27(2):441-52 - PMID: 21860089 - DOI: 10.3233/JAD-2011-110521

  • Zeitels SM, Barbu AM, Landau-Zemer T, Lopez-Guerra G, Burns JA, Friedman AD, Freeman MW, Halvorsen YD, Hillman RE Local injection of bevacizumab (Avastin) and angiolytic KTP laser treatment of recurrent respiratory papillomatosis of the vocal folds: a prospective study. Ann Otol Rhinol Laryngol. 2011;120(10):627-34 - PMID: 22097147 - DOI: 10.1177/000348941112001001

  • MW Freeman Lipoprotein Metabolism and the Treatment of Lipid Disorders, Chapter 42. In: DeGroot LJ and JL Jameson, eds. Endocrinology, 6th edition. 2010;:ePub

  • Haydock GS and MW Freeman Screening for hyperlipidemia. In: Goroll A and Mulley A, eds. . Primary Care Medicine, 6th Edition. 2009;:ePub

  • MW Freeman Approach to the patient with hypercholesterolemia. In: Goroll A, May L, Mulley A, eds. Primary Care Medicine, 6th Edition. 2009;:ePub

  • M Freeman, Consultant editor, 4th edition. Buckley, Rita What to do about high cholesterol. President and Fellows of Harvard College. Harvard Health Publications. 2009;:ePub

  • KJ Moore and MW Freeman Targeting innate immunity for CV benefit. Drug Discovery Today: Therapeutic Strategies. 2008;5:15-23

  • Tamehiro N, Zhou S, Okuhira K, Benita Y, Brown CE, Zhuang DZ, Latz E, Hornemann T, von Eckardstein A, Xavier RJ, Freeman MW, Fitzgerald ML SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter. Biochemistry. 2008;47(23):6138-47 - PMID: 18484747 - PMCID: PMC2504083 - DOI: 10.1021/bi800182t

  • Zuo Y, Zhuang DZ, Han R, Isaac G, Tobin JJ, McKee M, Welti R, Brissette JL, Fitzgerald ML, Freeman MW ABCA12 maintains the epidermal lipid permeability barrier by facilitating formation of ceramide linoleic esters. J Biol Chem. 2008;283(52):36624-35 - PMID: 18957418 - PMCID: PMC2605993 - DOI: 10.1074/jbc.M807377200

  • Kiss RS, Kavaslar N, Okuhira K, Freeman MW, Walter S, Milne RW, McPherson R, Marcel YL Genetic etiology of isolated low HDL syndrome: incidence and heterogeneity of efflux defects. Arterioscler Thromb Vasc Biol. 2007;27(5):1139-45 - PMID: 17303779 - DOI: 10.1161/ATVBAHA.106.137646

  • MW Freeman Statins, cholesterol, and the prevention of coronary heart disease. FASEB J. 2006;20(2):200-201

  • MW Freeman Lipid Disorders and Coronary Heart Disease. In: Runge, MS and Patterson, W Eds. . Molecular Medicine. 2006;:ePub

  • Freeman MW Statins, cholesterol, and the prevention of coronary heart disease. FASEB J. 2006;20(2):200-1 - PMID: 16449790 - DOI: 10.1096/fj.06-0202ufm

  • Moore KJ, Freeman MW Scavenger receptors in atherosclerosis: beyond lipid uptake. Arterioscler Thromb Vasc Biol. 2006;26(8):1702-11 - PMID: 16728653 - DOI: 10.1161/01.ATV.0000229218.97976.43

  • Kuo WP, Liu F, Trimarchi J, Punzo C, Lombardi M, Sarang J, Whipple ME, Maysuria M, Serikawa K, Lee SY, McCrann D, Kang J, Shearstone JR, Burke J, Park DJ, Wang X, Rector TL, Ricciardi-Castagnoli P, Perrin S, Choi S, Bumgarner R, Kim JH, Short GF, Freeman MW, Seed B, Jensen R, Church GM, Hovig E, Cepko CL, Park P, Ohno-Machado L, Jenssen TK A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies. Nat Biotechnol. 2006;24(7):832-40 - PMID: 16823376 - DOI: 10.1038/nbt1217

