Faculty Laboratories
The CCIB is the home of laboratories for a number of members of the
Harvard faculty. Click on any of the names or photos for more background
information about them.
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| Fred
Ausubel |
Frederick M. Ausubel is Professor of Genetics at Harvard
Medical School and the Ernst Winnacker Distinguished Investigator
in the Department of Molecular Biology at Massachusetts General Hospital.
Dr. Ausubel’s scientific work is primarily focused on host-microbe
interactions.
Dr. Ausubel was elected to the National Academy of Sciences in 1994,
the American Academy of Microbiology in 2002, and the American Academy
of Arts and Sciences in 2003. In addition to serving on a variety
of editorial boards, Dr. Ausubel is founding editor of the widely-read
Current Protocols in Molecular Biology. |
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| Mason Freeman |
Dr. Freeman graduated from Harvard College and received his M.D.
at the University of California, San Francisco in 1979. Following
clinical training, he worked as a post-doctoral research fellow in
the Biology Department of the Massachusetts Institute of Technology
before returning to the MGH to head the Cardiovascular Health Center.
He became Chief of the Lipid Metabolism Unit at the MGH in 1992.
Mason’s research work has centered on the role of macrophages
in atherosclerosis with particular interest in the trafficking of
lipids through these cells. |
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| Deborah Hung |
Deborah Hung is the most recent faculty member to join the CCIB. She is a physician-scientist combining chemical and genomic approaches to define host-pathogen interactions and to reveal the critical pressure points of infectious disease. Deborah received her Ph.D. in chemistry from Harvard University, and her M.D. from Harvard Medical School.
She holds positions as an infectious disease physician at Brigham and Women's Hospital and Massachusetts General Hospital,and an attending critical care physician in the Medical Intensive Care Unit at Brigham and Women's Hospital. |
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| J. Keith Joung |
J. Keith Joung is Assistant Professor of Pathology at Harvard Medical School and Assistant Pathologist and Director of the Molecular Pathology Unit at Massachusetts General Hospital. His research interests include understanding how Cys2His2 zinc fingers, the most common domain encoded in the human genome, mediate specific protein-DNA and protein-protein interactions and using cell-based selection methodologies to engineer artificial “designer” zinc finger domains.
Keith received his undergraduate degree from Harvard College and his M.D. and Ph.D. degrees from Harvard Medical School.
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| Gary
Ruvkun |
Gary Ruvkun is Professor of Genetics at Harvard Medical School.
His lab uses C. elegans molecular
genetics and genomics to study problems in developmental biology and
physiology. Dr. Ruvkun is a graduate of UC Berkeley and Harvard. Dr.
Ruvkun discovered that the nif genes are conserved over 3 billion
years of prokaryotic evolution, which prepared him for the comparative
genomics of the more recent past.
Dr. Ruvkun began to work with C. elegans
as a postdoc with Bob Horvitz at MIT and Walter Gilbert at Harvard,
where he explored the heterochronic genes that control the temporal
dimension of development. |
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| Brian
Seed |
Dr. Seed is the Director of the Center for Computational and Integrative
Biology and Professor of Genetics at Harvard. A graduate of CalTech,
he received both his B.S. and Ph.D. degrees there. Dr. Seed is the
author of numerous publications molecular biology, genomics and proteomics.
He holds numerous patents; see his CV for a list.
Brian's laboratories include groups in automation, bioinformatics,
chemistry, microarrays, proteomics, selection, sequencing and synthesis,
in addition to his own Seed Lab.
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| Lynda Stuart |
Lynda Stuart is a physician-scientist and received her medical degrees from University of Cambridge and University of London. She is a member of the Royal College of Physicians, UK. She trained in internal medicine and nephrology in the UK, working in London, Oxford and Edinburgh.
Her interest is in the role of innate immunity and phagocytosis both in the context of tissue remodeling and of host-pathogen interactions.
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| Jack Szostak |
Dr. Szostak is an Investigator of the Howard Hughes Medical Institute,
Professor of Genetics at Harvard Medical School, and the Alex Rich
Distinguished Investigator in the Department of Molecular Biology
at the Massachusetts General Hospital. His current research interests
are in the laboratory synthesis of self-replicating systems and the
origin of life.
Dr. Szostak is a member of the National Academy of Sciences, and a
Fellow of the New York Academy of Sciences and the American Academy
of Arts and Sciences. In 2000, Dr. Szostak was awarded the Medal of
the Genetics Society of America. |
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| Ron Tompkins |
Ron Tompkins graduated Summa Cum Laude from Tulane University Medical
School and holds a doctorate in chemical and biomedical engineering
from the Massachusetts Institute of Technology.
Dr. Tompkins is the Chief of Burns Service at the Massachusetts
General Hospital, the John Frances Burke Professor of Surgery at
Harvard Medical School, and he also serves as Chief of Staff of
Shriners Hospital for Children in Boston.
Dr. Tompkins' primary research interests are in physiology of inflammation
and burn healing. |
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| Jia
Wolfe |
Dr. Wolfe has extensive research and management experience in the
biotech industry and has a special interest in drug discovery and
interdisciplinary research in chemistry and biology. She currently
directs a drug discovery group within the Center for Computational
and Integrative Biology.
Her training under Professor Thomas W. Bell piqued her interest in
the life sciences. Dr. Wolfe’s interdisciplinary expertise was
further developed during her postdoctoral work at Harvard University
with Professor Gregory Verdine, a leader in the field of chemical
biology working at the interface of chemistry, molecular biology,
and structural biology.
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| Ramnik
Xavier |
Ramnik Xavier is Assistant Professor of Medicine at Harvard Medical
School and attending physician in the Gastrointestinal Unit at Massachusetts
General Hospital.
He is Board certified in Medicine and Gastroenterology. Following
clinical training, he completed his post-doctoral fellowship with
Brian Seed in the Department of Molecular Biology at the MGH Department
of Genetics at Harvard Medical School. While in the Seed lab, Ramnik
and his colleagues demonstrated that lipid rafts play an important
role in T cell signaling. His current research focuses on PDZ proteins
in cell signaling and genomic approaches for dissecting novel pathways
in inflammation and cancer. |
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