  • Laberge MA, Moore KJ, and MW Freeman. Atherosclerosis and innate immunity signaling. Annals of Medicine. 2005;37:130-140

  • Gilmore O’Neill and MW Freeman Tangier Disease and Neuropathy. In: Dyck, PJ and Thomas, PK, Eds. Peripheral Neuropathy 4th edition. 2005;:ePub

  • MW Freeman Approach to the patient with hypercholesterolemia. In: Goroll A, May L, Mulley A, eds. Primary Care Medicine, 5th Edition. 2005;:ePub

  • M Freeman, Consultant editor 3rd edition Junge C, Skerret PJ, and Emond, SD. What to do about high cholesterol. President and Fellows of Harvard College. Harvard Health Publications. 2005;:ePub

  • Jeyaseelan S, Chu HW, Young SK, Freeman MW, Worthen GS Distinct roles of pattern recognition receptors CD14 and Toll-like receptor 4 in acute lung injury. Infect Immun. 2005;73(3):1754-63 - PMID: 15731076 - PMCID: PMC1064978 - DOI: 10.1128/IAI.73.3.1754-1763.2005

  • Farnier M, Freeman MW, Macdonell G, Perevozskaya I, Davies MJ, Mitchel YB, Gumbiner B, Efficacy and safety of the coadministration of ezetimibe with fenofibrate in patients with mixed hyperlipidaemia. Eur Heart J. 2005;26(9):897-905 - PMID: 15781429 - DOI: 10.1093/eurheartj/ehi231

  • Laberge MA, Moore KJ, Freeman MW Atherosclerosis and innate immune signaling. Ann Med. 2005;37(2):130-40 - PMID: 16026120 - DOI: 10.1080/07853890510007304

  • Heller EA, Liu E, Tager AM, Sinha S, Roberts JD, Koehn SL, Libby P, Aikawa ER, Chen JQ, Huang P, Freeman MW, Moore KJ, Luster AD, Gerszten RE Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment. Circulation. 2005;112(4):578-86 - PMID: 16043658 - DOI: 10.1161/CIRCULATIONAHA.105.545616

  • Moore KJ, Kunjathoor VV, Koehn SL, Manning JJ, Tseng AA, Silver JM, McKee M, Freeman MW Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice. J Clin Invest. 2005;115(8):2192-201 - PMID: 16075060 - PMCID: PMC1180534 - DOI: 10.1172/JCI24061

  • Lee ML, Whitmore GA, Björkbacka H, Freeman MW Nonparametric methods for microarray data based on exchangeability and borrowed power. J Biopharm Stat. 2005;15(5):783-97 - PMID: 16078385 - DOI: 10.1081/BIP-200067778

  • Okuhira K, Fitzgerald ML, Sarracino DA, Manning JJ, Bell SA, Goss JL, Freeman MW Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux. J Biol Chem. 2005;280(47):39653-64 - PMID: 16192269 - DOI: 10.1074/jbc.M510187200

  • Lee ML, Gray RJ, Björkbacka H, Freeman MW Generalized rank tests for replicated microarray data. Stat Appl Genet Mol Biol. 2005;4:Article3 - PMID: 16646848 - DOI: 10.2202/1544-6115.1093

  • MW Freeman and Christine Junge Harvard Medical School Guide to Lowering your Cholesterol. 2005;:ePub

  • Chroni A, Liu T, Fitzgerald ML, Freeman MW, Zannis VI Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1. Biochemistry. 2004;43(7):2126-39 - PMID: 14967052 - DOI: 10.1021/bi035813p

  • Björkbacka H, Kunjathoor VV, Moore KJ, Koehn S, Ordija CM, Lee MA, Means T, Halmen K, Luster AD, Golenbock DT, Freeman MW Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways. Nat Med. 2004;10(4):416-21 - PMID: 15034566 - DOI: 10.1038/nm1008

  • Fitzgerald ML, Okuhira K, Short GF, Manning JJ, Bell SA, Freeman MW ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities. J Biol Chem. 2004;279(46):48477-85 - PMID: 15347662 - DOI: 10.1074/jbc.M409848200

  • Björkbacka H, Fitzgerald KA, Huet F, Li X, Gregory JA, Lee MA, Ordija CM, Dowley NE, Golenbock DT, Freeman MW The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades. Physiol Genomics. 2004;19(3):319-30 - PMID: 15367722 - DOI: 10.1152/physiolgenomics.00128.2004

  • Ricci R, Sumara G, Sumara I, Rozenberg I, Kurrer M, Akhmedov A, Hersberger M, Eriksson U, Eberli FR, Becher B, Borén J, Chen M, Cybulsky MI, Moore KJ, Freeman MW, Wagner EF, Matter CM, Lüscher TF Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis. Science. 2004;306(5701):1558-61 - PMID: 15567863 - DOI: 10.1126/science.1101909

  • Freeman MW, Moore KJ eLiXiRs for restraining inflammation. Nat Med. 2003;9(2):168-9 - PMID: 12563335 - DOI: 10.1038/nm0203-168

  • El Khoury JB, Moore KJ, Means TK, Leung J, Terada K, Toft M, Freeman MW, Luster AD CD36 mediates the innate host response to beta-amyloid. J Exp Med. 2003;197(12):1657-66 - PMID: 12796468 - PMCID: PMC2193948 - DOI: 10.1084/jem.20021546

  • Kim WS, Ordija CM, Freeman MW Activation of signaling pathways by putative scavenger receptor class A (SR-A) ligands requires CD14 but not SR-A. Biochem Biophys Res Commun. 2003;310(2):542-9 - PMID: 14521944 - DOI: 10.1016/j.bbrc.2003.09.049

  • MW Freeman The Treatment of Dyslipidemia: LDL Reduction and Beyond. In Endocrinology Rounds. 2002;1, Issue 8:ePub

  • Rosen ED, Hsu CH, Wang X, Sakai S, Freeman MW, Gonzalez FJ, Spiegelman BM C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway. Genes Dev. 2002;16(1):22-6 - PMID: 11782441 - PMCID: PMC155311 - DOI: 10.1101/gad.948702

  • Fitzgerald ML, Moore KJ, Freeman MW Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home. J Mol Med (Berl). 2002;80(5):271-81 - PMID: 12021839 - DOI: 10.1007/s00109-001-0318-y

  • Fitzgerald ML, Morris AL, Rhee JS, Andersson LP, Mendez AJ, Freeman MW Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I. J Biol Chem. 2002;277(36):33178-87 - PMID: 12084722 - DOI: 10.1074/jbc.M204996200

  • Moore KJ, El Khoury J, Medeiros LA, Terada K, Geula C, Luster AD, Freeman MW A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid. J Biol Chem. 2002;277(49):47373-9 - PMID: 12239221 - DOI: 10.1074/jbc.M208788200

  • Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V, Akira S, Kasper DL, Golenbock DT Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways. J Immunol. 2002;169(7):3970-7 - PMID: 12244198 - DOI: 10.4049/jimmunol.169.7.3970

  • Yang KK, Dorner BG, Merkel U, Ryffel B, Schütt C, Golenbock D, Freeman MW, Jack RS Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice. J Immunol. 2002;169(8):4475-80 - PMID: 12370383 - DOI: 10.4049/jimmunol.169.8.4475

  • Kunjathoor VV, Febbraio M, Podrez EA, Moore KJ, Andersson L, Koehn S, Rhee JS, Silverstein R, Hoff HF, Freeman MW Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages. J Biol Chem. 2002;277(51):49982-8 - PMID: 12376530 - DOI: 10.1074/jbc.M209649200

  • Moore KJ, Rosen ED, Fitzgerald ML, Randow F, Andersson LP, Altshuler D, Milstone DS, Mortensen RM, Spiegelman BM, Freeman MW The role of PPAR-gamma in macrophage differentiation and cholesterol uptake. Nat Med. 2001;7(1):41-7 - PMID: 11135614 - DOI: 10.1038/83328

  • Rigotti A, Freeman MW Manipulating intestinal cholesterol absorption and hepatic cholesterol and bile acid metabolism by activation of deorphanized nuclear receptors. Gastroenterology. 2001;120(4):1054-5 - PMID: 11231965 - DOI: 10.1016/s0016-5085(01)83919-6

  • Fitzgerald ML, Mendez AJ, Moore KJ, Andersson LP, Panjeton HA, Freeman MW ATP-binding cassette transporter A1 contains an NH2-terminal signal anchor sequence that translocates the protein's first hydrophilic domain to the exoplasmic space. J Biol Chem. 2001;276(18):15137-45 - PMID: 11328826 - DOI: 10.1074/jbc.m100474200

  • Bobryshev YV, Taksir T, Lord RS, Freeman MW Evidence that dendritic cells infiltrate atherosclerotic lesions in apolipoprotein E-deficient mice. Histol Histopathol. 2001;16(3):801-8 - PMID: 11510970 - DOI: 10.14670/HH-16.801

  • Moore KJ, Fitzgerald ML, Freeman MW Peroxisome proliferator-activated receptors in macrophage biology: friend or foe?. Curr Opin Lipidol. 2001;12(5):519-27 - PMID: 11561171 - DOI: 10.1097/00041433-200110000-00007

  • Bernheiden M, Heinrich JM, Minigo G, Schütt C, Stelter F, Freeman M, Golenbock D, Jack RS LBP, CD14, TLR4 and the murine innate immune response to a peritoneal Salmonella infection. J Endotoxin Res. 2001;7(6):447-50 - PMID: 11753215

  • Wang X, Zeng W, Murakawa M, Freeman MW, Seed B Episomal segregation of the adenovirus enhancer sequence by conditional genome rearrangement abrogates late viral gene expression. J Virol. 2000;74(23):11296-303 - PMID: 11070029 - PMCID: PMC113234 - DOI: 10.1128/jvi.74.23.11296-11303.2000

  • M Freeman, Consultant editor 2nd edition. PJ Skerret and SD Emond What to do about high cholesterol. President and Fellows of Harvard College. Harvard Health Publications. 2000;:ePub

  • Fabunmi RP, Moore KJ, Libby P, Freeman MW Stromelysin-1 (MMP-3) expression driven by a macrophage-specific promoter results in reduced viability in transgenic mice. Atherosclerosis. 2000;148(2):375-86 - PMID: 10657574 - DOI: 10.1016/s0021-9150(99)00405-0

  • Fitzgerald ML, Moore KJ, Freeman MW, Reed GL Lipopolysaccharide induces scavenger receptor A expression in mouse macrophages: a divergent response relative to human THP-1 monocyte/macrophages. J Immunol. 2000;164(5):2692-700 - PMID: 10679110 - DOI: 10.4049/jimmunol.164.5.2692

  • Brousseau ME, Schaefer EJ, Dupuis J, Eustace B, Van Eerdewegh P, Goldkamp AL, Thurston LM, FitzGerald MG, Yasek-McKenna D, O'Neill G, Eberhart GP, Weiffenbach B, Ordovas JM, Freeman MW, Brown RH, Gu JZ Novel mutations in the gene encoding ATP-binding cassette 1 in four tangier disease kindreds. J Lipid Res. 2000;41(3):433-41 - PMID: 10706591

  • Brousseau ME, Eberhart GP, Dupuis J, Asztalos BF, Goldkamp AL, Schaefer EJ, Freeman MW Cellular cholesterol efflux in heterozygotes for tangier disease is markedly reduced and correlates with high density lipoprotein cholesterol concentration and particle size. J Lipid Res. 2000;41(7):1125-35 - PMID: 10884295

  • Moore KJ, Andersson LP, Ingalls RR, Monks BG, Li R, Arnaout MA, Golenbock DT, Freeman MW Divergent response to LPS and bacteria in CD14-deficient murine macrophages. J Immunol. 2000;165(8):4272-80 - PMID: 11035061 - DOI: 10.4049/jimmunol.165.8.4272

  • Wang X, Zeng W, Murakawa M, Freeman MW, Seed B Episomal segregation of the adenovirus enhancer sequence by conditional genome rearrangement abrogates late viral gene expression. J Virol. 2000;74(23):11296-303 - PMID: 11070029 - PMCID: PMC113234 - DOI: 10.1128/jvi.74.23.11296-11303.2000

  • Li Z, Kako Y, Pang L, Freeman MW, Glick JM, Wang X, Goldberg IJ Effects of overexpression of the amino-terminal fragment of apolipoprotein B on apolipoprotein B and lipoprotein production. J Lipid Res. 2000;41(12):1912-20 - PMID: 11108724

  • Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP, Tripp RA, Walsh EE, Freeman MW, Golenbock DT, Anderson LJ, Finberg RW Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol. 2000;1(5):398-401 - PMID: 11062499 - DOI: 10.1038/80833

  • Chiang N, Gronert K, Clish CB, O'Brien JA, Freeman MW, Serhan CN Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion. J Clin Invest. 1999;104(3):309-16 - PMID: 10430612 - PMCID: PMC408424 - DOI: 10.1172/JCI7016

  • Freeman MW Effluxed lipids: Tangier Island's latest export. Proc Natl Acad Sci U S A. 1999;96(20):10950-2 - PMID: 10500104 - PMCID: PMC34222 - DOI: 10.1073/pnas.96.20.10950

  • Eberhart GP, Mendez AJ, Freeman MW Decreased cholesterol efflux from fibroblasts of a patient without Tangier disease, but with markedly reduced high density lipoprotein cholesterol levels. J Clin Endocrinol Metab. 1998;83(3):836-46 - PMID: 9506737 - DOI: 10.1210/jcem.83.3.4642

  • Andersson L, Freeman MW Functional changes in scavenger receptor binding conformation are induced by charge mutants spanning the entire collagen domain. J Biol Chem. 1998;273(31):19592-601 - PMID: 9677385 - DOI: 10.1074/jbc.273.31.19592

  • Moore KJ, Fabunmi RP, Andersson LP, Freeman MW In vitro-differentiated embryonic stem cell macrophages: a model system for studying atherosclerosis-associated macrophage functions. Arterioscler Thromb Vasc Biol. 1998;18(10):1647-54 - PMID: 9763539 - DOI: 10.1161/01.atv.18.10.1647

  • Freeman MW Scavenger receptors in atherosclerosis. Curr Opin Hematol. 1997;4(1):41-7 - PMID: 9050378 - DOI: 10.1097/00062752-199704010-00007

  • Christie RH, Freeman M, Hyman BT Expression of the macrophage scavenger receptor, a multifunctional lipoprotein receptor, in microglia associated with senile plaques in Alzheimer's disease. Am J Pathol. 1996;148(2):399-403 - PMID: 8579103 - PMCID: PMC1861668

  • Haydock GS and MW Freeman Screening for hyperlipidemia. In: Goroll A, May L, Mulley A, eds. 1995. 1995;Primary Care Medicine, 3rd Edit:72-75

  • Li H, Freeman MW, Libby P Regulation of smooth muscle cell scavenger receptor expression in vivo by atherogenic diets and in vitro by cytokines. J Clin Invest. 1995;95(1):122-33 - PMID: 7814605 - PMCID: PMC295387 - DOI: 10.1172/JCI117628

  • Aftring RP, Freeman MW Structure of the murine macrophage scavenger receptor gene and evaluation of sequences that regulate expression in the macrophage cell line, P388D. J Lipid Res. 1995;36(6):1305-14 - PMID: 7666008

  • Aftring RP and MW Freeman Of mice, men and cholesterol. Hepatology. 1994;19:1054-1056

  • MW Freeman Macrophage scavenger receptors. Current Opinions in Lipidology . 1994;5:143-148

  • Freeman MW Macrophage scavenger receptors. Curr Opin Lipidol. 1994;5(2):143-8 - PMID: 8044417 - DOI: 10.1097/00041433-199404000-00011

  • Aftring RP, Freeman MW Of mice, men and cholesterol. Hepatology. 1994;19(4):1054-6 - PMID: 8138246 - DOI: 10.1002/hep.1840190436

  • M Freeman, Consultant editor. PJ Skerret and SD Emond What to do about high cholesterol. President and Fellows of Harvard College. Harvard Health Publications. 1993;:ePub

  • Martin KA, and Freeman MW Postmenopausal hormone-replacement therapy . New Engl J Med. 1993;328:1115-1117

  • Retsky KL, Freeman MW, Frei B Ascorbic acid oxidation product(s) protect human low density lipoprotein against atherogenic modification. Anti- rather than prooxidant activity of vitamin C in the presence of transition metal ions. J Biol Chem. 1993;268(2):1304-9 - PMID: 8419332

  • Martin KA, Freeman MW Postmenopausal hormone-replacement therapy. N Engl J Med. 1993;328(15):1115-7 - PMID: 8455670 - DOI: 10.1056/NEJM199304153281509

  • Golenbock DT, Liu Y, Millham FH, Freeman MW, Zoeller RA Surface expression of human CD14 in Chinese hamster ovary fibroblasts imparts macrophage-like responsiveness to bacterial endotoxin. J Biol Chem. 1993;268(29):22055-9 - PMID: 7691822

  • Ashkenas J, Penman M, Vasile E, Acton S, Freeman M, Krieger M Structures and high and low affinity ligand binding properties of murine type I and type II macrophage scavenger receptors. J Lipid Res. 1993;34(6):983-1000 - PMID: 8394868

  • Segre GV, Abou-Samra AB, Jüppner H, Schipani E, Force T, Urena P, Freeman M, Kong XF, Kolakowski LF, Hock J Characterization of cloned PTH/PTHrP receptors. J Endocrinol Invest. 1993;15(9 Suppl 6):11-7 - PMID: 1338633

  • Bickel PE, Freeman MW Rabbit aortic smooth muscle cells express inducible macrophage scavenger receptor messenger RNA that is absent from endothelial cells. J Clin Invest. 1992;90(4):1450-7 - PMID: 1401078 - PMCID: PMC443191 - DOI: 10.1172/JCI116012

  • Abou-Samra AB, Jüppner H, Force T, Freeman MW, Kong XF, Schipani E, Urena P, Richards J, Bonventre JV, Potts JT Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. Proc Natl Acad Sci U S A. 1992;89(7):2732-6 - PMID: 1313566 - PMCID: PMC48736 - DOI: 10.1073/pnas.89.7.2732

  • Jüppner H, Abou-Samra AB, Freeman M, Kong XF, Schipani E, Richards J, Kolakowski LF, Hock J, Potts JT, Kronenberg HM A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide. Science. 1991;254(5034):1024-6 - PMID: 1658941 - DOI: 10.1126/science.1658941

  • Freeman M, Ekkel Y, Rohrer L, Penman M, Freedman NJ, Chisolm GM, Krieger M Expression of type I and type II bovine scavenger receptors in Chinese hamster ovary cells: lipid droplet accumulation and nonreciprocal cross competition by acetylated and oxidized low density lipoprotein. Proc Natl Acad Sci U S A. 1991;88(11):4931-5 - PMID: 2052575 - PMCID: PMC51781 - DOI: 10.1073/pnas.88.11.4931

  • Atkinson MJ, Freeman MW, Kronenberg HM Thymosin beta 4 is expressed in ROS 17/2.8 osteosarcoma cells in a regulated manner. Mol Endocrinol. 1990;4(1):69-74 - PMID: 2325669 - DOI: 10.1210/mend-4-1-69

  • Freeman M, Ashkenas J, Rees DJ, Kingsley DM, Copeland NG, Jenkins NA, Krieger M An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors. Proc Natl Acad Sci U S A. 1990;87(22):8810-4 - PMID: 1978939 - PMCID: PMC55049 - DOI: 10.1073/pnas.87.22.8810

  • Rohrer L, Freeman M, Kodama T, Penman M, Krieger M Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II. Nature. 1990;343(6258):570-2 - PMID: 2300208 - DOI: 10.1038/343570a0

  • Kodama T, Freeman M, Rohrer L, Zabrecky J, Matsudaira P, Krieger M Type I macrophage scavenger receptor contains alpha-helical and collagen-like coiled coils. Nature. 1990;343(6258):531-5 - PMID: 2300204 - DOI: 10.1038/343531a0

  • Freeman MW, Rigotti NA, and T. Force Risk factors in coronary artery disease and cardiac rehabilitation. In: Haber E, Eagle KA, Austen WG, eds. The Practice of Cardiology. 1989;:563-614

  • Wiren KM, Ivashkiv L, Ma P, Freeman MW, Potts JT, Kronenberg HM Mutations in signal sequence cleavage domain of preproparathyroid hormone alter protein translocation, signal sequence cleavage, and membrane-binding properties. Mol Endocrinol. 1989;3(2):240-50 - PMID: 2710131 - DOI: 10.1210/mend-3-2-240

  • Powers TA, Partain CL, Kessler RM, Freeman MW, Robertson RH, Wyatt SH, Whelan HT Central nervous system lesions in pediatric patients: Gd-DTPA-enhanced MR imaging. Radiology. 1988;169(3):723-6 - PMID: 3055036 - DOI: 10.1148/radiology.169.3.3055036

  • Kronenberg HM, Wiren KM, Freeman MW, JT Potts Jr Preproparathyroid hormone: Use of mutants to study secretion. In: Cohn DV, Martin TJ, Meunier PJ, eds. Calcium Regulation and Bone Metabolism: Basic and Clinical Aspects, Vol. 9. Amsterdam: Excerpta Medica. 1987;9:773-777

  • Wiren KM, Freeman MW, Potts JT Jr, HM Kronenberg Preproparathyroid hormone: a model for analyzing the secretory pathway. Ann NY Acad Sci. 1987;493:43-49

  • Potts, JT Jr, Nussbaum S, Wiren K, Freeman M, Igarashi T, Okazaki T, Zajac J, Abou-Samra AB, Bringhurst FR, Segre G, HM Kronenberg Chemistry, molecular biology, and mode of action of parathyroid hormone. Proceedings of the First International Conference on New Actions of Parathyroid Hormone. Kobe, Japan. 1987;:ePub

  • Wiren KM, Freeman MW, Potts JT, Kronenberg HM Preproparathyroid hormone. A model for analyzing the secretory pathway. Ann N Y Acad Sci. 1987;493:43-9 - PMID: 3473968 - DOI: 10.1111/j.1749-6632.1987.tb27179.x

  • Freeman MW, Wiren KM, Rapoport A, Lazar M, Potts JT, Kronenberg HM Consequences of amino-terminal deletions of preproparathyroid hormone signal sequence. Mol Endocrinol. 1987;1(9):628-38 - PMID: 3153480 - DOI: 10.1210/mend-1-9-628

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